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The map label for this gene is ycgM [C]

Identifier: 218532265

GI number: 218532265

Start: 4618375

End: 4619259

Strand: Reverse

Name: ycgM [C]

Synonym: Mchl_4377

Alternate gene names: 218532265

Gene position: 4619259-4618375 (Counterclockwise)

Preceding gene: 218532267

Following gene: 218532263

Centisome position: 79.95

GC content: 68.36

Gene sequence:

>885_bases
ATGAAGTTGATCCGGCACGGAGCGAGCGGTGACGAGAAGCCGGGCCTCGTGGATGCGAAGGGCGGCTTGCGCGACCTGTC
GGGAACCCTGCGTGATCTTGCCGGACCGGGCCTCTCACGGGAATCGCTCGACCGACTCGCGCGGATCGACCCTGAAAGCC
TGCCGCTGCTGCCGCCCGGCACCCGCCTCGGCCCCTGCGTTGGCGGCACCCGCAACTTCGTGGCGATCGGCCTGAACTAC
GCCGACCACGCCGCCGAGACCGGGGCCGCGATCCCGGCCGAGCCGATCATCTTCAACAAGGCGCCCTCCTGCATCGTCGG
CCCCAACGACACGGTGATCCTGCCCAAAGCCTCGGCCAAGACCGACTGGGAGGTGGAACTCGCCGTGGTGATCGGCGCCC
GCGCCTCCTACGTTCATGCCAACGAGGCGCTGCGCTACGTGGCGGGCGTGTGCATCTGCAACGACCTGTCTGAGCGCGAA
TTCCAGATGGAGCGCGGCGGCACCTGGACCAAGGGCAAGGGCTGCCCGACCTTCGGCCCGCTCGGCCCCTGGCTCGTCAC
CCTCGACGAGATCCCGGACCTGAAGAACCTCTCGATGAGCCTCGATCTCAACGGTCGGCGGATGCAGTCGGGCTCGACCG
CGACGATGATCTTCGACGTGGCGCAGATCGTCGCCTACGTCTCGCATTTCATGATGCTGGAGCCCGGCGACGTCATCACC
ACTGGCACCCCGCCGGGCGTCGGCCTCGGCATGAAGCCGCCGCGCTACCTCAGAAGCGACGACGAGATGGTGCTGCGCAT
CGACGGCCTCGGCGAGCAGCGCCAGCGGGTCGTGGCCTTCGACGACTGGACCGCCAAGGTCGCCGCCGGCGAACCGACGA
ACTGA

Upstream 100 bases:

>100_bases
GCGGTGAATGTGATCGCGCGGTGCCGCTTGCACCCCGGATCGGTCGCGGCCATGCTCGCGCACCTCTAGTTGAGCCTCGA
GCAGGACGGAGACGCCGACG

Downstream 100 bases:

>100_bases
CGCACGGCACAGGGTTCTCCAACGGGGCCGACGAGGCTTGCCCCCCGCCGCACCGGCCCGGTCGTCTTCCTCGGCGGCGG
ACCGGTCACCGGCGCAGCGG

Product: 5-carboxymethyl-2-hydroxymuconate delta-isomerase

Products: NA

Alternate protein names: UGL; Ureidoglycolase; Ureidoglycolatase; Ureidoglycolate hydrolase [H]

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MKLIRHGASGDEKPGLVDAKGGLRDLSGTLRDLAGPGLSRESLDRLARIDPESLPLLPPGTRLGPCVGGTRNFVAIGLNY
ADHAAETGAAIPAEPIIFNKAPSCIVGPNDTVILPKASAKTDWEVELAVVIGARASYVHANEALRYVAGVCICNDLSERE
FQMERGGTWTKGKGCPTFGPLGPWLVTLDEIPDLKNLSMSLDLNGRRMQSGSTATMIFDVAQIVAYVSHFMMLEPGDVIT
TGTPPGVGLGMKPPRYLRSDDEMVLRIDGLGEQRQRVVAFDDWTAKVAAGEPTN

Sequences:

>Translated_294_residues
MKLIRHGASGDEKPGLVDAKGGLRDLSGTLRDLAGPGLSRESLDRLARIDPESLPLLPPGTRLGPCVGGTRNFVAIGLNY
ADHAAETGAAIPAEPIIFNKAPSCIVGPNDTVILPKASAKTDWEVELAVVIGARASYVHANEALRYVAGVCICNDLSERE
FQMERGGTWTKGKGCPTFGPLGPWLVTLDEIPDLKNLSMSLDLNGRRMQSGSTATMIFDVAQIVAYVSHFMMLEPGDVIT
TGTPPGVGLGMKPPRYLRSDDEMVLRIDGLGEQRQRVVAFDDWTAKVAAGEPTN
>Mature_294_residues
MKLIRHGASGDEKPGLVDAKGGLRDLSGTLRDLAGPGLSRESLDRLARIDPESLPLLPPGTRLGPCVGGTRNFVAIGLNY
ADHAAETGAAIPAEPIIFNKAPSCIVGPNDTVILPKASAKTDWEVELAVVIGARASYVHANEALRYVAGVCICNDLSERE
FQMERGGTWTKGKGCPTFGPLGPWLVTLDEIPDLKNLSMSLDLNGRRMQSGSTATMIFDVAQIVAYVSHFMMLEPGDVIT
TGTPPGVGLGMKPPRYLRSDDEMVLRIDGLGEQRQRVVAFDDWTAKVAAGEPTN

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=229, Percent_Identity=46.7248908296943, Blast_Score=202, Evalue=2e-52,
Organism=Homo sapiens, GI40786394, Length=229, Percent_Identity=45.4148471615721, Blast_Score=195, Evalue=5e-50,
Organism=Homo sapiens, GI66348062, Length=204, Percent_Identity=36.7647058823529, Blast_Score=124, Evalue=7e-29,
Organism=Homo sapiens, GI215422413, Length=203, Percent_Identity=35.4679802955665, Blast_Score=124, Evalue=8e-29,
Organism=Homo sapiens, GI13654274, Length=204, Percent_Identity=36.7647058823529, Blast_Score=124, Evalue=1e-28,
Organism=Escherichia coli, GI1787428, Length=199, Percent_Identity=35.1758793969849, Blast_Score=119, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17557057, Length=188, Percent_Identity=34.5744680851064, Blast_Score=117, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6324161, Length=219, Percent_Identity=30.5936073059361, Blast_Score=90, Evalue=5e-19,
Organism=Drosophila melanogaster, GI28572127, Length=281, Percent_Identity=37.7224199288256, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24663695, Length=217, Percent_Identity=33.6405529953917, Blast_Score=124, Evalue=6e-29,
Organism=Drosophila melanogaster, GI28571789, Length=179, Percent_Identity=37.4301675977654, Blast_Score=117, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.3.2.3 [H]

Molecular weight: Translated: 31404; Mature: 31404

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLIRHGASGDEKPGLVDAKGGLRDLSGTLRDLAGPGLSRESLDRLARIDPESLPLLPPG
CCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCC
TRLGPCVGGTRNFVAIGLNYADHAAETGAAIPAEPIIFNKAPSCIVGPNDTVILPKASAK
CCCCCCCCCCCCEEEEECCCHHHHHHCCCCCCCCCEEECCCCCEEECCCCCEEEECCCCC
TDWEVELAVVIGARASYVHANEALRYVAGVCICNDLSEREFQMERGGTWTKGKGCPTFGP
CCCEEEEEEEEECCCCEEEHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCC
LGPWLVTLDEIPDLKNLSMSLDLNGRRMQSGSTATMIFDVAQIVAYVSHFMMLEPGDVIT
CCCEEEECCCCCCCCCCEEEEECCCCEECCCCCCHHHHHHHHHHHHHHHHEEECCCCEEE
TGTPPGVGLGMKPPRYLRSDDEMVLRIDGLGEQRQRVVAFDDWTAKVAAGEPTN
CCCCCCCCCCCCCCHHHCCCCCEEEEEECCCCCCCEEEEEECCEEEEECCCCCC
>Mature Secondary Structure
MKLIRHGASGDEKPGLVDAKGGLRDLSGTLRDLAGPGLSRESLDRLARIDPESLPLLPPG
CCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCC
TRLGPCVGGTRNFVAIGLNYADHAAETGAAIPAEPIIFNKAPSCIVGPNDTVILPKASAK
CCCCCCCCCCCCEEEEECCCHHHHHHCCCCCCCCCEEECCCCCEEECCCCCEEEECCCCC
TDWEVELAVVIGARASYVHANEALRYVAGVCICNDLSEREFQMERGGTWTKGKGCPTFGP
CCCEEEEEEEEECCCCEEEHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCC
LGPWLVTLDEIPDLKNLSMSLDLNGRRMQSGSTATMIFDVAQIVAYVSHFMMLEPGDVIT
CCCEEEECCCCCCCCCCEEEEECCCCEECCCCCCHHHHHHHHHHHHHHHHEEECCCCEEE
TGTPPGVGLGMKPPRYLRSDDEMVLRIDGLGEQRQRVVAFDDWTAKVAAGEPTN
CCCCCCCCCCCCCCHHHCCCCCEEEEEECCCCCCCEEEEEECCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA