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The map label for this gene is ydfG [C]

Identifier: 218531842

GI number: 218531842

Start: 4114218

End: 4115138

Strand: Reverse

Name: ydfG [C]

Synonym: Mchl_3918

Alternate gene names: 218531842

Gene position: 4115138-4114218 (Counterclockwise)

Preceding gene: 218531845

Following gene: 218531835

Centisome position: 71.22

GC content: 75.14

Gene sequence:

>921_bases
ATGGCGAGACATCCCTGGACCGCCGCCGACATCCCCTCGCAGGCCGGTCGCCGCGCCGTGGTGACGGGGGCGAGCGCCGG
GCTCGGGTTCGAGACGGCGCGGGCGCTGGCCGGGGCGGGGGCCGCGGTGGTGCTGGCGGTGCGCGATCTCGAGAAGGGGG
AGCGCGCCGCCGCAGCGATCCAGCGGGAGCATCCCGGCGCCGCGCTGTCGCTGCGCCGGATCGACACCGCCTCGCTCGCC
TCCGTCCGCGCCTTCGCGGCGGAGTGGCCGGCGGAGTGGGCGATCGACCGGCTCGTGCTCAATGCCGGCATCGCCGCGGT
GCCCCGGCGCGAGGAGAGCGTGGACGGGTTCGAGCGGCAACTCGCCACGAACTATCTCGGGCATTTCGCGCTGACCGGGC
TGCTGCGGCCGGCCCTGAGCCCCTCAGCGCGGGTGGTGTCGGTGTCGAGCGTCGCCCATCGCAGCGGTCGGATCCGGTTC
GACGACCTGCACTGGCGCGAGATCTACGGGGCGCAACGCGCCTACCGGCAGAGCAAGCTCGCGCTGCTGATGTTCGCCCT
CGAACTCGACCAGAGGCTGAAGGCGGCGGGATCGGGCATCGCCTCGCTCGCGGCGCATCCGGGGCTCGCCCGCACCGAGG
TGTTCCGCCGGGGCGACCGGGCCGGCGCGTTCCAGCAGGGAGCGGGACGGGCGATCTTCTCGCTGATCGGCCAGCCGGCG
GCGCAAGGCGCCCTGCCGATCCTCTACGCGGCCACCGCGCCGGAGGCGGAGCGCGGCGGCTATTACGGACCGGACGGCGT
CTGGGAGGCCCGCGGCTACCCGAAGCCCGCCGCGATCGCGTCCCAAGCTCTCGACCGCGCGGCAGCCGGGCGGCTCTGGG
CGGTCTCGGAGACCCTCACCGGCGTGCGGTTCGCGCTGTGA

Upstream 100 bases:

>100_bases
CGTCTTGTTCGGGGATCACGCCGCCCATTACGGAGCCCGCGCGCGATCGGTTTCGCGCGACCGGTCTTTTTTCGACTCGA
AGCGTGAGGAGCGCCGCTCG

Downstream 100 bases:

>100_bases
GAGACGGTTCGGTGTACCCCGAAGCCGACAAGCCGGTCACGCAACCGATCGCTCTTCATTTCGCGATGTTCGCAGAACCG
CGCTGACAGAAACGGCTCCG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MARHPWTAADIPSQAGRRAVVTGASAGLGFETARALAGAGAAVVLAVRDLEKGERAAAAIQREHPGAALSLRRIDTASLA
SVRAFAAEWPAEWAIDRLVLNAGIAAVPRREESVDGFERQLATNYLGHFALTGLLRPALSPSARVVSVSSVAHRSGRIRF
DDLHWREIYGAQRAYRQSKLALLMFALELDQRLKAAGSGIASLAAHPGLARTEVFRRGDRAGAFQQGAGRAIFSLIGQPA
AQGALPILYAATAPEAERGGYYGPDGVWEARGYPKPAAIASQALDRAAAGRLWAVSETLTGVRFAL

Sequences:

>Translated_306_residues
MARHPWTAADIPSQAGRRAVVTGASAGLGFETARALAGAGAAVVLAVRDLEKGERAAAAIQREHPGAALSLRRIDTASLA
SVRAFAAEWPAEWAIDRLVLNAGIAAVPRREESVDGFERQLATNYLGHFALTGLLRPALSPSARVVSVSSVAHRSGRIRF
DDLHWREIYGAQRAYRQSKLALLMFALELDQRLKAAGSGIASLAAHPGLARTEVFRRGDRAGAFQQGAGRAIFSLIGQPA
AQGALPILYAATAPEAERGGYYGPDGVWEARGYPKPAAIASQALDRAAAGRLWAVSETLTGVRFAL
>Mature_305_residues
ARHPWTAADIPSQAGRRAVVTGASAGLGFETARALAGAGAAVVLAVRDLEKGERAAAAIQREHPGAALSLRRIDTASLAS
VRAFAAEWPAEWAIDRLVLNAGIAAVPRREESVDGFERQLATNYLGHFALTGLLRPALSPSARVVSVSSVAHRSGRIRFD
DLHWREIYGAQRAYRQSKLALLMFALELDQRLKAAGSGIASLAAHPGLARTEVFRRGDRAGAFQQGAGRAIFSLIGQPAA
QGALPILYAATAPEAERGGYYGPDGVWEARGYPKPAAIASQALDRAAAGRLWAVSETLTGVRFAL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI225579078, Length=305, Percent_Identity=41.6393442622951, Blast_Score=168, Evalue=7e-42,
Organism=Homo sapiens, GI186928839, Length=301, Percent_Identity=38.2059800664452, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI166795268, Length=292, Percent_Identity=38.6986301369863, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI10190746, Length=309, Percent_Identity=35.2750809061489, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI193804850, Length=300, Percent_Identity=32.6666666666667, Blast_Score=138, Evalue=6e-33,
Organism=Homo sapiens, GI19923931, Length=259, Percent_Identity=41.3127413127413, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI7706523, Length=305, Percent_Identity=34.4262295081967, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI146231950, Length=298, Percent_Identity=37.5838926174497, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17532791, Length=309, Percent_Identity=29.4498381877023, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17558006, Length=211, Percent_Identity=36.4928909952607, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71992402, Length=308, Percent_Identity=29.8701298701299, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI193207620, Length=307, Percent_Identity=30.9446254071661, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17532805, Length=302, Percent_Identity=30.794701986755, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17535059, Length=276, Percent_Identity=28.9855072463768, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI32565532, Length=208, Percent_Identity=32.6923076923077, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17505416, Length=311, Percent_Identity=25.7234726688103, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI72001364, Length=300, Percent_Identity=29.3333333333333, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324820, Length=327, Percent_Identity=29.0519877675841, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6324148, Length=281, Percent_Identity=25.2669039145907, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28573296, Length=296, Percent_Identity=39.1891891891892, Blast_Score=159, Evalue=2e-39,
Organism=Drosophila melanogaster, GI22024069, Length=299, Percent_Identity=38.1270903010033, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24586328, Length=293, Percent_Identity=37.542662116041, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI19921754, Length=296, Percent_Identity=35.8108108108108, Blast_Score=143, Evalue=1e-34,
Organism=Drosophila melanogaster, GI161076371, Length=258, Percent_Identity=39.5348837209302, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI45554248, Length=262, Percent_Identity=38.5496183206107, Blast_Score=131, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24640117, Length=262, Percent_Identity=38.5496183206107, Blast_Score=131, Evalue=5e-31,
Organism=Drosophila melanogaster, GI20129347, Length=298, Percent_Identity=32.8859060402685, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24647946, Length=282, Percent_Identity=32.9787234042553, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI45553409, Length=282, Percent_Identity=32.9787234042553, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24647948, Length=282, Percent_Identity=32.9787234042553, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24656154, Length=264, Percent_Identity=32.9545454545455, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI19922628, Length=264, Percent_Identity=32.9545454545455, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24647931, Length=273, Percent_Identity=36.6300366300366, Blast_Score=108, Evalue=5e-24,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 32363; Mature: 32232

Theoretical pI: Translated: 10.89; Mature: 10.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARHPWTAADIPSQAGRRAVVTGASAGLGFETARALAGAGAAVVLAVRDLEKGERAAAAI
CCCCCCCCCCCCHHCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEEEHHHHCCHHHHHHH
QREHPGAALSLRRIDTASLASVRAFAAEWPAEWAIDRLVLNAGIAAVPRREESVDGFERQ
HHCCCCCEEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHCCCCHHHHHHHHHH
LATNYLGHFALTGLLRPALSPSARVVSVSSVAHRSGRIRFDDLHWREIYGAQRAYRQSKL
HHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHH
ALLMFALELDQRLKAAGSGIASLAAHPGLARTEVFRRGDRAGAFQQGAGRAIFSLIGQPA
HHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHCCCCCCCHHHCCHHHHHHHHCCCC
AQGALPILYAATAPEAERGGYYGPDGVWEARGYPKPAAIASQALDRAAAGRLWAVSETLT
CCCCCEEEEEECCCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEHHHHHC
GVRFAL
CHHHCC
>Mature Secondary Structure 
ARHPWTAADIPSQAGRRAVVTGASAGLGFETARALAGAGAAVVLAVRDLEKGERAAAAI
CCCCCCCCCCCHHCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEEEHHHHCCHHHHHHH
QREHPGAALSLRRIDTASLASVRAFAAEWPAEWAIDRLVLNAGIAAVPRREESVDGFERQ
HHCCCCCEEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHCCCCHHHHHHHHHH
LATNYLGHFALTGLLRPALSPSARVVSVSSVAHRSGRIRFDDLHWREIYGAQRAYRQSKL
HHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHH
ALLMFALELDQRLKAAGSGIASLAAHPGLARTEVFRRGDRAGAFQQGAGRAIFSLIGQPA
HHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHCCCCCCCHHHCCHHHHHHHHCCCC
AQGALPILYAATAPEAERGGYYGPDGVWEARGYPKPAAIASQALDRAAAGRLWAVSETLT
CCCCCEEEEEECCCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEHHHHHC
GVRFAL
CHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383668 [H]