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The map label for this gene is yajO [H]

Identifier: 218532067

GI number: 218532067

Start: 4385416

End: 4386450

Strand: Reverse

Name: yajO [H]

Synonym: Mchl_4161

Alternate gene names: 218532067

Gene position: 4386450-4385416 (Counterclockwise)

Preceding gene: 218532069

Following gene: 218532063

Centisome position: 75.92

GC content: 67.44

Gene sequence:

>1035_bases
ATGGAATACCGGCAGTTCGGACGCTCGGGCCTCAAGGTACCGGTGCTCAGCCTCGGCACCGCCACCTTCGGCGGCACCGA
CGCGTTCTTCCAGAACTGGGGCAGCACCGGCGTGGCCGAGGCGAGCCGTCTGATCGATCTCTGCCTCGATGCGGGCGTCA
ACTTCCTCGACACCGCCGACCTCTATTCGAGCGGCGATTCCGAAAAGATCCTCGGCGAGGCGATCAAGGGCCGCCGCGAC
CGGCTCCTGATCTCCACCAAGGCGACCTTCCGGGTCGGCGAGGACGTGAACGCCGTCGGCTCGTCGCGCCACCACCTGAT
CCGCGCCTGCGAGGCGAGCCTGAAACGGCTCCAGACCGACCATATCGACGTCTACTTCATGCACGGCTTCGACGCGCTGA
CGCCCGTCGAGGAGACCCTGCGGGCGCTCGACGACCTCACCCGTTCGGGCAAGATCGGCTATATCGGCGCCTCGAACTTC
TCCGGCTGGCAATTGATGAAGGCGCTGGCGACCTCGGAGAAGGAGGGGCTCGCCCGCTACGTCGTCTATCAGGGCTATTA
CTCGCTGATCGGCCGCCACTACGAGTGGGAGCTGATGCCGCTCGGCCTCGACCAGGGCGTCGGCCTGATGGTGTGGAGTC
CGCTGGGCTGGGGCCGGCTCACCGGCAAGATCCGGCGGGGGCAGGCGGCCTCGGGCGGGCGGTTATCCACGGCGAGCGGC
GCGGAGGGCGGTCCCACCGTCTCCGACGACTACCTCTACGATGTTGTCGATGCCCTCGACGCGGTCGCCGCCGAGACCGG
CAAGACGGTGCCGCAGGTGGCGCTGAACTGGCTGCTCAGCCGCCCGACCGTGTGCAACATCGTCATCGGCGCCCGCAACG
AGGAGCAGTTGAAGCAGAATCTCGGCGCGGTGGGCTGGTCGCTCACGCCCGACCAGATCGCCCGCCTCGACGCGGCGAGC
CGGGAAAATCCGATCTATCCGTATTGGCACCAGATCGGCTTCGACGAGCGCAACCCCAAGCCGACGGCTTGGTGA

Upstream 100 bases:

>100_bases
CGCCCGGTCCGCCGCATTGCCGGGGCGCGCCGGTCTCCTCAAGACGGGGGCGGGCGGCCTCTCAGGGCCGTTTCCCGACA
GCCACAGCGGAGTGACGGAC

Downstream 100 bases:

>100_bases
GGCGGGACGGGTCCGCCAAAAGCCCCTCTCCCCGCAGGCGGGGCGAGGGGACGCGTCCGCCATCGCCCCGGTGAGCCGTC
AACGGCCTCACATGCTGATC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MEYRQFGRSGLKVPVLSLGTATFGGTDAFFQNWGSTGVAEASRLIDLCLDAGVNFLDTADLYSSGDSEKILGEAIKGRRD
RLLISTKATFRVGEDVNAVGSSRHHLIRACEASLKRLQTDHIDVYFMHGFDALTPVEETLRALDDLTRSGKIGYIGASNF
SGWQLMKALATSEKEGLARYVVYQGYYSLIGRHYEWELMPLGLDQGVGLMVWSPLGWGRLTGKIRRGQAASGGRLSTASG
AEGGPTVSDDYLYDVVDALDAVAAETGKTVPQVALNWLLSRPTVCNIVIGARNEEQLKQNLGAVGWSLTPDQIARLDAAS
RENPIYPYWHQIGFDERNPKPTAW

Sequences:

>Translated_344_residues
MEYRQFGRSGLKVPVLSLGTATFGGTDAFFQNWGSTGVAEASRLIDLCLDAGVNFLDTADLYSSGDSEKILGEAIKGRRD
RLLISTKATFRVGEDVNAVGSSRHHLIRACEASLKRLQTDHIDVYFMHGFDALTPVEETLRALDDLTRSGKIGYIGASNF
SGWQLMKALATSEKEGLARYVVYQGYYSLIGRHYEWELMPLGLDQGVGLMVWSPLGWGRLTGKIRRGQAASGGRLSTASG
AEGGPTVSDDYLYDVVDALDAVAAETGKTVPQVALNWLLSRPTVCNIVIGARNEEQLKQNLGAVGWSLTPDQIARLDAAS
RENPIYPYWHQIGFDERNPKPTAW
>Mature_344_residues
MEYRQFGRSGLKVPVLSLGTATFGGTDAFFQNWGSTGVAEASRLIDLCLDAGVNFLDTADLYSSGDSEKILGEAIKGRRD
RLLISTKATFRVGEDVNAVGSSRHHLIRACEASLKRLQTDHIDVYFMHGFDALTPVEETLRALDDLTRSGKIGYIGASNF
SGWQLMKALATSEKEGLARYVVYQGYYSLIGRHYEWELMPLGLDQGVGLMVWSPLGWGRLTGKIRRGQAASGGRLSTASG
AEGGPTVSDDYLYDVVDALDAVAAETGKTVPQVALNWLLSRPTVCNIVIGARNEEQLKQNLGAVGWSLTPDQIARLDAAS
RENPIYPYWHQIGFDERNPKPTAW

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=318, Percent_Identity=35.5345911949685, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI4504825, Length=316, Percent_Identity=35.4430379746835, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI27436964, Length=342, Percent_Identity=33.9181286549708, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI27436962, Length=342, Percent_Identity=33.9181286549708, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI27436966, Length=342, Percent_Identity=33.6257309941521, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI27436971, Length=334, Percent_Identity=31.7365269461078, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI223718702, Length=272, Percent_Identity=31.6176470588235, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI41327764, Length=309, Percent_Identity=31.3915857605178, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI41152114, Length=271, Percent_Identity=30.9963099630996, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI223718708, Length=139, Percent_Identity=38.8489208633094, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI87081735, Length=328, Percent_Identity=39.0243902439024, Blast_Score=218, Evalue=5e-58,
Organism=Escherichia coli, GI1789375, Length=327, Percent_Identity=29.9694189602446, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1789199, Length=358, Percent_Identity=30.1675977653631, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1788070, Length=329, Percent_Identity=30.6990881458967, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1788081, Length=277, Percent_Identity=27.7978339350181, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI48994888, Length=292, Percent_Identity=29.1095890410959, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787674, Length=283, Percent_Identity=27.5618374558304, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI212645785, Length=328, Percent_Identity=23.4756097560976, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319958, Length=296, Percent_Identity=31.7567567567568, Blast_Score=147, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6323998, Length=321, Percent_Identity=31.7757009345794, Blast_Score=146, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6325169, Length=340, Percent_Identity=27.3529411764706, Blast_Score=141, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6319951, Length=338, Percent_Identity=28.698224852071, Blast_Score=129, Evalue=6e-31,
Organism=Saccharomyces cerevisiae, GI6322615, Length=251, Percent_Identity=29.0836653386454, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6321052, Length=152, Percent_Identity=32.8947368421053, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24640980, Length=351, Percent_Identity=25.3561253561254, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI45549126, Length=351, Percent_Identity=25.3561253561254, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24646159, Length=235, Percent_Identity=29.7872340425532, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24646155, Length=324, Percent_Identity=26.5432098765432, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37639; Mature: 37639

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYRQFGRSGLKVPVLSLGTATFGGTDAFFQNWGSTGVAEASRLIDLCLDAGVNFLDTAD
CCHHHHCCCCCCEEEEEECCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHCCHH
LYSSGDSEKILGEAIKGRRDRLLISTKATFRVGEDVNAVGSSRHHLIRACEASLKRLQTD
HHCCCCHHHHHHHHHCCCCCEEEEEECCEEEECCCHHHHCCHHHHHHHHHHHHHHHHCCC
HIDVYFMHGFDALTPVEETLRALDDLTRSGKIGYIGASNFSGWQLMKALATSEKEGLARY
CEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCHHHHHHHH
VVYQGYYSLIGRHYEWELMPLGLDQGVGLMVWSPLGWGRLTGKIRRGQAASGGRLSTASG
HHHHHHHHHHCCCCEEEEEEECCCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCEECCCC
AEGGPTVSDDYLYDVVDALDAVAAETGKTVPQVALNWLLSRPTVCNIVIGARNEEQLKQN
CCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHH
LGAVGWSLTPDQIARLDAASRENPIYPYWHQIGFDERNPKPTAW
HCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MEYRQFGRSGLKVPVLSLGTATFGGTDAFFQNWGSTGVAEASRLIDLCLDAGVNFLDTAD
CCHHHHCCCCCCEEEEEECCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHCCHH
LYSSGDSEKILGEAIKGRRDRLLISTKATFRVGEDVNAVGSSRHHLIRACEASLKRLQTD
HHCCCCHHHHHHHHHCCCCCEEEEEECCEEEECCCHHHHCCHHHHHHHHHHHHHHHHCCC
HIDVYFMHGFDALTPVEETLRALDDLTRSGKIGYIGASNFSGWQLMKALATSEKEGLARY
CEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCHHHHHHHH
VVYQGYYSLIGRHYEWELMPLGLDQGVGLMVWSPLGWGRLTGKIRRGQAASGGRLSTASG
HHHHHHHHHHCCCCEEEEEEECCCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCEECCCC
AEGGPTVSDDYLYDVVDALDAVAAETGKTVPQVALNWLLSRPTVCNIVIGARNEEQLKQN
CCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHH
LGAVGWSLTPDQIARLDAASRENPIYPYWHQIGFDERNPKPTAW
HCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]