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The map label for this gene is gbh [H]

Identifier: 218532180

GI number: 218532180

Start: 4532469

End: 4533506

Strand: Reverse

Name: gbh [H]

Synonym: Mchl_4292

Alternate gene names: 218532180

Gene position: 4533506-4532469 (Counterclockwise)

Preceding gene: 218532182

Following gene: 218532176

Centisome position: 78.46

GC content: 74.08

Gene sequence:

>1038_bases
ATGGCGGATGAGAGCGAATCGGCGGGCGCGCGGGCGCAACGCTTGGCGCGGTTCCAGCCGGCCTCGGGGATGGTGACGCC
ACGCTTCTCGGGGCTTGCGAGCTTCATGCGGCTGCCGGTGCTCGATCCCGTCGAGGCGGTGGGCGACGGGGTCGGCGAAG
GGGCTGGCGAAGGGACTGGACTGATCGAGATCGGCCTGATCGGCATCCCCTTCGACGGCACCACCACCAACCGCCCCGGC
GCCCGGCTCGGGCCGCGGGCCGTGCGCGAGGCCTCCACCGGCACGCGGGCGCTCAACCACGCCACAGGGGTGGCGCCCTA
CGCCCTGGCGGCCTGCGCCGATCTCGGCGACGTGCCGGTCAACCCGGTGGACGCCGCCGAGACCGCACGGCGGATCGAGG
CGTTCTACCGGCCGCTCGCCGAGGCCGGGATCGTGCCGCTCACGGTCGGCGGCGACCATTTCGTCACCTATCCGGTGCTG
CGGGCGCTCGGGGCCGCCCGGCCGCTCGGGCTGATCCATATCGACGCTCACAGCGACACCGACGACTCCCAGTATGGCGG
GGCGCGGCTCACCCACGGCACGCCGTTCCGGCGCGCGGTCGAGGACGGGGTGCTCGACCCGCGGCGCTGCATCCAGATCG
GCATCCGCGGCAGCATGGATGCGGCCGACGAGCGCGACTGGGCCCTGGCGCAGGGCATGCGCATCCTCACGATGGAGGAG
GTCTGCGCCCGCGGCCTGCCGGAGGTGGCCGCGGAAGCCCGCGCCGTGACCGGCGACGGCCCGACCTATCTCAGCTTCGA
CATCGACGCCCTCGATCCCGCCTTCGCCCCCGGCACCGGCACGCCGGAGATCGGCGGCTTCACCACCCGCGAGGCGCTGC
ACCTGCTGCGGGCCCTGCGCGGCCTCGATCTCGTCGGGGCGGATGTGGTGGAGGTCGCCCCTCCGCTCGATTCCGCCGGC
ATCACGGCGCTGGCGGGCGCCGGCATCGCCTTCGAGATCCTGTGCCTGCTGGCCGAGCGGGTCGCAGCACGGCACTGA

Upstream 100 bases:

>100_bases
GCTTGCGGCCGGAGGAGACGGGCGGCTTGATGCGGAACGCGGGTGAGATCGCACCATCGCTGCAAGTGGCTGTGAAGACG
CCGCGCCGGGGAGGATCGTC

Downstream 100 bases:

>100_bases
CCGGCCCGAAAGACGGGACCCGCGAAAGGGAGAGCCTTGGCATGGAGGAATGCCTTTTGGGAATCCCGGGATCAGCTCCG
CACGGACGGTCCGCCCGCGG

Product: agmatinase

Products: NA

Alternate protein names: GBase; D-arginase [H]

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MADESESAGARAQRLARFQPASGMVTPRFSGLASFMRLPVLDPVEAVGDGVGEGAGEGTGLIEIGLIGIPFDGTTTNRPG
ARLGPRAVREASTGTRALNHATGVAPYALAACADLGDVPVNPVDAAETARRIEAFYRPLAEAGIVPLTVGGDHFVTYPVL
RALGAARPLGLIHIDAHSDTDDSQYGGARLTHGTPFRRAVEDGVLDPRRCIQIGIRGSMDAADERDWALAQGMRILTMEE
VCARGLPEVAAEARAVTGDGPTYLSFDIDALDPAFAPGTGTPEIGGFTTREALHLLRALRGLDLVGADVVEVAPPLDSAG
ITALAGAGIAFEILCLLAERVAARH

Sequences:

>Translated_345_residues
MADESESAGARAQRLARFQPASGMVTPRFSGLASFMRLPVLDPVEAVGDGVGEGAGEGTGLIEIGLIGIPFDGTTTNRPG
ARLGPRAVREASTGTRALNHATGVAPYALAACADLGDVPVNPVDAAETARRIEAFYRPLAEAGIVPLTVGGDHFVTYPVL
RALGAARPLGLIHIDAHSDTDDSQYGGARLTHGTPFRRAVEDGVLDPRRCIQIGIRGSMDAADERDWALAQGMRILTMEE
VCARGLPEVAAEARAVTGDGPTYLSFDIDALDPAFAPGTGTPEIGGFTTREALHLLRALRGLDLVGADVVEVAPPLDSAG
ITALAGAGIAFEILCLLAERVAARH
>Mature_344_residues
ADESESAGARAQRLARFQPASGMVTPRFSGLASFMRLPVLDPVEAVGDGVGEGAGEGTGLIEIGLIGIPFDGTTTNRPGA
RLGPRAVREASTGTRALNHATGVAPYALAACADLGDVPVNPVDAAETARRIEAFYRPLAEAGIVPLTVGGDHFVTYPVLR
ALGAARPLGLIHIDAHSDTDDSQYGGARLTHGTPFRRAVEDGVLDPRRCIQIGIRGSMDAADERDWALAQGMRILTMEEV
CARGLPEVAAEARAVTGDGPTYLSFDIDALDPAFAPGTGTPEIGGFTTREALHLLRALRGLDLVGADVVEVAPPLDSAGI
TALAGAGIAFEILCLLAERVAARH

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=336, Percent_Identity=44.6428571428571, Blast_Score=279, Evalue=3e-75,
Organism=Homo sapiens, GI10947139, Length=301, Percent_Identity=26.578073089701, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI4502215, Length=306, Percent_Identity=26.1437908496732, Blast_Score=79, Evalue=7e-15,
Organism=Escherichia coli, GI1789306, Length=311, Percent_Identity=39.5498392282958, Blast_Score=189, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI71996843, Length=218, Percent_Identity=30.7339449541284, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6325146, Length=212, Percent_Identity=31.6037735849057, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24638886, Length=286, Percent_Identity=26.2237762237762, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.7; =3.5.3.10 [H]

Molecular weight: Translated: 35813; Mature: 35682

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADESESAGARAQRLARFQPASGMVTPRFSGLASFMRLPVLDPVEAVGDGVGEGAGEGTG
CCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCC
LIEIGLIGIPFDGTTTNRPGARLGPRAVREASTGTRALNHATGVAPYALAACADLGDVPV
EEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
NPVDAAETARRIEAFYRPLAEAGIVPLTVGGDHFVTYPVLRALGAARPLGLIHIDAHSDT
CCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCC
DDSQYGGARLTHGTPFRRAVEDGVLDPRRCIQIGIRGSMDAADERDWALAQGMRILTMEE
CCCCCCCEECCCCCHHHHHHHHCCCCHHHHHEECCCCCCCCCCCCHHHHHCCCCEEEHHH
VCARGLPEVAAEARAVTGDGPTYLSFDIDALDPAFAPGTGTPEIGGFTTREALHLLRALR
HHHCCCHHHHHHHEEECCCCCEEEEEEHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
GLDLVGADVVEVAPPLDSAGITALAGAGIAFEILCLLAERVAARH
CCCCCCCCHHHHCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ADESESAGARAQRLARFQPASGMVTPRFSGLASFMRLPVLDPVEAVGDGVGEGAGEGTG
CCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCC
LIEIGLIGIPFDGTTTNRPGARLGPRAVREASTGTRALNHATGVAPYALAACADLGDVPV
EEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
NPVDAAETARRIEAFYRPLAEAGIVPLTVGGDHFVTYPVLRALGAARPLGLIHIDAHSDT
CCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCC
DDSQYGGARLTHGTPFRRAVEDGVLDPRRCIQIGIRGSMDAADERDWALAQGMRILTMEE
CCCCCCCEECCCCCHHHHHHHHCCCCHHHHHEECCCCCCCCCCCCHHHHHCCCCEEEHHH
VCARGLPEVAAEARAVTGDGPTYLSFDIDALDPAFAPGTGTPEIGGFTTREALHLLRALR
HHHCCCHHHHHHHEEECCCCCEEEEEEHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
GLDLVGADVVEVAPPLDSAGITALAGAGIAFEILCLLAERVAARH
CCCCCCCCHHHHCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA