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The map label for this gene is nsr [H]

Identifier: 218235755

GI number: 218235755

Start: 3337405

End: 3338097

Strand: Reverse

Name: nsr [H]

Synonym: BCB4264_A3454

Alternate gene names: 218235755

Gene position: 3338097-3337405 (Counterclockwise)

Preceding gene: 218232849

Following gene: 218235894

Centisome position: 61.6

GC content: 30.74

Gene sequence:

>693_bases
ATGAAGAAAGTATGTAATTCTATTAAATTAGCAGAGTATATGAAGAAAAATAATATTGATTCATTTTTTAGTCATGATAT
GAAGCCATATATGGAACTTATATTTTTTAAAAAGAATGAGTTTATTTGTAGAGAAAATGAAGAGATAGATTATTTATATT
TCTTTGTTGAAGGAAAAGCGAAAGCGTTTAACACATTAAGTAACGGGAAATCCGTATTACTGTGTTTTTATGATAGTTTG
CAGTTACTTGGAGATGTGGAGTTAATTCATTCCCAAAGGATTACTTCAAATGTACAAGTAATGGCAGATTCATATTGTGT
TGGTTTACCATTAGGAAAAGTGAGAAATCAGCTATTTCATGATGCGAAATTTTTAAGATGTATTTGTGGATCGTTAGCAC
ATAAGTTAAATCGACTTTCAAAAAATAGTACAATTAATTTATTGTATCCGCTTGAAAATAGACTTGCGAGTTACATGTTA
GCAGCAGGGGAACGAGCAGTTCAGCATGAAAATAGAATTGTATTTAGTGGGAATTTAACGGAAATAGCGGAATTGTTAGG
AACGAGCTATCGGCATTTGTTGCGAACATTAAATATTTTTTGTGATAAAGAGATAATAAAGAAGAACGATGGATGCTATG
AAGTAGTAAACGTGGATGTTTTGAGAGAATTGGCAGCAGATGTTTATAAATAG

Upstream 100 bases:

>100_bases
TGACTGTATCATGCTGAAATTGTGTATTGTTATGACATATGTCATAGTGGAAGAAGAAAATTTTGATTACAATGGGGATG
AGTTGTAAAGGTGGGGAACT

Downstream 100 bases:

>100_bases
GAGGAGAGTATAAATGATAACACCTATATTTAGAATTTTTGATATTGAAAAAGCAAAACTATTTTACTTAGGTTTTTTAG
GATTTAAACTGGATTGGGAA

Product: cyclic nucleotide-binding domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MKKVCNSIKLAEYMKKNNIDSFFSHDMKPYMELIFFKKNEFICRENEEIDYLYFFVEGKAKAFNTLSNGKSVLLCFYDSL
QLLGDVELIHSQRITSNVQVMADSYCVGLPLGKVRNQLFHDAKFLRCICGSLAHKLNRLSKNSTINLLYPLENRLASYML
AAGERAVQHENRIVFSGNLTEIAELLGTSYRHLLRTLNIFCDKEIIKKNDGCYEVVNVDVLRELAADVYK

Sequences:

>Translated_230_residues
MKKVCNSIKLAEYMKKNNIDSFFSHDMKPYMELIFFKKNEFICRENEEIDYLYFFVEGKAKAFNTLSNGKSVLLCFYDSL
QLLGDVELIHSQRITSNVQVMADSYCVGLPLGKVRNQLFHDAKFLRCICGSLAHKLNRLSKNSTINLLYPLENRLASYML
AAGERAVQHENRIVFSGNLTEIAELLGTSYRHLLRTLNIFCDKEIIKKNDGCYEVVNVDVLRELAADVYK
>Mature_230_residues
MKKVCNSIKLAEYMKKNNIDSFFSHDMKPYMELIFFKKNEFICRENEEIDYLYFFVEGKAKAFNTLSNGKSVLLCFYDSL
QLLGDVELIHSQRITSNVQVMADSYCVGLPLGKVRNQLFHDAKFLRCICGSLAHKLNRLSKNSTINLLYPLENRLASYML
AAGERAVQHENRIVFSGNLTEIAELLGTSYRHLLRTLNIFCDKEIIKKNDGCYEVVNVDVLRELAADVYK

Specific function: Transcription regulator involved in mid-term, stationary-phase viability under nitrogen starvation. Might control expression of the salvage pathways or in some other way repress the recycling of nucleobases to nucleic acids and enhance their use as genera

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788487, Length=215, Percent_Identity=31.1627906976744, Blast_Score=112, Evalue=3e-26,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR012318
- InterPro:   IPR014710 [H]

Pfam domain/function: PF00027 cNMP_binding [H]

EC number: NA

Molecular weight: Translated: 26506; Mature: 26506

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVCNSIKLAEYMKKNNIDSFFSHDMKPYMELIFFKKNEFICRENEEIDYLYFFVEGKA
CCHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHCCCCEEECCCCCCEEEEEEEECCH
KAFNTLSNGKSVLLCFYDSLQLLGDVELIHSQRITSNVQVMADSYCVGLPLGKVRNQLFH
HHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCHHEEECCEEECCCHHHHHHHHHH
DAKFLRCICGSLAHKLNRLSKNSTINLLYPLENRLASYMLAAGERAVQHENRIVFSGNLT
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCEEEEECCHH
EIAELLGTSYRHLLRTLNIFCDKEIIKKNDGCYEVVNVDVLRELAADVYK
HHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKVCNSIKLAEYMKKNNIDSFFSHDMKPYMELIFFKKNEFICRENEEIDYLYFFVEGKA
CCHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHCCCCEEECCCCCCEEEEEEEECCH
KAFNTLSNGKSVLLCFYDSLQLLGDVELIHSQRITSNVQVMADSYCVGLPLGKVRNQLFH
HHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCHHEEECCEEECCCHHHHHHHHHH
DAKFLRCICGSLAHKLNRLSKNSTINLLYPLENRLASYMLAAGERAVQHENRIVFSGNLT
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCEEEEECCHH
EIAELLGTSYRHLLRTLNIFCDKEIIKKNDGCYEVVNVDVLRELAADVYK
HHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]