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The map label for this gene is trpS [H]

Identifier: 218235571

GI number: 218235571

Start: 1198127

End: 1199116

Strand: Reverse

Name: trpS [H]

Synonym: BCB4264_A1232

Alternate gene names: 218235571

Gene position: 1199116-1198127 (Counterclockwise)

Preceding gene: 218234912

Following gene: 218231225

Centisome position: 22.13

GC content: 38.99

Gene sequence:

>990_bases
ATGTCAGTTATCTTTTCTGGTATTCAACCAAGTGGAACGATTACACTTGGAAACTATTTAGGAGCAATGAAGCAGTTTAC
AGAGCTTCAAAATGAACACGACTGTTATTTCTGTATTGTAAACCAACATGCGATTACAGTACCTCAAGATCCCGTCGGGC
TTCGTAAAAACATCCGCAGTCTTGCTGCACTTTATGTAGCATGCGGCATCGATCCTGAAAAAGCTACTTTATTTGTACAA
TCAGAAGTACCAGCACACGCTCAACTAGGATGGATCATGCAATCTGTTGCTTACGTTGGAGAATTAGAACGTATGACGCA
ATATAAAGATAAAGCTTCTGGTAGAGATTCAGTTCCAGCTGGATTACTTACGTATCCACCATTAATGGCTGCTGATATTT
TACTTTACAACACTGAAATCGTACCGGTTGGTGATGACCAAAAGCAACATATCGAATTAACACGTGATTTAGCAGAGCGT
TTCAACAAACGTTACCGCGAAATCTTCACAATGCCTGAAATTCGCATTCCAAAAGTAGGAGCTCGCGTTATGTCATTAAC
AGAGCCTACGAAAAAAATGAGTAAATCTGATCCGAATCCAAAATCAATGATTAGTATGCTTGATGAGCCAAAAACAATTG
AAAAGAAAATTAAGAGTGCTGTAACTGACTCTGAAGGTATTGTGAAATTTGATAAGGAAAACAAACCTGGTATCTCTAAT
TTATTAACAATCTACTCTTCATTCTCTGGAAAAACAGTTGAAGAAATCGAAGCAATGTACGAAGGAAAAGGATACGGCGA
CTTCAAAGGCGACCTAGCGCAAGTAGTCGTAGAAGCAATTCGTCCAATCCAAGACAAATATAACGAACTAATCAACTCAC
CAGAACTAGACGAAATCCTAGACAAAGGTGCAGAAAAAGCAAACCGCGTTGCATTCAAACAACTACGCAAAGTAGAAAAC
GCAATGGGACTAAGCAGAAAACGTAGGTAA

Upstream 100 bases:

>100_bases
ACCACGGTCCATTCGTCCCTATAGTTTTTTGGGATGAATGGGCTTTTTTGTTTGCCTTCTCTTCCCCACATCACGCATTC
TATTTTAGGAGGAATTACTT

Downstream 100 bases:

>100_bases
CATATAAAGCGGAGGCGACTGCTTAGCCCTGACGGCTAAGGTTCTTTCCCACAGAAGGTGCTTTTTACCTTCTTATGGGG
AAGGTTCTTAGACGCGAAGG

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MSVIFSGIQPSGTITLGNYLGAMKQFTELQNEHDCYFCIVNQHAITVPQDPVGLRKNIRSLAALYVACGIDPEKATLFVQ
SEVPAHAQLGWIMQSVAYVGELERMTQYKDKASGRDSVPAGLLTYPPLMAADILLYNTEIVPVGDDQKQHIELTRDLAER
FNKRYREIFTMPEIRIPKVGARVMSLTEPTKKMSKSDPNPKSMISMLDEPKTIEKKIKSAVTDSEGIVKFDKENKPGISN
LLTIYSSFSGKTVEEIEAMYEGKGYGDFKGDLAQVVVEAIRPIQDKYNELINSPELDEILDKGAEKANRVAFKQLRKVEN
AMGLSRKRR

Sequences:

>Translated_329_residues
MSVIFSGIQPSGTITLGNYLGAMKQFTELQNEHDCYFCIVNQHAITVPQDPVGLRKNIRSLAALYVACGIDPEKATLFVQ
SEVPAHAQLGWIMQSVAYVGELERMTQYKDKASGRDSVPAGLLTYPPLMAADILLYNTEIVPVGDDQKQHIELTRDLAER
FNKRYREIFTMPEIRIPKVGARVMSLTEPTKKMSKSDPNPKSMISMLDEPKTIEKKIKSAVTDSEGIVKFDKENKPGISN
LLTIYSSFSGKTVEEIEAMYEGKGYGDFKGDLAQVVVEAIRPIQDKYNELINSPELDEILDKGAEKANRVAFKQLRKVEN
AMGLSRKRR
>Mature_328_residues
SVIFSGIQPSGTITLGNYLGAMKQFTELQNEHDCYFCIVNQHAITVPQDPVGLRKNIRSLAALYVACGIDPEKATLFVQS
EVPAHAQLGWIMQSVAYVGELERMTQYKDKASGRDSVPAGLLTYPPLMAADILLYNTEIVPVGDDQKQHIELTRDLAERF
NKRYREIFTMPEIRIPKVGARVMSLTEPTKKMSKSDPNPKSMISMLDEPKTIEKKIKSAVTDSEGIVKFDKENKPGISNL
LTIYSSFSGKTVEEIEAMYEGKGYGDFKGDLAQVVVEAIRPIQDKYNELINSPELDEILDKGAEKANRVAFKQLRKVENA
MGLSRKRR

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=324, Percent_Identity=41.0493827160494, Blast_Score=261, Evalue=9e-70,
Organism=Homo sapiens, GI41352700, Length=172, Percent_Identity=51.1627906976744, Blast_Score=185, Evalue=4e-47,
Organism=Escherichia coli, GI1789786, Length=329, Percent_Identity=53.4954407294833, Blast_Score=363, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI71982800, Length=331, Percent_Identity=40.785498489426, Blast_Score=248, Evalue=3e-66,
Organism=Caenorhabditis elegans, GI71982793, Length=331, Percent_Identity=40.785498489426, Blast_Score=247, Evalue=6e-66,
Organism=Saccharomyces cerevisiae, GI6320474, Length=345, Percent_Identity=40.5797101449275, Blast_Score=248, Evalue=9e-67,
Organism=Drosophila melanogaster, GI24666151, Length=324, Percent_Identity=42.2839506172839, Blast_Score=266, Evalue=2e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 36840; Mature: 36709

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVIFSGIQPSGTITLGNYLGAMKQFTELQNEHDCYFCIVNQHAITVPQDPVGLRKNIRS
CCEEECCCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEEEECCCEEECCCCCHHHHHHHHH
LAALYVACGIDPEKATLFVQSEVPAHAQLGWIMQSVAYVGELERMTQYKDKASGRDSVPA
HHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GLLTYPPLMAADILLYNTEIVPVGDDQKQHIELTRDLAERFNKRYREIFTMPEIRIPKVG
CHHHCCHHHHHHHHEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
ARVMSLTEPTKKMSKSDPNPKSMISMLDEPKTIEKKIKSAVTDSEGIVKFDKENKPGISN
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEECCCCCCCHHH
LLTIYSSFSGKTVEEIEAMYEGKGYGDFKGDLAQVVVEAIRPIQDKYNELINSPELDEIL
HHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
DKGAEKANRVAFKQLRKVENAMGLSRKRR
HHHHHHHHHHHHHHHHHHHHHHCCHHCCC
>Mature Secondary Structure 
SVIFSGIQPSGTITLGNYLGAMKQFTELQNEHDCYFCIVNQHAITVPQDPVGLRKNIRS
CEEECCCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEEEECCCEEECCCCCHHHHHHHHH
LAALYVACGIDPEKATLFVQSEVPAHAQLGWIMQSVAYVGELERMTQYKDKASGRDSVPA
HHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GLLTYPPLMAADILLYNTEIVPVGDDQKQHIELTRDLAERFNKRYREIFTMPEIRIPKVG
CHHHCCHHHHHHHHEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
ARVMSLTEPTKKMSKSDPNPKSMISMLDEPKTIEKKIKSAVTDSEGIVKFDKENKPGISN
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEECCCCCCCHHH
LLTIYSSFSGKTVEEIEAMYEGKGYGDFKGDLAQVVVEAIRPIQDKYNELINSPELDEIL
HHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
DKGAEKANRVAFKQLRKVENAMGLSRKRR
HHHHHHHHHHHHHHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]