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The map label for this gene is pyc [H]

Identifier: 218236059

GI number: 218236059

Start: 3968900

End: 3972346

Strand: Reverse

Name: pyc [H]

Synonym: BCB4264_A4050

Alternate gene names: 218236059

Gene position: 3972346-3968900 (Counterclockwise)

Preceding gene: 218235251

Following gene: 218231430

Centisome position: 73.3

GC content: 38.12

Gene sequence:

>3447_bases
ATGACAAAGCTGCAACGTATTCAAAAAGTATTGGTAGCTAACCGTGGAGAGATTGCAATTCGTGTGTTTCGAGCTTGTTC
GGAACTTGGATTAAAAACAGTTGCAATCTATTCTAAAGAGGATAGTGGTTCTTATCATCGCTATAAAGCCGATGAGTCCT
ATTTAGTTGGGGAAGGAAAAAAACCAATTGATGCTTATCTAGATATTGAAGGCATTATTGAGATTGCAAAAAGTAATCAT
GTAGATGCAATCCACCCTGGATATGGTTTCTTGTCAGAAAATATTCAATTCGCTAAACGTTGTGAAGAAGAAGGAATTAT
CTTTATCGGTCCGAAAAGTAAGCATTTAGATATGTTTGGAGATAAAGTGAAAGCAAGAACACAAGCGCAGCTAGCACAAA
TTCCAGTTATACCTGGTAGTGATGGTCCAGTAAATTCATTAGAAGAAGTCGAAAAATTTGCTGAAAAGTATGATTACCCG
ATTATTATTAAAGCATCCCTTGGGGGTGGCGGTCGTGGTATGCGTATTGTGCGTACTAGTGAGGAATTAGGAGAATCATA
TAATCGAGCGAAATCAGAAGCGAAAGCAGCCTTTGGTAATGATGAAGTTTACGTCGAAAAATTCGTTGAAAAACCTAAAC
ATATAGAAGTACAAATTTTAGCAGATGAAGAAGGCAATGTTGTTCATTTATACGAGCGTGACTGTTCTGTACAACGTCGT
CATCAAAAAGTTGTAGAAATTGCACCGAGTGTATCACTTTCAGATGATCTGCGTCAGCGTATTTGTGATGCTGCTGTGAA
GTTAACGAAAAATGTAAATTATTTAAATGCAGGAACAGTAGAATTCCTTGTAAAAGATGATGAGTTTTACTTTATTGAAG
TAAATCCACGTGTTCAAGTAGAACATACGATTACAGAAATGATTACGGGAGTAGATATTGTTCAATCACAAATTTTAATA
GCTGATGGACATGCATTACATAGCAAAATGGTAGGTGTTCCGAAGCAAGAGGAAGTAGTTGTACATGGATTTGCAATTCA
ATCTCGTGTAACAACTGAAGATCCGCTAAATAATTTTATGCCGGATACAGGAAAAATTATGGCGTATCGATCAGGCGGTG
GTTTTGGTGTACGTCTTGATACAGGAAATAGCTTCCAAGGTGCAGTTATTACACCGTACTACGATTCTTTACTTGTAAAG
GTTACAACTTGGGCACTTACTTTTGAGCAAGCTGCTGCAAAAATGGAACGTAACTTAAAAGAATTCCGTATTCGTGGTAT
TAAAACAAATATTCCATTCCTAGAGAATGTAGTAAAACATAAAAACTTCTTATCAGGAGAATATGATACTTCATTTATCG
ATGCGTCACCTGAATTGTTCTTGTTCCCGAAACGTAAAGACCGTGGAACGAAAATGTTAAATTACATTGGTACAGTAACA
GTAAATGGTTTCCCAGGGGTAGGTAAAAAAGAAAAACCAATATTCCCAGATGCTCGTATTCCATGTTTAAAACATTCAGA
GCCAATCCAAAATGGAACGAAACAAATTTTGGACGAGCGTGGAGCGGACGGATTAGTAAAATGGGTACAGGATCAAAAGC
GTGTACTTTTAACGGATACAACATTCCGTGATGCACACCAGTCATTACTTGCAACTCGTATTCGTACAAAAGATTTACAT
CAAATTGCGGAGCCAACAGCGAGAATGTTACCGAACCTATTCTCAGCGGAAATGTGGGGCGGTGCAACATTTGACGTTGC
GTATCGTTTCTTAAAAGAAGATCCATGGGAACGATTACTAGATCTTCGTGAAAAAATGCCGAACGTGTTATTCCAAATGT
TACTTCGTTCTTCAAACGCAGTTGGATACAAAAACTATCCAGATAATTTAATTCAAAAATTTGTGGAATGTTCTGCTCAA
GCAGGCATTGATGTATTCCGTATTTTTGATAGCTTAAACTGGGTGGAAGGCATGAGAGTTGCAATTGACGCTGTACGAGA
CACTGGTAAAATTGCAGAAGCAACAATGTGCTACACAGGGGATATTCATGATCCACTGCGTAGTAAATATGATTTAAATT
ACTATAAAAATTTAGCAAAAGAGTTAGAAGCATCAGGAGCTCACATTTTAGGTATTAAAGATATGGCGGGCTTACTAAAA
CCAAATGCAGCATATGATTTAGTTTCTGCATTAAAAGAGACAGTGTCGATTCCAATTCATCTGCACACGCACGATACGAG
TGGAAATGGTATATTAACGTATACGAAGGCAATTGAAGCGGGTGTTGATATCGTCGATGTAGCAGTGAGTTCTATGGCTG
GTCAAACGTCACAACCAAGTGCGAACACGCTATACTATGCATTAGGTGGAAACGAAAGACAACCAGATGTTAATATAGAT
TCTTTAGAAAAACTATCTCATTATTGGGAAGATGTACGCAAATACTATGCACCGTTTGAAAGTGGTATGAATGCGCCGCA
TACAGAGGTATATATGCATGAAATGCCGGGTGGGCAGTATAGTAATCTTCAGCAACAAGCGAAGGCGGTTGGTTTAGGAG
ATCGCTTCGATGAAGTGAAAGTAATGTACCGCCGTGTGAATGACATGTTTGGAGATATTGTAAAAGTAACGCCATCATCA
AAAGTTGTTGGTGATATGGCATTATTTATGGTTCAGAACCATCTGACAGAACAAGATGTTTTAGAGCGTGGACATGCGAT
GGACTTCCCAGGGTCTGTTGTTGAAATGTTCTCTGGTGATTTAGGTCAACCGTACGGTGGTTTCCCGAAAGAATTACAAA
AGATTATTTTAAAAGGGAAAGAGCCATTAACAGTAAGACCAGGTGAATTACTAGAGCCAGTAGATTTCGAAGCGTTAAAA
GAAGAATTATTCCATAAACTTGGACGCGAAGTAACGATTTTTGATGTAGTGGCATATGCTTTATATCCAAAAGTATTTAT
GGATTATGAAAAAGTTGCTGAGCTTTATGGAAATGTATCTGTACTTGATACACCGACGTTCTTCTATGGTATGAGACTAG
GTGAAGAAATTGATGTAGAAATTGAACAGGGTAAAACATTGATGGTTAAACTAGTATCAATTGGAGAACCTCAGCCGGAT
GGAAACCGTGTTCTTTACTTGGAATTCAACGGTCAACCACGTGAAATTATCGTGAAAGATGAGAGTGTAAAAGCAACAGT
TGCACAACGTGTGAAAGGAAACCGTGAGAATCCAAATCATATTAGTGCAACGATGCCAGGAACGGTAATTAAAGTAGTTG
TAAAAGAAGGCGACGAAGTGAAAAAAGGCGATTCTATGGCAATTACAGAAGCGATGAAAATGGAAACGACAGTTCAAGCG
CCGTTCAATGGTAAAGTGAAGAAAGTATATGTTAACGATGGTGATGCAATTCAAACGGGTGATCTACTTATTGAATTAGA
TCACTAA

Upstream 100 bases:

>100_bases
TTCTAAGTATAATATAATGTGGAAAGTGAAGAACTTCACGCTTTTTAAGGTGTGTATATATTTTATCTCTAGAGTGGTAG
GAAAGTAGAGGGGGAAAATC

Downstream 100 bases:

>100_bases
AATAAAAAAAGGGCTGTGTAAATACAGCTCTTTTTTTATTGCAAAAAAATCCCTTGCCAATTCGGCAAGGAATTTTAGTT
TTATATTATTTTGTTTGTTT

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1148; Mature: 1147

Protein sequence:

>1148_residues
MTKLQRIQKVLVANRGEIAIRVFRACSELGLKTVAIYSKEDSGSYHRYKADESYLVGEGKKPIDAYLDIEGIIEIAKSNH
VDAIHPGYGFLSENIQFAKRCEEEGIIFIGPKSKHLDMFGDKVKARTQAQLAQIPVIPGSDGPVNSLEEVEKFAEKYDYP
IIIKASLGGGGRGMRIVRTSEELGESYNRAKSEAKAAFGNDEVYVEKFVEKPKHIEVQILADEEGNVVHLYERDCSVQRR
HQKVVEIAPSVSLSDDLRQRICDAAVKLTKNVNYLNAGTVEFLVKDDEFYFIEVNPRVQVEHTITEMITGVDIVQSQILI
ADGHALHSKMVGVPKQEEVVVHGFAIQSRVTTEDPLNNFMPDTGKIMAYRSGGGFGVRLDTGNSFQGAVITPYYDSLLVK
VTTWALTFEQAAAKMERNLKEFRIRGIKTNIPFLENVVKHKNFLSGEYDTSFIDASPELFLFPKRKDRGTKMLNYIGTVT
VNGFPGVGKKEKPIFPDARIPCLKHSEPIQNGTKQILDERGADGLVKWVQDQKRVLLTDTTFRDAHQSLLATRIRTKDLH
QIAEPTARMLPNLFSAEMWGGATFDVAYRFLKEDPWERLLDLREKMPNVLFQMLLRSSNAVGYKNYPDNLIQKFVECSAQ
AGIDVFRIFDSLNWVEGMRVAIDAVRDTGKIAEATMCYTGDIHDPLRSKYDLNYYKNLAKELEASGAHILGIKDMAGLLK
PNAAYDLVSALKETVSIPIHLHTHDTSGNGILTYTKAIEAGVDIVDVAVSSMAGQTSQPSANTLYYALGGNERQPDVNID
SLEKLSHYWEDVRKYYAPFESGMNAPHTEVYMHEMPGGQYSNLQQQAKAVGLGDRFDEVKVMYRRVNDMFGDIVKVTPSS
KVVGDMALFMVQNHLTEQDVLERGHAMDFPGSVVEMFSGDLGQPYGGFPKELQKIILKGKEPLTVRPGELLEPVDFEALK
EELFHKLGREVTIFDVVAYALYPKVFMDYEKVAELYGNVSVLDTPTFFYGMRLGEEIDVEIEQGKTLMVKLVSIGEPQPD
GNRVLYLEFNGQPREIIVKDESVKATVAQRVKGNRENPNHISATMPGTVIKVVVKEGDEVKKGDSMAITEAMKMETTVQA
PFNGKVKKVYVNDGDAIQTGDLLIELDH

Sequences:

>Translated_1148_residues
MTKLQRIQKVLVANRGEIAIRVFRACSELGLKTVAIYSKEDSGSYHRYKADESYLVGEGKKPIDAYLDIEGIIEIAKSNH
VDAIHPGYGFLSENIQFAKRCEEEGIIFIGPKSKHLDMFGDKVKARTQAQLAQIPVIPGSDGPVNSLEEVEKFAEKYDYP
IIIKASLGGGGRGMRIVRTSEELGESYNRAKSEAKAAFGNDEVYVEKFVEKPKHIEVQILADEEGNVVHLYERDCSVQRR
HQKVVEIAPSVSLSDDLRQRICDAAVKLTKNVNYLNAGTVEFLVKDDEFYFIEVNPRVQVEHTITEMITGVDIVQSQILI
ADGHALHSKMVGVPKQEEVVVHGFAIQSRVTTEDPLNNFMPDTGKIMAYRSGGGFGVRLDTGNSFQGAVITPYYDSLLVK
VTTWALTFEQAAAKMERNLKEFRIRGIKTNIPFLENVVKHKNFLSGEYDTSFIDASPELFLFPKRKDRGTKMLNYIGTVT
VNGFPGVGKKEKPIFPDARIPCLKHSEPIQNGTKQILDERGADGLVKWVQDQKRVLLTDTTFRDAHQSLLATRIRTKDLH
QIAEPTARMLPNLFSAEMWGGATFDVAYRFLKEDPWERLLDLREKMPNVLFQMLLRSSNAVGYKNYPDNLIQKFVECSAQ
AGIDVFRIFDSLNWVEGMRVAIDAVRDTGKIAEATMCYTGDIHDPLRSKYDLNYYKNLAKELEASGAHILGIKDMAGLLK
PNAAYDLVSALKETVSIPIHLHTHDTSGNGILTYTKAIEAGVDIVDVAVSSMAGQTSQPSANTLYYALGGNERQPDVNID
SLEKLSHYWEDVRKYYAPFESGMNAPHTEVYMHEMPGGQYSNLQQQAKAVGLGDRFDEVKVMYRRVNDMFGDIVKVTPSS
KVVGDMALFMVQNHLTEQDVLERGHAMDFPGSVVEMFSGDLGQPYGGFPKELQKIILKGKEPLTVRPGELLEPVDFEALK
EELFHKLGREVTIFDVVAYALYPKVFMDYEKVAELYGNVSVLDTPTFFYGMRLGEEIDVEIEQGKTLMVKLVSIGEPQPD
GNRVLYLEFNGQPREIIVKDESVKATVAQRVKGNRENPNHISATMPGTVIKVVVKEGDEVKKGDSMAITEAMKMETTVQA
PFNGKVKKVYVNDGDAIQTGDLLIELDH
>Mature_1147_residues
TKLQRIQKVLVANRGEIAIRVFRACSELGLKTVAIYSKEDSGSYHRYKADESYLVGEGKKPIDAYLDIEGIIEIAKSNHV
DAIHPGYGFLSENIQFAKRCEEEGIIFIGPKSKHLDMFGDKVKARTQAQLAQIPVIPGSDGPVNSLEEVEKFAEKYDYPI
IIKASLGGGGRGMRIVRTSEELGESYNRAKSEAKAAFGNDEVYVEKFVEKPKHIEVQILADEEGNVVHLYERDCSVQRRH
QKVVEIAPSVSLSDDLRQRICDAAVKLTKNVNYLNAGTVEFLVKDDEFYFIEVNPRVQVEHTITEMITGVDIVQSQILIA
DGHALHSKMVGVPKQEEVVVHGFAIQSRVTTEDPLNNFMPDTGKIMAYRSGGGFGVRLDTGNSFQGAVITPYYDSLLVKV
TTWALTFEQAAAKMERNLKEFRIRGIKTNIPFLENVVKHKNFLSGEYDTSFIDASPELFLFPKRKDRGTKMLNYIGTVTV
NGFPGVGKKEKPIFPDARIPCLKHSEPIQNGTKQILDERGADGLVKWVQDQKRVLLTDTTFRDAHQSLLATRIRTKDLHQ
IAEPTARMLPNLFSAEMWGGATFDVAYRFLKEDPWERLLDLREKMPNVLFQMLLRSSNAVGYKNYPDNLIQKFVECSAQA
GIDVFRIFDSLNWVEGMRVAIDAVRDTGKIAEATMCYTGDIHDPLRSKYDLNYYKNLAKELEASGAHILGIKDMAGLLKP
NAAYDLVSALKETVSIPIHLHTHDTSGNGILTYTKAIEAGVDIVDVAVSSMAGQTSQPSANTLYYALGGNERQPDVNIDS
LEKLSHYWEDVRKYYAPFESGMNAPHTEVYMHEMPGGQYSNLQQQAKAVGLGDRFDEVKVMYRRVNDMFGDIVKVTPSSK
VVGDMALFMVQNHLTEQDVLERGHAMDFPGSVVEMFSGDLGQPYGGFPKELQKIILKGKEPLTVRPGELLEPVDFEALKE
ELFHKLGREVTIFDVVAYALYPKVFMDYEKVAELYGNVSVLDTPTFFYGMRLGEEIDVEIEQGKTLMVKLVSIGEPQPDG
NRVLYLEFNGQPREIIVKDESVKATVAQRVKGNRENPNHISATMPGTVIKVVVKEGDEVKKGDSMAITEAMKMETTVQAP
FNGKVKKVYVNDGDAIQTGDLLIELDH

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1146, Percent_Identity=50.5235602094241, Blast_Score=1135, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1146, Percent_Identity=50.5235602094241, Blast_Score=1135, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1146, Percent_Identity=50.5235602094241, Blast_Score=1135, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=464, Percent_Identity=42.6724137931034, Blast_Score=388, Evalue=1e-107,
Organism=Homo sapiens, GI189095269, Length=464, Percent_Identity=42.0258620689655, Blast_Score=360, Evalue=3e-99,
Organism=Homo sapiens, GI65506442, Length=456, Percent_Identity=42.5438596491228, Blast_Score=359, Evalue=1e-98,
Organism=Homo sapiens, GI295821183, Length=456, Percent_Identity=42.5438596491228, Blast_Score=358, Evalue=1e-98,
Organism=Homo sapiens, GI134142062, Length=509, Percent_Identity=31.434184675835, Blast_Score=239, Evalue=8e-63,
Organism=Homo sapiens, GI38679960, Length=508, Percent_Identity=32.0866141732283, Blast_Score=239, Evalue=1e-62,
Organism=Homo sapiens, GI38679977, Length=508, Percent_Identity=32.0866141732283, Blast_Score=239, Evalue=1e-62,
Organism=Homo sapiens, GI38679967, Length=508, Percent_Identity=32.0866141732283, Blast_Score=239, Evalue=1e-62,
Organism=Homo sapiens, GI38679974, Length=508, Percent_Identity=32.0866141732283, Blast_Score=239, Evalue=1e-62,
Organism=Homo sapiens, GI38679971, Length=508, Percent_Identity=32.0866141732283, Blast_Score=239, Evalue=2e-62,
Organism=Escherichia coli, GI1789654, Length=449, Percent_Identity=46.3251670378619, Blast_Score=390, Evalue=1e-109,
Organism=Escherichia coli, GI1786216, Length=365, Percent_Identity=22.7397260273973, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562816, Length=1150, Percent_Identity=50.3478260869565, Blast_Score=1134, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17567343, Length=470, Percent_Identity=42.7659574468085, Blast_Score=357, Evalue=3e-98,
Organism=Caenorhabditis elegans, GI71987519, Length=462, Percent_Identity=42.8571428571429, Blast_Score=349, Evalue=5e-96,
Organism=Caenorhabditis elegans, GI71997168, Length=438, Percent_Identity=30.365296803653, Blast_Score=200, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI71997163, Length=438, Percent_Identity=30.365296803653, Blast_Score=200, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI133931226, Length=497, Percent_Identity=29.1750503018109, Blast_Score=199, Evalue=7e-51,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1157, Percent_Identity=49.1789109766638, Blast_Score=1094, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1157, Percent_Identity=49.438202247191, Blast_Score=1090, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=448, Percent_Identity=38.3928571428571, Blast_Score=306, Evalue=2e-83,
Organism=Saccharomyces cerevisiae, GI6323863, Length=437, Percent_Identity=33.8672768878719, Blast_Score=225, Evalue=3e-59,
Organism=Saccharomyces cerevisiae, GI6324343, Length=512, Percent_Identity=29.8828125, Blast_Score=222, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6322331, Length=298, Percent_Identity=23.1543624161074, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24652212, Length=1144, Percent_Identity=51.0489510489511, Blast_Score=1144, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1144, Percent_Identity=51.0489510489511, Blast_Score=1144, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1144, Percent_Identity=51.0489510489511, Blast_Score=1144, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1144, Percent_Identity=51.0489510489511, Blast_Score=1144, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1144, Percent_Identity=51.0489510489511, Blast_Score=1144, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1161, Percent_Identity=50.5598621877692, Blast_Score=1139, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1161, Percent_Identity=50.5598621877692, Blast_Score=1139, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1161, Percent_Identity=50.5598621877692, Blast_Score=1139, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1161, Percent_Identity=50.5598621877692, Blast_Score=1139, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1161, Percent_Identity=50.5598621877692, Blast_Score=1139, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=510, Percent_Identity=40.1960784313725, Blast_Score=370, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24651759, Length=467, Percent_Identity=39.4004282655246, Blast_Score=327, Evalue=4e-89,
Organism=Drosophila melanogaster, GI161076409, Length=504, Percent_Identity=31.3492063492063, Blast_Score=239, Evalue=7e-63,
Organism=Drosophila melanogaster, GI161076407, Length=504, Percent_Identity=31.3492063492063, Blast_Score=239, Evalue=9e-63,
Organism=Drosophila melanogaster, GI24586460, Length=504, Percent_Identity=31.3492063492063, Blast_Score=239, Evalue=9e-63,
Organism=Drosophila melanogaster, GI24586458, Length=504, Percent_Identity=31.3492063492063, Blast_Score=239, Evalue=9e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 128428; Mature: 128297

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLQRIQKVLVANRGEIAIRVFRACSELGLKTVAIYSKEDSGSYHRYKADESYLVGEGK
CCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEECCCCEEECCCC
KPIDAYLDIEGIIEIAKSNHVDAIHPGYGFLSENIQFAKRCEEEGIIFIGPKSKHLDMFG
CCHHHHCCHHHHHHHHHCCCCCEECCCCCHHHHCHHHHHHHCCCCEEEECCCCCCHHHHH
DKVKARTQAQLAQIPVIPGSDGPVNSLEEVEKFAEKYDYPIIIKASLGGGGRGMRIVRTS
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECH
EELGESYNRAKSEAKAAFGNDEVYVEKFVEKPKHIEVQILADEEGNVVHLYERDCSVQRR
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEEECCCCCEEEEECCCCHHHHH
HQKVVEIAPSVSLSDDLRQRICDAAVKLTKNVNYLNAGTVEFLVKDDEFYFIEVNPRVQV
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEECCCEEEEEEECCCEEEEEECCCEEE
EHTITEMITGVDIVQSQILIADGHALHSKMVGVPKQEEVVVHGFAIQSRVTTEDPLNNFM
HHHHHHHHHHHHHHHCEEEEECCHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCHHHCC
PDTGKIMAYRSGGGFGVRLDTGNSFQGAVITPYYDSLLVKVTTWALTFEQAAAKMERNLK
CCCCCEEEEECCCCEEEEEECCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHCHH
EFRIRGIKTNIPFLENVVKHKNFLSGEYDTSFIDASPELFLFPKRKDRGTKMLNYIGTVT
HHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEECCCCCEEEEECCCCCHHHHHHHHEEEE
VNGFPGVGKKEKPIFPDARIPCLKHSEPIQNGTKQILDERGADGLVKWVQDQKRVLLTDT
ECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEC
TFRDAHQSLLATRIRTKDLHQIAEPTARMLPNLFSAEMWGGATFDVAYRFLKEDPWERLL
CHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHH
DLREKMPNVLFQMLLRSSNAVGYKNYPDNLIQKFVECSAQAGIDVFRIFDSLNWVEGMRV
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHH
AIDAVRDTGKIAEATMCYTGDIHDPLRSKYDLNYYKNLAKELEASGAHILGIKDMAGLLK
HHHHHHCCCCHHHEEEEEECCCCHHHHHCCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHC
PNAAYDLVSALKETVSIPIHLHTHDTSGNGILTYTKAIEAGVDIVDVAVSSMAGQTSQPS
CCHHHHHHHHHHHHHEEEEEEEECCCCCCEEEEEHHHHHCCCHHHHHHHHHHCCCCCCCC
ANTLYYALGGNERQPDVNIDSLEKLSHYWEDVRKYYAPFESGMNAPHTEVYMHEMPGGQY
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCH
SNLQQQAKAVGLGDRFDEVKVMYRRVNDMFGDIVKVTPSSKVVGDMALFMVQNHLTEQDV
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHCCCHHHH
LERGHAMDFPGSVVEMFSGDLGQPYGGFPKELQKIILKGKEPLTVRPGELLEPVDFEALK
HHCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCEECCCCCCCCCCHHHHH
EELFHKLGREVTIFDVVAYALYPKVFMDYEKVAELYGNVSVLDTPTFFYGMRLGEEIDVE
HHHHHHHCCCEEHHHHHHHHHHHHHHHCHHHHHHHHCCCEEEECCHHHHHHHCCCEEEEE
IEQGKTLMVKLVSIGEPQPDGNRVLYLEFNGQPREIIVKDESVKATVAQRVKGNRENPNH
ECCCCEEEEEEEECCCCCCCCCEEEEEEECCCCCEEEEECCCHHHHHHHHHCCCCCCCCE
ISATMPGTVIKVVVKEGDEVKKGDSMAITEAMKMETTVQAPFNGKVKKVYVNDGDAIQTG
EEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHEEEECCCCCCEEEEEECCCCEEEEC
DLLIELDH
CEEEEECC
>Mature Secondary Structure 
TKLQRIQKVLVANRGEIAIRVFRACSELGLKTVAIYSKEDSGSYHRYKADESYLVGEGK
CHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEECCCCEEECCCC
KPIDAYLDIEGIIEIAKSNHVDAIHPGYGFLSENIQFAKRCEEEGIIFIGPKSKHLDMFG
CCHHHHCCHHHHHHHHHCCCCCEECCCCCHHHHCHHHHHHHCCCCEEEECCCCCCHHHHH
DKVKARTQAQLAQIPVIPGSDGPVNSLEEVEKFAEKYDYPIIIKASLGGGGRGMRIVRTS
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECH
EELGESYNRAKSEAKAAFGNDEVYVEKFVEKPKHIEVQILADEEGNVVHLYERDCSVQRR
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEEECCCCCEEEEECCCCHHHHH
HQKVVEIAPSVSLSDDLRQRICDAAVKLTKNVNYLNAGTVEFLVKDDEFYFIEVNPRVQV
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEECCCEEEEEEECCCEEEEEECCCEEE
EHTITEMITGVDIVQSQILIADGHALHSKMVGVPKQEEVVVHGFAIQSRVTTEDPLNNFM
HHHHHHHHHHHHHHHCEEEEECCHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCHHHCC
PDTGKIMAYRSGGGFGVRLDTGNSFQGAVITPYYDSLLVKVTTWALTFEQAAAKMERNLK
CCCCCEEEEECCCCEEEEEECCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHCHH
EFRIRGIKTNIPFLENVVKHKNFLSGEYDTSFIDASPELFLFPKRKDRGTKMLNYIGTVT
HHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEECCCCCEEEEECCCCCHHHHHHHHEEEE
VNGFPGVGKKEKPIFPDARIPCLKHSEPIQNGTKQILDERGADGLVKWVQDQKRVLLTDT
ECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEC
TFRDAHQSLLATRIRTKDLHQIAEPTARMLPNLFSAEMWGGATFDVAYRFLKEDPWERLL
CHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHH
DLREKMPNVLFQMLLRSSNAVGYKNYPDNLIQKFVECSAQAGIDVFRIFDSLNWVEGMRV
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHH
AIDAVRDTGKIAEATMCYTGDIHDPLRSKYDLNYYKNLAKELEASGAHILGIKDMAGLLK
HHHHHHCCCCHHHEEEEEECCCCHHHHHCCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHC
PNAAYDLVSALKETVSIPIHLHTHDTSGNGILTYTKAIEAGVDIVDVAVSSMAGQTSQPS
CCHHHHHHHHHHHHHEEEEEEEECCCCCCEEEEEHHHHHCCCHHHHHHHHHHCCCCCCCC
ANTLYYALGGNERQPDVNIDSLEKLSHYWEDVRKYYAPFESGMNAPHTEVYMHEMPGGQY
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCH
SNLQQQAKAVGLGDRFDEVKVMYRRVNDMFGDIVKVTPSSKVVGDMALFMVQNHLTEQDV
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHCCCHHHH
LERGHAMDFPGSVVEMFSGDLGQPYGGFPKELQKIILKGKEPLTVRPGELLEPVDFEALK
HHCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCEECCCCCCCCCCHHHHH
EELFHKLGREVTIFDVVAYALYPKVFMDYEKVAELYGNVSVLDTPTFFYGMRLGEEIDVE
HHHHHHHCCCEEHHHHHHHHHHHHHHHCHHHHHHHHCCCEEEECCHHHHHHHCCCEEEEE
IEQGKTLMVKLVSIGEPQPDGNRVLYLEFNGQPREIIVKDESVKATVAQRVKGNRENPNH
ECCCCEEEEEEEECCCCCCCCCEEEEEEECCCCCEEEEECCCHHHHHHHHHCCCCCCCCE
ISATMPGTVIKVVVKEGDEVKKGDSMAITEAMKMETTVQAPFNGKVKKVYVNDGDAIQTG
EEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHEEEECCCCCCEEEEEECCCCEEEEC
DLLIELDH
CEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]