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The map label for this gene is ydfD [H]

Identifier: 218235279

GI number: 218235279

Start: 2603979

End: 2605364

Strand: Reverse

Name: ydfD [H]

Synonym: BCB4264_A2693

Alternate gene names: 218235279

Gene position: 2605364-2603979 (Counterclockwise)

Preceding gene: 218231949

Following gene: 218233844

Centisome position: 48.08

GC content: 33.84

Gene sequence:

>1386_bases
ATGAAAGAAAAAATTGAAAACAGAGAATGGCCAATTGGAAGTAAAATCCCTAGTCAGCGGCAGTTAGCAAAATTATTTCA
TGTAAATCGAAGTACTGTAATAAATGCGCTAGATGAACTTATGGCAGATGGTTTAATTCAAGGACAAATCGGAGCAGGAA
CAATTGTAACAAATAATACATGGTCATTATTAGCAACTAATCCCCCGCCCGATTGGAGTGAATATGTAAAGGCCGGTATT
CATAAACCAAGTAAGTTAATGGTGCGAGAAATAAATGAAGCAGAAGCAAATAAAACGCTTATCCATCTTAGTAAAGGTGA
ACTTGCACCTCACCTTTTCCCGCTCGAAACTATGCAATCTATAATTAAAAACGTCAGTGAGGAATTAGATTATTTCGGAT
ACGAAGAACAAAAAGGTTTTTATCCGTTACGTGAAGCAATAAGCAAATACGTAAAATCATTTGGAATACATGCATCACCG
GGTTCTATATTAATAGTCTCTGGTGCACTCCAAGCATTACAATTAATATCAATTGGTCTTTTACATAGAAAATCAACTGT
TTTACTTGAACAACCTTCTTACTTATATTCACTTCATGTTTTTCAATCAGCAAATATAAATTTATCCGGTATATCAATGG
ATCATCACGGTATTTTACCTAACGACTTATTAAAACGAATTAAATATAGTCAAAAGAATAATATTTTATATTCAATCCCT
TGTTTTCAAAATCCAACGGGGATATTGATGTCCAAAGAGCGAAGAAAAGAAATATTAAAAATATGTGAAAAAGAGCAATT
GCCTATCATCGAGGATGATATTTACCGAGAGTTATGGCTTGATGAATCACCTCCAGCTCCTTTAAAGTCGATGGATAAAC
ATGGACATGTATTATATATTGGTAGTCTCTCTAAAACACTTAGCCCAGGACTTAGAATTGGATGGATAATTGGACCAGAA
CCTGTTATTGATAGATTGTCAGATATAAAAATGCAAACAGACTATGGATCCAGCTCTTTATCTCAAAGAGTAGCTGCTGA
ATGGATAAATGAAGGTTTTTATGAAGCACATGTAGCAAACGTAAGAATGCACCTGAAAGAACGAAGACAAATAATGATAC
GAGCTTTAAATAAATATTGTGCAGATATTGCATCATGGGATATTCCTATTGGTGGATTTTTTATATGGCTAAAGGTTGTA
CATAACATTCCGATGAAAAAACTATTTTCAGAGGCACTATCAAAAGGAATTCTTTTAAATCCGGGACGTATTTATGAAGA
AGAATCAGATCAGTACATTCGTTTATCATATGGATATGCTACTCCAGAACAAATGACTAACGGAATTAAATTGCTCAGTG
AATTAATTCGGAAGTTAACGGCATAA

Upstream 100 bases:

>100_bases
TCGGAAAAACCAACCACTTTGAATCTTTTAAATAAACGAAGGAGTTTTTTATATGACAACCGATAAAAAAGTGCCCAAAT
ATCGGCAGATAATAGACTAT

Downstream 100 bases:

>100_bases
AAAAATCCTCTTTTGTTTTTGGAGGATTTTTTTATGTATCTTATTTACCACAATTTCATTTCCTGCCCTAATAAAATAAG
TTCTTCATAAGGATCTCCGT

Product: transcriptional regulator, GntR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MKEKIENREWPIGSKIPSQRQLAKLFHVNRSTVINALDELMADGLIQGQIGAGTIVTNNTWSLLATNPPPDWSEYVKAGI
HKPSKLMVREINEAEANKTLIHLSKGELAPHLFPLETMQSIIKNVSEELDYFGYEEQKGFYPLREAISKYVKSFGIHASP
GSILIVSGALQALQLISIGLLHRKSTVLLEQPSYLYSLHVFQSANINLSGISMDHHGILPNDLLKRIKYSQKNNILYSIP
CFQNPTGILMSKERRKEILKICEKEQLPIIEDDIYRELWLDESPPAPLKSMDKHGHVLYIGSLSKTLSPGLRIGWIIGPE
PVIDRLSDIKMQTDYGSSSLSQRVAAEWINEGFYEAHVANVRMHLKERRQIMIRALNKYCADIASWDIPIGGFFIWLKVV
HNIPMKKLFSEALSKGILLNPGRIYEEESDQYIRLSYGYATPEQMTNGIKLLSELIRKLTA

Sequences:

