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The map label for this gene is mecA [H]

Identifier: 218235246

GI number: 218235246

Start: 1211813

End: 1212496

Strand: Direct

Name: mecA [H]

Synonym: BCB4264_A1244

Alternate gene names: 218235246

Gene position: 1211813-1212496 (Clockwise)

Preceding gene: 218231586

Following gene: 218235896

Centisome position: 22.36

GC content: 34.5

Gene sequence:

>684_bases
TTGGATATTGAAAGAATTAATGATCATACGATGAAATTTTTTATTACGTACATTGATATAGAGGATAGAGGATTTAATCG
TGAAGAAATTTGGTATGATCGCGAACGAAGTGAAGAGCTCTTTTGGGAGATGATGGACGAAGCTCGTGATCATGACGATT
TCTTTATTGATGGACCGTTATGGATTCAAGTGCAAGCAGTCGATAAAGGGATTGAAGTACTTGTCACGAAAGCAGAGCTT
TCAAAGGACGGACAAAAGCTGGAACTACCGATAGGGGTAGACAAAATTATAGATATTCCTCTAGATGAAGGCATCGAATC
ATTATTCCAACAAGAATTAGTCGAAGAGGTAGAAGAACAAACAGGAACAAACTTTAATGAAGATGGTACGTTTGGCTTTT
TAATTAAATTTAATGATTTTGAAGATGTCATTTCATTAAGTCATCGTCTTATCTTTGAAGATATAAAAGATGAGCTGTAT
TCATTTGAGGACCGCTATTATGTATATGTGGAATTCGATGAAGTGCTACATGATGAAGAAGAAATCGATCGTATTTTAAG
TATTATTTTAGAATATGGAGAAGAATCAACTTTAACAATTCATCGTGTAAGTGAGTATGGAAAACAAATTGTGAAAGAGC
ATGCGCTTGAAACGATTCGCAATAATTTTCCTGCTAAAACGTAG

Upstream 100 bases:

>100_bases
AGAATCTTATCATAAAATGAGAGTACAAGAATCTATTGATTTGTCATATGAGTGGGGAATCCCTTCATAACAATTCTAAG
CAGGAAGGGAGAGTTGTATT

Downstream 100 bases:

>100_bases
GCCGATTTCTGTAGTATGAAATCGGCTTTTTATATGAAGAATAGGAAAGCTTTCTTAGTTAGGAGGTAAGAGATGAAAAA
TACGTTAAAGCTGATTTTCT

Product: adaptor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MDIERINDHTMKFFITYIDIEDRGFNREEIWYDRERSEELFWEMMDEARDHDDFFIDGPLWIQVQAVDKGIEVLVTKAEL
SKDGQKLELPIGVDKIIDIPLDEGIESLFQQELVEEVEEQTGTNFNEDGTFGFLIKFNDFEDVISLSHRLIFEDIKDELY
SFEDRYYVYVEFDEVLHDEEEIDRILSIILEYGEESTLTIHRVSEYGKQIVKEHALETIRNNFPAKT

Sequences:

>Translated_227_residues
MDIERINDHTMKFFITYIDIEDRGFNREEIWYDRERSEELFWEMMDEARDHDDFFIDGPLWIQVQAVDKGIEVLVTKAEL
SKDGQKLELPIGVDKIIDIPLDEGIESLFQQELVEEVEEQTGTNFNEDGTFGFLIKFNDFEDVISLSHRLIFEDIKDELY
SFEDRYYVYVEFDEVLHDEEEIDRILSIILEYGEESTLTIHRVSEYGKQIVKEHALETIRNNFPAKT
>Mature_227_residues
MDIERINDHTMKFFITYIDIEDRGFNREEIWYDRERSEELFWEMMDEARDHDDFFIDGPLWIQVQAVDKGIEVLVTKAEL
SKDGQKLELPIGVDKIIDIPLDEGIESLFQQELVEEVEEQTGTNFNEDGTFGFLIKFNDFEDVISLSHRLIFEDIKDELY
SFEDRYYVYVEFDEVLHDEEEIDRILSIILEYGEESTLTIHRVSEYGKQIVKEHALETIRNNFPAKT

Specific function: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When ove

COG id: COG4862

COG function: function code OTN; Negative regulator of genetic competence, sporulation and motility

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mecA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008681 [H]

Pfam domain/function: PF05389 MecA [H]

EC number: NA

Molecular weight: Translated: 27010; Mature: 27010

Theoretical pI: Translated: 3.98; Mature: 3.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIERINDHTMKFFITYIDIEDRGFNREEIWYDRERSEELFWEMMDEARDHDDFFIDGPL
CCCCCCCCCEEEEEEEEEEEECCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCEEECCCE
WIQVQAVDKGIEVLVTKAELSKDGQKLELPIGVDKIIDIPLDEGIESLFQQELVEEVEEQ
EEEEEEECCCEEEEEEHHHHCCCCCEEEECCCHHHHEECCHHHHHHHHHHHHHHHHHHHH
TGTNFNEDGTFGFLIKFNDFEDVISLSHRLIFEDIKDELYSFEDRYYVYVEFDEVLHDEE
HCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHCCHH
EIDRILSIILEYGEESTLTIHRVSEYGKQIVKEHALETIRNNFPAKT
HHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDIERINDHTMKFFITYIDIEDRGFNREEIWYDRERSEELFWEMMDEARDHDDFFIDGPL
CCCCCCCCCEEEEEEEEEEEECCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCEEECCCE
WIQVQAVDKGIEVLVTKAELSKDGQKLELPIGVDKIIDIPLDEGIESLFQQELVEEVEEQ
EEEEEEECCCEEEEEEHHHHCCCCCEEEECCCHHHHEECCHHHHHHHHHHHHHHHHHHHH
TGTNFNEDGTFGFLIKFNDFEDVISLSHRLIFEDIKDELYSFEDRYYVYVEFDEVLHDEE
HCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHCCHH
EIDRILSIILEYGEESTLTIHRVSEYGKQIVKEHALETIRNNFPAKT
HHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]