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The map label for this gene is atoS [C]

Identifier: 218531302

GI number: 218531302

Start: 3552751

End: 3554493

Strand: Reverse

Name: atoS [C]

Synonym: Mchl_3366

Alternate gene names: 218531302

Gene position: 3554493-3552751 (Counterclockwise)

Preceding gene: 218531306

Following gene: 218531300

Centisome position: 61.52

GC content: 69.59

Gene sequence:

>1743_bases
ATGCTGGTGCGAACGGGTGCCTCCTTCGGCACCCCGCTCCCGCCCCTCGTCGACGAGAGGAGCTACCGGCGGGTGCTCGA
CACGGGCGAGCCCACCATCGGCGACGTCGCGGCCTCGGCCTCCAGCAGCGGTCCGCCGCGGGCTAGCTTCCGCGTGCCCA
TCCGGCGCGACGGCGCGATCCGCTACGTGCTGACGGGTGTCGTCTCCAACGAGCGACTGACCGCGCTCCTCGCGACGACC
GGCCTCGATCCCGCTTGGCGGCCCTACCTCGTCGACGGCTCAAGCCGCATAGCCGCTAGCCTGCGCAGGCCCGATACCGT
GGGTCGGCAGGCGATGGCGCCAACCGTCCGCGCCCGGGAAGGTAGCGCGTCGGGCGTCTACGACGGCATCTCGCCGGAAG
GCGAGCTGCTGGTGACCGCCTTCCGCAAGTCGGATCGGACGGGTTGGTCGGTGCATGTCGCCATTCCGCTCGCCGTCTAC
AACCACCCTATGAACAGGGCTGCCTGGGTGCTGGCCGGCGCCGGGGCCGCTGCGGTCCTGCTAACGGCAGCCTTCATCCT
CTTGCTGCGACGCGAGCTTCGGGTGCAGCGTAGGGAGACGCTCACCCAGGAACGGGCGGTGCGCATGGAAGTGCTCGGGC
GCATGACGGGCGGTGTCGCGCACGACTTCAACAACCTGCTTATGGTCATCCTGGGCAATCTGGAGATGCTCGGGCGGCGC
AACCAGGAGTCGCGCCTGGAGCGCTACGTCACAGCCATCCGCAAGGCGGCCGAGCGCGGCACACACCTCACCCGCGAGTT
GCTCGCCTTCTCGCGCGGCCAGGGCAGCCAGTCCGAGGTGGTGGACCTGAACGAGCGGCTGGTCGGCACGCTCACCATGA
TCTGGCAGTCGGTCAGCGGCCACATCCACGTCGAGACCGACCTCGTCCCCGGCCGGCACGCCGTCAGGCTCGACCCGCTG
CAGTTCGACCTCGCGCTGCTGAACATCGCCGCCAACGCTCGCGACGCCATGCCGGAGGGCGGCAGCCTGCGGATCGCGAC
CCGCCGGGCCCTGCTGCCGGACCGGTCCGGGCGCGAAGGGATCGCGTTGTCCATCAAGGACACGGGCGGCGGCATCCCGC
CGGAAGCCCTGCCGCACGTGTTCGAGCCGTTCTTCACGACCAAGGACGTTGGGAAGGGGACCGGCCTCGGCCTGAGCCAG
GTCTTCGGCTTCGCCAAGCAGTCGGGCGGCGCGGCCGACATCGAGTGCCGGTCAGGACAGGGCACGACCGTCACCCTGCA
CTTGCCGCTGGCGCAGGAAGAGGTACCGGCAGCGAGGATGCTTGCGGACGCAGATGGAGCCTCGCCAAGCTCGACCGCGG
CCCGGGTGGTCCTGATCGATGACAACGACGAGGTGCGCACCGTGACGGCCTCCTTCCTGGAGGATGCTGGCTTCCGGGTC
GAGCAAGCCAACTCTGCGCAGGCCGGGTTGGACCTGCTTGAGCGAAGTGGTGCCGACATCCTGGTGAGCGACTTGGTCAT
GCCCGGCGGCATGGACGGGCTGGCGTTTGCCAACGAGGCGCGCCGGCGCTGGCCGCACCTGCCGGTGATCCTGGTGTCGG
GCTACAGCACCTCCACGGCGCGGGCGACCGAGCTTGGCTACTCGCTCTACATGAAGCCGTTCGACATGGCCGAGCTCGCC
AAGGGCATCCGGGCTCAGCTAGGCCCGAGAGACCGACAGTTGGCGGTGCCGGGACCTAGTTGA

Upstream 100 bases:

>100_bases
AAGGCAGATGTAGCGCGTGCCGTGACCCTGCCATCAAGATCACCAACGTCACCGCCTTCCGCCCTGGCACCGCATCATCC
TCGCCGACACCGAGGGCCAC

Downstream 100 bases:

>100_bases
CCGCTGCGACCGGAGCAAGCTGGGATAGCCTGAACCGAGGCCACACGCTCCTCTCTGCCACTTCAGCCTTGTCCCTCGCC
GTCCTCAGCCGGCCTGCGGC

Product: histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 580; Mature: 580

Protein sequence:

>580_residues
MLVRTGASFGTPLPPLVDERSYRRVLDTGEPTIGDVAASASSSGPPRASFRVPIRRDGAIRYVLTGVVSNERLTALLATT
GLDPAWRPYLVDGSSRIAASLRRPDTVGRQAMAPTVRAREGSASGVYDGISPEGELLVTAFRKSDRTGWSVHVAIPLAVY
NHPMNRAAWVLAGAGAAAVLLTAAFILLLRRELRVQRRETLTQERAVRMEVLGRMTGGVAHDFNNLLMVILGNLEMLGRR
NQESRLERYVTAIRKAAERGTHLTRELLAFSRGQGSQSEVVDLNERLVGTLTMIWQSVSGHIHVETDLVPGRHAVRLDPL
QFDLALLNIAANARDAMPEGGSLRIATRRALLPDRSGREGIALSIKDTGGGIPPEALPHVFEPFFTTKDVGKGTGLGLSQ
VFGFAKQSGGAADIECRSGQGTTVTLHLPLAQEEVPAARMLADADGASPSSTAARVVLIDDNDEVRTVTASFLEDAGFRV
EQANSAQAGLDLLERSGADILVSDLVMPGGMDGLAFANEARRRWPHLPVILVSGYSTSTARATELGYSLYMKPFDMAELA
KGIRAQLGPRDRQLAVPGPS

Sequences:

>Translated_580_residues
MLVRTGASFGTPLPPLVDERSYRRVLDTGEPTIGDVAASASSSGPPRASFRVPIRRDGAIRYVLTGVVSNERLTALLATT
GLDPAWRPYLVDGSSRIAASLRRPDTVGRQAMAPTVRAREGSASGVYDGISPEGELLVTAFRKSDRTGWSVHVAIPLAVY
NHPMNRAAWVLAGAGAAAVLLTAAFILLLRRELRVQRRETLTQERAVRMEVLGRMTGGVAHDFNNLLMVILGNLEMLGRR
NQESRLERYVTAIRKAAERGTHLTRELLAFSRGQGSQSEVVDLNERLVGTLTMIWQSVSGHIHVETDLVPGRHAVRLDPL
QFDLALLNIAANARDAMPEGGSLRIATRRALLPDRSGREGIALSIKDTGGGIPPEALPHVFEPFFTTKDVGKGTGLGLSQ
VFGFAKQSGGAADIECRSGQGTTVTLHLPLAQEEVPAARMLADADGASPSSTAARVVLIDDNDEVRTVTASFLEDAGFRV
EQANSAQAGLDLLERSGADILVSDLVMPGGMDGLAFANEARRRWPHLPVILVSGYSTSTARATELGYSLYMKPFDMAELA
KGIRAQLGPRDRQLAVPGPS
>Mature_580_residues
MLVRTGASFGTPLPPLVDERSYRRVLDTGEPTIGDVAASASSSGPPRASFRVPIRRDGAIRYVLTGVVSNERLTALLATT
GLDPAWRPYLVDGSSRIAASLRRPDTVGRQAMAPTVRAREGSASGVYDGISPEGELLVTAFRKSDRTGWSVHVAIPLAVY
NHPMNRAAWVLAGAGAAAVLLTAAFILLLRRELRVQRRETLTQERAVRMEVLGRMTGGVAHDFNNLLMVILGNLEMLGRR
NQESRLERYVTAIRKAAERGTHLTRELLAFSRGQGSQSEVVDLNERLVGTLTMIWQSVSGHIHVETDLVPGRHAVRLDPL
QFDLALLNIAANARDAMPEGGSLRIATRRALLPDRSGREGIALSIKDTGGGIPPEALPHVFEPFFTTKDVGKGTGLGLSQ
VFGFAKQSGGAADIECRSGQGTTVTLHLPLAQEEVPAARMLADADGASPSSTAARVVLIDDNDEVRTVTASFLEDAGFRV
EQANSAQAGLDLLERSGADILVSDLVMPGGMDGLAFANEARRRWPHLPVILVSGYSTSTARATELGYSLYMKPFDMAELA
KGIRAQLGPRDRQLAVPGPS

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=227, Percent_Identity=31.7180616740088, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1790436, Length=271, Percent_Identity=28.4132841328413, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1788713, Length=280, Percent_Identity=25, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI48994928, Length=226, Percent_Identity=29.646017699115, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790300, Length=251, Percent_Identity=27.4900398406374, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87081816, Length=223, Percent_Identity=27.3542600896861, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI145693157, Length=359, Percent_Identity=22.5626740947075, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 62250; Mature: 62250

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVRTGASFGTPLPPLVDERSYRRVLDTGEPTIGDVAASASSSGPPRASFRVPIRRDGAI
CEEECCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHCCCCCCCCCCEEEEEECCCCCE
RYVLTGVVSNERLTALLATTGLDPAWRPYLVDGSSRIAASLRRPDTVGRQAMAPTVRARE
EEEEEECCCCCCEEEEEEECCCCCCCCCEEECCCHHHHHHHCCCCHHCHHHHCCCCCCCC
GSASGVYDGISPEGELLVTAFRKSDRTGWSVHVAIPLAVYNHPMNRAAWVLAGAGAAAVL
CCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEEEEEEECCCCCCCEEEEEECCCHHHHH
LTAAFILLLRRELRVQRRETLTQERAVRMEVLGRMTGGVAHDFNNLLMVILGNLEMLGRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHCCC
NQESRLERYVTAIRKAAERGTHLTRELLAFSRGQGSQSEVVDLNERLVGTLTMIWQSVSG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
HIHVETDLVPGRHAVRLDPLQFDLALLNIAANARDAMPEGGSLRIATRRALLPDRSGREG
CEEEEEECCCCCCEEEECCHHHHHHHHHHHCCHHHCCCCCCCEEEEEEHHCCCCCCCCCC
IALSIKDTGGGIPPEALPHVFEPFFTTKDVGKGTGLGLSQVFGFAKQSGGAADIECRSGQ
EEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCC
GTTVTLHLPLAQEEVPAARMLADADGASPSSTAARVVLIDDNDEVRTVTASFLEDAGFRV
CCEEEEEECCCHHHCCHHHHHHCCCCCCCCCCCEEEEEECCCCCEEHHHHHHHHHCCCEE
EQANSAQAGLDLLERSGADILVSDLVMPGGMDGLAFANEARRRWPHLPVILVSGYSTSTA
ECCCCHHHHHHHHHHCCCCEEEEHHCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCC
RATELGYSLYMKPFDMAELAKGIRAQLGPRDRQLAVPGPS
HHHHHCCEEEECCCCHHHHHHHHHHHCCCCCCEEECCCCC
>Mature Secondary Structure
MLVRTGASFGTPLPPLVDERSYRRVLDTGEPTIGDVAASASSSGPPRASFRVPIRRDGAI
CEEECCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHCCCCCCCCCCEEEEEECCCCCE
RYVLTGVVSNERLTALLATTGLDPAWRPYLVDGSSRIAASLRRPDTVGRQAMAPTVRARE
EEEEEECCCCCCEEEEEEECCCCCCCCCEEECCCHHHHHHHCCCCHHCHHHHCCCCCCCC
GSASGVYDGISPEGELLVTAFRKSDRTGWSVHVAIPLAVYNHPMNRAAWVLAGAGAAAVL
CCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEEEEEEECCCCCCCEEEEEECCCHHHHH
LTAAFILLLRRELRVQRRETLTQERAVRMEVLGRMTGGVAHDFNNLLMVILGNLEMLGRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHCCC
NQESRLERYVTAIRKAAERGTHLTRELLAFSRGQGSQSEVVDLNERLVGTLTMIWQSVSG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
HIHVETDLVPGRHAVRLDPLQFDLALLNIAANARDAMPEGGSLRIATRRALLPDRSGREG
CEEEEEECCCCCCEEEECCHHHHHHHHHHHCCHHHCCCCCCCEEEEEEHHCCCCCCCCCC
IALSIKDTGGGIPPEALPHVFEPFFTTKDVGKGTGLGLSQVFGFAKQSGGAADIECRSGQ
EEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCC
GTTVTLHLPLAQEEVPAARMLADADGASPSSTAARVVLIDDNDEVRTVTASFLEDAGFRV
CCEEEEEECCCHHHCCHHHHHHCCCCCCCCCCCEEEEEECCCCCEEHHHHHHHHHCCCEE
EQANSAQAGLDLLERSGADILVSDLVMPGGMDGLAFANEARRRWPHLPVILVSGYSTSTA
ECCCCHHHHHHHHHHCCCCEEEEHHCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCC
RATELGYSLYMKPFDMAELAKGIRAQLGPRDRQLAVPGPS
HHHHHCCEEEECCCCHHHHHHHHHHHCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA