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The map label for this gene is panC [H]

Identifier: 218236105

GI number: 218236105

Start: 1521589

End: 1522437

Strand: Direct

Name: panC [H]

Synonym: BCB4264_A1596

Alternate gene names: 218236105

Gene position: 1521589-1522437 (Clockwise)

Preceding gene: 218233138

Following gene: 218234024

Centisome position: 28.08

GC content: 36.16

Gene sequence:

>849_bases
ATGAAAATCGTAACTACAGTGCAAGAGATGCAGCAAATTACTAGCGAACTTCGTGCAAGTGGAAAGAGTATTGGTTTTGT
TCCAACAATGGGTTATTTACATGAAGGCCATGCTACTTTATTACGTAAGGCAAGAGAAGAAAATGAAATTGTAGTTTTAA
GTGTATTTGTAAACCCACTACAATTCGGCCCAAATGAAGATTTAGATCGATATCCTCGTGATATTGATAGAGATGAAAAT
GTAGCAAAAGAAAACGGTGTAGATTATTTATTTTATCCGAGTGTAGAAGAAATGTATCCAGCAGAACAAACAACAACAGT
AGAAGTTGTGAAGCGCACGGACGTATTATGCGGTCAACAAAGACCTGGTCATTTCGCTGGTGTTGCAACTGTACTGATGA
AACTATTTAATATTACGGTGCCAACGCGTGCTTATTTCGGTATGAAAGATGCTCAACAAGTTGCAGTAATTGAAGGATTT
GTAACTGATTTCAATATTCCAGTTACAATCGTACCAGTTGATATTGTAAGGGAAGAAGATGGTTTAGCGAAAAGTTCTCG
TAACGTGTACCTATCACAAGATGAACGTGAAGAAGCTCTTCATTTATACCGCAGCCTATGTATAGCGAAAGAAAGAATTG
AGGCAGGTGAACGTAATCCGGAAATCATTACAAATCTTGTGAAAGATTATATTGAGACGCATACGAAAGGCACTGTAGAT
TATGCGGATTTATATGCATATCCGTCATTAACAATGGTAGAGAAAGTCGAAGGAAGAATCATTTTAGCTATTGCAGTTAA
GTTTGAAAATGTAAGATTAATTGACAATATAACATTAACGGTTAAATAA

Upstream 100 bases:

>100_bases
AATATGTTACTGAAGTAAAGACAAGGCAATTTCCTGAAGAAAAACATTCGTTCACAATGAAAGAGGAAGAATGCTTAGTG
TTATATGGAGGAAAACAATA

Downstream 100 bases:

>100_bases
GGGGGAGCATCTATGTTTCGCACAATGATGAGAGCAAAGTTACATCGTGCAACTGTAACGGAGGCAAATTTAAATTATGT
AGGTAGTATTACAATTGATG

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MKIVTTVQEMQQITSELRASGKSIGFVPTMGYLHEGHATLLRKAREENEIVVLSVFVNPLQFGPNEDLDRYPRDIDRDEN
VAKENGVDYLFYPSVEEMYPAEQTTTVEVVKRTDVLCGQQRPGHFAGVATVLMKLFNITVPTRAYFGMKDAQQVAVIEGF
VTDFNIPVTIVPVDIVREEDGLAKSSRNVYLSQDEREEALHLYRSLCIAKERIEAGERNPEIITNLVKDYIETHTKGTVD
YADLYAYPSLTMVEKVEGRIILAIAVKFENVRLIDNITLTVK

Sequences:

>Translated_282_residues
MKIVTTVQEMQQITSELRASGKSIGFVPTMGYLHEGHATLLRKAREENEIVVLSVFVNPLQFGPNEDLDRYPRDIDRDEN
VAKENGVDYLFYPSVEEMYPAEQTTTVEVVKRTDVLCGQQRPGHFAGVATVLMKLFNITVPTRAYFGMKDAQQVAVIEGF
VTDFNIPVTIVPVDIVREEDGLAKSSRNVYLSQDEREEALHLYRSLCIAKERIEAGERNPEIITNLVKDYIETHTKGTVD
YADLYAYPSLTMVEKVEGRIILAIAVKFENVRLIDNITLTVK
>Mature_282_residues
MKIVTTVQEMQQITSELRASGKSIGFVPTMGYLHEGHATLLRKAREENEIVVLSVFVNPLQFGPNEDLDRYPRDIDRDEN
VAKENGVDYLFYPSVEEMYPAEQTTTVEVVKRTDVLCGQQRPGHFAGVATVLMKLFNITVPTRAYFGMKDAQQVAVIEGF
VTDFNIPVTIVPVDIVREEDGLAKSSRNVYLSQDEREEALHLYRSLCIAKERIEAGERNPEIITNLVKDYIETHTKGTVD
YADLYAYPSLTMVEKVEGRIILAIAVKFENVRLIDNITLTVK

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=279, Percent_Identity=40.5017921146953, Blast_Score=197, Evalue=5e-52,
Organism=Saccharomyces cerevisiae, GI6322046, Length=310, Percent_Identity=39.0322580645161, Blast_Score=178, Evalue=8e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 31906; Mature: 31906

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVTTVQEMQQITSELRASGKSIGFVPTMGYLHEGHATLLRKAREENEIVVLSVFVNPL
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHCCCCCEEEEEEEECHH
QFGPNEDLDRYPRDIDRDENVAKENGVDYLFYPSVEEMYPAEQTTTVEVVKRTDVLCGQQ
CCCCCCCHHHCCCCCCCCCCHHHHCCCCEEECCCHHHHCCCCCCHHHHHHHHHHHHCCCC
RPGHFAGVATVLMKLFNITVPTRAYFGMKDAQQVAVIEGFVTDFNIPVTIVPVDIVREED
CCCHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEEECCC
GLAKSSRNVYLSQDEREEALHLYRSLCIAKERIEAGERNPEIITNLVKDYIETHTKGTVD
CCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCC
YADLYAYPSLTMVEKVEGRIILAIAVKFENVRLIDNITLTVK
HHHHHHCCCHHHHHHHCCCEEEEEEEEECCEEEEEEEEEEEC
>Mature Secondary Structure
MKIVTTVQEMQQITSELRASGKSIGFVPTMGYLHEGHATLLRKAREENEIVVLSVFVNPL
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHCCCCCEEEEEEEECHH
QFGPNEDLDRYPRDIDRDENVAKENGVDYLFYPSVEEMYPAEQTTTVEVVKRTDVLCGQQ
CCCCCCCHHHCCCCCCCCCCHHHHCCCCEEECCCHHHHCCCCCCHHHHHHHHHHHHCCCC
RPGHFAGVATVLMKLFNITVPTRAYFGMKDAQQVAVIEGFVTDFNIPVTIVPVDIVREED
CCCHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEEECCC
GLAKSSRNVYLSQDEREEALHLYRSLCIAKERIEAGERNPEIITNLVKDYIETHTKGTVD
CCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCC
YADLYAYPSLTMVEKVEGRIILAIAVKFENVRLIDNITLTVK
HHHHHHCCCHHHHHHHCCCEEEEEEEEECCEEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA