| Definition | Bacillus cereus B4264, complete genome. |
|---|---|
| Accession | NC_011725 |
| Length | 5,419,036 |
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The map label for this gene is inhA [H]
Identifier: 218235326
GI number: 218235326
Start: 692815
End: 695214
Strand: Direct
Name: inhA [H]
Synonym: BCB4264_A0703
Alternate gene names: 218235326
Gene position: 692815-695214 (Clockwise)
Preceding gene: 218232029
Following gene: 218231855
Centisome position: 12.78
GC content: 37.04
Gene sequence:
>2400_bases ATGAGAAGAAAAGCGCCATTTAAAGTGTTATCGTCATTAGCAATTGCGGCAATTATCGGATGCACATCTGTAATGAGTGC TCCATTAACATACGCAGAAACGCCAGCAAAAGAGAAAGATAATGTATCTACAACACCAATTGATTACAATTTAATTCAAG AAGATCGTTTAGCGGAAGCACTGAAAGAAAGAGGAACAATTAATCCAGCATCTTCTAAAGAAGAGACGAAAAAAGCTGTT GAGCAATATATTGAAAAGAAACAAGGAGATCAGGCGAATAAAGAAATTCTTCCAGATGCTCACTCACAAGAAACGTCTGA TTTCACAAAAAAAGTAAAAGAGAAAAAGATGGAAGAAAAGGAAAATGTAAAAAAGGCTGAAAAAAATGTTAGCCTTGAGC AAAAGCCAGAACCAAATAAAAAGCAATTGAATGGGCAAGTTCCAACTTCAAAAGCAAAGCAAGCTCCATATAAGGGATCT GTTCGATCGGATAAAGTATTAGTGTTACTCGTTGAATTTAGTGATTATAAACATAATAATATTGATCAAACACCAGGTTA TATGTATTCGAAAGACTTTAGTAGAGAACATTATCAAAAGATGTTGTTCGGTAATGAGCCGTATACTTTATTTGATGGTT CAAAAGTAAAAACGTTTAAACAATACTATGAAGAGCAGTCTGGTGGTAGTTATACGACAGATGGATATGTAACGGAGTGG CTAACTGTTCCAGGAAAAGCATCTGATTATGGGGCTGATGGTAGCAGTGGTCACGATAATAAAGGTCCAAAGGGTGCACG TGATTTAGTGAAAGAAGCTTTGCATGCAGCTGCTGAGAAAGGACTAGATTTATCCCAGTTTGATCAATTTGATAGATATG ATACAAACGGGGACGGGAATCAAAATGAACCTGACGGTGTAATTGATCATTTAATGGTAATCCATGCTGGTGTTGGTCAA GAAGCTGGTGGCGGTAAATTAGGTGATGATGCAATCTGGTCACATCGTTCAAAATTATCAGTAGATCCAGTAGCGATTGA AGGTACGAAATCAAAGGTAGATTACTTTGGTGGTAAAGTAGCAGCACATGATTACACAATTGAACCAGAAGATGGAGCTG TAGGTGTGTTTGCACATGAATTTGGACATGATCTTGGATTACCAGATGAATATGACACGAAATATACTGGAAATGGTTCA CCAGTCGAAGCTTGGTCATTAATGAGTGGAGGTAGTTGGACAGGGAAAATCGCAGGAACAGAGCCGACTAGTTTTTCACC ACAAAATAAAGATTTCTTACAAAAGAATATGGGTGGCAACTGGGCAAAAATATTAGAAGTAGATTACGATAAAATTAAGA GTGGTGTGGGAGTTCCTACCTATATTGATCAAAGTGTTACGAAATCAAATCGTCCAGGAGTTGTACGTGTTAACTTACCA GGTAAAAGTGTTGAAACGATTAAACCGGAGTTTGGAAAGCATGCATATTATAGTACAAGAGGCGATGATATGCATACAAC GTTAGAGACACCATTCTTTGATTTAACGAAAGGAACAAATGCAAAATTCGATTATAAAGCAAATTATGAGTTAGAAGCAG AGTGCGATTTCGTCGAAGTACATGCAGTAACAGAAGATGGAACGAAAACATTAATTGATAGACTTGGGGAAAAAGTAGTC CAAGGAGATAAAGATACAACAGATGGGAAATGGATTGATAAATCATATGATTTAAGTCAATTTAAAGGCAAAAAAGTGAA ACTACAATTCGACTATATTACAGATCCGGCTGTAACATATAAAGGTTTTGCGATGGATAATGTAAATGTAACTGTTGATG GACAAGTTGTATTTTCTGATGATGTAGAAGGACAGTCTAAAATGAATTTAAATGGTTTTGTTGTTTCTGATGGGACAGAG AAGAAAGCTCATTATTACTACTTAGAGTGGAGAAACTATGCGGGATCAGATAATGGTTTAAAAGCAGGAAAAGGTCCAGT GTATAATACAGGCCTTGTCGTTTGGTATGCAGATGATAGTTTCAAAGATAACTGGGTTGGGATGCATCCAGGTGAAGGAT TCCTGGGTGTTGTAGATTCTCATCCAGAAGCGCTAGTTGGTAATTTAAACGGAAAACCAGCATACGGTAATACGGGCATG CAAATTGCAGATGCTGCATTTTCATTTGATAAAACACCAGCATGGAGTGTAAATTCATTAACACGTGGTCAGTTTAACTA TTCTGGATTACAAGGTGTTACAACTTTTGATGATTCAAAAGTATATAGTAACAAGCAAATTGCAGACGCAGGAAGAAAAG TTCCAAACCTTGGACTTAAATTCCAAGTTGTTGGACAGGCAGAAGATAAATCGGCAGGCGCTGTTTGGATTAAACGTTAA
Upstream 100 bases:
>100_bases GAATTATGCCTTTTTATATAGGGAGGGTAGTAAACGGGGATTTCGACAAAAATGTACTTATTTATCTGAATTTTAAGTTT TATAAAAGGAGAGAAATGGA
Downstream 100 bases:
>100_bases TAACATAAAAGCACATTCTTCATATGAAGAGTGTGCTTTTTGATTTGTACAGTAAGTTATTATTTTAGTTTATCCCGCAT TAACGGTCAGTAAGATCCCC
Product: immune inhibitor A metalloprotease
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 799; Mature: 799
Protein sequence:
>799_residues MRRKAPFKVLSSLAIAAIIGCTSVMSAPLTYAETPAKEKDNVSTTPIDYNLIQEDRLAEALKERGTINPASSKEETKKAV EQYIEKKQGDQANKEILPDAHSQETSDFTKKVKEKKMEEKENVKKAEKNVSLEQKPEPNKKQLNGQVPTSKAKQAPYKGS VRSDKVLVLLVEFSDYKHNNIDQTPGYMYSKDFSREHYQKMLFGNEPYTLFDGSKVKTFKQYYEEQSGGSYTTDGYVTEW LTVPGKASDYGADGSSGHDNKGPKGARDLVKEALHAAAEKGLDLSQFDQFDRYDTNGDGNQNEPDGVIDHLMVIHAGVGQ EAGGGKLGDDAIWSHRSKLSVDPVAIEGTKSKVDYFGGKVAAHDYTIEPEDGAVGVFAHEFGHDLGLPDEYDTKYTGNGS PVEAWSLMSGGSWTGKIAGTEPTSFSPQNKDFLQKNMGGNWAKILEVDYDKIKSGVGVPTYIDQSVTKSNRPGVVRVNLP GKSVETIKPEFGKHAYYSTRGDDMHTTLETPFFDLTKGTNAKFDYKANYELEAECDFVEVHAVTEDGTKTLIDRLGEKVV QGDKDTTDGKWIDKSYDLSQFKGKKVKLQFDYITDPAVTYKGFAMDNVNVTVDGQVVFSDDVEGQSKMNLNGFVVSDGTE KKAHYYYLEWRNYAGSDNGLKAGKGPVYNTGLVVWYADDSFKDNWVGMHPGEGFLGVVDSHPEALVGNLNGKPAYGNTGM QIADAAFSFDKTPAWSVNSLTRGQFNYSGLQGVTTFDDSKVYSNKQIADAGRKVPNLGLKFQVVGQAEDKSAGAVWIKR
Sequences:
>Translated_799_residues MRRKAPFKVLSSLAIAAIIGCTSVMSAPLTYAETPAKEKDNVSTTPIDYNLIQEDRLAEALKERGTINPASSKEETKKAV EQYIEKKQGDQANKEILPDAHSQETSDFTKKVKEKKMEEKENVKKAEKNVSLEQKPEPNKKQLNGQVPTSKAKQAPYKGS VRSDKVLVLLVEFSDYKHNNIDQTPGYMYSKDFSREHYQKMLFGNEPYTLFDGSKVKTFKQYYEEQSGGSYTTDGYVTEW LTVPGKASDYGADGSSGHDNKGPKGARDLVKEALHAAAEKGLDLSQFDQFDRYDTNGDGNQNEPDGVIDHLMVIHAGVGQ EAGGGKLGDDAIWSHRSKLSVDPVAIEGTKSKVDYFGGKVAAHDYTIEPEDGAVGVFAHEFGHDLGLPDEYDTKYTGNGS PVEAWSLMSGGSWTGKIAGTEPTSFSPQNKDFLQKNMGGNWAKILEVDYDKIKSGVGVPTYIDQSVTKSNRPGVVRVNLP GKSVETIKPEFGKHAYYSTRGDDMHTTLETPFFDLTKGTNAKFDYKANYELEAECDFVEVHAVTEDGTKTLIDRLGEKVV QGDKDTTDGKWIDKSYDLSQFKGKKVKLQFDYITDPAVTYKGFAMDNVNVTVDGQVVFSDDVEGQSKMNLNGFVVSDGTE KKAHYYYLEWRNYAGSDNGLKAGKGPVYNTGLVVWYADDSFKDNWVGMHPGEGFLGVVDSHPEALVGNLNGKPAYGNTGM QIADAAFSFDKTPAWSVNSLTRGQFNYSGLQGVTTFDDSKVYSNKQIADAGRKVPNLGLKFQVVGQAEDKSAGAVWIKR >Mature_799_residues MRRKAPFKVLSSLAIAAIIGCTSVMSAPLTYAETPAKEKDNVSTTPIDYNLIQEDRLAEALKERGTINPASSKEETKKAV EQYIEKKQGDQANKEILPDAHSQETSDFTKKVKEKKMEEKENVKKAEKNVSLEQKPEPNKKQLNGQVPTSKAKQAPYKGS VRSDKVLVLLVEFSDYKHNNIDQTPGYMYSKDFSREHYQKMLFGNEPYTLFDGSKVKTFKQYYEEQSGGSYTTDGYVTEW LTVPGKASDYGADGSSGHDNKGPKGARDLVKEALHAAAEKGLDLSQFDQFDRYDTNGDGNQNEPDGVIDHLMVIHAGVGQ EAGGGKLGDDAIWSHRSKLSVDPVAIEGTKSKVDYFGGKVAAHDYTIEPEDGAVGVFAHEFGHDLGLPDEYDTKYTGNGS PVEAWSLMSGGSWTGKIAGTEPTSFSPQNKDFLQKNMGGNWAKILEVDYDKIKSGVGVPTYIDQSVTKSNRPGVVRVNLP GKSVETIKPEFGKHAYYSTRGDDMHTTLETPFFDLTKGTNAKFDYKANYELEAECDFVEVHAVTEDGTKTLIDRLGEKVV QGDKDTTDGKWIDKSYDLSQFKGKKVKLQFDYITDPAVTYKGFAMDNVNVTVDGQVVFSDDVEGQSKMNLNGFVVSDGTE KKAHYYYLEWRNYAGSDNGLKAGKGPVYNTGLVVWYADDSFKDNWVGMHPGEGFLGVVDSHPEALVGNLNGKPAYGNTGM QIADAAFSFDKTPAWSVNSLTRGQFNYSGLQGVTTFDDSKVYSNKQIADAGRKVPNLGLKFQVVGQAEDKSAGAVWIKR
Specific function: Neutral metalloprotease that is secreted to degrade antibacterial proteins produced by the insect host for its defense (attacins and cecropins). Probably degrades some unknown crucial protein(s) too, since it is toxic when injected to insect larvae [H]
COG id: COG4412
COG function: function code S; Uncharacterized protein conserved in bacteria
Gene ontology:
Cell location: Secreted [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the peptidase M6 family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012300 - InterPro: IPR008757 [H]
Pfam domain/function: PF05547 Peptidase_M6 [H]
EC number: NA
Molecular weight: Translated: 87977; Mature: 87977
Theoretical pI: Translated: 5.50; Mature: 5.50
Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00142 ZINC_PROTEASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 1.9 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 1.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRRKAPFKVLSSLAIAAIIGCTSVMSAPLTYAETPAKEKDNVSTTPIDYNLIQEDRLAEA CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH LKERGTINPASSKEETKKAVEQYIEKKQGDQANKEILPDAHSQETSDFTKKVKEKKMEEK HHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHH ENVKKAEKNVSLEQKPEPNKKQLNGQVPTSKAKQAPYKGSVRSDKVLVLLVEFSDYKHNN HHHHHHHHCCCCCCCCCCCHHHCCCCCCCCHHHCCCCCCCCCCCCEEEEEEEECCCCCCC IDQTPGYMYSKDFSREHYQKMLFGNEPYTLFDGSKVKTFKQYYEEQSGGSYTTDGYVTEW CCCCCCCCCCCCCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCEEEEE LTVPGKASDYGADGSSGHDNKGPKGARDLVKEALHAAAEKGLDLSQFDQFDRYDTNGDGN EECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCC QNEPDGVIDHLMVIHAGVGQEAGGGKLGDDAIWSHRSKLSVDPVAIEGTKSKVDYFGGKV CCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCCCCEEECCCCCHHHHCCCEE AAHDYTIEPEDGAVGVFAHEFGHDLGLPDEYDTKYTGNGSPVEAWSLMSGGSWTGKIAGT EECCEEECCCCCEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCC EPTSFSPQNKDFLQKNMGGNWAKILEVDYDKIKSGVGVPTYIDQSVTKSNRPGVVRVNLP CCCCCCCCCHHHHHHCCCCCEEEEEECCHHHHHCCCCCCHHHCHHHHCCCCCCEEEEECC GKSVETIKPEFGKHAYYSTRGDDMHTTLETPFFDLTKGTNAKFDYKANYELEAECDFVEV CCCCHHCCCCCCCCCEEECCCCCCEEECCCCCEEECCCCCCEEEEECCCEEECCCCEEEE HAVTEDGTKTLIDRLGEKVVQGDKDTTDGKWIDKSYDLSQFKGKKVKLQFDYITDPAVTY EEECCCCHHHHHHHHHHHHHCCCCCCCCCCEECCCCCHHHCCCCEEEEEEEEECCCCEEE KGFAMDNVNVTVDGQVVFSDDVEGQSKMNLNGFVVSDGTEKKAHYYYLEWRNYAGSDNGL ECEEECCEEEEECCEEEECCCCCCCCEECCCEEEEECCCCCCEEEEEEEEECCCCCCCCC KAGKGPVYNTGLVVWYADDSFKDNWVGMHPGEGFLGVVDSHPEALVGNLNGKPAYGNTGM CCCCCCCEECCEEEEEECCCCCCCEEECCCCCCEEEEECCCCCCEEECCCCCCCCCCCCC QIADAAFSFDKTPAWSVNSLTRGQFNYSGLQGVTTFDDSKVYSNKQIADAGRKVPNLGLK EEEHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCHHCCCCHHHHHCCCCCCCCEE FQVVGQAEDKSAGAVWIKR EEEEECCCCCCCCEEEEEC >Mature Secondary Structure MRRKAPFKVLSSLAIAAIIGCTSVMSAPLTYAETPAKEKDNVSTTPIDYNLIQEDRLAEA CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH LKERGTINPASSKEETKKAVEQYIEKKQGDQANKEILPDAHSQETSDFTKKVKEKKMEEK HHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHH ENVKKAEKNVSLEQKPEPNKKQLNGQVPTSKAKQAPYKGSVRSDKVLVLLVEFSDYKHNN HHHHHHHHCCCCCCCCCCCHHHCCCCCCCCHHHCCCCCCCCCCCCEEEEEEEECCCCCCC IDQTPGYMYSKDFSREHYQKMLFGNEPYTLFDGSKVKTFKQYYEEQSGGSYTTDGYVTEW CCCCCCCCCCCCCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCEEEEE LTVPGKASDYGADGSSGHDNKGPKGARDLVKEALHAAAEKGLDLSQFDQFDRYDTNGDGN EECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCC QNEPDGVIDHLMVIHAGVGQEAGGGKLGDDAIWSHRSKLSVDPVAIEGTKSKVDYFGGKV CCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCCCCEEECCCCCHHHHCCCEE AAHDYTIEPEDGAVGVFAHEFGHDLGLPDEYDTKYTGNGSPVEAWSLMSGGSWTGKIAGT EECCEEECCCCCEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCC EPTSFSPQNKDFLQKNMGGNWAKILEVDYDKIKSGVGVPTYIDQSVTKSNRPGVVRVNLP CCCCCCCCCHHHHHHCCCCCEEEEEECCHHHHHCCCCCCHHHCHHHHCCCCCCEEEEECC GKSVETIKPEFGKHAYYSTRGDDMHTTLETPFFDLTKGTNAKFDYKANYELEAECDFVEV CCCCHHCCCCCCCCCEEECCCCCCEEECCCCCEEECCCCCCEEEEECCCEEECCCCEEEE HAVTEDGTKTLIDRLGEKVVQGDKDTTDGKWIDKSYDLSQFKGKKVKLQFDYITDPAVTY EEECCCCHHHHHHHHHHHHHCCCCCCCCCCEECCCCCHHHCCCCEEEEEEEEECCCCEEE KGFAMDNVNVTVDGQVVFSDDVEGQSKMNLNGFVVSDGTEKKAHYYYLEWRNYAGSDNGL ECEEECCEEEEECCEEEECCCCCCCCEECCCEEEEECCCCCCEEEEEEEEECCCCCCCCC KAGKGPVYNTGLVVWYADDSFKDNWVGMHPGEGFLGVVDSHPEALVGNLNGKPAYGNTGM CCCCCCCEECCEEEEEECCCCCCCEEECCCCCCEEEEECCCCCCEEECCCCCCCCCCCCC QIADAAFSFDKTPAWSVNSLTRGQFNYSGLQGVTTFDDSKVYSNKQIADAGRKVPNLGLK EEEHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCHHCCCCHHHHHCCCCCCCCEE FQVVGQAEDKSAGAVWIKR EEEEECCCCCCCCEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 2089225; 6421577 [H]