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The map label for this gene is ymfH [H]

Identifier: 218235990

GI number: 218235990

Start: 3801467

End: 3802753

Strand: Reverse

Name: ymfH [H]

Synonym: BCB4264_A3885

Alternate gene names: 218235990

Gene position: 3802753-3801467 (Counterclockwise)

Preceding gene: 218232950

Following gene: 218235728

Centisome position: 70.17

GC content: 32.4

Gene sequence:

>1287_bases
ATGGAGAAAATTGTTTATGAGCAATTAAAAGAAACACTCTATTATGAAAAACTTCCTAATGGATTAGATGTATATGTTTT
ACCGAAACAAGGATTTAATAAAACATTTGCGACGTTTACGACGAAATATGGTTCTGTAGATAATACATTTGTACCATTAG
GGAAAGAAGAAATGATTCGTGTGCCTGATGGAATTGCACATTTTCTTGAGCATAAATTATTTGAAAAAGAAGATCACGAT
GCTTTCCAATTGTTTAGTAAACAAGGAGCATCGGCAAATGCTTTTACATCCTTTACACGAACAGCTTACCTTTTTTCATG
TACTTCAAACGTAGAACAAAATTTAAATACATTGCTAAACTTCGTGCAAGAGCCTTATTTCTCTGAAAAAACGGTTGAAA
AAGAGAAGGGGATAATTGGGCAAGAAATTCAAATGTATCAAGATAACCCAGATTGGCGTTTGTACTTCGGGTTAATTGAT
AGCTTGTTTGTAAAACACCCAATTAAAATTGATATTGCAGGGACAATCGAATCTATTAGTAAAATTACGAAAGATTTATT
GTATGAATGTTATGAAACATTTTATCATCCGAGCAATATGTTATTATTTGTTGTGGGTGCAATTGATCCAGAGAAAACAA
TGGATTTAGTACGTGAAAATCAAGCGAAAAAAGATTATAAAAACCAGCCAGAAATTGTGCGTTCATTTGAAGAAGAACCA
AATGAGGTAAATGAAAAGAAAAAAATTATTTCAATGCCTGTGCAAACACCGAAATGTTTAGTTGGTATTAAAGCGACTAA
TTTAAAGGAAAAGGGGCAAGCGCTTTTAAAACAAGAAATTGCGCTTACGTTACTCTTAGATTATTTATTTGGAAAAAGTT
CTGTTCATTACGAAACTTTATATAATGAAGGGCTTATTGATGATTCATTCTCGTATGACTATACAGAAGAAAATAACTTC
GGTTTTGCAATGGTTGGCGGTGATACGAAACAACCTGATGAATTGGCAAATCGTTTAAAAGATATTTTATTAAAAACAGA
TTATGATCAATTAGATGCGGCGGCATTAGAACGAGTGAAGAAAAAGAAAATTGGTGGTTTTTTACGCTCGTTGAATTCAC
CAGAATATATTGCAAATCAATTTACACGATACGCGTTTAATGAATCTAGCCTATTTGACGCATTGACTGTATTAGAAGGA
CTAACCGTTCAAGACTTACAAGAAGTAGCGAAATTATTGTTATCAGAAGACAAAATGAGTATTTGTCAGGTGTTACCGAA
AAAATAA

Upstream 100 bases:

>100_bases
TACAGGTATAGAAAGTGTGACGAAAGAAGAAATTGTAAAAGTTGCTAAAAATATTGAACTAGATACAATTTACTTTTTAC
AAGGAACGGAGGGAGAGTAA

Downstream 100 bases:

>100_bases
AATTAAAAAGATACCCTCATCTTATCATTGAAAAATTGTAAGATGAGGGTATTATTTAGTTATGTGAAAATTGAACTTGT
AGAGATAAGAGAGGGACTTT

Product: zinc protease, insulinase family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MEKIVYEQLKETLYYEKLPNGLDVYVLPKQGFNKTFATFTTKYGSVDNTFVPLGKEEMIRVPDGIAHFLEHKLFEKEDHD
AFQLFSKQGASANAFTSFTRTAYLFSCTSNVEQNLNTLLNFVQEPYFSEKTVEKEKGIIGQEIQMYQDNPDWRLYFGLID
SLFVKHPIKIDIAGTIESISKITKDLLYECYETFYHPSNMLLFVVGAIDPEKTMDLVRENQAKKDYKNQPEIVRSFEEEP
NEVNEKKKIISMPVQTPKCLVGIKATNLKEKGQALLKQEIALTLLLDYLFGKSSVHYETLYNEGLIDDSFSYDYTEENNF
GFAMVGGDTKQPDELANRLKDILLKTDYDQLDAAALERVKKKKIGGFLRSLNSPEYIANQFTRYAFNESSLFDALTVLEG
LTVQDLQEVAKLLLSEDKMSICQVLPKK

Sequences:

>Translated_428_residues
MEKIVYEQLKETLYYEKLPNGLDVYVLPKQGFNKTFATFTTKYGSVDNTFVPLGKEEMIRVPDGIAHFLEHKLFEKEDHD
AFQLFSKQGASANAFTSFTRTAYLFSCTSNVEQNLNTLLNFVQEPYFSEKTVEKEKGIIGQEIQMYQDNPDWRLYFGLID
SLFVKHPIKIDIAGTIESISKITKDLLYECYETFYHPSNMLLFVVGAIDPEKTMDLVRENQAKKDYKNQPEIVRSFEEEP
NEVNEKKKIISMPVQTPKCLVGIKATNLKEKGQALLKQEIALTLLLDYLFGKSSVHYETLYNEGLIDDSFSYDYTEENNF
GFAMVGGDTKQPDELANRLKDILLKTDYDQLDAAALERVKKKKIGGFLRSLNSPEYIANQFTRYAFNESSLFDALTVLEG
LTVQDLQEVAKLLLSEDKMSICQVLPKK
>Mature_428_residues
MEKIVYEQLKETLYYEKLPNGLDVYVLPKQGFNKTFATFTTKYGSVDNTFVPLGKEEMIRVPDGIAHFLEHKLFEKEDHD
AFQLFSKQGASANAFTSFTRTAYLFSCTSNVEQNLNTLLNFVQEPYFSEKTVEKEKGIIGQEIQMYQDNPDWRLYFGLID
SLFVKHPIKIDIAGTIESISKITKDLLYECYETFYHPSNMLLFVVGAIDPEKTMDLVRENQAKKDYKNQPEIVRSFEEEP
NEVNEKKKIISMPVQTPKCLVGIKATNLKEKGQALLKQEIALTLLLDYLFGKSSVHYETLYNEGLIDDSFSYDYTEENNF
GFAMVGGDTKQPDELANRLKDILLKTDYDQLDAAALERVKKKKIGGFLRSLNSPEYIANQFTRYAFNESSLFDALTVLEG
LTVQDLQEVAKLLLSEDKMSICQVLPKK

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Escherichia coli, GI1787770, Length=240, Percent_Identity=26.25, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71999683, Length=427, Percent_Identity=23.8875878220141, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 49092; Mature: 49092

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKIVYEQLKETLYYEKLPNGLDVYVLPKQGFNKTFATFTTKYGSVDNTFVPLGKEEMIR
CCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHEE
VPDGIAHFLEHKLFEKEDHDAFQLFSKQGASANAFTSFTRTAYLFSCTSNVEQNLNTLLN
CCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHEEHHHHHHHHHHHHHHH
FVQEPYFSEKTVEKEKGIIGQEIQMYQDNPDWRLYFGLIDSLFVKHPIKIDIAGTIESIS
HHHCCCCCHHHHHHHCCCCCCHHHEECCCCCCEEHHHHHHHHHHCCCEEEEECHHHHHHH
KITKDLLYECYETFYHPSNMLLFVVGAIDPEKTMDLVRENQAKKDYKNQPEIVRSFEEEP
HHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC
NEVNEKKKIISMPVQTPKCLVGIKATNLKEKGQALLKQEIALTLLLDYLFGKSSVHYETL
HHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
YNEGLIDDSFSYDYTEENNFGFAMVGGDTKQPDELANRLKDILLKTDYDQLDAAALERVK
HCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
KKKIGGFLRSLNSPEYIANQFTRYAFNESSLFDALTVLEGLTVQDLQEVAKLLLSEDKMS
HHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHH
ICQVLPKK
HHHHCCCC
>Mature Secondary Structure
MEKIVYEQLKETLYYEKLPNGLDVYVLPKQGFNKTFATFTTKYGSVDNTFVPLGKEEMIR
CCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHEE
VPDGIAHFLEHKLFEKEDHDAFQLFSKQGASANAFTSFTRTAYLFSCTSNVEQNLNTLLN
CCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHEEHHHHHHHHHHHHHHH
FVQEPYFSEKTVEKEKGIIGQEIQMYQDNPDWRLYFGLIDSLFVKHPIKIDIAGTIESIS
HHHCCCCCHHHHHHHCCCCCCHHHEECCCCCCEEHHHHHHHHHHCCCEEEEECHHHHHHH
KITKDLLYECYETFYHPSNMLLFVVGAIDPEKTMDLVRENQAKKDYKNQPEIVRSFEEEP
HHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC
NEVNEKKKIISMPVQTPKCLVGIKATNLKEKGQALLKQEIALTLLLDYLFGKSSVHYETL
HHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
YNEGLIDDSFSYDYTEENNFGFAMVGGDTKQPDELANRLKDILLKTDYDQLDAAALERVK
HCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
KKKIGGFLRSLNSPEYIANQFTRYAFNESSLFDALTVLEGLTVQDLQEVAKLLLSEDKMS
HHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHH
ICQVLPKK
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]