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The map label for this gene is serC [H]

Identifier: 218235516

GI number: 218235516

Start: 3151138

End: 3152220

Strand: Reverse

Name: serC [H]

Synonym: BCB4264_A3261

Alternate gene names: 218235516

Gene position: 3152220-3151138 (Counterclockwise)

Preceding gene: 218230959

Following gene: 218235354

Centisome position: 58.17

GC content: 37.3

Gene sequence:

>1083_bases
ATGGAGAGAGTCTATAATTTTTCAGCAGGACCATCAATACTCCCTTTGCCAGTTTTAGAGAAAGTGCAAAAGGAGCTTGT
AAATTATAACGGGACAGGCATGTCAATTATGGAAATGAGTCATCGATCTTCTTATTTTCAAAGTATTATAGAGGAAGCGA
GTAACTTACTTCGTGAATTAATGAGCATCCCTGATGAGTATGAAGTTTTATTTTTACAAGGCGGTGCGTCATTACAATTC
TCTATGATACCGTTGAACTTAATGAATACGTATAAAAAAGCTGGATACGTACTAACTGGCTCATGGTCTAAAAAGGCATT
GCAAGAAGCCGAAAAAGTTGGGGAAGTACAAGTGATTGCTTCTTCCGAGCAAGAGAAGTTTACTACGATTCCTAAACTGG
ACGGTTTATTAAGTGATGAAAAACTAGATTATGTACATATTACAACGAATAATACAATTGAGGGGACAAAATATGTGGAC
ATTCCACATGTAGAAAAAGTGCCGCTCGTTGCGGATATGTCCTCAAATATTTTATCAGAGCGATATGATGTTTCGAAGTT
TGGTCTTATATATGCGGGGGCGCAAAAGAATTTAGGACCTGCGGGCTTAACGATTGCTATTATAAAAAGAGATTTAATTG
GGGGAGCAGATCGCTCTTGTCCGACAATGTTAAATTATGAAACTTACAGTAAAAATAACTCCTTATATAATACACCGCCG
TCCTTTAGTATTTACGTAACGAAACTTGTACTAGAGTGGTTGAAAGAGCAAGGCGGAGTATCTGCGATTGAAGAACAAAA
TAGAATGAAATCTTCACTTCTTTATAATTTCTTAGATGAATCAAAATTGTTTACTTCACCAGTTGATCCTACGTATCGAT
CACTTATGAACATTCCGTTTACAACACCGTCAGAAGAGCTGAACAGTGAGTTTTTACAAAAAGCGAAAGAACGAGGACTT
GTTACGTTAAAAGGGCATCGATCAGTCGGTGGTATGCGCGCTAGTATTTACAATGCGATGCCAGTACAAGGCGTACAGCA
ATTAGTAAATTATATGAAGGAATTTGAGCTTGAGAATAGATAG

Upstream 100 bases:

>100_bases
CTAATAATAGAAAACAAATTGACCGTATATTATATTTTGGGTTATAATTCAGAAAGTTTAAAAATTAATAAAAATGAGAA
ATAGGGAGGTTATGAGGGTA

Downstream 100 bases:

>100_bases
GGAGATGGGGATATGTTTCGTGTTCAAACGTTAAATCAAATTGCAGAAAAAGGTTTGCAAGTTTTTACTGAAGAACGTTA
TGAAGTAGGAGATAGAATCA

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MERVYNFSAGPSILPLPVLEKVQKELVNYNGTGMSIMEMSHRSSYFQSIIEEASNLLRELMSIPDEYEVLFLQGGASLQF
SMIPLNLMNTYKKAGYVLTGSWSKKALQEAEKVGEVQVIASSEQEKFTTIPKLDGLLSDEKLDYVHITTNNTIEGTKYVD
IPHVEKVPLVADMSSNILSERYDVSKFGLIYAGAQKNLGPAGLTIAIIKRDLIGGADRSCPTMLNYETYSKNNSLYNTPP
SFSIYVTKLVLEWLKEQGGVSAIEEQNRMKSSLLYNFLDESKLFTSPVDPTYRSLMNIPFTTPSEELNSEFLQKAKERGL
VTLKGHRSVGGMRASIYNAMPVQGVQQLVNYMKEFELENR

Sequences:

>Translated_360_residues
MERVYNFSAGPSILPLPVLEKVQKELVNYNGTGMSIMEMSHRSSYFQSIIEEASNLLRELMSIPDEYEVLFLQGGASLQF
SMIPLNLMNTYKKAGYVLTGSWSKKALQEAEKVGEVQVIASSEQEKFTTIPKLDGLLSDEKLDYVHITTNNTIEGTKYVD
IPHVEKVPLVADMSSNILSERYDVSKFGLIYAGAQKNLGPAGLTIAIIKRDLIGGADRSCPTMLNYETYSKNNSLYNTPP
SFSIYVTKLVLEWLKEQGGVSAIEEQNRMKSSLLYNFLDESKLFTSPVDPTYRSLMNIPFTTPSEELNSEFLQKAKERGL
VTLKGHRSVGGMRASIYNAMPVQGVQQLVNYMKEFELENR
>Mature_360_residues
MERVYNFSAGPSILPLPVLEKVQKELVNYNGTGMSIMEMSHRSSYFQSIIEEASNLLRELMSIPDEYEVLFLQGGASLQF
SMIPLNLMNTYKKAGYVLTGSWSKKALQEAEKVGEVQVIASSEQEKFTTIPKLDGLLSDEKLDYVHITTNNTIEGTKYVD
IPHVEKVPLVADMSSNILSERYDVSKFGLIYAGAQKNLGPAGLTIAIIKRDLIGGADRSCPTMLNYETYSKNNSLYNTPP
SFSIYVTKLVLEWLKEQGGVSAIEEQNRMKSSLLYNFLDESKLFTSPVDPTYRSLMNIPFTTPSEELNSEFLQKAKERGL
VTLKGHRSVGGMRASIYNAMPVQGVQQLVNYMKEFELENR

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=361, Percent_Identity=47.9224376731302, Blast_Score=348, Evalue=4e-96,
Organism=Homo sapiens, GI10863955, Length=356, Percent_Identity=42.9775280898876, Blast_Score=296, Evalue=2e-80,
Organism=Escherichia coli, GI1787136, Length=359, Percent_Identity=44.0111420612813, Blast_Score=322, Evalue=3e-89,
Organism=Caenorhabditis elegans, GI17506897, Length=360, Percent_Identity=44.4444444444444, Blast_Score=328, Evalue=4e-90,
Organism=Saccharomyces cerevisiae, GI6324758, Length=391, Percent_Identity=41.1764705882353, Blast_Score=289, Evalue=4e-79,
Organism=Drosophila melanogaster, GI21356589, Length=363, Percent_Identity=47.9338842975207, Blast_Score=342, Evalue=3e-94,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 40414; Mature: 40414

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERVYNFSAGPSILPLPVLEKVQKELVNYNGTGMSIMEMSHRSSYFQSIIEEASNLLREL
CCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MSIPDEYEVLFLQGGASLQFSMIPLNLMNTYKKAGYVLTGSWSKKALQEAEKVGEVQVIA
HCCCCCEEEEEEECCCCEEEEEECHHHHHHHHHCCEEEECCCHHHHHHHHHHCCCEEEEE
SSEQEKFTTIPKLDGLLSDEKLDYVHITTNNTIEGTKYVDIPHVEKVPLVADMSSNILSE
CCCCHHHCCCCHHCCCCCCCCCCEEEEEECCEECCCEEECCCCCCCCCCHHHHHHHHHHH
RYDVSKFGLIYAGAQKNLGPAGLTIAIIKRDLIGGADRSCPTMLNYETYSKNNSLYNTPP
HCCHHHCCEEEECCCCCCCCCCEEEEEEHHHHCCCCCCCCCCEECEEEECCCCCCCCCCC
SFSIYVTKLVLEWLKEQGGVSAIEEQNRMKSSLLYNFLDESKLFTSPVDPTYRSLMNIPF
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCC
TTPSEELNSEFLQKAKERGLVTLKGHRSVGGMRASIYNAMPVQGVQQLVNYMKEFELENR
CCCHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MERVYNFSAGPSILPLPVLEKVQKELVNYNGTGMSIMEMSHRSSYFQSIIEEASNLLREL
CCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MSIPDEYEVLFLQGGASLQFSMIPLNLMNTYKKAGYVLTGSWSKKALQEAEKVGEVQVIA
HCCCCCEEEEEEECCCCEEEEEECHHHHHHHHHCCEEEECCCHHHHHHHHHHCCCEEEEE
SSEQEKFTTIPKLDGLLSDEKLDYVHITTNNTIEGTKYVDIPHVEKVPLVADMSSNILSE
CCCCHHHCCCCHHCCCCCCCCCCEEEEEECCEECCCEEECCCCCCCCCCHHHHHHHHHHH
RYDVSKFGLIYAGAQKNLGPAGLTIAIIKRDLIGGADRSCPTMLNYETYSKNNSLYNTPP
HCCHHHCCEEEECCCCCCCCCCEEEEEEHHHHCCCCCCCCCCEECEEEECCCCCCCCCCC
SFSIYVTKLVLEWLKEQGGVSAIEEQNRMKSSLLYNFLDESKLFTSPVDPTYRSLMNIPF
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCC
TTPSEELNSEFLQKAKERGLVTLKGHRSVGGMRASIYNAMPVQGVQQLVNYMKEFELENR
CCCHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA