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The map label for this gene is yfgC [H]

Identifier: 218531558

GI number: 218531558

Start: 3819344

End: 3820846

Strand: Reverse

Name: yfgC [H]

Synonym: Mchl_3626

Alternate gene names: 218531558

Gene position: 3820846-3819344 (Counterclockwise)

Preceding gene: 218531559

Following gene: 218531557

Centisome position: 66.13

GC content: 72.99

Gene sequence:

>1503_bases
ATGACGGGGGATCGGCAGCATCAATCGGGGCGGCGGCGCGTGCGCGGGGGCGGTCGTCGGAGACTTGCACGGCTCGGCAC
GCTGGCCGCGCTCGCGGGCCTGCTCGCGGCCTGCGCCGCCGACCAGACCGGAAGCGTCTTGACGCCGGCGGTCATCACGG
TGCCCGAGCAGGCACCGAAGACCACGGGGCGCACACGCTCCGACGAGGCGGACCACGCCAAGCTCGTGGCCTCGTTCGGC
GGCGAGTACCGCGCGCCCGCCGCCCACCGGCTCATCACCGAGATCACCGACCGGCTGGTGCGCGCCAGCGACCGGCCGGA
GGAGAGCTACGCGGTCACGCTGCTCGATTCGCCGGTCGTCAACGCCTTCGCCCTGCCGAGCGGCCGGCTCTACGTGACCC
GCGGCCTGCTGGCGCTCGCCGGCGACAGCTCGGAGGTCGCGGCGGTGCTCGCGCACGAGATCGCCCACGTGACGTTGCGC
CATGCCACGGCCCGCAGCGAGATGGCCCTGCGCTCGCAGCTCGTCAGCCGCGTGGTCGCCGACGTGCTGAACGACCCCGT
CACGGGGGCGCAGCTCGAGAGCCAGTCCAAGTTCACCCTCGCCCGCTTCTCCCGCGAGCAGGAGCTGGAAGCGGACACGA
ACGGCGTGCGCGTGCTGGCCCAGGCTGGCTACGACCCGTTCGGTGCCGGCCGTTTCCTCGATGCGCTCCAGCGCACTATG
GCGCTCAAGGCCGGCAACGGCAGCGCGGCCGAGCCCGACATGCTCGCGACCCACCCCGCCACCGCCGAGCGCATCGCGCT
GGTCACCCGCGCGGCCCGGCGCATCGGCGCCCCCGGCCTCGGCGCCGACGATCGCGCCCGCTATCTCACGGCGATCGACG
GGCTCGCCTATGGCGACAATCCCGGCGAGGGACTGGTGCGCGGTCGCCGCTTCCTGCATCCGGGCTTGAGCATCGCCTTC
GAGGTGCCGGACGCCTTCGCCATCGAGAACACCCGCAACGCCGTGCTCGGCACCACGCCGGAGGGCAGCCGCCGCCTGCT
GTTCGATCAGGTCGAGGCGAGCGGCGACCGCAGCCTGGAAGACGTGCTGCGCGCGACCTGGAACGATGCCATCGAGGCGG
GCTCGGTCGAGAACCGCATCGTCGGCGGTCGCTCGGTCGCCACCGCCCTGTCGCGGGGCAAGGACTGGACCTTCCGCCTC
GCGGCGATCCGCATGGGCGAGACCACCTACCGCATGATCATGGCGGCCAAGGGCGCGACCGACCCCGAGCCGGCCTTCCG
CCGCTGGCTGGAGAGCCTGCGCCCGATCGAGCCGGAGGAGACCGCCTCGCTCAAGCCGGCGCATCTGCGGATCGTCACCG
CCGCTCCGGGCGACACCGTGGAGGGGTTGGCCCGCCGCATGAGCGTGCCCGACCGCGCCGTGGATCGCTTCCTCGTGCTC
AACAGCCTGCAGCGCGGCGCGGTGGTGAAACCCGGCCTGAGCTACAAGCTCGTCGTCGAGTGA

Upstream 100 bases:

>100_bases
CGGCATGGTCGAGATCGGTCGGGGACCGTTCATCGATCTCGCCGGTGTCGACGGCATCGAGGTCATCGAGGGAGAGCGGG
CGCTGCGGCGCTAGAACGGC

Downstream 100 bases:

>100_bases
GGGGCGAGGCCGTCGGGCTTGCACGTCCGAGGGCCGGCGCTTAGGCCGATGCCTCGACGCAACGGGTCCGACGTGACGTC
CTCCGAGCTTCCCACCGATA

Product: peptidase M48 Ste24p

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 499

Protein sequence:

>500_residues
MTGDRQHQSGRRRVRGGGRRRLARLGTLAALAGLLAACAADQTGSVLTPAVITVPEQAPKTTGRTRSDEADHAKLVASFG
GEYRAPAAHRLITEITDRLVRASDRPEESYAVTLLDSPVVNAFALPSGRLYVTRGLLALAGDSSEVAAVLAHEIAHVTLR
HATARSEMALRSQLVSRVVADVLNDPVTGAQLESQSKFTLARFSREQELEADTNGVRVLAQAGYDPFGAGRFLDALQRTM
ALKAGNGSAAEPDMLATHPATAERIALVTRAARRIGAPGLGADDRARYLTAIDGLAYGDNPGEGLVRGRRFLHPGLSIAF
EVPDAFAIENTRNAVLGTTPEGSRRLLFDQVEASGDRSLEDVLRATWNDAIEAGSVENRIVGGRSVATALSRGKDWTFRL
AAIRMGETTYRMIMAAKGATDPEPAFRRWLESLRPIEPEETASLKPAHLRIVTAAPGDTVEGLARRMSVPDRAVDRFLVL
NSLQRGAVVKPGLSYKLVVE

Sequences:

>Translated_500_residues
MTGDRQHQSGRRRVRGGGRRRLARLGTLAALAGLLAACAADQTGSVLTPAVITVPEQAPKTTGRTRSDEADHAKLVASFG
GEYRAPAAHRLITEITDRLVRASDRPEESYAVTLLDSPVVNAFALPSGRLYVTRGLLALAGDSSEVAAVLAHEIAHVTLR
HATARSEMALRSQLVSRVVADVLNDPVTGAQLESQSKFTLARFSREQELEADTNGVRVLAQAGYDPFGAGRFLDALQRTM
ALKAGNGSAAEPDMLATHPATAERIALVTRAARRIGAPGLGADDRARYLTAIDGLAYGDNPGEGLVRGRRFLHPGLSIAF
EVPDAFAIENTRNAVLGTTPEGSRRLLFDQVEASGDRSLEDVLRATWNDAIEAGSVENRIVGGRSVATALSRGKDWTFRL
AAIRMGETTYRMIMAAKGATDPEPAFRRWLESLRPIEPEETASLKPAHLRIVTAAPGDTVEGLARRMSVPDRAVDRFLVL
NSLQRGAVVKPGLSYKLVVE
>Mature_499_residues
TGDRQHQSGRRRVRGGGRRRLARLGTLAALAGLLAACAADQTGSVLTPAVITVPEQAPKTTGRTRSDEADHAKLVASFGG
EYRAPAAHRLITEITDRLVRASDRPEESYAVTLLDSPVVNAFALPSGRLYVTRGLLALAGDSSEVAAVLAHEIAHVTLRH
ATARSEMALRSQLVSRVVADVLNDPVTGAQLESQSKFTLARFSREQELEADTNGVRVLAQAGYDPFGAGRFLDALQRTMA
LKAGNGSAAEPDMLATHPATAERIALVTRAARRIGAPGLGADDRARYLTAIDGLAYGDNPGEGLVRGRRFLHPGLSIAFE
VPDAFAIENTRNAVLGTTPEGSRRLLFDQVEASGDRSLEDVLRATWNDAIEAGSVENRIVGGRSVATALSRGKDWTFRLA
AIRMGETTYRMIMAAKGATDPEPAFRRWLESLRPIEPEETASLKPAHLRIVTAAPGDTVEGLARRMSVPDRAVDRFLVLN
SLQRGAVVKPGLSYKLVVE

Specific function: Unknown

COG id: COG4784

COG function: function code R; Putative Zn-dependent protease

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI21686999, Length=192, Percent_Identity=28.125, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1788840, Length=190, Percent_Identity=28.9473684210526, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082185, Length=238, Percent_Identity=31.9327731092437, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001915
- InterPro:   IPR011990 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: NA

Molecular weight: Translated: 53640; Mature: 53508

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGDRQHQSGRRRVRGGGRRRLARLGTLAALAGLLAACAADQTGSVLTPAVITVPEQAPK
CCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCC
TTGRTRSDEADHAKLVASFGGEYRAPAAHRLITEITDRLVRASDRPEESYAVTLLDSPVV
CCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCC
NAFALPSGRLYVTRGLLALAGDSSEVAAVLAHEIAHVTLRHATARSEMALRSQLVSRVVA
CEEECCCCCEEEEECEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVLNDPVTGAQLESQSKFTLARFSREQELEADTNGVRVLAQAGYDPFGAGRFLDALQRTM
HHHCCCCCCCCCCCCCCHHHHHHCCHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHH
ALKAGNGSAAEPDMLATHPATAERIALVTRAARRIGAPGLGADDRARYLTAIDGLAYGDN
HEECCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCC
PGEGLVRGRRFLHPGLSIAFEVPDAFAIENTRNAVLGTTPEGSRRLLFDQVEASGDRSLE
CCHHHHHHHHHHCCCCEEEEECCCCEEECCCCCCEEECCCCCCCHHHHHHHHCCCCCCHH
DVLRATWNDAIEAGSVENRIVGGRSVATALSRGKDWTFRLAAIRMGETTYRMIMAAKGAT
HHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHCCCCCEEEEEEEEECCHHEEHHEEECCCC
DPEPAFRRWLESLRPIEPEETASLKPAHLRIVTAAPGDTVEGLARRMSVPDRAVDRFLVL
CCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHH
NSLQRGAVVKPGLSYKLVVE
HHHCCCCEECCCCCEEEEEC
>Mature Secondary Structure 
TGDRQHQSGRRRVRGGGRRRLARLGTLAALAGLLAACAADQTGSVLTPAVITVPEQAPK
CCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCC
TTGRTRSDEADHAKLVASFGGEYRAPAAHRLITEITDRLVRASDRPEESYAVTLLDSPVV
CCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCC
NAFALPSGRLYVTRGLLALAGDSSEVAAVLAHEIAHVTLRHATARSEMALRSQLVSRVVA
CEEECCCCCEEEEECEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVLNDPVTGAQLESQSKFTLARFSREQELEADTNGVRVLAQAGYDPFGAGRFLDALQRTM
HHHCCCCCCCCCCCCCCHHHHHHCCHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHH
ALKAGNGSAAEPDMLATHPATAERIALVTRAARRIGAPGLGADDRARYLTAIDGLAYGDN
HEECCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCC
PGEGLVRGRRFLHPGLSIAFEVPDAFAIENTRNAVLGTTPEGSRRLLFDQVEASGDRSLE
CCHHHHHHHHHHCCCCEEEEECCCCEEECCCCCCEEECCCCCCCHHHHHHHHCCCCCCHH
DVLRATWNDAIEAGSVENRIVGGRSVATALSRGKDWTFRLAAIRMGETTYRMIMAAKGAT
HHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHCCCCCEEEEEEEEECCHHEEHHEEECCCC
DPEPAFRRWLESLRPIEPEETASLKPAHLRIVTAAPGDTVEGLARRMSVPDRAVDRFLVL
CCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHH
NSLQRGAVVKPGLSYKLVVE
HHHCCCCEECCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]