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The map label for this gene is aatC [H]

Identifier: 218531343

GI number: 218531343

Start: 3595998

End: 3597218

Strand: Reverse

Name: aatC [H]

Synonym: Mchl_3411

Alternate gene names: 218531343

Gene position: 3597218-3595998 (Counterclockwise)

Preceding gene: 218531344

Following gene: 218531342

Centisome position: 62.26

GC content: 67.08

Gene sequence:

>1221_bases
ATGACCGATTTCCACCGCATCAAGCGCCTTCCGCCTTACGTCTTCGAGCAGGTGAACCGGATCAAGGCCGCCGCCCGAGC
CCGCGGCGCCGACATCATCGATCTCGGCATGGGCAATCCCGATCTCGACGCGCCGCGCCACGTCATCGAGAAGCTCGTCG
AGACCGCCGGCAAGCCGCGCACCGACCGCTACTCCGCCTCCAAGGGCATTGCCGGCCTGCGCCGCGCCCAGGCCGGCTAC
TACCAGCGCCGCTTCGGGGTGAGCCTCAACCCGGACACGCAGGTGGTGGCGACGCTCGGCTCGAAGGAGGGCTTCGCAAA
CATGGCCCAGGCGATCACCGCGCCCGGCGACGTGGTGCTGGTGCCGAACCCGAGCTACCCGATCCACGCCTTCGGCTTCC
TGATGGCGGGCGGCGTGATCCGCTCCGTGCCCGCCGAGCCGACCCCGGCGATGTTCCCGGCCCTGGAAAAGGCGGTCGTC
CACTCGATCCCGAAGCCGGTGGCGCTCGTCGTCTGCTACCCCTCGAACCCGACGGCCTACGTCGCGAGCCTCGACTTCTA
CCGGGATCTCGTCGCCTTCGCGAAGAAGCACGAACTGATCCTGCTCTCGGATCTCGCCTATGCCGAGGTCTATTTCGACG
ACAACAACCCGCCGCCCTCCGTGCTGCAGGTGCCGGGCGCGATCGACTGCACCGTGGAATTCACCTCGCTGTCGAAGACC
TTCTCGATGGCGGGCTGGCGCATGGGCTTCGCCGTCGGCAACGAGCGCCTGCTCGCGGCGCTGACGCGGGTGAAGTCCTA
CCTCGATTACGGTGCCTTCACGCCGATCCAGGTTGCAGCCACCGCCGCGCTCAACGGACCGGACGACTGCATCAAGGAGA
TGCGCGCGACCTACAAGAAGCGCCGCGACGCCCTGGTCGAGTCCTTCGGCAAGGCCGGCTGGAAGCTGCCGACGCCCGAA
GCCTCGATGTTCGCCTGGGTGCCGATCCCGGAAAAATTCCGGGACCTCGGCAGCCTGGAATTCTCCAAGCTGCTTCTGGA
AAAGTCGGATGTCGCCGTGGCGCCGGGGATCGGCTTCGGTGAGCACGGGGACGATTACGTCCGCATCGCGCTCGTCGAGA
ATGAGCAGCGCATCCGGCAGGCGGCCCGTAACGTCCGCCGCTTCTTCGACAACGCCGACCGCACGCTCCACAACGTCGTG
CCGTTGCAGAAGGCGGTCTAG

Upstream 100 bases:

>100_bases
AGTCGGCGCGCGAACGCGTCGATGGTAAACAGGCAGGCTCCTCACCGCCGACGCATCCTCGCGGGAGGATCAGTTCCGCG
ACACCGGACAGACCAACGCC

Downstream 100 bases:

>100_bases
CATCCTGTGACGCCGATCCCGACTGATGGCGGGATCGGCGCGGCTGGATGAACCGCGCCGGACGTTGTTGCGGCGGGGCG
ACAGGGCCCGCGCAATCGGC

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MTDFHRIKRLPPYVFEQVNRIKAAARARGADIIDLGMGNPDLDAPRHVIEKLVETAGKPRTDRYSASKGIAGLRRAQAGY
YQRRFGVSLNPDTQVVATLGSKEGFANMAQAITAPGDVVLVPNPSYPIHAFGFLMAGGVIRSVPAEPTPAMFPALEKAVV
HSIPKPVALVVCYPSNPTAYVASLDFYRDLVAFAKKHELILLSDLAYAEVYFDDNNPPPSVLQVPGAIDCTVEFTSLSKT
FSMAGWRMGFAVGNERLLAALTRVKSYLDYGAFTPIQVAATAALNGPDDCIKEMRATYKKRRDALVESFGKAGWKLPTPE
ASMFAWVPIPEKFRDLGSLEFSKLLLEKSDVAVAPGIGFGEHGDDYVRIALVENEQRIRQAARNVRRFFDNADRTLHNVV
PLQKAV

Sequences:

>Translated_406_residues
MTDFHRIKRLPPYVFEQVNRIKAAARARGADIIDLGMGNPDLDAPRHVIEKLVETAGKPRTDRYSASKGIAGLRRAQAGY
YQRRFGVSLNPDTQVVATLGSKEGFANMAQAITAPGDVVLVPNPSYPIHAFGFLMAGGVIRSVPAEPTPAMFPALEKAVV
HSIPKPVALVVCYPSNPTAYVASLDFYRDLVAFAKKHELILLSDLAYAEVYFDDNNPPPSVLQVPGAIDCTVEFTSLSKT
FSMAGWRMGFAVGNERLLAALTRVKSYLDYGAFTPIQVAATAALNGPDDCIKEMRATYKKRRDALVESFGKAGWKLPTPE
ASMFAWVPIPEKFRDLGSLEFSKLLLEKSDVAVAPGIGFGEHGDDYVRIALVENEQRIRQAARNVRRFFDNADRTLHNVV
PLQKAV
>Mature_405_residues
TDFHRIKRLPPYVFEQVNRIKAAARARGADIIDLGMGNPDLDAPRHVIEKLVETAGKPRTDRYSASKGIAGLRRAQAGYY
QRRFGVSLNPDTQVVATLGSKEGFANMAQAITAPGDVVLVPNPSYPIHAFGFLMAGGVIRSVPAEPTPAMFPALEKAVVH
SIPKPVALVVCYPSNPTAYVASLDFYRDLVAFAKKHELILLSDLAYAEVYFDDNNPPPSVLQVPGAIDCTVEFTSLSKTF
SMAGWRMGFAVGNERLLAALTRVKSYLDYGAFTPIQVAATAALNGPDDCIKEMRATYKKRRDALVESFGKAGWKLPTPEA
SMFAWVPIPEKFRDLGSLEFSKLLLEKSDVAVAPGIGFGEHGDDYVRIALVENEQRIRQAARNVRRFFDNADRTLHNVVP
LQKAV

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=395, Percent_Identity=21.5189873417722, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI169881279, Length=395, Percent_Identity=21.5189873417722, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI56713256, Length=342, Percent_Identity=22.8070175438596, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI56713254, Length=342, Percent_Identity=22.8070175438596, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI169881281, Length=243, Percent_Identity=21.3991769547325, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1788722, Length=386, Percent_Identity=50.7772020725389, Blast_Score=415, Evalue=1e-117,
Organism=Escherichia coli, GI1786816, Length=387, Percent_Identity=25.0645994832041, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1788627, Length=386, Percent_Identity=25.3886010362694, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1787710, Length=335, Percent_Identity=24.7761194029851, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17567369, Length=413, Percent_Identity=24.455205811138, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI71994472, Length=389, Percent_Identity=24.9357326478149, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71994476, Length=396, Percent_Identity=24.7474747474747, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6322401, Length=399, Percent_Identity=22.8070175438596, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28573069, Length=390, Percent_Identity=25.1282051282051, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24646114, Length=390, Percent_Identity=25.1282051282051, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI28573067, Length=390, Percent_Identity=25.1282051282051, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI28573065, Length=390, Percent_Identity=25.1282051282051, Blast_Score=112, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 44554; Mature: 44422

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDFHRIKRLPPYVFEQVNRIKAAARARGADIIDLGMGNPDLDAPRHVIEKLVETAGKPR
CCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCC
TDRYSASKGIAGLRRAQAGYYQRRFGVSLNPDTQVVATLGSKEGFANMAQAITAPGDVVL
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCEEE
VPNPSYPIHAFGFLMAGGVIRSVPAEPTPAMFPALEKAVVHSIPKPVALVVCYPSNPTAY
ECCCCCCHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCEE
VASLDFYRDLVAFAKKHELILLSDLAYAEVYFDDNNPPPSVLQVPGAIDCTVEFTSLSKT
EEHHHHHHHHHHHHHCCCEEEEECCEEEEEEECCCCCCCCEEECCCCEEEEEEEHHHHHH
FSMAGWRMGFAVGNERLLAALTRVKSYLDYGAFTPIQVAATAALNGPDDCIKEMRATYKK
HHHCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHH
RRDALVESFGKAGWKLPTPEASMFAWVPIPEKFRDLGSLEFSKLLLEKSDVAVAPGIGFG
HHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHCCCHHHHHHHHHCCCEEEECCCCCC
EHGDDYVRIALVENEQRIRQAARNVRRFFDNADRTLHNVVPLQKAV
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCC
>Mature Secondary Structure 
TDFHRIKRLPPYVFEQVNRIKAAARARGADIIDLGMGNPDLDAPRHVIEKLVETAGKPR
CCHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCC
TDRYSASKGIAGLRRAQAGYYQRRFGVSLNPDTQVVATLGSKEGFANMAQAITAPGDVVL
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCEEE
VPNPSYPIHAFGFLMAGGVIRSVPAEPTPAMFPALEKAVVHSIPKPVALVVCYPSNPTAY
ECCCCCCHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCEE
VASLDFYRDLVAFAKKHELILLSDLAYAEVYFDDNNPPPSVLQVPGAIDCTVEFTSLSKT
EEHHHHHHHHHHHHHCCCEEEEECCEEEEEEECCCCCCCCEEECCCCEEEEEEEHHHHHH
FSMAGWRMGFAVGNERLLAALTRVKSYLDYGAFTPIQVAATAALNGPDDCIKEMRATYKK
HHHCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHH
RRDALVESFGKAGWKLPTPEASMFAWVPIPEKFRDLGSLEFSKLLLEKSDVAVAPGIGFG
HHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHCCCHHHHHHHHHCCCEEEECCCCCC
EHGDDYVRIALVENEQRIRQAARNVRRFFDNADRTLHNVVPLQKAV
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430; 9734305 [H]