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The map label for this gene is cdd [H]

Identifier: 218531143

GI number: 218531143

Start: 3373925

End: 3374338

Strand: Reverse

Name: cdd [H]

Synonym: Mchl_3193

Alternate gene names: 218531143

Gene position: 3374338-3373925 (Counterclockwise)

Preceding gene: 218531145

Following gene: 218531142

Centisome position: 58.4

GC content: 73.19

Gene sequence:

>414_bases
GTGACCGAGCCCGATCTCGATGCCCTGTTCGCGGCGGCCACCGCCGTGCGCGCACGGGCCCATGCGCCCTATTCGGGCTT
CGCCGTCGGCGCCGCCTTGGTGGATGACGCGGGCGGCGTCCATGCCGGCTGCAACGTCGAGAACGCCGCCTACCCCGTCG
GCACCTGCGCCGAGGCCGGCGCCATCGCCGCGATGATCGCGGCCGGCGGACGGCAGATCCGGGCGATCCTCGTTCTCGCC
GATAGTCCCGCCCCGGTGACACCCTGCGGCGCCTGCCGCCAGCGCATCCGGGAATTCGCGGGTCCCGACACGCCGATCGT
CTCGGCCGGTCCCGACGGCGTGCGGGCGCGCTACACGCTGGAGCAATTGCTGCCCGCCTCCTTCGGCCCGGAGCATTTCG
TCCATGGCACCTGA

Upstream 100 bases:

>100_bases
TAGAAGCCGTGCGCGCCTCTGTCGACCGTTGCCCTCTCGACAGGGCCCCTTTCCTCGGGCCAAACCGCAGGATGCACTGC
GAACCGCTCAGGCCTCATCC

Downstream 100 bases:

>100_bases
CGACGCGGCCATCGCCCCTCTGCGCGCGGCAGGCTTTTCCGGGCCCTATGCCCTGGCGATCGTCACGGGGACTGGGCTCG
GCGCCCTGGTCGAGGCGGTC

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 137; Mature: 136

Protein sequence:

>137_residues
MTEPDLDALFAAATAVRARAHAPYSGFAVGAALVDDAGGVHAGCNVENAAYPVGTCAEAGAIAAMIAAGGRQIRAILVLA
DSPAPVTPCGACRQRIREFAGPDTPIVSAGPDGVRARYTLEQLLPASFGPEHFVHGT

Sequences:

>Translated_137_residues
MTEPDLDALFAAATAVRARAHAPYSGFAVGAALVDDAGGVHAGCNVENAAYPVGTCAEAGAIAAMIAAGGRQIRAILVLA
DSPAPVTPCGACRQRIREFAGPDTPIVSAGPDGVRARYTLEQLLPASFGPEHFVHGT
>Mature_136_residues
TEPDLDALFAAATAVRARAHAPYSGFAVGAALVDDAGGVHAGCNVENAAYPVGTCAEAGAIAAMIAAGGRQIRAILVLAD
SPAPVTPCGACRQRIREFAGPDTPIVSAGPDGVRARYTLEQLLPASFGPEHFVHGT

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=129, Percent_Identity=42.6356589147287, Blast_Score=114, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17540514, Length=125, Percent_Identity=40.8, Blast_Score=92, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17551074, Length=123, Percent_Identity=39.0243902439024, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323274, Length=136, Percent_Identity=37.5, Blast_Score=94, Evalue=1e-20,
Organism=Drosophila melanogaster, GI19920920, Length=132, Percent_Identity=47.7272727272727, Blast_Score=99, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24582741, Length=132, Percent_Identity=40.9090909090909, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24582744, Length=106, Percent_Identity=46.2264150943396, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 13853; Mature: 13722

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPDLDALFAAATAVRARAHAPYSGFAVGAALVDDAGGVHAGCNVENAAYPVGTCAEAG
CCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHH
AIAAMIAAGGRQIRAILVLADSPAPVTPCGACRQRIREFAGPDTPIVSAGPDGVRARYTL
HHHHHHHCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
EQLLPASFGPEHFVHGT
HHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TEPDLDALFAAATAVRARAHAPYSGFAVGAALVDDAGGVHAGCNVENAAYPVGTCAEAG
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHH
AIAAMIAAGGRQIRAILVLADSPAPVTPCGACRQRIREFAGPDTPIVSAGPDGVRARYTL
HHHHHHHCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
EQLLPASFGPEHFVHGT
HHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8349569 [H]