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The map label for this gene is 218235704

Identifier: 218235704

GI number: 218235704

Start: 1768166

End: 1769089

Strand: Direct

Name: 218235704

Synonym: BCB4264_A1861

Alternate gene names: NA

Gene position: 1768166-1769089 (Clockwise)

Preceding gene: 218232069

Following gene: 218233614

Centisome position: 32.63

GC content: 35.28

Gene sequence:

>924_bases
ATGAATGTACAGGAAAGTTTCGTTACGGCATTGGATGGATCGGAAATTTATTTGCGTAAGTGGTTACCAGAAGGAGATCC
GAGAGGAATTATTCAAATTGCACATGGCATGACAGAGCATGCAGGGGTGTATACAGAATTTGTAGATGCTTTATTGGAAG
CAGGGTATGGTGTTTATGCGCATGATCATAAAGGACATGGGAAAACAGTAAAAAAAGAAGAAGATTATGGTCATTTTGAA
CCAAATATAGGGTGGAATCAAGTTGTATCGGATGTTATCTTTGTTTCAGAAAGGATAAAAGAAGAGCAGTCAAGTCCTTT
GTTTTTACTTGGACATAGTATGGGTTCTTTTTTATCAAGACGTGCTGTACAACTTAGGGGTGAACTATACGATGGATTTC
TGATTTCAGGAACAGGTGGAAATCCAGGGCTTTTAGGAGCTATTGGTCATAAAGTAGCAACAATCGAAATGAAATTGCGC
GGGGCAAAAACGAAAAGTCCAATGTTAAACTTTTTATCTTTCGGAAACTTCAATTCGAACTTTAAGCCAAATCGTACAAA
ATTTGATTGGTTATCTTCAGATAATAATCAAGTTGATAAATATATTGCGGATCCGTTATGTGGTTTCATTTGTACGACGA
GTTTTTACCGAGAATTATTTTCTGGAGTATTAGAAGTAAATAAACTAGAAGAATACAAGAAGACGCCAAAGAATCTTCCA
ATACATATATTCTCTGGTGATCGTGATCCTGTTGGCGATATGGGGAAAGGTGTAAAAGAAGTATATGAAAACTATAAAAA
ATGTGGTGTGAAAGATGTGACACTACGTTTATATGAAAATGGTAGACATGAAATGTTTCATGAAGTAAATAAGGATGAAG
TATTTAAAGATTTAATTTCGTGGTTAGATGCGCATAATAAATGA

Upstream 100 bases:

>100_bases
TTTGTCATAATGAAAGCAATTACATATAATATAAAATAAGAAAAGTGAATGGATATTCATTTTCTTAAAGCTATACATAA
TAGAGTTGGGGGCTGACGAA

Downstream 100 bases:

>100_bases
GAAAGATAATCCCAAACTGTTTGTAGTTTGGGATTATCTATTATACAGAAATAGGGGCAATAAATTCTTAAATTCACTTT
ACTTAATAAAAAATAAAGAA

Product: hydrolase, alpha/beta fold family

Products: glycerophosphocholine; carboxylate

Alternate protein names: Alpha/Beta Hydrolase Fold Protein; Alpha/Beta Hydrolase Fold; Alpha/Beta Fold Family Hydrolase; Hydrolase; Hydrolase Alpha/Beta Fold Family; Alpha/Beta Hydrolase; Hydrolase Alpha/Beta Hydrolase Fold Family; Acylglycerol Lipase; Lipase; Lysophospholipase Protein; Lysophospholipase-Like Protein; Carboxylic Ester Hydrolase; Alpha/Beta Hydrolase Fold-Domain Containing Protein; Monoglyceride Lipase; Alpha/Beta Hydrolase Family Protein; S33 Family Lysophospholipase; Alpha/Beta Fold Family Protein Hydrolase; Aminopeptidase; Hydrolase Alpha/Beta Domain-Containing Protein; Lysophospholipase/Monoglyceride Lipase; Alpha/Beta Hydrolase Superfamily Lysophospholipase

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MNVQESFVTALDGSEIYLRKWLPEGDPRGIIQIAHGMTEHAGVYTEFVDALLEAGYGVYAHDHKGHGKTVKKEEDYGHFE
PNIGWNQVVSDVIFVSERIKEEQSSPLFLLGHSMGSFLSRRAVQLRGELYDGFLISGTGGNPGLLGAIGHKVATIEMKLR
GAKTKSPMLNFLSFGNFNSNFKPNRTKFDWLSSDNNQVDKYIADPLCGFICTTSFYRELFSGVLEVNKLEEYKKTPKNLP
IHIFSGDRDPVGDMGKGVKEVYENYKKCGVKDVTLRLYENGRHEMFHEVNKDEVFKDLISWLDAHNK

Sequences:

>Translated_307_residues
MNVQESFVTALDGSEIYLRKWLPEGDPRGIIQIAHGMTEHAGVYTEFVDALLEAGYGVYAHDHKGHGKTVKKEEDYGHFE
PNIGWNQVVSDVIFVSERIKEEQSSPLFLLGHSMGSFLSRRAVQLRGELYDGFLISGTGGNPGLLGAIGHKVATIEMKLR
GAKTKSPMLNFLSFGNFNSNFKPNRTKFDWLSSDNNQVDKYIADPLCGFICTTSFYRELFSGVLEVNKLEEYKKTPKNLP
IHIFSGDRDPVGDMGKGVKEVYENYKKCGVKDVTLRLYENGRHEMFHEVNKDEVFKDLISWLDAHNK
>Mature_307_residues
MNVQESFVTALDGSEIYLRKWLPEGDPRGIIQIAHGMTEHAGVYTEFVDALLEAGYGVYAHDHKGHGKTVKKEEDYGHFE
PNIGWNQVVSDVIFVSERIKEEQSSPLFLLGHSMGSFLSRRAVQLRGELYDGFLISGTGGNPGLLGAIGHKVATIEMKLR
GAKTKSPMLNFLSFGNFNSNFKPNRTKFDWLSSDNNQVDKYIADPLCGFICTTSFYRELFSGVLEVNKLEEYKKTPKNLP
IHIFSGDRDPVGDMGKGVKEVYENYKKCGVKDVTLRLYENGRHEMFHEVNKDEVFKDLISWLDAHNK

Specific function: Unknown

COG id: COG2267

COG function: function code I; Lysophospholipase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI51242953, Length=305, Percent_Identity=28.5245901639344, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI6005786, Length=305, Percent_Identity=28.5245901639344, Blast_Score=95, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.1.5

Molecular weight: Translated: 34693; Mature: 34693

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS00120 LIPASE_SER ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVQESFVTALDGSEIYLRKWLPEGDPRGIIQIAHGMTEHAGVYTEFVDALLEAGYGVYA
CCCHHHHHHHCCCCCEEHEECCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEE
HDHKGHGKTVKKEEDYGHFEPNIGWNQVVSDVIFVSERIKEEQSSPLFLLGHSMGSFLSR
ECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHH
RAVQLRGELYDGFLISGTGGNPGLLGAIGHKVATIEMKLRGAKTKSPMLNFLSFGNFNSN
HHHHHHHHHCCCEEEECCCCCCCHHHHHCCEEEEEEEEECCCCCCHHHHHHHHHCCCCCC
FKPNRTKFDWLSSDNNQVDKYIADPLCGFICTTSFYRELFSGVLEVNKLEEYKKTPKNLP
CCCCCCEECEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
IHIFSGDRDPVGDMGKGVKEVYENYKKCGVKDVTLRLYENGRHEMFHEVNKDEVFKDLIS
EEEECCCCCCCCHHHHHHHHHHHHHHHCCCHHEEHEEHHCCHHHHHHHCCHHHHHHHHHH
WLDAHNK
HHHCCCC
>Mature Secondary Structure
MNVQESFVTALDGSEIYLRKWLPEGDPRGIIQIAHGMTEHAGVYTEFVDALLEAGYGVYA
CCCHHHHHHHCCCCCEEHEECCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEE
HDHKGHGKTVKKEEDYGHFEPNIGWNQVVSDVIFVSERIKEEQSSPLFLLGHSMGSFLSR
ECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHH
RAVQLRGELYDGFLISGTGGNPGLLGAIGHKVATIEMKLRGAKTKSPMLNFLSFGNFNSN
HHHHHHHHHCCCEEEECCCCCCCHHHHHCCEEEEEEEEECCCCCCHHHHHHHHHCCCCCC
FKPNRTKFDWLSSDNNQVDKYIADPLCGFICTTSFYRELFSGVLEVNKLEEYKKTPKNLP
CCCCCCEECEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
IHIFSGDRDPVGDMGKGVKEVYENYKKCGVKDVTLRLYENGRHEMFHEVNKDEVFKDLIS
EEEECCCCCCCCHHHHHHHHHHHHHHHCCCHHEEHEEHHCCHHHHHHHCCHHHHHHHHHH
WLDAHNK
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-lysophosphatidylcholine; H2O

Specific reaction: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA