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The map label for this gene is acoR [H]

Identifier: 218235432

GI number: 218235432

Start: 2673416

End: 2675266

Strand: Reverse

Name: acoR [H]

Synonym: BCB4264_A2772

Alternate gene names: 218235432

Gene position: 2675266-2673416 (Counterclockwise)

Preceding gene: 218236014

Following gene: 218232478

Centisome position: 49.37

GC content: 35.49

Gene sequence:

>1851_bases
ATGTTAGCTTCACCGTTTTACTTACATACATGGAAAAAGTTTGTTAATGAAGGTGTTCTTGATTCAAATCGCATAAATCA
AAGAATTTCAGAATCGTGGCATCGATGTAAACAGGCTAATGTTAATCCTCATATGAATAAAGGTCAGAAAGTTTTGTCTT
CTAATATTTTTCGAGAACAAAAGAAAAAGAGTGAAATTTTCCTTGATATAGCATTACCCCAAATACAAAATATGAGAAAA
ACCATTGATGAACTACAAATGATGGCATTATTAATCGATCCAGATGGTTATGTCCTATCCTTAAGTGGAAATAAACAAAC
GTTAAAGCGAGCGAAACATATTAATTTTATTGAAGGTGTAAAATGGACGGAAGCAGCTGTGGGGACAAACGCAATAGGAA
CAGCGCTAGAAATTGAAGAAGCTATTATGATAAGTGGTACTGAACATTACTCCGTGGTATCTCATAGCTGGAGTTGTGCG
GCTGCTCCCATTCATAACGATGACGGGAAATTAATTGGTATTCTAGATTTCTCCTGTCCAATTGAATTTTCGCATCCATA
TATGCTCGGTATGGTAACTTCAATTGCACATGCGATTGAACGTGAATGTAGCATAAGAGTTCATCAAAATGAATTACACT
TAATCCATCGTTTTTTAGATGTCATTGATAGTGATGAACAAGTAGTTATTTGTAATCATCGTGATGTTATCGTTTCTGCG
AGTAAGAGCGTTCGGGAACGAGTAACTAATTGGTCAAGAATGAAACTTGAAGATTTAGTGCACCATGGATTGGAAACTAA
ATTAGAGATACCGGTATATAGTAATGAAAGAATGATCGGGAAATGTATGTATTTAAAGGAAAACAAACAAATGAATACAT
ATTCTGCTTTCACATTTATAAAAGGAATTACTTTTCCAGGAGTTACCGGGACAAGTAAAGCATTTCAACACACACTAGAA
GAAATTAAGCTTGTTTCACCGACTGATGCTAGTGTGTATGTATGTGGTGAGACAGGAGTAGGAAAGGAATATGTCGCGAG
AGCGATTCATGAAAATAGTCCAAGAAAAGACGGACCCTTTATAGCTGTTAACTGCGGTTCTTTGCCTAAAGAATTAATGG
AAAGTGAATTGTTCGGTTATGCTGAAGGTGCGTTTACAGGTGCGCGACGTCAAGGATATAAAGGGAAATTTGAACAAGCG
AATGGAGGAACACTGTTTTTAGATGAAATTGGCGAAGTACCACCAGAGATGCAAGTAGCCTTATTGCGTGTTTTACAAGA
ACGCACAATAACTCCAATAGGAAGTTCAAAAGAGGTACCAGTAAATATTCGTATTATTACTGCCACACATAAAGATTTAC
TAAGGTTAGTAGAAGAAGGGAAATTCCGTCAAGATTTATATTATCGTTTGCACGTTTATCCGTTATATGTTCCATCGTTA
ATAGAAAGAAAAGAGGATATCCCATATTTTATACAACACTTTTGCGAACGGAAGAATTGGAATGTTGTATTTCCAAAGAG
TATATACAATCAATTTTTACAACATACATGGCCCGGAAATATTCGGGAACTAGTAAATGTATTAGAACGTATTTACATTT
TGTCGCAAGGACGGGAAATATGCGAAAAGCAAGTCGCTTTTTTGATACAAACAATGACGGGAAATCAACAACAACTTGAG
TTACAAGTTGAAAATAAAACAGAACATACATTGAATTTTCGCGAAAAAATACAGCGTGATAGCATGATTGAAGCGTTAGA
AAAGACGAACGGAAATGTTTCGTTAGCCGCAAAACTGTTAAATGTTCCTCGAAGTACATTTTATAAACGAATGCAGAAAT
ATAAGCTATAA

Upstream 100 bases:

>100_bases
TTGTGTCGTATTGCTAGTTGTATTGAAAACGCTTTTATTCAGTTTTATAATAAAAGTATGTTTTATAAATCTCCAAAACA
ATTAAAAGGGAGATGATACA

Downstream 100 bases:

>100_bases
AGTAGATTTTTGTAATCTACTTTTTCTTTGTGGGCTCATGTTCTGTCGGAATGTGCGCTTACCGGGGAAATAATAGAATT
GTTAGAAAATAATTCCCGGA

Product: putative acetoin operon transcriptional activator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 616; Mature: 616

Protein sequence:

>616_residues
MLASPFYLHTWKKFVNEGVLDSNRINQRISESWHRCKQANVNPHMNKGQKVLSSNIFREQKKKSEIFLDIALPQIQNMRK
TIDELQMMALLIDPDGYVLSLSGNKQTLKRAKHINFIEGVKWTEAAVGTNAIGTALEIEEAIMISGTEHYSVVSHSWSCA
AAPIHNDDGKLIGILDFSCPIEFSHPYMLGMVTSIAHAIERECSIRVHQNELHLIHRFLDVIDSDEQVVICNHRDVIVSA
SKSVRERVTNWSRMKLEDLVHHGLETKLEIPVYSNERMIGKCMYLKENKQMNTYSAFTFIKGITFPGVTGTSKAFQHTLE
EIKLVSPTDASVYVCGETGVGKEYVARAIHENSPRKDGPFIAVNCGSLPKELMESELFGYAEGAFTGARRQGYKGKFEQA
NGGTLFLDEIGEVPPEMQVALLRVLQERTITPIGSSKEVPVNIRIITATHKDLLRLVEEGKFRQDLYYRLHVYPLYVPSL
IERKEDIPYFIQHFCERKNWNVVFPKSIYNQFLQHTWPGNIRELVNVLERIYILSQGREICEKQVAFLIQTMTGNQQQLE
LQVENKTEHTLNFREKIQRDSMIEALEKTNGNVSLAAKLLNVPRSTFYKRMQKYKL

Sequences:

>Translated_616_residues
MLASPFYLHTWKKFVNEGVLDSNRINQRISESWHRCKQANVNPHMNKGQKVLSSNIFREQKKKSEIFLDIALPQIQNMRK
TIDELQMMALLIDPDGYVLSLSGNKQTLKRAKHINFIEGVKWTEAAVGTNAIGTALEIEEAIMISGTEHYSVVSHSWSCA
AAPIHNDDGKLIGILDFSCPIEFSHPYMLGMVTSIAHAIERECSIRVHQNELHLIHRFLDVIDSDEQVVICNHRDVIVSA
SKSVRERVTNWSRMKLEDLVHHGLETKLEIPVYSNERMIGKCMYLKENKQMNTYSAFTFIKGITFPGVTGTSKAFQHTLE
EIKLVSPTDASVYVCGETGVGKEYVARAIHENSPRKDGPFIAVNCGSLPKELMESELFGYAEGAFTGARRQGYKGKFEQA
NGGTLFLDEIGEVPPEMQVALLRVLQERTITPIGSSKEVPVNIRIITATHKDLLRLVEEGKFRQDLYYRLHVYPLYVPSL
IERKEDIPYFIQHFCERKNWNVVFPKSIYNQFLQHTWPGNIRELVNVLERIYILSQGREICEKQVAFLIQTMTGNQQQLE
LQVENKTEHTLNFREKIQRDSMIEALEKTNGNVSLAAKLLNVPRSTFYKRMQKYKL
>Mature_616_residues
MLASPFYLHTWKKFVNEGVLDSNRINQRISESWHRCKQANVNPHMNKGQKVLSSNIFREQKKKSEIFLDIALPQIQNMRK
TIDELQMMALLIDPDGYVLSLSGNKQTLKRAKHINFIEGVKWTEAAVGTNAIGTALEIEEAIMISGTEHYSVVSHSWSCA
AAPIHNDDGKLIGILDFSCPIEFSHPYMLGMVTSIAHAIERECSIRVHQNELHLIHRFLDVIDSDEQVVICNHRDVIVSA
SKSVRERVTNWSRMKLEDLVHHGLETKLEIPVYSNERMIGKCMYLKENKQMNTYSAFTFIKGITFPGVTGTSKAFQHTLE
EIKLVSPTDASVYVCGETGVGKEYVARAIHENSPRKDGPFIAVNCGSLPKELMESELFGYAEGAFTGARRQGYKGKFEQA
NGGTLFLDEIGEVPPEMQVALLRVLQERTITPIGSSKEVPVNIRIITATHKDLLRLVEEGKFRQDLYYRLHVYPLYVPSL
IERKEDIPYFIQHFCERKNWNVVFPKSIYNQFLQHTWPGNIRELVNVLERIYILSQGREICEKQVAFLIQTMTGNQQQLE
LQVENKTEHTLNFREKIQRDSMIEALEKTNGNVSLAAKLLNVPRSTFYKRMQKYKL

Specific function: Acts as a transcriptional activator of the acoABCL operon encoding the acetoin dehydrogenase complex [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=315, Percent_Identity=43.4920634920635, Blast_Score=269, Evalue=4e-73,
Organism=Escherichia coli, GI1788905, Length=303, Percent_Identity=44.5544554455446, Blast_Score=265, Evalue=6e-72,
Organism=Escherichia coli, GI87082117, Length=313, Percent_Identity=41.85303514377, Blast_Score=262, Evalue=4e-71,
Organism=Escherichia coli, GI1789233, Length=352, Percent_Identity=36.3636363636364, Blast_Score=232, Evalue=6e-62,
Organism=Escherichia coli, GI1788550, Length=319, Percent_Identity=40.7523510971787, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI1789087, Length=346, Percent_Identity=35.8381502890173, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1786524, Length=320, Percent_Identity=38.4375, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI1790299, Length=332, Percent_Identity=35.8433734939759, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI87082152, Length=330, Percent_Identity=36.969696969697, Blast_Score=205, Evalue=8e-54,
Organism=Escherichia coli, GI87081858, Length=645, Percent_Identity=25.1162790697674, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1787583, Length=296, Percent_Identity=35.8108108108108, Blast_Score=182, Evalue=8e-47,
Organism=Escherichia coli, GI87081872, Length=229, Percent_Identity=41.4847161572052, Blast_Score=179, Evalue=5e-46,
Organism=Escherichia coli, GI1789828, Length=266, Percent_Identity=34.9624060150376, Blast_Score=152, Evalue=7e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 70532; Mature: 70532

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLASPFYLHTWKKFVNEGVLDSNRINQRISESWHRCKQANVNPHMNKGQKVLSSNIFREQ
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
KKKSEIFLDIALPQIQNMRKTIDELQMMALLIDPDGYVLSLSGNKQTLKRAKHINFIEGV
HHCCCEEEEEECHHHHHHHHHHHHHHHHHEEECCCCEEEEECCCHHHHHHHHCCCHHHCC
KWTEAAVGTNAIGTALEIEEAIMISGTEHYSVVSHSWSCAAAPIHNDDGKLIGILDFSCP
CHHHHHCCCCCCCCHHEECCEEEEECCCCEEEEECCCCEEECCEECCCCCEEEEEECCCC
IEFSHPYMLGMVTSIAHAIERECSIRVHQNELHLIHRFLDVIDSDEQVVICNHRDVIVSA
CCCCCCHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHCCCCEEEEECCCCEEEEC
SKSVRERVTNWSRMKLEDLVHHGLETKLEIPVYSNERMIGKCMYLKENKQMNTYSAFTFI
HHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEEECCCCCCHHHHHHHH
KGITFPGVTGTSKAFQHTLEEIKLVSPTDASVYVCGETGVGKEYVARAIHENSPRKDGPF
HCCCCCCCCCCHHHHHHHHHHCEECCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCE
IAVNCGSLPKELMESELFGYAEGAFTGARRQGYKGKFEQANGGTLFLDEIGEVPPEMQVA
EEEECCCCHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCCEEEHHHHCCCCHHHHHH
LLRVLQERTITPIGSSKEVPVNIRIITATHKDLLRLVEEGKFRQDLYYRLHVYPLYVPSL
HHHHHHHCCCCCCCCCCCCEEEEEEEEECHHHHHHHHHCCCHHHCEEEEEEEEEEHHHHH
IERKEDIPYFIQHFCERKNWNVVFPKSIYNQFLQHTWPGNIRELVNVLERIYILSQGREI
HHHCCCCHHHHHHHHCCCCCCEEECHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHH
CEKQVAFLIQTMTGNQQQLELQVENKTEHTLNFREKIQRDSMIEALEKTNGNVSLAAKLL
HHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
NVPRSTFYKRMQKYKL
HCCHHHHHHHHHHCCC
>Mature Secondary Structure
MLASPFYLHTWKKFVNEGVLDSNRINQRISESWHRCKQANVNPHMNKGQKVLSSNIFREQ
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
KKKSEIFLDIALPQIQNMRKTIDELQMMALLIDPDGYVLSLSGNKQTLKRAKHINFIEGV
HHCCCEEEEEECHHHHHHHHHHHHHHHHHEEECCCCEEEEECCCHHHHHHHHCCCHHHCC
KWTEAAVGTNAIGTALEIEEAIMISGTEHYSVVSHSWSCAAAPIHNDDGKLIGILDFSCP
CHHHHHCCCCCCCCHHEECCEEEEECCCCEEEEECCCCEEECCEECCCCCEEEEEECCCC
IEFSHPYMLGMVTSIAHAIERECSIRVHQNELHLIHRFLDVIDSDEQVVICNHRDVIVSA
CCCCCCHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHCCCCEEEEECCCCEEEEC
SKSVRERVTNWSRMKLEDLVHHGLETKLEIPVYSNERMIGKCMYLKENKQMNTYSAFTFI
HHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEEECCCCCCHHHHHHHH
KGITFPGVTGTSKAFQHTLEEIKLVSPTDASVYVCGETGVGKEYVARAIHENSPRKDGPF
HCCCCCCCCCCHHHHHHHHHHCEECCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCE
IAVNCGSLPKELMESELFGYAEGAFTGARRQGYKGKFEQANGGTLFLDEIGEVPPEMQVA
EEEECCCCHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCCEEEHHHHCCCCHHHHHH
LLRVLQERTITPIGSSKEVPVNIRIITATHKDLLRLVEEGKFRQDLYYRLHVYPLYVPSL
HHHHHHHCCCCCCCCCCCCEEEEEEEEECHHHHHHHHHCCCHHHCEEEEEEEEEEHHHHH
IERKEDIPYFIQHFCERKNWNVVFPKSIYNQFLQHTWPGNIRELVNVLERIYILSQGREI
HHHCCCCHHHHHHHHCCCCCCEEECHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHH
CEKQVAFLIQTMTGNQQQLELQVENKTEHTLNFREKIQRDSMIEALEKTNGNVSLAAKLL
HHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
NVPRSTFYKRMQKYKL
HCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377; 10368162 [H]