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The map label for this gene is rsbP [H]

Identifier: 218236127

GI number: 218236127

Start: 1011993

End: 1013135

Strand: Direct

Name: rsbP [H]

Synonym: BCB4264_A1035

Alternate gene names: 218236127

Gene position: 1011993-1013135 (Clockwise)

Preceding gene: 218233427

Following gene: 218232730

Centisome position: 18.67

GC content: 32.11

Gene sequence:

>1143_bases
GTGTCCATTTTAATTGTCGATGATAATCCGGTTAACATCTTTGTAATTGAAAAAATTTTAAAACAAGCCGGATATCAGGA
TCTTGTATCGCTGAATTCTGCACAAGAGCTTTTCGAATACATTCAATTTGGAGAAGATTCTTCCAGGTATAATGAAATTG
ATTTAATCTTATTAGATATTATGATGCCTGAAATTGATGGACTTGAAGTTTGTAGGCGATTACAAAAAGAGGAGAAGTTT
AAAGATATTCCTATTATTTTTGTTACAGCTTTAGAGGATGCCAATAAATTGGCCGAAGCTCTTGATATGGGGGCAATGGA
TTATATTACGAAACCTATAAATAAAGTTGAACTATTAGCACGTATGCGTGTAGCGTTACGCTTGAAATCGGAATTAAATT
GGCATAAAGAACAAGAAGAAAATCTTCGGAATGAATTAGATTTAGCTACGCAAGTACAAAGAAACTTATTAAGTAGCCCA
TTAAGAGAAGATTATATAAAAATTGAAGCAAGTTACTTACCTTCATTTAAATTAGCTGGAGATATGTATTATTGGTATAA
AATCGATGAAAATCGCTACGGTATTATATTATTAGACGTGATGGGACATGGTATATCTGCTTCATTAGTTTGTATGTTTA
TTTCGTCTGTATTACGTGAAACGATTAAATCTTTAATCGATCCAGAACTTGTCATTAAAGACTTAAATAAATATATGACT
CTTTTACATAATGAGAATGACGATATTCCATATTATTTTACAGCGATATATTTAGTAGTAGATACAGAAAAGAGAACGAT
TGAATATGTAAATGCAGGGCATCCTTCTGGATACGTTTTAGTTGATGAAACAAATATGGTTGAACTAAATCGCGGGAGTT
GTGCGGTAGGATTTTTTGATGAAATAAAAGTTAAAAAGACAGTTATACCTTTTGAGAAGAACGCTCAAATCGTATTGTTT
ACAGATGGTGTTCTTGAAGCAATTGCAAATGATGAATTTGAGGCTGAAGAGAAATTACGTACTTTTACAGAAAGAAAATG
GGGAGATTTAGAAGGCGAGATAGAAGGGTTTTACAAGGAAGAACAAAAGAAAGCGCAATCAGATGATATGTGTCTAATTA
TGATACAAACGAATGCGAAATAA

Upstream 100 bases:

>100_bases
TAGAGTAGGAAATTTTCATTTTGTAACTGAGTATGCAATACTAGAAAAATAGAAAATGATAATAGATTTACATTTTAAAT
AAGAAAAGGGGAAATAACTT

Downstream 100 bases:

>100_bases
AAAGCGTATGAAATCCAAACAGAGGATTTCATACGCTTTTTATTGTATTTTTTGATAAATTTGTTCGCTAGGATTAAATT
GGGTATAATGCGGCATTATA

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MSILIVDDNPVNIFVIEKILKQAGYQDLVSLNSAQELFEYIQFGEDSSRYNEIDLILLDIMMPEIDGLEVCRRLQKEEKF
KDIPIIFVTALEDANKLAEALDMGAMDYITKPINKVELLARMRVALRLKSELNWHKEQEENLRNELDLATQVQRNLLSSP
LREDYIKIEASYLPSFKLAGDMYYWYKIDENRYGIILLDVMGHGISASLVCMFISSVLRETIKSLIDPELVIKDLNKYMT
LLHNENDDIPYYFTAIYLVVDTEKRTIEYVNAGHPSGYVLVDETNMVELNRGSCAVGFFDEIKVKKTVIPFEKNAQIVLF
TDGVLEAIANDEFEAEEKLRTFTERKWGDLEGEIEGFYKEEQKKAQSDDMCLIMIQTNAK

Sequences:

>Translated_380_residues
MSILIVDDNPVNIFVIEKILKQAGYQDLVSLNSAQELFEYIQFGEDSSRYNEIDLILLDIMMPEIDGLEVCRRLQKEEKF
KDIPIIFVTALEDANKLAEALDMGAMDYITKPINKVELLARMRVALRLKSELNWHKEQEENLRNELDLATQVQRNLLSSP
LREDYIKIEASYLPSFKLAGDMYYWYKIDENRYGIILLDVMGHGISASLVCMFISSVLRETIKSLIDPELVIKDLNKYMT
LLHNENDDIPYYFTAIYLVVDTEKRTIEYVNAGHPSGYVLVDETNMVELNRGSCAVGFFDEIKVKKTVIPFEKNAQIVLF
TDGVLEAIANDEFEAEEKLRTFTERKWGDLEGEIEGFYKEEQKKAQSDDMCLIMIQTNAK
>Mature_379_residues
SILIVDDNPVNIFVIEKILKQAGYQDLVSLNSAQELFEYIQFGEDSSRYNEIDLILLDIMMPEIDGLEVCRRLQKEEKFK
DIPIIFVTALEDANKLAEALDMGAMDYITKPINKVELLARMRVALRLKSELNWHKEQEENLRNELDLATQVQRNLLSSPL
REDYIKIEASYLPSFKLAGDMYYWYKIDENRYGIILLDVMGHGISASLVCMFISSVLRETIKSLIDPELVIKDLNKYMTL
LHNENDDIPYYFTAIYLVVDTEKRTIEYVNAGHPSGYVLVDETNMVELNRGSCAVGFFDEIKVKKTVIPFEKNAQIVLFT
DGVLEAIANDEFEAEEKLRTFTERKWGDLEGEIEGFYKEEQKKAQSDDMCLIMIQTNAK

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to energy stress [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=139, Percent_Identity=36.6906474820144, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788394, Length=126, Percent_Identity=37.3015873015873, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87082012, Length=136, Percent_Identity=33.0882352941176, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1786599, Length=126, Percent_Identity=31.7460317460317, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786784, Length=127, Percent_Identity=33.8582677165354, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1786911, Length=130, Percent_Identity=36.9230769230769, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789149, Length=113, Percent_Identity=32.7433628318584, Blast_Score=63, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=116, Percent_Identity=30.1724137931034, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR001932
- InterPro:   IPR010822 [H]

Pfam domain/function: PF00989 PAS; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 43872; Mature: 43741

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILIVDDNPVNIFVIEKILKQAGYQDLVSLNSAQELFEYIQFGEDSSRYNEIDLILLDI
CEEEEECCCCCEEHHHHHHHHHCCHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHEEEEEH
MMPEIDGLEVCRRLQKEEKFKDIPIIFVTALEDANKLAEALDMGAMDYITKPINKVELLA
HCCCCCHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHCCCHHHHHHCCHHHHHHHH
RMRVALRLKSELNWHKEQEENLRNELDLATQVQRNLLSSPLREDYIKIEASYLPSFKLAG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEEEHHHCCCEEEEC
DMYYWYKIDENRYGIILLDVMGHGISASLVCMFISSVLRETIKSLIDPELVIKDLNKYMT
CEEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
LLHNENDDIPYYFTAIYLVVDTEKRTIEYVNAGHPSGYVLVDETNMVELNRGSCAVGFFD
HHCCCCCCCCEEEEEEEEEEECCCCEEEEEECCCCCCEEEEECCCEEEECCCCEEEECHH
EIKVKKTVIPFEKNAQIVLFTDGVLEAIANDEFEAEEKLRTFTERKWGDLEGEIEGFYKE
HHEEEEEECCCCCCCEEEEEECHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHH
EQKKAQSDDMCLIMIQTNAK
HHHHCCCCCEEEEEEECCCC
>Mature Secondary Structure 
SILIVDDNPVNIFVIEKILKQAGYQDLVSLNSAQELFEYIQFGEDSSRYNEIDLILLDI
EEEEECCCCCEEHHHHHHHHHCCHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHEEEEEH
MMPEIDGLEVCRRLQKEEKFKDIPIIFVTALEDANKLAEALDMGAMDYITKPINKVELLA
HCCCCCHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHCCCHHHHHHCCHHHHHHHH
RMRVALRLKSELNWHKEQEENLRNELDLATQVQRNLLSSPLREDYIKIEASYLPSFKLAG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEEEHHHCCCEEEEC
DMYYWYKIDENRYGIILLDVMGHGISASLVCMFISSVLRETIKSLIDPELVIKDLNKYMT
CEEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
LLHNENDDIPYYFTAIYLVVDTEKRTIEYVNAGHPSGYVLVDETNMVELNRGSCAVGFFD
HHCCCCCCCCEEEEEEEEEEECCCCEEEEEECCCCCCEEEEECCCEEEECCCCEEEECHH
EIKVKKTVIPFEKNAQIVLFTDGVLEAIANDEFEAEEKLRTFTERKWGDLEGEIEGFYKE
HHEEEEEECCCCCCCEEEEEECHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHH
EQKKAQSDDMCLIMIQTNAK
HHHHCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 10632888 [H]