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The map label for this gene is acyII [H]

Identifier: 218235719

GI number: 218235719

Start: 3155458

End: 3157848

Strand: Reverse

Name: acyII [H]

Synonym: BCB4264_A3266

Alternate gene names: 218235719

Gene position: 3157848-3155458 (Counterclockwise)

Preceding gene: 218235097

Following gene: 218231179

Centisome position: 58.27

GC content: 38.81

Gene sequence:

>2391_bases
ATGGAAGTCGTTATAAAGAAGAAACGAAAAAGGGGAAAAAGAATTTTTATTTGGGCTAGTAGTATCGTTCTTTTGTTAGT
TATTTCCGCTGCGATTTTTTTGAACATATATACGCTGAAATCTATGCCAAAGATAGATGGAACGATAAAGCTAGAGGATT
TACAACAGGCTGTTACGGTGAAGCGTGATAGTAAAGGTGTACCGCATATTAAATCGGAAAATGCACATGATTTATATTTT
TCACAAGGATATGTGCAAGCGCAAGATCGTTTGTTTCAAATGGATTTAAGTAGAAGACAAGCGTCTGGTATGTTAAGTGA
AGTTGTTGGGGAAGCAGCTGTTGATCGAGATAAATTGTTTCGAACACTCGGTTTACGGCGAGCTGCCGAAGCTTCAGTTA
GTCAATATGATGGAGAAGCGAAATATGCCCTGCAGTCATTTGCTGATGGGGTGAACGCTTTTATACGTGAGGCGAAAGAG
GAAAAGAAATTACCAGTTGAGTTTACTATATTAGGTTATGAACCTGCTGAGTGGTCAATTGTTGATACTTTAACAATCGG
GAAGTATATGGCGTTTGACTTAGGAGGACATTGGCACGGACAGGCATTTCGATATTGGGCGCTGAAAAATCTTCCGAAAG
AGCAAGCGAATGAGCTATTTCCTGCATATCCGAAAGATGCCCCTAGATTGCTAGCTGAACTGAAAAATACAAATGTGGAC
GTAGCACAAAGTTTTTCAAAAACGATAATTCCGCCGGAGTTTAACGGTAGTAATAACTGGGTTGTGAGCGGTGAGAAGAG
TGCGTCAGGTAAGCCAATTTTAGCAGATGATCCTCATTTATCTCTTGCGACGCCTTCTATTTGGTATCAAACGAGACTTG
AAATGAAAGGTTTAAATGTGAGTGGCGTTATTTTCGCTGGAGTACCAGGTGTTATATTAGGACACAATGACAAAATAGCA
TGGGGTGTTACGAATACAGGGCCTGATGTGCAAGATTTATATATTGAGAAGAGAAATCCTAATAATGAAAATGAATTTCT
GTATAACAATAAATGGGAAAAAGCTACCGTTGTAGACGAGTCTATTAAAGTAAAAGGCGGGAAGACAATTCCTTATAACG
TTACGATTACGAGGCATGGGCCAGTAATTTCAGAGTTTGCGGATAAGGGGAAGGAGAAAACGAAAACAGTATTCTCTTTA
AAGTGGACAGCTTTAGAACCGTCAGCTGAGTTAAAAGCTGTATTAAATATGAACAAAGCAAAAGACTGGAATGAGTTTGA
AACCGCTCTTCAAGATTTTCATACACCAACCCAAAACTTTGTGTTTGCATCAAACGACGGCACAATTGCTTATAAAGCGA
ATGGAAATATACCAGTGCGTAAAAAAGGTGATGGTAGCTTACCTGTTCCAGGATGGACAGATGAATATGAATGGGAAGGG
TATATCCCGTTTGATCAACTTCCAAAAGTAATTAATCCAAAACAAGGGTTTATTTCAACTGCGAATAATAAAATTGTTGA
TGATGATTATCCGTATCATATTAGCAATACGTGGGCGCAGCCATATAGGCAAATGCGTATTCAAGAATTTTTGCAAGAGA
AGGAAAAGTATACGGTGAAAGATTTAGAAGAGTTACAGATGGATCAAAAGAATTTATATGGGAAAGAGTTTACTCCTATA
TTTTTAAAAGAGTTAAATAAAGCATCTTTAAATGAGGTAGAGAAAGAAGGCGTAGACCAATTAACAAAGTGGAATTTTTA
CGATAGTAAAGATGAAGCGGCACCATTAATATTCCATTTGTTAATGAAAGAGATTTCAAATACGTTATTTTCAAAAGAAA
TACCGAAAGATGTACTGGAGTTATTTGAAGGGAAGTCACAAGTTGTTGATGAATTGATTCGAAAAGAAGTAGCGGGAGAA
AATAGCGTTTGGTTTACGAAGTACGGAGGTTTCACAAAAGTTGTGCATACATCGTACGAGAATGTAATGAAGAAATTGCA
GAAGGAATATGGACCCGATGTTGGAGAGTGGAAGTGGGGCGATTACCATCAACTCGCTTTTACACATCCCATTTCGAAAT
CATCGAGTATGTTAGCATTACTCGCTTTTAATCGTGAGAAGCCAGTTCCAATTGGTGGGAGCCAAGTTACCGTGCAAGCA
GCGAGTTACGGCGAAAACGGCATTGTAAATCACGGGGCGTCTTGGAGATTCATTATTGATACGAAAGATATGTCAAACGG
TTATCATATCGTAGGGCCAGGACAGTCGGGCCATTTTAGAAGCGATTGGTATCATGATCAAATAGATGATTGGGTAAATG
GCACGTATCATACGACTACATTGAATACGGAGGGGATAGAGGGGAAGGTATTAACTTTGCAGCCGAAGTGA

Upstream 100 bases:

>100_bases
AGTATTTGGTTCGTATGATCCATAGTTTGGATAAGGATTTTTTCTAGTCTAAAAGGTTCTTTTACTATAGAAGCGAATAG
TGTGAGAAAGGGGTGGTTAT

Downstream 100 bases:

>100_bases
TAGTCAGTTCTTATTTGCAGATGGCCCAGCTTTATGAGGTAATACTCCTTCGGCTAATGAAAGTTTTGCTTTATACAAGA
GACTCTTACGATTGTAAGAG

Product: beta-lactam antibiotic acylase family protein

Products: NA

Alternate protein names: Cephalosporin acylase II; Penicillin acylase II; Penicillin amidase II; Penicillin acylase II small subunit; Penicillin acylase II large subunit [H]

Number of amino acids: Translated: 796; Mature: 796

Protein sequence:

>796_residues
MEVVIKKKRKRGKRIFIWASSIVLLLVISAAIFLNIYTLKSMPKIDGTIKLEDLQQAVTVKRDSKGVPHIKSENAHDLYF
SQGYVQAQDRLFQMDLSRRQASGMLSEVVGEAAVDRDKLFRTLGLRRAAEASVSQYDGEAKYALQSFADGVNAFIREAKE
EKKLPVEFTILGYEPAEWSIVDTLTIGKYMAFDLGGHWHGQAFRYWALKNLPKEQANELFPAYPKDAPRLLAELKNTNVD
VAQSFSKTIIPPEFNGSNNWVVSGEKSASGKPILADDPHLSLATPSIWYQTRLEMKGLNVSGVIFAGVPGVILGHNDKIA
WGVTNTGPDVQDLYIEKRNPNNENEFLYNNKWEKATVVDESIKVKGGKTIPYNVTITRHGPVISEFADKGKEKTKTVFSL
KWTALEPSAELKAVLNMNKAKDWNEFETALQDFHTPTQNFVFASNDGTIAYKANGNIPVRKKGDGSLPVPGWTDEYEWEG
YIPFDQLPKVINPKQGFISTANNKIVDDDYPYHISNTWAQPYRQMRIQEFLQEKEKYTVKDLEELQMDQKNLYGKEFTPI
FLKELNKASLNEVEKEGVDQLTKWNFYDSKDEAAPLIFHLLMKEISNTLFSKEIPKDVLELFEGKSQVVDELIRKEVAGE
NSVWFTKYGGFTKVVHTSYENVMKKLQKEYGPDVGEWKWGDYHQLAFTHPISKSSSMLALLAFNREKPVPIGGSQVTVQA
ASYGENGIVNHGASWRFIIDTKDMSNGYHIVGPGQSGHFRSDWYHDQIDDWVNGTYHTTTLNTEGIEGKVLTLQPK

Sequences:

>Translated_796_residues
MEVVIKKKRKRGKRIFIWASSIVLLLVISAAIFLNIYTLKSMPKIDGTIKLEDLQQAVTVKRDSKGVPHIKSENAHDLYF
SQGYVQAQDRLFQMDLSRRQASGMLSEVVGEAAVDRDKLFRTLGLRRAAEASVSQYDGEAKYALQSFADGVNAFIREAKE
EKKLPVEFTILGYEPAEWSIVDTLTIGKYMAFDLGGHWHGQAFRYWALKNLPKEQANELFPAYPKDAPRLLAELKNTNVD
VAQSFSKTIIPPEFNGSNNWVVSGEKSASGKPILADDPHLSLATPSIWYQTRLEMKGLNVSGVIFAGVPGVILGHNDKIA
WGVTNTGPDVQDLYIEKRNPNNENEFLYNNKWEKATVVDESIKVKGGKTIPYNVTITRHGPVISEFADKGKEKTKTVFSL
KWTALEPSAELKAVLNMNKAKDWNEFETALQDFHTPTQNFVFASNDGTIAYKANGNIPVRKKGDGSLPVPGWTDEYEWEG
YIPFDQLPKVINPKQGFISTANNKIVDDDYPYHISNTWAQPYRQMRIQEFLQEKEKYTVKDLEELQMDQKNLYGKEFTPI
FLKELNKASLNEVEKEGVDQLTKWNFYDSKDEAAPLIFHLLMKEISNTLFSKEIPKDVLELFEGKSQVVDELIRKEVAGE
NSVWFTKYGGFTKVVHTSYENVMKKLQKEYGPDVGEWKWGDYHQLAFTHPISKSSSMLALLAFNREKPVPIGGSQVTVQA
ASYGENGIVNHGASWRFIIDTKDMSNGYHIVGPGQSGHFRSDWYHDQIDDWVNGTYHTTTLNTEGIEGKVLTLQPK
>Mature_796_residues
MEVVIKKKRKRGKRIFIWASSIVLLLVISAAIFLNIYTLKSMPKIDGTIKLEDLQQAVTVKRDSKGVPHIKSENAHDLYF
SQGYVQAQDRLFQMDLSRRQASGMLSEVVGEAAVDRDKLFRTLGLRRAAEASVSQYDGEAKYALQSFADGVNAFIREAKE
EKKLPVEFTILGYEPAEWSIVDTLTIGKYMAFDLGGHWHGQAFRYWALKNLPKEQANELFPAYPKDAPRLLAELKNTNVD
VAQSFSKTIIPPEFNGSNNWVVSGEKSASGKPILADDPHLSLATPSIWYQTRLEMKGLNVSGVIFAGVPGVILGHNDKIA
WGVTNTGPDVQDLYIEKRNPNNENEFLYNNKWEKATVVDESIKVKGGKTIPYNVTITRHGPVISEFADKGKEKTKTVFSL
KWTALEPSAELKAVLNMNKAKDWNEFETALQDFHTPTQNFVFASNDGTIAYKANGNIPVRKKGDGSLPVPGWTDEYEWEG
YIPFDQLPKVINPKQGFISTANNKIVDDDYPYHISNTWAQPYRQMRIQEFLQEKEKYTVKDLEELQMDQKNLYGKEFTPI
FLKELNKASLNEVEKEGVDQLTKWNFYDSKDEAAPLIFHLLMKEISNTLFSKEIPKDVLELFEGKSQVVDELIRKEVAGE
NSVWFTKYGGFTKVVHTSYENVMKKLQKEYGPDVGEWKWGDYHQLAFTHPISKSSSMLALLAFNREKPVPIGGSQVTVQA
ASYGENGIVNHGASWRFIIDTKDMSNGYHIVGPGQSGHFRSDWYHDQIDDWVNGTYHTTTLNTEGIEGKVLTLQPK

Specific function: Unknown

COG id: COG2366

COG function: function code R; Protein related to penicillin acylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S45 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014395
- InterPro:   IPR002692 [H]

Pfam domain/function: PF01804 Penicil_amidase [H]

EC number: =3.5.1.11 [H]

Molecular weight: Translated: 90086; Mature: 90086

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVVIKKKRKRGKRIFIWASSIVLLLVISAAIFLNIYTLKSMPKIDGTIKLEDLQQAVTV
CCCEEECHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHH
KRDSKGVPHIKSENAHDLYFSQGYVQAQDRLFQMDLSRRQASGMLSEVVGEAAVDRDKLF
HCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
RTLGLRRAAEASVSQYDGEAKYALQSFADGVNAFIREAKEEKKLPVEFTILGYEPAEWSI
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEE
VDTLTIGKYMAFDLGGHWHGQAFRYWALKNLPKEQANELFPAYPKDAPRLLAELKNTNVD
EEEEHHCCEEEEECCCCCCCCCEEEHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHCCCCH
VAQSFSKTIIPPEFNGSNNWVVSGEKSASGKPILADDPHLSLATPSIWYQTRLEMKGLNV
HHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCEECCCCCCEECCCCCEEEEEEEECCCCC
SGVIFAGVPGVILGHNDKIAWGVTNTGPDVQDLYIEKRNPNNENEFLYNNKWEKATVVDE
CEEEEECCCEEEEECCCEEEEECCCCCCCHHHEEEECCCCCCCCCEEECCCCCEEEEECC
SIKVKGGKTIPYNVTITRHGPVISEFADKGKEKTKTVFSLKWTALEPSAELKAVLNMNKA
CEEECCCCCCEEEEEEEECCCHHHHHHHCCHHHHCEEEEEEEEEECCCHHHHHHHCCCCC
KDWNEFETALQDFHTPTQNFVFASNDGTIAYKANGNIPVRKKGDGSLPVPGWTDEYEWEG
CCHHHHHHHHHHHCCCCCCEEEECCCCEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCC
YIPFDQLPKVINPKQGFISTANNKIVDDDYPYHISNTWAQPYRQMRIQEFLQEKEKYTVK
CCCHHHCCHHCCCCCCCEECCCCCEECCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCHH
DLEELQMDQKNLYGKEFTPIFLKELNKASLNEVEKEGVDQLTKWNFYDSKDEAAPLIFHL
HHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
LMKEISNTLFSKEIPKDVLELFEGKSQVVDELIRKEVAGENSVWFTKYGGFTKVVHTSYE
HHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHH
NVMKKLQKEYGPDVGEWKWGDYHQLAFTHPISKSSSMLALLAFNREKPVPIGGSQVTVQA
HHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCEEEEEE
ASYGENGIVNHGASWRFIIDTKDMSNGYHIVGPGQSGHFRSDWYHDQIDDWVNGTYHTTT
ECCCCCCCEECCCCEEEEEECCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHCCCEEEEE
LNTEGIEGKVLTLQPK
ECCCCCCCEEEEECCC
>Mature Secondary Structure
MEVVIKKKRKRGKRIFIWASSIVLLLVISAAIFLNIYTLKSMPKIDGTIKLEDLQQAVTV
CCCEEECHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHH
KRDSKGVPHIKSENAHDLYFSQGYVQAQDRLFQMDLSRRQASGMLSEVVGEAAVDRDKLF
HCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
RTLGLRRAAEASVSQYDGEAKYALQSFADGVNAFIREAKEEKKLPVEFTILGYEPAEWSI
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEE
VDTLTIGKYMAFDLGGHWHGQAFRYWALKNLPKEQANELFPAYPKDAPRLLAELKNTNVD
EEEEHHCCEEEEECCCCCCCCCEEEHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHCCCCH
VAQSFSKTIIPPEFNGSNNWVVSGEKSASGKPILADDPHLSLATPSIWYQTRLEMKGLNV
HHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCEECCCCCCEECCCCCEEEEEEEECCCCC
SGVIFAGVPGVILGHNDKIAWGVTNTGPDVQDLYIEKRNPNNENEFLYNNKWEKATVVDE
CEEEEECCCEEEEECCCEEEEECCCCCCCHHHEEEECCCCCCCCCEEECCCCCEEEEECC
SIKVKGGKTIPYNVTITRHGPVISEFADKGKEKTKTVFSLKWTALEPSAELKAVLNMNKA
CEEECCCCCCEEEEEEEECCCHHHHHHHCCHHHHCEEEEEEEEEECCCHHHHHHHCCCCC
KDWNEFETALQDFHTPTQNFVFASNDGTIAYKANGNIPVRKKGDGSLPVPGWTDEYEWEG
CCHHHHHHHHHHHCCCCCCEEEECCCCEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCC
YIPFDQLPKVINPKQGFISTANNKIVDDDYPYHISNTWAQPYRQMRIQEFLQEKEKYTVK
CCCHHHCCHHCCCCCCCEECCCCCEECCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCHH
DLEELQMDQKNLYGKEFTPIFLKELNKASLNEVEKEGVDQLTKWNFYDSKDEAAPLIFHL
HHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
LMKEISNTLFSKEIPKDVLELFEGKSQVVDELIRKEVAGENSVWFTKYGGFTKVVHTSYE
HHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHH
NVMKKLQKEYGPDVGEWKWGDYHQLAFTHPISKSSSMLALLAFNREKPVPIGGSQVTVQA
HHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCEEEEEE
ASYGENGIVNHGASWRFIIDTKDMSNGYHIVGPGQSGHFRSDWYHDQIDDWVNGTYHTTT
ECCCCCCCEECCCCEEEEEECCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHCCCEEEEE
LNTEGIEGKVLTLQPK
ECCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3680178 [H]