>Translated_461_residues
MKEKIENREWPIGSKIPSQRQLAKLFHVNRSTVINALDELMADGLIQGQIGAGTIVTNNTWSLLATNPPPDWSEYVKAGI
HKPSKLMVREINEAEANKTLIHLSKGELAPHLFPLETMQSIIKNVSEELDYFGYEEQKGFYPLREAISKYVKSFGIHASP
GSILIVSGALQALQLISIGLLHRKSTVLLEQPSYLYSLHVFQSANINLSGISMDHHGILPNDLLKRIKYSQKNNILYSIP
CFQNPTGILMSKERRKEILKICEKEQLPIIEDDIYRELWLDESPPAPLKSMDKHGHVLYIGSLSKTLSPGLRIGWIIGPE
PVIDRLSDIKMQTDYGSSSLSQRVAAEWINEGFYEAHVANVRMHLKERRQIMIRALNKYCADIASWDIPIGGFFIWLKVV
HNIPMKKLFSEALSKGILLNPGRIYEEESDQYIRLSYGYATPEQMTNGIKLLSELIRKLTA
>Mature_461_residues
MKEKIENREWPIGSKIPSQRQLAKLFHVNRSTVINALDELMADGLIQGQIGAGTIVTNNTWSLLATNPPPDWSEYVKAGI
HKPSKLMVREINEAEANKTLIHLSKGELAPHLFPLETMQSIIKNVSEELDYFGYEEQKGFYPLREAISKYVKSFGIHASP
GSILIVSGALQALQLISIGLLHRKSTVLLEQPSYLYSLHVFQSANINLSGISMDHHGILPNDLLKRIKYSQKNNILYSIP
CFQNPTGILMSKERRKEILKICEKEQLPIIEDDIYRELWLDESPPAPLKSMDKHGHVLYIGSLSKTLSPGLRIGWIIGPE
PVIDRLSDIKMQTDYGSSSLSQRVAAEWINEGFYEAHVANVRMHLKERRQIMIRALNKYCADIASWDIPIGGFFIWLKVV
HNIPMKKLFSEALSKGILLNPGRIYEEESDQYIRLSYGYATPEQMTNGIKLLSELIRKLTA

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=425, Percent_Identity=29.1764705882353, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI33469970, Length=425, Percent_Identity=29.1764705882353, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI4507369, Length=260, Percent_Identity=27.6923076923077, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI1787710, Length=465, Percent_Identity=25.1612903225806, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1790797, Length=468, Percent_Identity=26.0683760683761, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1788722, Length=330, Percent_Identity=23.6363636363636, Blast_Score=78, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321236, Length=359, Percent_Identity=23.6768802228412, Blast_Score=98, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6321000, Length=249, Percent_Identity=26.5060240963855, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21356535, Length=360, Percent_Identity=24.1666666666667, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI18859735, Length=214, Percent_Identity=28.0373831775701, Blast_Score=79, Evalue=6e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 52254; Mature: 52254

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEKIENREWPIGSKIPSQRQLAKLFHVNRSTVINALDELMADGLIQGQIGAGTIVTNNT
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCEECCCCCCEEEECCC
WSLLATNPPPDWSEYVKAGIHKPSKLMVREINEAEANKTLIHLSKGELAPHLFPLETMQS
EEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCEECHHHHHH
IIKNVSEELDYFGYEEQKGFYPLREAISKYVKSFGIHASPGSILIVSGALQALQLISIGL
HHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHH
LHRKSTVLLEQPSYLYSLHVFQSANINLSGISMDHHGILPNDLLKRIKYSQKNNILYSIP
HHCCCEEEEECCCCEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEC
CFQNPTGILMSKERRKEILKICEKEQLPIIEDDIYRELWLDESPPAPLKSMDKHGHVLYI
CCCCCCCCEECHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHCCCCCEEEE
GSLSKTLSPGLRIGWIIGPEPVIDRLSDIKMQTDYGSSSLSQRVAAEWINEGFYEAHVAN
ECCHHHCCCCCEEEEEECCHHHHHHHHHCEEECCCCCHHHHHHHHHHHHHCCHHHHHHHH
VRMHLKERRQIMIRALNKYCADIASWDIPIGGFFIWLKVVHNIPMKKLFSEALSKGILLN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEC
PGRIYEEESDQYIRLSYGYATPEQMTNGIKLLSELIRKLTA
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKEKIENREWPIGSKIPSQRQLAKLFHVNRSTVINALDELMADGLIQGQIGAGTIVTNNT
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCEECCCCCCEEEECCC
WSLLATNPPPDWSEYVKAGIHKPSKLMVREINEAEANKTLIHLSKGELAPHLFPLETMQS
EEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCEECHHHHHH
IIKNVSEELDYFGYEEQKGFYPLREAISKYVKSFGIHASPGSILIVSGALQALQLISIGL
HHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHH
LHRKSTVLLEQPSYLYSLHVFQSANINLSGISMDHHGILPNDLLKRIKYSQKNNILYSIP
HHCCCEEEEECCCCEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEC
CFQNPTGILMSKERRKEILKICEKEQLPIIEDDIYRELWLDESPPAPLKSMDKHGHVLYI
CCCCCCCCEECHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHCCCCCEEEE
GSLSKTLSPGLRIGWIIGPEPVIDRLSDIKMQTDYGSSSLSQRVAAEWINEGFYEAHVAN
ECCHHHCCCCCEEEEEECCHHHHHHHHHCEEECCCCCHHHHHHHHHHHHHCCHHHHHHHH
VRMHLKERRQIMIRALNKYCADIASWDIPIGGFFIWLKVVHNIPMKKLFSEALSKGILLN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEC
PGRIYEEESDQYIRLSYGYATPEQMTNGIKLLSELIRKLTA
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]