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The map label for this gene is ltaE [H]

Identifier: 218531374

GI number: 218531374

Start: 3629230

End: 3630270

Strand: Reverse

Name: ltaE [H]

Synonym: Mchl_3442

Alternate gene names: 218531374

Gene position: 3630270-3629230 (Counterclockwise)

Preceding gene: 218531375

Following gene: 218531372

Centisome position: 62.83

GC content: 68.2

Gene sequence:

>1041_bases
GTGGCCGAACAGCAATTCGCCAGCGACAACTATGCCGGGATCTGCCCGGAGGCCCTCACCGCGATGCAGGCGGCCAATGC
CGGCCACGCCCCCGCCTACGGCGCCGATACCTGGACGCAGGCCGCGGCTGACGGCTTCCGGCGGTTGTTCGAGACCGATT
GCGAGGTGTTCTTCGTCTTCAACGGCACCGCCGCCAACTCGCTGGCGCTGGCCTCGCTCTGCCAATCCTATCACAGCGTG
ATCTGTGCGGACTCGGCGCATATCGAGACCGACGAATGCGGTGCGCCGGAATTCTTCTCAAACGGCTCGAAGCTGCTCAC
CGCCGCGACCGATGACGGGAAGCTCACGCCCGAGATCGTGCGGACGATCGCCGGTAAGCGCTCCGACATCCATTTCCCGA
AACCGCGGGCGGTGACGCTGACCCAGGCGACGGAGACGGGGCGGGTCTACAGCCTCGACGAGATCGCGGCCATCTCGGCC
GTTTGCCGCGCTTTGGGCCTGCGCCTGCACATGGACGGCGCCCGCTTTGCCAATGCCTGCGCCTCGCTCGACGCCTCCCC
GGCCGAACTGACCTGGAAGGCCGGCGTCGACGTGCTCTGCTTCGGCGGCACCAAGAACGGCATGGCGGTCGGCGAGGCGG
TGATCTTCTTCGACCGAAAACTCGCGGAGGATTTCGACTATCGCTGCAAGCAGGCGGGCCAGCTCGCCTCGAAGATGCGC
TACCTCTCGGCGCCCTGGGTCGGCATGCTGGAGAACGGGGCGTGGCTCGACAACGCCCGCCACGCCAATGAATGCGCCCG
ACGGCTGGTGCGGGGGATCGCCGACGTGCCGGGCATCTCGCTCGCGGCACCGGTGGAAGCCAACGGCGTCTTCCTGAACC
TGCCCGCGCCGGTCCAAGAAGGGCTGCGCGCCCGCGGCTGGCAGTTCTACGGCTTCATCGGCGGGGCGTCCCGCTTCATG
TTCGCCTGGGATTCAGAGCCGGCGCGGGTCGATGCTCTGGCGCAGGACATCCGTCTCTGCGCCCTGCCCGCGGCGGCGTG
A

Upstream 100 bases:

>100_bases
GCAAAAATCGGCCCTTGGATCGACATGGGTGTCATGAGGCCGGGCGGGTCCCTCACCGCCCGGCCTTCTTTTTGACGCCG
ATAGGAAGCGGGAGCGTGCC

Downstream 100 bases:

>100_bases
TCGCGGCTTCGTTCGCGGCAGGATCAGACGAGATAGGTGATGGTTGCCGCCAGAGCCGTCGCCACGGTGGCGATGGCGAA
ACCCGATGACGAGAGCAGCA

Product: threonine aldolase

Products: NA

Alternate protein names: Low specificity L-TA [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MAEQQFASDNYAGICPEALTAMQAANAGHAPAYGADTWTQAAADGFRRLFETDCEVFFVFNGTAANSLALASLCQSYHSV
ICADSAHIETDECGAPEFFSNGSKLLTAATDDGKLTPEIVRTIAGKRSDIHFPKPRAVTLTQATETGRVYSLDEIAAISA
VCRALGLRLHMDGARFANACASLDASPAELTWKAGVDVLCFGGTKNGMAVGEAVIFFDRKLAEDFDYRCKQAGQLASKMR
YLSAPWVGMLENGAWLDNARHANECARRLVRGIADVPGISLAAPVEANGVFLNLPAPVQEGLRARGWQFYGFIGGASRFM
FAWDSEPARVDALAQDIRLCALPAAA

Sequences:

>Translated_346_residues
MAEQQFASDNYAGICPEALTAMQAANAGHAPAYGADTWTQAAADGFRRLFETDCEVFFVFNGTAANSLALASLCQSYHSV
ICADSAHIETDECGAPEFFSNGSKLLTAATDDGKLTPEIVRTIAGKRSDIHFPKPRAVTLTQATETGRVYSLDEIAAISA
VCRALGLRLHMDGARFANACASLDASPAELTWKAGVDVLCFGGTKNGMAVGEAVIFFDRKLAEDFDYRCKQAGQLASKMR
YLSAPWVGMLENGAWLDNARHANECARRLVRGIADVPGISLAAPVEANGVFLNLPAPVQEGLRARGWQFYGFIGGASRFM
FAWDSEPARVDALAQDIRLCALPAAA
>Mature_345_residues
AEQQFASDNYAGICPEALTAMQAANAGHAPAYGADTWTQAAADGFRRLFETDCEVFFVFNGTAANSLALASLCQSYHSVI
CADSAHIETDECGAPEFFSNGSKLLTAATDDGKLTPEIVRTIAGKRSDIHFPKPRAVTLTQATETGRVYSLDEIAAISAV
CRALGLRLHMDGARFANACASLDASPAELTWKAGVDVLCFGGTKNGMAVGEAVIFFDRKLAEDFDYRCKQAGQLASKMRY
LSAPWVGMLENGAWLDNARHANECARRLVRGIADVPGISLAAPVEANGVFLNLPAPVQEGLRARGWQFYGFIGGASRFMF
AWDSEPARVDALAQDIRLCALPAAA

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. Can also act on L-erythro- phenylserine, L-threo-phenylserine, L-beta-3,4- methylenedioxyphenylserine and L-beta-3,4-dihydroxyphenylserine [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320789, Length=325, Percent_Identity=25.2307692307692, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 36989; Mature: 36858

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEQQFASDNYAGICPEALTAMQAANAGHAPAYGADTWTQAAADGFRRLFETDCEVFFVF
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEE
NGTAANSLALASLCQSYHSVICADSAHIETDECGAPEFFSNGSKLLTAATDDGKLTPEIV
CCCCCHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCHHHCCCCEEEEEECCCCCCCHHHH
RTIAGKRSDIHFPKPRAVTLTQATETGRVYSLDEIAAISAVCRALGLRLHMDGARFANAC
HHHCCCCCCCCCCCCCEEEEEECCCCCCEECHHHHHHHHHHHHHHCCEEEECCHHHHHHH
ASLDASPAELTWKAGVDVLCFGGTKNGMAVGEAVIFFDRKLAEDFDYRCKQAGQLASKMR
HCCCCCCCCEEEECCCEEEEECCCCCCCHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHH
YLSAPWVGMLENGAWLDNARHANECARRLVRGIADVPGISLAAPVEANGVFLNLPAPVQE
HHCCCCHHEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCEEEECCCHHHH
GLRARGWQFYGFIGGASRFMFAWDSEPARVDALAQDIRLCALPAAA
HHHHCCEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AEQQFASDNYAGICPEALTAMQAANAGHAPAYGADTWTQAAADGFRRLFETDCEVFFVF
CCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEE
NGTAANSLALASLCQSYHSVICADSAHIETDECGAPEFFSNGSKLLTAATDDGKLTPEIV
CCCCCHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCHHHCCCCEEEEEECCCCCCCHHHH
RTIAGKRSDIHFPKPRAVTLTQATETGRVYSLDEIAAISAVCRALGLRLHMDGARFANAC
HHHCCCCCCCCCCCCCEEEEEECCCCCCEECHHHHHHHHHHHHHHCCEEEECCHHHHHHH
ASLDASPAELTWKAGVDVLCFGGTKNGMAVGEAVIFFDRKLAEDFDYRCKQAGQLASKMR
HCCCCCCCCEEEECCCEEEEECCCCCCCHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHH
YLSAPWVGMLENGAWLDNARHANECARRLVRGIADVPGISLAAPVEANGVFLNLPAPVQE
HHCCCCHHEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCEEEECCCHHHH
GLRARGWQFYGFIGGASRFMFAWDSEPARVDALAQDIRLCALPAAA
HHHHCCEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9464392 [H]