Click here to switch to the map view.

The map label for this gene is xerC [H]

Identifier: 218235700

GI number: 218235700

Start: 3850699

End: 3851598

Strand: Reverse

Name: xerC [H]

Synonym: BCB4264_A3929

Alternate gene names: 218235700

Gene position: 3851598-3850699 (Counterclockwise)

Preceding gene: 218231463

Following gene: 218233809

Centisome position: 71.08

GC content: 36.89

Gene sequence:

>900_bases
GTGAATGTGAAGAAATTGTTACAATTATTCGTTGGATATTTACAAATTGAAAGAAATTATTCAAAATATACAATTGCAAG
TTATCAAAATGATTTAGAACATTTTGTGCAATTTATGGAACGAGAAGGCATATCCTCTTTTTTAGACGTTACATACGCGG
ATGTTCGTTTGTACTTAACGACGTTGCACGATGAAAAGTTAGCCCGTAAATCTGTCGCAAGAAAAGTATCAAGCTTACGA
AGTTTATATCGTTTTTTGATGCGTGAAGGTTATCGAAAGGATAATCCGTTTGCACTTGCGTCACTCCCCAAAAAAGAATT
GTCAATCCCAAAGTTTTTATATGCTGAAGAGTTAGAGGAATTATTTGAAGTTTCTGACACGGAAACGCCATTAGGCCAAA
GGAATCAAGCTTTATTAGAGTTGATGTATGCGACTGGGATCCGTGTGAGTGAATGTGTCAATTTACAACTTACCGATATT
GACTTTGCGGTGGGAACAATTTTAGTAATGGGAAAAGGAAAAAAACAAAGGTATATCCCGTTCGGAAGCTATGCGCAAGA
TTCTTTAATTACTTATATAGAGAATGGGAGAAAACAGTTAGTTAATAAGACTGACGAAGATTCTCATATGGTATTTTTAA
ATGCGAAAGGTACACCGCTAACAAGTCGTGGGGTTCGTTATGTTTTAAATGAACTCATTAAAAAGGCTTCGCTGACAATG
CGGATAAGTCCCCATATGTTAAGGCATACATTTGCTACACATATGCTAGATGAAGGGGCGGATTTACGTACTGTACAGGA
GCTATTAGGCCATGAAAATTTGTCGACGACACAAATTTATACGCATGTCTCTAAAGAAAGATTGCGTTCTGTTTACATGA
AGCATCACCCGCGGGCATAA

Upstream 100 bases:

>100_bases
CTTTAGAAACGATTCGAAATTTTGTAAATATTTAGTTAAATTTCTTGCAAAGGCTACTAAGTTGTGATACGATTTAGTAG
CCTTTATTGAGGTGAGTTGT

Downstream 100 bases:

>100_bases
ATTGCTTTAAAAGCTATAAAAACAAATAAAGGAGTTTTTTCTATGGGAAATTTCCACGCTACAACGATATTTGCAGTTCA
TCATAATGGAGAATGTGCAA

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MNVKKLLQLFVGYLQIERNYSKYTIASYQNDLEHFVQFMEREGISSFLDVTYADVRLYLTTLHDEKLARKSVARKVSSLR
SLYRFLMREGYRKDNPFALASLPKKELSIPKFLYAEELEELFEVSDTETPLGQRNQALLELMYATGIRVSECVNLQLTDI
DFAVGTILVMGKGKKQRYIPFGSYAQDSLITYIENGRKQLVNKTDEDSHMVFLNAKGTPLTSRGVRYVLNELIKKASLTM
RISPHMLRHTFATHMLDEGADLRTVQELLGHENLSTTQIYTHVSKERLRSVYMKHHPRA

Sequences:

>Translated_299_residues
MNVKKLLQLFVGYLQIERNYSKYTIASYQNDLEHFVQFMEREGISSFLDVTYADVRLYLTTLHDEKLARKSVARKVSSLR
SLYRFLMREGYRKDNPFALASLPKKELSIPKFLYAEELEELFEVSDTETPLGQRNQALLELMYATGIRVSECVNLQLTDI
DFAVGTILVMGKGKKQRYIPFGSYAQDSLITYIENGRKQLVNKTDEDSHMVFLNAKGTPLTSRGVRYVLNELIKKASLTM
RISPHMLRHTFATHMLDEGADLRTVQELLGHENLSTTQIYTHVSKERLRSVYMKHHPRA
>Mature_299_residues
MNVKKLLQLFVGYLQIERNYSKYTIASYQNDLEHFVQFMEREGISSFLDVTYADVRLYLTTLHDEKLARKSVARKVSSLR
SLYRFLMREGYRKDNPFALASLPKKELSIPKFLYAEELEELFEVSDTETPLGQRNQALLELMYATGIRVSECVNLQLTDI
DFAVGTILVMGKGKKQRYIPFGSYAQDSLITYIENGRKQLVNKTDEDSHMVFLNAKGTPLTSRGVRYVLNELIKKASLTM
RISPHMLRHTFATHMLDEGADLRTVQELLGHENLSTTQIYTHVSKERLRSVYMKHHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=291, Percent_Identity=38.8316151202749, Blast_Score=210, Evalue=7e-56,
Organism=Escherichia coli, GI1790244, Length=292, Percent_Identity=37.6712328767123, Blast_Score=198, Evalue=4e-52,
Organism=Escherichia coli, GI1790767, Length=183, Percent_Identity=28.9617486338798, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790768, Length=192, Percent_Identity=23.4375, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34599; Mature: 34599

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVKKLLQLFVGYLQIERNYSKYTIASYQNDLEHFVQFMEREGISSFLDVTYADVRLYLT
CCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
TLHDEKLARKSVARKVSSLRSLYRFLMREGYRKDNPFALASLPKKELSIPKFLYAEELEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHCCCCHHHHHHHHHH
LFEVSDTETPLGQRNQALLELMYATGIRVSECVNLQLTDIDFAVGTILVMGKGKKQRYIP
HHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCCEEECHHHHHHHEEEECCCCCCCCCC
FGSYAQDSLITYIENGRKQLVNKTDEDSHMVFLNAKGTPLTSRGVRYVLNELIKKASLTM
CCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHEE
RISPHMLRHTFATHMLDEGADLRTVQELLGHENLSTTQIYTHVSKERLRSVYMKHHPRA
EECHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNVKKLLQLFVGYLQIERNYSKYTIASYQNDLEHFVQFMEREGISSFLDVTYADVRLYLT
CCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
TLHDEKLARKSVARKVSSLRSLYRFLMREGYRKDNPFALASLPKKELSIPKFLYAEELEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHCCCCHHHHHHHHHH
LFEVSDTETPLGQRNQALLELMYATGIRVSECVNLQLTDIDFAVGTILVMGKGKKQRYIP
HHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCCEEECHHHHHHHEEEECCCCCCCCCC
FGSYAQDSLITYIENGRKQLVNKTDEDSHMVFLNAKGTPLTSRGVRYVLNELIKKASLTM
CCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHEE
RISPHMLRHTFATHMLDEGADLRTVQELLGHENLSTTQIYTHVSKERLRSVYMKHHPRA
EECHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA