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The map label for this gene is yciL [C]

Identifier: 218532076

GI number: 218532076

Start: 4396389

End: 4398413

Strand: Reverse

Name: yciL [C]

Synonym: Mchl_4170

Alternate gene names: 218532076

Gene position: 4398413-4396389 (Counterclockwise)

Preceding gene: 218532077

Following gene: 218532075

Centisome position: 76.12

GC content: 76.3

Gene sequence:

>2025_bases
ATGACCGACATTCCAGACCCCTCCCCGGCCGTGCCCGCGGACCAACCCGCCGCGCCCGAGGGCGAGCGCATCGCCAAGGC
CATCGCCCGCGCCGGCATCGCTTCCCGCCGCGACGCGGAGGCCCTGATCGAGGCCGGCCGCGTCACCCTCAATGGCAAGG
TTTTGACCTCGCCGGCGATCAACGTCACCGATTCCGATCGCATTACGGTGGACGACGAGCCCCTGCCCGCCCGCGAGCGG
ACCCGGCTGTGGCTGCTGCACAAGCCGCGCGGCGTCGTCACCACCGCCCGCGACCCGGAGGGCCGCCCGACGGTGTTCGA
CGGCCTGCCCGAAGAGCTGCCGCGGGTCGTCGCCATCGGCCGGCTCGACATCAACACCGAAGGGCTGCTGCTCCTCACCA
ATGACGGGGGGCTGGCCAAGGTGATCGCCCATCCCGATACCGGCTGGCTGCGCCGCTACCGGGTGCGCGCCTTCGGTGAC
GTGACCCAGCCCGATCTCGACAAGCTCAAGAAGGGCCTGACCGTCGACGGCATGGAGTACGGCCCGATCGAGGCGACCCT
CGACCGGGCGCAGGGCGACAACGTCTGGCTGACGCTCGGCCTGCGCGAGGGCAAGAACCGCGAGGTCAAGCGCATCCTCG
AGCATCTCGGCCTGTCGGTGAACCGGCTGATCCGGCTCTCGTTCGGACCGTTCCAACTCGGCGACCTCGAAGTCGGCCTC
GTTGAGGAGATCCGCACCAAGGTTCTGAAGGACCAGCTCGGAAAGAACCTCGCCGAGCAGGCCGGCGTCGATTTCGAGAG
CCCGGTGCGCGAGACGATCGCCCCCTTCGGCAGCCCGAAGAAGGCCACCCGCGCCACGCAGGCGGCGCCCGCAGGACGGG
GCCGTCAAGGCGCGCGCGACGAGGGCGCCTCGGAGCCCCGCTCGGGGTCTCGCGGCGGCTCGGCCGGCCGTCCGCCGCGC
GATCCCGCCCGCCCTGCCGCCCCCCGCGCCGGGGCACGCCCGGCCCCGCGTCCCCCTTCCCCGACCGTGTGGCGCGCCGA
CGAGGAGACGCGGCCTCGCGCCTCGAAGGTGCCGCGCCGGGGCATGGACCCCAAGACCGCCCGCGCGGCGGCGGCCGAGC
GCGGCCGCGAGCGGGTCGGCGCGATCCAGGCGGCCGGCGAGCGCCGGGTGCTGGTGGAGCGGCTTCAGCCCTCGCCAGAG
AAGCCCGCACCCGAGCCGCATCGCCGGGTCCGCTTCCGCAACGAGGAGGAGCGGTCCGCGCCCCGCGACAGGGCGCGCGA
AGACAGGCCGCGCCAGGATCGGCCAGGTCAAGATCGGCCGCGTGAAGACCGGCCGCGCGATGACAGGCCGCGCAGCGAGG
GACCGCGCGAGAACCGCGCCCGCGACGAGCGGCCGGGCCGGGACGAGTTCCGACGCGGCGCACCCGCGGGCGATGCCCGT
CCCCGCCGCCGTGAGGCCGGGGAGGCCGCACCGGCCGAGCGGCGCGGGCCGCCCCGCGAGCGTCCGTCCGATTTCGAGGG
GAGTCCGCCGCGCGAGCGGAGCGAGGGCCGGCCCCAGCGTGACTTCCATGGTGACTCCCGTGAGCGCGGCGAGGGCGCAC
CCCGCCGCGAGCGGCCGAGCGAAGGGCGCCCGCCCGAGCGTCGCGGCCCCCCGCGCGACCGGCCCCGTGCCGCCGAGGGC
GAGCGGCCGGCCCGCCCCCCGCGCAGTGCCGAGGCGTCCGATCGTCCCGCCTTCCGCAAGGGCCCCGGCAAGGGGCCCGG
TGGTGGTGCAGGCAAGAGCTTCGGCGGCAAGCCCGGCTTCAAGGGCGGTGACCGCGACGGCGCCAGGGGCGATTTCAAGG
GCGGCGCGAAAGGTGGCCCGCGGGGCGACTTCAAGCCCGGTGGCGGCGGCCGGCCTGGTGGGCGCCCGGGCGGACGTCCC
GGCGGCAAGCCCGGCGGTGCCCCCGGGGGACGCCCCGGCGGTGGCGGCAAGCCGGCACCGCGCGGGGGCGGCCGTCCGAG
CCGTCCGCCGCGTGGCGAGGGCTAA

Upstream 100 bases:

>100_bases
GCGACTGTGACCGACTTGAACCGCACGGTTCGATGAAAGGGCGGCCCTCGCGGGCCGCCTTTTCCTTTTGTGCAACCCGC
TGCTCTGATAAGGGGCGCGG

Downstream 100 bases:

>100_bases
GGGGCTTCGCGCGTGCGGATCGTCGGCGGCGAATGGCGCGGGCGCAGGCTGGTCGGACCGAAGGCGGAGGGCATCCGCCC
GACCTCCGACCGCCTGCGCG

Product: RNA-binding S4 domain protein

Products: NA

Alternate protein names: RNA pseudouridylate synthase; RNA-uridine isomerase [H]

Number of amino acids: Translated: 674; Mature: 673

Protein sequence:

>674_residues
MTDIPDPSPAVPADQPAAPEGERIAKAIARAGIASRRDAEALIEAGRVTLNGKVLTSPAINVTDSDRITVDDEPLPARER
TRLWLLHKPRGVVTTARDPEGRPTVFDGLPEELPRVVAIGRLDINTEGLLLLTNDGGLAKVIAHPDTGWLRRYRVRAFGD
VTQPDLDKLKKGLTVDGMEYGPIEATLDRAQGDNVWLTLGLREGKNREVKRILEHLGLSVNRLIRLSFGPFQLGDLEVGL
VEEIRTKVLKDQLGKNLAEQAGVDFESPVRETIAPFGSPKKATRATQAAPAGRGRQGARDEGASEPRSGSRGGSAGRPPR
DPARPAAPRAGARPAPRPPSPTVWRADEETRPRASKVPRRGMDPKTARAAAAERGRERVGAIQAAGERRVLVERLQPSPE
KPAPEPHRRVRFRNEEERSAPRDRAREDRPRQDRPGQDRPREDRPRDDRPRSEGPRENRARDERPGRDEFRRGAPAGDAR
PRRREAGEAAPAERRGPPRERPSDFEGSPPRERSEGRPQRDFHGDSRERGEGAPRRERPSEGRPPERRGPPRDRPRAAEG
ERPARPPRSAEASDRPAFRKGPGKGPGGGAGKSFGGKPGFKGGDRDGARGDFKGGAKGGPRGDFKPGGGGRPGGRPGGRP
GGKPGGAPGGRPGGGGKPAPRGGGRPSRPPRGEG

Sequences:

>Translated_674_residues
MTDIPDPSPAVPADQPAAPEGERIAKAIARAGIASRRDAEALIEAGRVTLNGKVLTSPAINVTDSDRITVDDEPLPARER
TRLWLLHKPRGVVTTARDPEGRPTVFDGLPEELPRVVAIGRLDINTEGLLLLTNDGGLAKVIAHPDTGWLRRYRVRAFGD
VTQPDLDKLKKGLTVDGMEYGPIEATLDRAQGDNVWLTLGLREGKNREVKRILEHLGLSVNRLIRLSFGPFQLGDLEVGL
VEEIRTKVLKDQLGKNLAEQAGVDFESPVRETIAPFGSPKKATRATQAAPAGRGRQGARDEGASEPRSGSRGGSAGRPPR
DPARPAAPRAGARPAPRPPSPTVWRADEETRPRASKVPRRGMDPKTARAAAAERGRERVGAIQAAGERRVLVERLQPSPE
KPAPEPHRRVRFRNEEERSAPRDRAREDRPRQDRPGQDRPREDRPRDDRPRSEGPRENRARDERPGRDEFRRGAPAGDAR
PRRREAGEAAPAERRGPPRERPSDFEGSPPRERSEGRPQRDFHGDSRERGEGAPRRERPSEGRPPERRGPPRDRPRAAEG
ERPARPPRSAEASDRPAFRKGPGKGPGGGAGKSFGGKPGFKGGDRDGARGDFKGGAKGGPRGDFKPGGGGRPGGRPGGRP
GGKPGGAPGGRPGGGGKPAPRGGGRPSRPPRGEG
>Mature_673_residues
TDIPDPSPAVPADQPAAPEGERIAKAIARAGIASRRDAEALIEAGRVTLNGKVLTSPAINVTDSDRITVDDEPLPARERT
RLWLLHKPRGVVTTARDPEGRPTVFDGLPEELPRVVAIGRLDINTEGLLLLTNDGGLAKVIAHPDTGWLRRYRVRAFGDV
TQPDLDKLKKGLTVDGMEYGPIEATLDRAQGDNVWLTLGLREGKNREVKRILEHLGLSVNRLIRLSFGPFQLGDLEVGLV
EEIRTKVLKDQLGKNLAEQAGVDFESPVRETIAPFGSPKKATRATQAAPAGRGRQGARDEGASEPRSGSRGGSAGRPPRD
PARPAAPRAGARPAPRPPSPTVWRADEETRPRASKVPRRGMDPKTARAAAAERGRERVGAIQAAGERRVLVERLQPSPEK
PAPEPHRRVRFRNEEERSAPRDRAREDRPRQDRPGQDRPREDRPRDDRPRSEGPRENRARDERPGRDEFRRGAPAGDARP
RRREAGEAAPAERRGPPRERPSDFEGSPPRERSEGRPQRDFHGDSRERGEGAPRRERPSEGRPPERRGPPRDRPRAAEGE
RPARPPRSAEASDRPAFRKGPGKGPGGGAGKSFGGKPGFKGGDRDGARGDFKGGAKGGPRGDFKPGGGGRPGGRPGGRPG
GKPGGAPGGRPGGGGKPAPRGGGRPSRPPRGEG

Specific function: Unknown

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787524, Length=221, Percent_Identity=42.0814479638009, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI87081838, Length=186, Percent_Identity=34.4086021505376, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1790453, Length=203, Percent_Identity=32.512315270936, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788510, Length=212, Percent_Identity=30.6603773584906, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006145
- InterPro:   IPR018496
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 72731; Mature: 72600

Theoretical pI: Translated: 11.60; Mature: 11.60

Prosite motif: PS50889 S4 ; PS01149 PSI_RSU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDIPDPSPAVPADQPAAPEGERIAKAIARAGIASRRDAEALIEAGRVTLNGKVLTSPAI
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCEEECCEEEECCCC
NVTDSDRITVDDEPLPARERTRLWLLHKPRGVVTTARDPEGRPTVFDGLPEELPRVVAIG
CCCCCCEEEECCCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCHHCCCHHHHHHEEEEE
RLDINTEGLLLLTNDGGLAKVIAHPDTGWLRRYRVRAFGDVTQPDLDKLKKGLTVDGMEY
EEEECCCCEEEEECCCCEEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHCCCEECCCCC
GPIEATLDRAQGDNVWLTLGLREGKNREVKRILEHLGLSVNRLIRLSFGPFQLGDLEVGL
CCHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHEEEECCCCCCCCCCCHHH
VEEIRTKVLKDQLGKNLAEQAGVDFESPVRETIAPFGSPKKATRATQAAPAGRGRQGARD
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCC
EGASEPRSGSRGGSAGRPPRDPARPAAPRAGARPAPRPPSPTVWRADEETRPRASKVPRR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCHHCCCHHHHCCCC
GMDPKTARAAAAERGRERVGAIQAAGERRVLVERLQPSPEKPAPEPHRRVRFRNEEERSA
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHCC
PRDRAREDRPRQDRPGQDRPREDRPRDDRPRSEGPRENRARDERPGRDEFRRGAPAGDAR
CHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCHHHHHCCCCCCCCC
PRRREAGEAAPAERRGPPRERPSDFEGSPPRERSEGRPQRDFHGDSRERGEGAPRRERPS
CHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHCCCCCCCCCCC
EGRPPERRGPPRDRPRAAEGERPARPPRSAEASDRPAFRKGPGKGPGGGAGKSFGGKPGF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCC
KGGDRDGARGDFKGGAKGGPRGDFKPGGGGRPGGRPGGRPGGKPGGAPGGRPGGGGKPAP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RGGGRPSRPPRGEG
CCCCCCCCCCCCCC
>Mature Secondary Structure 
TDIPDPSPAVPADQPAAPEGERIAKAIARAGIASRRDAEALIEAGRVTLNGKVLTSPAI
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCEEECCEEEECCCC
NVTDSDRITVDDEPLPARERTRLWLLHKPRGVVTTARDPEGRPTVFDGLPEELPRVVAIG
CCCCCCEEEECCCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCHHCCCHHHHHHEEEEE
RLDINTEGLLLLTNDGGLAKVIAHPDTGWLRRYRVRAFGDVTQPDLDKLKKGLTVDGMEY
EEEECCCCEEEEECCCCEEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHCCCEECCCCC
GPIEATLDRAQGDNVWLTLGLREGKNREVKRILEHLGLSVNRLIRLSFGPFQLGDLEVGL
CCHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHEEEECCCCCCCCCCCHHH
VEEIRTKVLKDQLGKNLAEQAGVDFESPVRETIAPFGSPKKATRATQAAPAGRGRQGARD
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCC
EGASEPRSGSRGGSAGRPPRDPARPAAPRAGARPAPRPPSPTVWRADEETRPRASKVPRR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCHHCCCHHHHCCCC
GMDPKTARAAAAERGRERVGAIQAAGERRVLVERLQPSPEKPAPEPHRRVRFRNEEERSA
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHCC
PRDRAREDRPRQDRPGQDRPREDRPRDDRPRSEGPRENRARDERPGRDEFRRGAPAGDAR
CHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCHHHHHCCCCCCCCC
PRRREAGEAAPAERRGPPRERPSDFEGSPPRERSEGRPQRDFHGDSRERGEGAPRRERPS
CHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHCCCCCCCCCCC
EGRPPERRGPPRDRPRAAEGERPARPPRSAEASDRPAFRKGPGKGPGGGAGKSFGGKPGF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCC
KGGDRDGARGDFKGGAKGGPRGDFKPGGGGRPGGRPGGRPGGKPGGAPGGRPGGGGKPAP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RGGGRPSRPPRGEG
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA