Click here to switch to the map view.

The map label for this gene is mdtA [H]

Identifier: 218532150

GI number: 218532150

Start: 4496740

End: 4497945

Strand: Reverse

Name: mdtA [H]

Synonym: Mchl_4262

Alternate gene names: 218532150

Gene position: 4497945-4496740 (Counterclockwise)

Preceding gene: 218532152

Following gene: 218532147

Centisome position: 77.85

GC content: 69.9

Gene sequence:

>1206_bases
GTGCGGTCAGGCGTCGGCTTCGTCATCACCGGCCTCGTCGTCGGCGCGCTCGGAATCGCCGGAGGGGCGTGGTGGGGGGC
CGGGCACCCGATCCCCGGCTTTCTCGCCCATCACCTCAAGGTGGCGGGCCGGGCCGGACCCAAGAAGAAGGAAGAACCGC
GGCTGGCGGTGAAGGCGGTGCGCGCCAGCCGCCAGGATGTGCCGGTCGCCTTCGAATATACCGGCACGATCGTCTCGCCC
CGTGACGCCGCACTGCAGGCTCGGGTGACCGGCTTCGTGATGGAGCGCCCGTTCGAGCCCGGCGGCCATGTGAAGAAGGG
TCAGGTGCTGTTCCGCATCGACCCGCGCCCGTTCGAGGTCGCCCTCAAATCGGCCGAGGCCCTGCGCGACCAAGCCAAGG
CCACCGTCTCCTTCGCCCAGGCCGAGGTGAACCGCACCGAGCAGCTCGCCGACAAGGGCTTCGCCACCGAGCAGCGCGCC
CAGCAGAACCAGTCGAACCTCGCCACCGCCACCGCCAAGCTCGAAGAGGCGGAGGCCGCCATCGCCCGCCAGCGGCTGAA
CCTCGAATACGCGGTGATCCGCGCGCCCTTCGACGGGCGCTCCAGCCTGTCCATGGCCAATATCGGCGACATGGTGATCG
AGAATCAGACCAGCCTCGTCTCCGTGGTGCAGGTGAACCCGATCGACGTGCAGATGGCGCTCTCCTCCGAGGATGCGGAG
GCGGTGCGGGTCGCTCAAGGAGAGGGGCGGGTGAAGGTCCAGCTCCTCGACGTGGGGCGCGAGCCCGTGCGCGAGGCCAC
GATCTACCGCCTCGACAACCGCTTCGATCCCCGCACCGGCCGCCGCCTGATCCAGGCCTGGCTCGACAATGCGGACGAGC
GCTATCTGCCCGGCCGGTTCGTGCGCGCCCGCATCGAGGTCGGCCGGCAGGATCGGCTCCTGGTGCCGACGGTCGCGCTC
TCGGCCCAGCTCGACCAGCAGGTGGTCTGGACCGTGGACGACACCGGCACGGTCCACATGACCGCGATCGAGGTCGGCGA
CGTCTACGGCGACAACACCGCCGTGCTCAAAGGCCTCAAGCCCGACACGCTGGTGGTCACCGACCACCTCCAGAGCCTGC
GCCAGAACCTCAAAGTCGAGCCGCGCATCGGCGACGAGGTCAGCGCCGTCGGCAACACCCCCGCCCAGGGCGAGGCGCGG
CACTGA

Upstream 100 bases:

>100_bases
ACCCGCGTGCAACGTGTTGGGACTCCGCGTGTTCCCTCCCGTGTCGCGCCCGGAACACATCCGGCGGGCGCCCCCGTCCT
GCTGTTGGAGAGTGGATTTC

Downstream 100 bases:

>100_bases
ATTCGGGGTTTCGAAAGGGCAAGCCCTTTCGCGGGTCCAGGGCGGAGCCCTGGTGGAGGGAAGCCGGGGCGCTGCCCCGG
CACCCCGCCAAAGGGATGAT

Product: efflux transporter RND family, MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MRSGVGFVITGLVVGALGIAGGAWWGAGHPIPGFLAHHLKVAGRAGPKKKEEPRLAVKAVRASRQDVPVAFEYTGTIVSP
RDAALQARVTGFVMERPFEPGGHVKKGQVLFRIDPRPFEVALKSAEALRDQAKATVSFAQAEVNRTEQLADKGFATEQRA
QQNQSNLATATAKLEEAEAAIARQRLNLEYAVIRAPFDGRSSLSMANIGDMVIENQTSLVSVVQVNPIDVQMALSSEDAE
AVRVAQGEGRVKVQLLDVGREPVREATIYRLDNRFDPRTGRRLIQAWLDNADERYLPGRFVRARIEVGRQDRLLVPTVAL
SAQLDQQVVWTVDDTGTVHMTAIEVGDVYGDNTAVLKGLKPDTLVVTDHLQSLRQNLKVEPRIGDEVSAVGNTPAQGEAR
H

Sequences:

>Translated_401_residues
MRSGVGFVITGLVVGALGIAGGAWWGAGHPIPGFLAHHLKVAGRAGPKKKEEPRLAVKAVRASRQDVPVAFEYTGTIVSP
RDAALQARVTGFVMERPFEPGGHVKKGQVLFRIDPRPFEVALKSAEALRDQAKATVSFAQAEVNRTEQLADKGFATEQRA
QQNQSNLATATAKLEEAEAAIARQRLNLEYAVIRAPFDGRSSLSMANIGDMVIENQTSLVSVVQVNPIDVQMALSSEDAE
AVRVAQGEGRVKVQLLDVGREPVREATIYRLDNRFDPRTGRRLIQAWLDNADERYLPGRFVRARIEVGRQDRLLVPTVAL
SAQLDQQVVWTVDDTGTVHMTAIEVGDVYGDNTAVLKGLKPDTLVVTDHLQSLRQNLKVEPRIGDEVSAVGNTPAQGEAR
H
>Mature_401_residues
MRSGVGFVITGLVVGALGIAGGAWWGAGHPIPGFLAHHLKVAGRAGPKKKEEPRLAVKAVRASRQDVPVAFEYTGTIVSP
RDAALQARVTGFVMERPFEPGGHVKKGQVLFRIDPRPFEVALKSAEALRDQAKATVSFAQAEVNRTEQLADKGFATEQRA
QQNQSNLATATAKLEEAEAAIARQRLNLEYAVIRAPFDGRSSLSMANIGDMVIENQTSLVSVVQVNPIDVQMALSSEDAE
AVRVAQGEGRVKVQLLDVGREPVREATIYRLDNRFDPRTGRRLIQAWLDNADERYLPGRFVRARIEVGRQDRLLVPTVAL
SAQLDQQVVWTVDDTGTVHMTAIEVGDVYGDNTAVLKGLKPDTLVVTDHLQSLRQNLKVEPRIGDEVSAVGNTPAQGEAR
H

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=332, Percent_Identity=29.8192771084337, Blast_Score=141, Evalue=9e-35,
Organism=Escherichia coli, GI1789929, Length=334, Percent_Identity=31.1377245508982, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789665, Length=355, Percent_Identity=28.169014084507, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1786668, Length=353, Percent_Identity=30.3116147308782, Blast_Score=101, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43649; Mature: 43649

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSGVGFVITGLVVGALGIAGGAWWGAGHPIPGFLAHHLKVAGRAGPKKKEEPRLAVKAV
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
RASRQDVPVAFEYTGTIVSPRDAALQARVTGFVMERPFEPGGHVKKGQVLFRIDPRPFEV
HHCCCCCCEEEEECCEEECCCHHHHHHHHHHHHEECCCCCCCCEECCEEEEEECCCCHHH
ALKSAEALRDQAKATVSFAQAEVNRTEQLADKGFATEQRAQQNQSNLATATAKLEEAEAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IARQRLNLEYAVIRAPFDGRSSLSMANIGDMVIENQTSLVSVVQVNPIDVQMALSSEDAE
HHHHHCCCEEEEEECCCCCCCCCCHHCCCCCEEECCCCEEEEEEECCEEEEEEECCCCCC
AVRVAQGEGRVKVQLLDVGREPVREATIYRLDNRFDPRTGRRLIQAWLDNADERYLPGRF
EEEEECCCCEEEEEEEECCCCHHHHHHHEEECCCCCCHHHHHHHHHHHCCCCCCCCCCHH
VRARIEVGRQDRLLVPTVALSAQLDQQVVWTVDDTGTVHMTAIEVGDVYGDNTAVLKGLK
EEEEECCCCCCCEEEEHHHHHHCCCCEEEEEECCCCEEEEEEEEECCCCCCCHHEEECCC
PDTLVVTDHLQSLRQNLKVEPRIGDEVSAVGNTPAQGEARH
CCEEEEHHHHHHHHHCCEECCCCCCCHHHCCCCCCCCCCCC
>Mature Secondary Structure
MRSGVGFVITGLVVGALGIAGGAWWGAGHPIPGFLAHHLKVAGRAGPKKKEEPRLAVKAV
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
RASRQDVPVAFEYTGTIVSPRDAALQARVTGFVMERPFEPGGHVKKGQVLFRIDPRPFEV
HHCCCCCCEEEEECCEEECCCHHHHHHHHHHHHEECCCCCCCCEECCEEEEEECCCCHHH
ALKSAEALRDQAKATVSFAQAEVNRTEQLADKGFATEQRAQQNQSNLATATAKLEEAEAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IARQRLNLEYAVIRAPFDGRSSLSMANIGDMVIENQTSLVSVVQVNPIDVQMALSSEDAE
HHHHHCCCEEEEEECCCCCCCCCCHHCCCCCEEECCCCEEEEEEECCEEEEEEECCCCCC
AVRVAQGEGRVKVQLLDVGREPVREATIYRLDNRFDPRTGRRLIQAWLDNADERYLPGRF
EEEEECCCCEEEEEEEECCCCHHHHHHHEEECCCCCCHHHHHHHHHHHCCCCCCCCCCHH
VRARIEVGRQDRLLVPTVALSAQLDQQVVWTVDDTGTVHMTAIEVGDVYGDNTAVLKGLK
EEEEECCCCCCCEEEEHHHHHHCCCCEEEEEECCCCEEEEEEEEECCCCCCCHHEEECCC
PDTLVVTDHLQSLRQNLKVEPRIGDEVSAVGNTPAQGEARH
CCEEEEHHHHHHHHHCCEECCCCCCCHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA