Click here to switch to the map view.

The map label for this gene is galE [H]

Identifier: 218235281

GI number: 218235281

Start: 3759458

End: 3760369

Strand: Reverse

Name: galE [H]

Synonym: BCB4264_A3850

Alternate gene names: 218235281

Gene position: 3760369-3759458 (Counterclockwise)

Preceding gene: 218234710

Following gene: 218235895

Centisome position: 69.39

GC content: 33.66

Gene sequence:

>912_bases
ATGAAAAAAAATGCGAGCCTTTTAATAACTGGTGCAAATGGTTTCACAGGACGCCATGCTTGCCACTATTTTTTAGAGCA
GGGCTTTCATGTAATTCCTATGTTTCAAAATCGTGCACATAGAGAAAAAATTAGAAATGGTATTACGTGTAATTTAACTA
ATAAGAGCGAAGTAATGAAGGTAATGAAACAAATAAAGCCAGACTACGTATTGCATTTAGCAGGAAGGAATTCGGTTATA
GAATCTTGGACAGCTGCTCTTGAGTATATAGAGATTAATGTAATAGGAACGTTATATTTATTAGAAGCAATTAAGCAAGA
AGCCTCGCATTGTAGAACATTAGTTATAGGATCTGCTTTGCAAACAGATAGTATGAACGAAATAAAAATTTCAAATCCAT
ATAGTTTAAGTAAAACGATGCAAGTCATTATTGCAGAGGCTTGGGGAGGATTAATGGATTCAAATATTATCATTGCAAAG
CCCTCAAACTTAATTGGCCCAGGGGAATCGAATGGCATTTGTTCGATTCTCGCAAAGAAAATGATAGATATAGAATCAGG
TAGAAGTAAAGCCATTATTGAAGTAAACAGTTTGAAAGATAGTAGAGATTTTCTAGATGTACGTGATGCGATTAAAGCGT
ATCATGTGTTATTACGAGATGGAATAAATGGAAAACAATATAATATCGGATCAGGAGTAAAACGATCTTTATTAGATGTA
CTAGAACAATATAAAGAATTAACACAGCTAAATTTTTTTATAGAGGAAACAGAGAAAAGTGGGAGCGACTCAAATGAGAG
TTTAGCAACAGAGGAAATAAAAAAGTTAGGTTGGATCCCAGAAATTGAATTTCATCAATCATTAAAAGATGTACTTGAGT
ATGCGAAGTGTAGTGACATCTGCATGCAATGA

Upstream 100 bases:

>100_bases
CTAGCTATCCGCTAGTGGATGTGAAGAGTTTTAGTTCTCAACAAGACTTGCTTGCAAAACATGAGGTGAAACAAATGCTA
TTAAAAGGAGGGTTTTTGCG

Downstream 100 bases:

>100_bases
AAAACAAAAAAGGGTGTAAGAAATATATGAATGGTTATGAAGTAATAGATAATCAAAATACGCTATTTCTTTCAATTGTT
GATACGCTGGACTGGAGAGA

Product: UDP-2-acetamido-2,6-dideoxy-hexulose 4-reductase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MKKNASLLITGANGFTGRHACHYFLEQGFHVIPMFQNRAHREKIRNGITCNLTNKSEVMKVMKQIKPDYVLHLAGRNSVI
ESWTAALEYIEINVIGTLYLLEAIKQEASHCRTLVIGSALQTDSMNEIKISNPYSLSKTMQVIIAEAWGGLMDSNIIIAK
PSNLIGPGESNGICSILAKKMIDIESGRSKAIIEVNSLKDSRDFLDVRDAIKAYHVLLRDGINGKQYNIGSGVKRSLLDV
LEQYKELTQLNFFIEETEKSGSDSNESLATEEIKKLGWIPEIEFHQSLKDVLEYAKCSDICMQ

Sequences:

>Translated_303_residues
MKKNASLLITGANGFTGRHACHYFLEQGFHVIPMFQNRAHREKIRNGITCNLTNKSEVMKVMKQIKPDYVLHLAGRNSVI
ESWTAALEYIEINVIGTLYLLEAIKQEASHCRTLVIGSALQTDSMNEIKISNPYSLSKTMQVIIAEAWGGLMDSNIIIAK
PSNLIGPGESNGICSILAKKMIDIESGRSKAIIEVNSLKDSRDFLDVRDAIKAYHVLLRDGINGKQYNIGSGVKRSLLDV
LEQYKELTQLNFFIEETEKSGSDSNESLATEEIKKLGWIPEIEFHQSLKDVLEYAKCSDICMQ
>Mature_303_residues
MKKNASLLITGANGFTGRHACHYFLEQGFHVIPMFQNRAHREKIRNGITCNLTNKSEVMKVMKQIKPDYVLHLAGRNSVI
ESWTAALEYIEINVIGTLYLLEAIKQEASHCRTLVIGSALQTDSMNEIKISNPYSLSKTMQVIIAEAWGGLMDSNIIIAK
PSNLIGPGESNGICSILAKKMIDIESGRSKAIIEVNSLKDSRDFLDVRDAIKAYHVLLRDGINGKQYNIGSGVKRSLLDV
LEQYKELTQLNFFIEETEKSGSDSNESLATEEIKKLGWIPEIEFHQSLKDVLEYAKCSDICMQ

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI7657641, Length=250, Percent_Identity=26.4, Blast_Score=79, Evalue=5e-15,
Organism=Escherichia coli, GI48994969, Length=339, Percent_Identity=24.188790560472, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788353, Length=289, Percent_Identity=24.2214532871972, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786974, Length=314, Percent_Identity=22.6114649681529, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=339, Percent_Identity=25.3687315634218, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 33928; Mature: 33928

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNASLLITGANGFTGRHACHYFLEQGFHVIPMFQNRAHREKIRNGITCNLTNKSEVMK
CCCCCCEEEECCCCCCHHHHHHHHHHCCCEEEEHHHCHHHHHHHHCCCEEEECCHHHHHH
VMKQIKPDYVLHLAGRNSVIESWTAALEYIEINVIGTLYLLEAIKQEASHCRTLVIGSAL
HHHHCCCCEEEEECCCCHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHCCCHH
QTDSMNEIKISNPYSLSKTMQVIIAEAWGGLMDSNIIIAKPSNLIGPGESNGICSILAKK
CCCCCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHH
MIDIESGRSKAIIEVNSLKDSRDFLDVRDAIKAYHVLLRDGINGKQYNIGSGVKRSLLDV
HHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHH
LEQYKELTQLNFFIEETEKSGSDSNESLATEEIKKLGWIPEIEFHQSLKDVLEYAKCSDI
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
CMQ
HCC
>Mature Secondary Structure
MKKNASLLITGANGFTGRHACHYFLEQGFHVIPMFQNRAHREKIRNGITCNLTNKSEVMK
CCCCCCEEEECCCCCCHHHHHHHHHHCCCEEEEHHHCHHHHHHHHCCCEEEECCHHHHHH
VMKQIKPDYVLHLAGRNSVIESWTAALEYIEINVIGTLYLLEAIKQEASHCRTLVIGSAL
HHHHCCCCEEEEECCCCHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHCCCHH
QTDSMNEIKISNPYSLSKTMQVIIAEAWGGLMDSNIIIAKPSNLIGPGESNGICSILAKK
CCCCCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHH
MIDIESGRSKAIIEVNSLKDSRDFLDVRDAIKAYHVLLRDGINGKQYNIGSGVKRSLLDV
HHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHH
LEQYKELTQLNFFIEETEKSGSDSNESLATEEIKKLGWIPEIEFHQSLKDVLEYAKCSDI
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
CMQ
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8932701 [H]