Click here to switch to the map view.

The map label for this gene is yogA [H]

Identifier: 218531402

GI number: 218531402

Start: 3654014

End: 3655027

Strand: Reverse

Name: yogA [H]

Synonym: Mchl_3470

Alternate gene names: 218531402

Gene position: 3655027-3654014 (Counterclockwise)

Preceding gene: 218531403

Following gene: 218531401

Centisome position: 63.26

GC content: 70.22

Gene sequence:

>1014_bases
ATGCGCGCCTACGAGATGTCCGCCGCCGCCGGCCTCGACAGTTGGAAGAGTGCCGAGCGCCCGACGCCCGAACCGGGCCG
CGGGCAGGTTCTGGTGCGGATGCGCGCCGCCTCCCTCAACTACCGCGATCTGCTGATCTGCCAGGGCCGCTACCCGTTCG
CGGTCAATCTCGACCGACTGATCCCGCTCTCGGACGGGGCGGGTGAGATCGTGGCGATCGGCCCCGGCGTGCGCCGCTTC
TCCGGCGGTGAGCGGGTCGCCGGGATTTTCTCGCAGAGCTGGCTCGGCGGCGCGCAGGTGGCCGATACGTGGCAGACCGC
GCTCGGCGGCGCCATCGACGGGGTGCTGACCGAGTATCAGGTGTTCGACGAGGACGGGCTGGTCACGCTGCCCGATCATC
TCAGCTTCGAGGAAGGGGCGACGCTGCCCTGCGCAGCGGTGACCGCCTGGAACGCACTCTACGGGCTCAAGCCCCTTCGG
GCCGGCGAGACGGTGCTGACGCTCGGCACCGGCGGCGTCTCGATCTTCGCGATCCAGCTCGCCCACGCGGCCGGGGCGCG
GGTCATCGCCACCTCGTCGAGCGATGCCAAGCTGGAGAAGGCCCGCGCGCTCGGCGCGCACGACACCATCAACTACCGCA
CCCATCCCGATTGGGAGGGCGAGGTGCGCCGGCTGACCGGTGGAACCGGCGTCGATCACGTCGTCGAGGTCGGCGGCACC
GGGACGCTCCCGCGCTCCATCGCCTCGACCCGGCCCGGTGGGCATATCGGCTTGATCGGCCTGCTGGCTCAGGGCGAGGC
GTTCGACCCGCTGGCGATCCTCGGCGCGAGCTGCATCGTGCGCGGCGTCGCCGTCGGCCCACGAGAGATGTTCGAGGACA
TGAACCGCTCGATCGCCCTGCACGGGATCAAGCCGGTGATCGACCGGGTCTACGGATTCGACGAGGCACCGGCGGCTCTC
AAAGCCTTGGCCGAGGCCGGGCATGTCGGCAAGATCGTGATCCGGATCGATTGA

Upstream 100 bases:

>100_bases
CGTGAGGAAGAGGTCGCCTTCGGGCGGCCTCTTCCCATATGCGCCTGCCATGAGTGCCCGCGTCGAACCCAAGACGCGAG
AAACCCCACGGGAGACCGCC

Downstream 100 bases:

>100_bases
TGCTCGGGCGTCGGGGGAAGAGGCGGGTGATGCGCGCAGGGGTCGGATGGGGACTTCTCGCAGCGCTCGTGTCGCCGGTG
GCGGCGAGCGCCGCGGACGT

Product: alcohol dehydrogenase zinc-binding domain protein

Products: aldehyde; ketone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MRAYEMSAAAGLDSWKSAERPTPEPGRGQVLVRMRAASLNYRDLLICQGRYPFAVNLDRLIPLSDGAGEIVAIGPGVRRF
SGGERVAGIFSQSWLGGAQVADTWQTALGGAIDGVLTEYQVFDEDGLVTLPDHLSFEEGATLPCAAVTAWNALYGLKPLR
AGETVLTLGTGGVSIFAIQLAHAAGARVIATSSSDAKLEKARALGAHDTINYRTHPDWEGEVRRLTGGTGVDHVVEVGGT
GTLPRSIASTRPGGHIGLIGLLAQGEAFDPLAILGASCIVRGVAVGPREMFEDMNRSIALHGIKPVIDRVYGFDEAPAAL
KALAEAGHVGKIVIRID

Sequences:

>Translated_337_residues
MRAYEMSAAAGLDSWKSAERPTPEPGRGQVLVRMRAASLNYRDLLICQGRYPFAVNLDRLIPLSDGAGEIVAIGPGVRRF
SGGERVAGIFSQSWLGGAQVADTWQTALGGAIDGVLTEYQVFDEDGLVTLPDHLSFEEGATLPCAAVTAWNALYGLKPLR
AGETVLTLGTGGVSIFAIQLAHAAGARVIATSSSDAKLEKARALGAHDTINYRTHPDWEGEVRRLTGGTGVDHVVEVGGT
GTLPRSIASTRPGGHIGLIGLLAQGEAFDPLAILGASCIVRGVAVGPREMFEDMNRSIALHGIKPVIDRVYGFDEAPAAL
KALAEAGHVGKIVIRID
>Mature_337_residues
MRAYEMSAAAGLDSWKSAERPTPEPGRGQVLVRMRAASLNYRDLLICQGRYPFAVNLDRLIPLSDGAGEIVAIGPGVRRF
SGGERVAGIFSQSWLGGAQVADTWQTALGGAIDGVLTEYQVFDEDGLVTLPDHLSFEEGATLPCAAVTAWNALYGLKPLR
AGETVLTLGTGGVSIFAIQLAHAAGARVIATSSSDAKLEKARALGAHDTINYRTHPDWEGEVRRLTGGTGVDHVVEVGGT
GTLPRSIASTRPGGHIGLIGLLAQGEAFDPLAILGASCIVRGVAVGPREMFEDMNRSIALHGIKPVIDRVYGFDEAPAAL
KALAEAGHVGKIVIRID

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=355, Percent_Identity=26.7605633802817, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI22538444, Length=355, Percent_Identity=26.7605633802817, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI18379349, Length=337, Percent_Identity=27.0029673590504, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI194239674, Length=343, Percent_Identity=25.6559766763848, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI13236495, Length=343, Percent_Identity=25.6559766763848, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI24308257, Length=372, Percent_Identity=22.8494623655914, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI194239676, Length=215, Percent_Identity=29.7674418604651, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI28557745, Length=255, Percent_Identity=29.8039215686275, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI47519420, Length=352, Percent_Identity=26.9886363636364, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI87082125, Length=213, Percent_Identity=31.4553990610329, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1790045, Length=335, Percent_Identity=25.0746268656716, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790485, Length=249, Percent_Identity=26.5060240963855, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17507255, Length=345, Percent_Identity=26.0869565217391, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562876, Length=269, Percent_Identity=27.1375464684015, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562878, Length=210, Percent_Identity=27.6190476190476, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17562584, Length=320, Percent_Identity=23.75, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17556000, Length=271, Percent_Identity=28.0442804428044, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71988145, Length=202, Percent_Identity=25.7425742574257, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319955, Length=291, Percent_Identity=28.8659793814433, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322619, Length=291, Percent_Identity=28.8659793814433, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6319621, Length=334, Percent_Identity=26.0479041916168, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6323729, Length=335, Percent_Identity=25.0746268656716, Blast_Score=72, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6324486, Length=327, Percent_Identity=24.7706422018349, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323961, Length=256, Percent_Identity=27.34375, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323099, Length=321, Percent_Identity=27.4143302180685, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.1

Molecular weight: Translated: 35425; Mature: 35425

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAYEMSAAAGLDSWKSAERPTPEPGRGQVLVRMRAASLNYRDLLICQGRYPFAVNLDRL
CCCCCCHHHCCCCHHHCCCCCCCCCCCCEEEEEEEECCCCCCEEEEECCCCCEEEEHHHE
IPLSDGAGEIVAIGPGVRRFSGGERVAGIFSQSWLGGAQVADTWQTALGGAIDGVLTEYQ
EECCCCCCCEEEECCCCHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHEE
VFDEDGLVTLPDHLSFEEGATLPCAAVTAWNALYGLKPLRAGETVLTLGTGGVSIFAIQL
EECCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEEEEEE
AHAAGARVIATSSSDAKLEKARALGAHDTINYRTHPDWEGEVRRLTGGTGVDHVVEVGGT
HHCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEECCC
GTLPRSIASTRPGGHIGLIGLLAQGEAFDPLAILGASCIVRGVAVGPREMFEDMNRSIAL
CCCCHHHHCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEE
HGIKPVIDRVYGFDEAPAALKALAEAGHVGKIVIRID
CCCHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEEEC
>Mature Secondary Structure
MRAYEMSAAAGLDSWKSAERPTPEPGRGQVLVRMRAASLNYRDLLICQGRYPFAVNLDRL
CCCCCCHHHCCCCHHHCCCCCCCCCCCCEEEEEEEECCCCCCEEEEECCCCCEEEEHHHE
IPLSDGAGEIVAIGPGVRRFSGGERVAGIFSQSWLGGAQVADTWQTALGGAIDGVLTEYQ
EECCCCCCCEEEECCCCHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHEE
VFDEDGLVTLPDHLSFEEGATLPCAAVTAWNALYGLKPLRAGETVLTLGTGGVSIFAIQL
EECCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEEEEEE
AHAAGARVIATSSSDAKLEKARALGAHDTINYRTHPDWEGEVRRLTGGTGVDHVVEVGGT
HHCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEECCC
GTLPRSIASTRPGGHIGLIGLLAQGEAFDPLAILGASCIVRGVAVGPREMFEDMNRSIAL
CCCCHHHHCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEE
HGIKPVIDRVYGFDEAPAALKALAEAGHVGKIVIRID
CCCHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alcohol; NAD+

Specific reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]