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The map label for this gene is cysS [H]

Identifier: 218235383

GI number: 218235383

Start: 105494

End: 106891

Strand: Direct

Name: cysS [H]

Synonym: BCB4264_A0110

Alternate gene names: 218235383

Gene position: 105494-106891 (Clockwise)

Preceding gene: 218236099

Following gene: 218234559

Centisome position: 1.95

GC content: 36.05

Gene sequence:

>1398_bases
ATGACTATTCACATTTATAATACGTTAACACGTCAAAAAGAAGAGTTTGTTCCATTAGAAGAAAATAAGGTAAAGATGTA
TGTATGCGGACCTACAGTTTATAACTACATTCATATTGGGAATGCAAGGCCTCCTATGGTATTCGATACAGTGCGTCGTT
ATTTAGAATACAAAGGATACGATGTGCAATATGTATCTAACTTTACGGATGTAGATGATAAATTAATTAAAGCGGCAAAT
GAATTAGGTGAAGATGTACCGACAATTGCTGATCGCTTTGTTGAAGCGTACTTTGAAGATGTAACAGCACTAGGTTGCAA
ACACGCAACAGTTCATCCTCGTGTAACAGAAAATATGGATATCATTATTGAATTTATTCAAGAACTTGTGAATAAAGGGT
ATGCATATGAATCAGAGGGTGATGTGTACTTTAAGACGAAGGAATTCGAAGGTTACGGTAAATTATCACATCAACCAATC
GCAGATTTACGTCACGGTGCTCGTATTGAGGTAGGGGAAAAGAAACAAGACCCTCTTGATTTTGCTTTATGGAAAGCTGC
GAAAGAAGGAGAAATCTTCTGGGAAAGCCCTTGGGGGCAAGGACGTCCAGGATGGCATATTGAATGCTCAGCAATGGCGC
GTAAGTACTTAGGGGATACAATTGACATTCATGCTGGTGGTCAAGACTTGGCATTCCCACATCATGAAAATGAAATTGCG
CAGTCAGAAGCATTGACTGGAAAAACGTTTGCACGTTACTGGATGCATAATGGATATATTAATATTAACAATGAGAAGAT
GTCTAAATCGCTGGGTAACTTTATTTTAGTTCACGATATTATTAAGCAATACGACCCGCAGTTAATTAGATTCTTTATGT
TATCAGTACACTATCGTCACCCGATTAACTTTAGTGAAGAGTTATTACAAAGTACGAATAATGGACTGGAAAGAATTAAA
ACAGCTTATGGAAACTTAAAGCATCGTATGGAGAGTAGTACGGATTTAACGGACCATAATGAGAAATGGTTAGCTGAAAT
AGAGAAATTCCAGACTGCATTTGAAGAGGCAATGAATGATGACTTTAACACTGCAAATGCAATTACCGAATTATACAACG
TAGCAAATCATGCAAATCAATATTTACTTGAAGAGCATACATCTAAAGTTGTGATTGAAGCATACGTAAAACAACTGGAA
ACGTTATTTGATATTTTAGGATTAGAATTATCAAAAGAAGAATTACTGGATGAAGAAATTGAAGAGCTTATCCAAAAGCG
CATTGAAGCTCGTAAAAATCGTGATTTTGCATTGTCTGATCAAATTCGTGACGATTTAAAAGAACGTAATATTATTTTAG
AAGATACCGCTCAAGGTACAAGATGGAAAAGAGGATAA

Upstream 100 bases:

>100_bases
GACCTTCCGGATCCGATTTTTGATAAATTAAAGGCTATGGAAGTAGAACTTGATAAATTGAAGAAACAATTGGAATTAAA
GGTAGAAAGGAAGGATAAAA

Downstream 100 bases:

>100_bases
GGATGATCGATGCAAAGCAATTAAACAGCTTGGCGTTAGCGTATATGGGTGATGCGGTATATGAACAATATATCCGCTAT
CACCTCCTTCAAAAAGGAAA

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MTIHIYNTLTRQKEEFVPLEENKVKMYVCGPTVYNYIHIGNARPPMVFDTVRRYLEYKGYDVQYVSNFTDVDDKLIKAAN
ELGEDVPTIADRFVEAYFEDVTALGCKHATVHPRVTENMDIIIEFIQELVNKGYAYESEGDVYFKTKEFEGYGKLSHQPI
ADLRHGARIEVGEKKQDPLDFALWKAAKEGEIFWESPWGQGRPGWHIECSAMARKYLGDTIDIHAGGQDLAFPHHENEIA
QSEALTGKTFARYWMHNGYININNEKMSKSLGNFILVHDIIKQYDPQLIRFFMLSVHYRHPINFSEELLQSTNNGLERIK
TAYGNLKHRMESSTDLTDHNEKWLAEIEKFQTAFEEAMNDDFNTANAITELYNVANHANQYLLEEHTSKVVIEAYVKQLE
TLFDILGLELSKEELLDEEIEELIQKRIEARKNRDFALSDQIRDDLKERNIILEDTAQGTRWKRG

Sequences:

>Translated_465_residues
MTIHIYNTLTRQKEEFVPLEENKVKMYVCGPTVYNYIHIGNARPPMVFDTVRRYLEYKGYDVQYVSNFTDVDDKLIKAAN
ELGEDVPTIADRFVEAYFEDVTALGCKHATVHPRVTENMDIIIEFIQELVNKGYAYESEGDVYFKTKEFEGYGKLSHQPI
ADLRHGARIEVGEKKQDPLDFALWKAAKEGEIFWESPWGQGRPGWHIECSAMARKYLGDTIDIHAGGQDLAFPHHENEIA
QSEALTGKTFARYWMHNGYININNEKMSKSLGNFILVHDIIKQYDPQLIRFFMLSVHYRHPINFSEELLQSTNNGLERIK
TAYGNLKHRMESSTDLTDHNEKWLAEIEKFQTAFEEAMNDDFNTANAITELYNVANHANQYLLEEHTSKVVIEAYVKQLE
TLFDILGLELSKEELLDEEIEELIQKRIEARKNRDFALSDQIRDDLKERNIILEDTAQGTRWKRG
>Mature_464_residues
TIHIYNTLTRQKEEFVPLEENKVKMYVCGPTVYNYIHIGNARPPMVFDTVRRYLEYKGYDVQYVSNFTDVDDKLIKAANE
LGEDVPTIADRFVEAYFEDVTALGCKHATVHPRVTENMDIIIEFIQELVNKGYAYESEGDVYFKTKEFEGYGKLSHQPIA
DLRHGARIEVGEKKQDPLDFALWKAAKEGEIFWESPWGQGRPGWHIECSAMARKYLGDTIDIHAGGQDLAFPHHENEIAQ
SEALTGKTFARYWMHNGYININNEKMSKSLGNFILVHDIIKQYDPQLIRFFMLSVHYRHPINFSEELLQSTNNGLERIKT
AYGNLKHRMESSTDLTDHNEKWLAEIEKFQTAFEEAMNDDFNTANAITELYNVANHANQYLLEEHTSKVVIEAYVKQLET
LFDILGLELSKEELLDEEIEELIQKRIEARKNRDFALSDQIRDDLKERNIILEDTAQGTRWKRG

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=483, Percent_Identity=35.8178053830228, Blast_Score=286, Evalue=3e-77,
Organism=Homo sapiens, GI21269877, Length=346, Percent_Identity=35.2601156069364, Blast_Score=208, Evalue=9e-54,
Organism=Homo sapiens, GI303304987, Length=346, Percent_Identity=35.2601156069364, Blast_Score=208, Evalue=1e-53,
Organism=Homo sapiens, GI10835051, Length=346, Percent_Identity=35.2601156069364, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI62240992, Length=346, Percent_Identity=35.2601156069364, Blast_Score=207, Evalue=1e-53,
Organism=Escherichia coli, GI1786737, Length=473, Percent_Identity=45.0317124735729, Blast_Score=397, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI17509795, Length=353, Percent_Identity=32.0113314447592, Blast_Score=181, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI17509797, Length=353, Percent_Identity=32.0113314447592, Blast_Score=181, Evalue=5e-46,
Organism=Saccharomyces cerevisiae, GI6324082, Length=378, Percent_Identity=35.1851851851852, Blast_Score=204, Evalue=2e-53,
Organism=Drosophila melanogaster, GI19922218, Length=504, Percent_Identity=33.1349206349206, Blast_Score=241, Evalue=1e-63,
Organism=Drosophila melanogaster, GI19922364, Length=323, Percent_Identity=32.8173374613003, Blast_Score=177, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 54036; Mature: 53905

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIHIYNTLTRQKEEFVPLEENKVKMYVCGPTVYNYIHIGNARPPMVFDTVRRYLEYKGY
CEEEEEEHHHHHHHHCCCCCCCCEEEEEECCHHEEEEEECCCCCCHHHHHHHHHHHHCCC
DVQYVSNFTDVDDKLIKAANELGEDVPTIADRFVEAYFEDVTALGCKHATVHPRVTENMD
CEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
IIIEFIQELVNKGYAYESEGDVYFKTKEFEGYGKLSHQPIADLRHGARIEVGEKKQDPLD
HHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHCCCCEEEECCCCCCCHH
FALWKAAKEGEIFWESPWGQGRPGWHIECSAMARKYLGDTIDIHAGGQDLAFPHHENEIA
HHHHHCCCCCCEEEECCCCCCCCCCEEEHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHH
QSEALTGKTFARYWMHNGYININNEKMSKSLGNFILVHDIIKQYDPQLIRFFMLSVHYRH
HHHHHHHHHHHHHHHHCCEEEECHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHCC
PINFSEELLQSTNNGLERIKTAYGNLKHRMESSTDLTDHNEKWLAEIEKFQTAFEEAMND
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
DFNTANAITELYNVANHANQYLLEEHTSKVVIEAYVKQLETLFDILGLELSKEELLDEEI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
EELIQKRIEARKNRDFALSDQIRDDLKERNIILEDTAQGTRWKRG
HHHHHHHHHHHCCCCCCHHHHHHHHHHHCCEEEECCCCCCCCCCC
>Mature Secondary Structure 
TIHIYNTLTRQKEEFVPLEENKVKMYVCGPTVYNYIHIGNARPPMVFDTVRRYLEYKGY
EEEEEEHHHHHHHHCCCCCCCCEEEEEECCHHEEEEEECCCCCCHHHHHHHHHHHHCCC
DVQYVSNFTDVDDKLIKAANELGEDVPTIADRFVEAYFEDVTALGCKHATVHPRVTENMD
CEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
IIIEFIQELVNKGYAYESEGDVYFKTKEFEGYGKLSHQPIADLRHGARIEVGEKKQDPLD
HHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHCCCCEEEECCCCCCCHH
FALWKAAKEGEIFWESPWGQGRPGWHIECSAMARKYLGDTIDIHAGGQDLAFPHHENEIA
HHHHHCCCCCCEEEECCCCCCCCCCEEEHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHH
QSEALTGKTFARYWMHNGYININNEKMSKSLGNFILVHDIIKQYDPQLIRFFMLSVHYRH
HHHHHHHHHHHHHHHHCCEEEECHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHCC
PINFSEELLQSTNNGLERIKTAYGNLKHRMESSTDLTDHNEKWLAEIEKFQTAFEEAMND
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
DFNTANAITELYNVANHANQYLLEEHTSKVVIEAYVKQLETLFDILGLELSKEELLDEEI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
EELIQKRIEARKNRDFALSDQIRDDLKERNIILEDTAQGTRWKRG
HHHHHHHHHHHCCCCCCHHHHHHHHHHHCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA