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The map label for this gene is murI [H]

Identifier: 218531473

GI number: 218531473

Start: 3724602

End: 3725462

Strand: Reverse

Name: murI [H]

Synonym: Mchl_3541

Alternate gene names: 218531473

Gene position: 3725462-3724602 (Counterclockwise)

Preceding gene: 218531477

Following gene: 218531471

Centisome position: 64.48

GC content: 71.89

Gene sequence:

>861_bases
ATGGCAGGGGCGACCCTTTCGGCGGCATTGCCGGCCCAGAATTCTCAGCCGGTCATTCTCGTCTTCGATTCCGGCCTCGG
TGGTCTCACCGTGCTGGAGCAGGTGCGCCGCGCCCGGCCGGACGCGGCTTATGTCTACGCCGCCGACGATGCGGCCTTCC
CCTACGGCGCCCTGACCGAGGAAAGGCTCGTGGCGCGGGTGATCGCGGTGATGGAGCGGCTGCTGCTGCGTCACGCCCCC
GACCTCGTGGTGATCGCCTGCAACACCGCATCGACCCTGGTGCTGCCGGCCCTGCGCCAGCGCTTTGTCACGCCCTTCGT
CGGCGTGGTCCCCCCGATCAAGCCGGCCGCTGCGCTGACGCGGACCCGCCTGATCTCCCTGCTCGCCACCCCCGGCACCG
TGGCGCGGGCCTATACCCACGATCTCGTGGCGAACTTCGCGGGCGATTGCGCCGTGACGCTGGTGGGCTCCAAGAACCTC
GCGGGCTACGCCGAGGCTGAGATGGCCGGTGAGCCGGTCTCGGACGCGGCGATCCTGGCCGAGATCGCGCCCTGTTTCGT
CGAGGGAGCGGACGGCGCGTGCACCGATGTGGTCTGCCTCTCCTGCACCCACTACCCGCTGCTGCTGCCCCGTTTCGAGC
GCCTCGCCCCCTGGCCGGTCACCTGGATCGACCCGGCCCCGGCCATCGCCCGCCGGGTGATCCAGCTTCTCGGCGAGATG
CCCGCGCACGCGCTCGACGCGCCGCCCGCCTGCGCCGTGTTCACCGGCGGGGCCGGGCTCAACCCGGCGCTCGGCCGCTC
GCTGGAGCGGCGGGGCCTGTCCGAGACGGTGATCGAGGCGATGCCGCTGACGCTGTGCTGA

Upstream 100 bases:

>100_bases
AGCCGCAGTGAGGTGTCCTTAACCGTCGCCGACGGACACTCGTTGCCCCACGGTTTCCACGGATGCGCGAGCCCGGGCGG
CGGTCATGCGGATCGATCTG

Downstream 100 bases:

>100_bases
GACGGGCCATCAGCGCCTCTCCCACGCCGCCAGTTCCTCCGGCACCAGCGTCGCCGCATCCTGCCGGGCGATGATCTCCG
CGAGATCGACCGGCGAGAAA

Product: glutamate racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MAGATLSAALPAQNSQPVILVFDSGLGGLTVLEQVRRARPDAAYVYAADDAAFPYGALTEERLVARVIAVMERLLLRHAP
DLVVIACNTASTLVLPALRQRFVTPFVGVVPPIKPAAALTRTRLISLLATPGTVARAYTHDLVANFAGDCAVTLVGSKNL
AGYAEAEMAGEPVSDAAILAEIAPCFVEGADGACTDVVCLSCTHYPLLLPRFERLAPWPVTWIDPAPAIARRVIQLLGEM
PAHALDAPPACAVFTGGAGLNPALGRSLERRGLSETVIEAMPLTLC

Sequences:

>Translated_286_residues
MAGATLSAALPAQNSQPVILVFDSGLGGLTVLEQVRRARPDAAYVYAADDAAFPYGALTEERLVARVIAVMERLLLRHAP
DLVVIACNTASTLVLPALRQRFVTPFVGVVPPIKPAAALTRTRLISLLATPGTVARAYTHDLVANFAGDCAVTLVGSKNL
AGYAEAEMAGEPVSDAAILAEIAPCFVEGADGACTDVVCLSCTHYPLLLPRFERLAPWPVTWIDPAPAIARRVIQLLGEM
PAHALDAPPACAVFTGGAGLNPALGRSLERRGLSETVIEAMPLTLC
>Mature_285_residues
AGATLSAALPAQNSQPVILVFDSGLGGLTVLEQVRRARPDAAYVYAADDAAFPYGALTEERLVARVIAVMERLLLRHAPD
LVVIACNTASTLVLPALRQRFVTPFVGVVPPIKPAAALTRTRLISLLATPGTVARAYTHDLVANFAGDCAVTLVGSKNLA
GYAEAEMAGEPVSDAAILAEIAPCFVEGADGACTDVVCLSCTHYPLLLPRFERLAPWPVTWIDPAPAIARRVIQLLGEMP
AHALDAPPACAVFTGGAGLNPALGRSLERRGLSETVIEAMPLTLC

Specific function: Provides the (R)-glutamate required for cell wall biosynthesis [H]

COG id: COG0796

COG function: function code M; Glutamate racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate/glutamate racemases family [H]

Homologues:

Organism=Escherichia coli, GI87082355, Length=263, Percent_Identity=45.2471482889734, Blast_Score=185, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015942
- InterPro:   IPR001920
- InterPro:   IPR018187
- InterPro:   IPR004391 [H]

Pfam domain/function: PF01177 Asp_Glu_race [H]

EC number: =5.1.1.3 [H]

Molecular weight: Translated: 29968; Mature: 29837

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00923 ASP_GLU_RACEMASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGATLSAALPAQNSQPVILVFDSGLGGLTVLEQVRRARPDAAYVYAADDAAFPYGALTE
CCCCCCEEECCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHH
ERLVARVIAVMERLLLRHAPDLVVIACNTASTLVLPALRQRFVTPFVGVVPPIKPAAALT
HHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCHHHHCCCCCCHHHHHH
RTRLISLLATPGTVARAYTHDLVANFAGDCAVTLVGSKNLAGYAEAEMAGEPVSDAAILA
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHCCCCCHHHHHHH
EIAPCFVEGADGACTDVVCLSCTHYPLLLPRFERLAPWPVTWIDPAPAIARRVIQLLGEM
HHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHC
PAHALDAPPACAVFTGGAGLNPALGRSLERRGLSETVIEAMPLTLC
CHHHCCCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHCCCCCC
>Mature Secondary Structure 
AGATLSAALPAQNSQPVILVFDSGLGGLTVLEQVRRARPDAAYVYAADDAAFPYGALTE
CCCCCEEECCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHH
ERLVARVIAVMERLLLRHAPDLVVIACNTASTLVLPALRQRFVTPFVGVVPPIKPAAALT
HHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCHHHHCCCCCCHHHHHH
RTRLISLLATPGTVARAYTHDLVANFAGDCAVTLVGSKNLAGYAEAEMAGEPVSDAAILA
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHCCCCCHHHHHHH
EIAPCFVEGADGACTDVVCLSCTHYPLLLPRFERLAPWPVTWIDPAPAIARRVIQLLGEM
HHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHC
PAHALDAPPACAVFTGGAGLNPALGRSLERRGLSETVIEAMPLTLC
CHHHCCCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]