Click here to switch to the map view.

The map label for this gene is yhfP [H]

Identifier: 218235170

GI number: 218235170

Start: 809025

End: 810020

Strand: Direct

Name: yhfP [H]

Synonym: BCB4264_A0839

Alternate gene names: 218235170

Gene position: 809025-810020 (Clockwise)

Preceding gene: 218233696

Following gene: 218234170

Centisome position: 14.93

GC content: 39.66

Gene sequence:

>996_bases
ATGAATCATACATCATTCCGAGCAATCGTTGTGAACGAAAAGGAAAATCATCAGTTTGTAAGAAAAGTTGTTGAGAGAGA
AGTAAGTAGTTTACCTGAGGGAGACGTATTCATACAAGTTCATTATTCTTCATTAAATTATAAAGATGCTCTTTCAGCTA
CTGGTAATAAGGGTGTTACGAGAACATATCCTCATACGCCAGGAATTGATGCTGCAGGAGTGGTTGTGAGTAGTGAAGAT
GCTACCATTAAAGCAGGAGATCAAGTTATTGTAACGGGATATGACTTAGGTATGAATACCTCTGGTGGTTTCGGAGAATA
TATTCGCGTGCCATCATCTTGGGTCGTGCCTTTACCGGAAGGAATGTCATTAAAGGAAAGTATGATGTATGGGACAGCAG
GTTTTACTGCGGCTTTGTCGGTATATAAGCTTATTGGAGCAGGAATCAAGCCTAGTATGGGAGATGTTTTAGTAACGGGT
GCTACAGGCGGCGTAGGGAGTGTAGCTGTTAGTATATTAAGTAAGTTAGGGTTTAACGTAGTAGGAGCGACAGGAAAAAT
GGAAGAGGAAGATATGCTACTACGTCTAGGAGTGAAAAAAGTGATTCATCGCGCGGAATTGAATGATGAATCAGGAAGAC
CGATGTTAAAAGGGATATACGCGGGAGTTATCGATACTGTAGGTGGACATATGCTAGAAACAGCTTTAAAAACAGTAAAG
TATGGTGGTTGTGTAACGACATGCGGTAATGTGGCAGGCCAGGAACTACAAACAACGGTATATCCGTTTATTTTACGAGG
CATAAGCCTTTTAGGGATAGATTCCGTGCAATGCCCAGTAGATGTGAGAAGAGATGTTTGGACGCTTTTAGCGAAAGAAT
GGGGAAATAAAGAGTTACTATCTTATACAGAAGAATGTACATTAGAAGAATTAGAGAAGAAGTTTGCACTTATATTGCAA
GGAAAGTTAAAAGGAAGAACAGTTGTTAAAATATAA

Upstream 100 bases:

>100_bases
GAAGTAAGATTTGTTGAAATATAGCCAAGAAGAAACGAGTAGGTTTACTAAGTTTTTCTATATAATAAAGAAGAACTTTA
CGGATAAAGGAGAGAGCATA

Downstream 100 bases:

>100_bases
TGAAAAAAGAGACGCTTAAGTTAGCGTCTCTTTCTTATTATAATGATTGTTTTAGATTGATTTTTCCTTGTTCACCTAAA
ACACCGTCAGCGATATTTAC

Product: putative quinone oxidoreductase, YhdH/YhfP family

Products: aldehyde; ketone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MNHTSFRAIVVNEKENHQFVRKVVEREVSSLPEGDVFIQVHYSSLNYKDALSATGNKGVTRTYPHTPGIDAAGVVVSSED
ATIKAGDQVIVTGYDLGMNTSGGFGEYIRVPSSWVVPLPEGMSLKESMMYGTAGFTAALSVYKLIGAGIKPSMGDVLVTG
ATGGVGSVAVSILSKLGFNVVGATGKMEEEDMLLRLGVKKVIHRAELNDESGRPMLKGIYAGVIDTVGGHMLETALKTVK
YGGCVTTCGNVAGQELQTTVYPFILRGISLLGIDSVQCPVDVRRDVWTLLAKEWGNKELLSYTEECTLEELEKKFALILQ
GKLKGRTVVKI

Sequences:

>Translated_331_residues
MNHTSFRAIVVNEKENHQFVRKVVEREVSSLPEGDVFIQVHYSSLNYKDALSATGNKGVTRTYPHTPGIDAAGVVVSSED
ATIKAGDQVIVTGYDLGMNTSGGFGEYIRVPSSWVVPLPEGMSLKESMMYGTAGFTAALSVYKLIGAGIKPSMGDVLVTG
ATGGVGSVAVSILSKLGFNVVGATGKMEEEDMLLRLGVKKVIHRAELNDESGRPMLKGIYAGVIDTVGGHMLETALKTVK
YGGCVTTCGNVAGQELQTTVYPFILRGISLLGIDSVQCPVDVRRDVWTLLAKEWGNKELLSYTEECTLEELEKKFALILQ
GKLKGRTVVKI
>Mature_331_residues
MNHTSFRAIVVNEKENHQFVRKVVEREVSSLPEGDVFIQVHYSSLNYKDALSATGNKGVTRTYPHTPGIDAAGVVVSSED
ATIKAGDQVIVTGYDLGMNTSGGFGEYIRVPSSWVVPLPEGMSLKESMMYGTAGFTAALSVYKLIGAGIKPSMGDVLVTG
ATGGVGSVAVSILSKLGFNVVGATGKMEEEDMLLRLGVKKVIHRAELNDESGRPMLKGIYAGVIDTVGGHMLETALKTVK
YGGCVTTCGNVAGQELQTTVYPFILRGISLLGIDSVQCPVDVRRDVWTLLAKEWGNKELLSYTEECTLEELEKKFALILQ
GKLKGRTVVKI

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239676, Length=176, Percent_Identity=31.25, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI194239674, Length=176, Percent_Identity=31.25, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI13236495, Length=176, Percent_Identity=31.25, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI1789651, Length=319, Percent_Identity=42.6332288401254, Blast_Score=265, Evalue=3e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR014188 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.1

Molecular weight: Translated: 35552; Mature: 35552

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHTSFRAIVVNEKENHQFVRKVVEREVSSLPEGDVFIQVHYSSLNYKDALSATGNKGVT
CCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHCCCCCCCCE
RTYPHTPGIDAAGVVVSSEDATIKAGDQVIVTGYDLGMNTSGGFGEYIRVPSSWVVPLPE
ECCCCCCCCCCCEEEEECCCCEEECCCEEEEEEEECCCCCCCCCCCEEECCCCEEEECCC
GMSLKESMMYGTAGFTAALSVYKLIGAGIKPSMGDVLVTGATGGVGSVAVSILSKLGFNV
CCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCEE
VGATGKMEEEDMLLRLGVKKVIHRAELNDESGRPMLKGIYAGVIDTVGGHMLETALKTVK
ECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGGCVTTCGNVAGQELQTTVYPFILRGISLLGIDSVQCPVDVRRDVWTLLAKEWGNKELL
CCCHHHHHHHHCCHHHHHHHHHHHHHCHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHH
SYTEECTLEELEKKFALILQGKLKGRTVVKI
HHHHHHHHHHHHHHHHHHEECCCCCCEEEEC
>Mature Secondary Structure
MNHTSFRAIVVNEKENHQFVRKVVEREVSSLPEGDVFIQVHYSSLNYKDALSATGNKGVT
CCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHCCCCCCCCE
RTYPHTPGIDAAGVVVSSEDATIKAGDQVIVTGYDLGMNTSGGFGEYIRVPSSWVVPLPE
ECCCCCCCCCCCEEEEECCCCEEECCCEEEEEEEECCCCCCCCCCCEEECCCCEEEECCC
GMSLKESMMYGTAGFTAALSVYKLIGAGIKPSMGDVLVTGATGGVGSVAVSILSKLGFNV
CCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCEE
VGATGKMEEEDMLLRLGVKKVIHRAELNDESGRPMLKGIYAGVIDTVGGHMLETALKTVK
ECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGGCVTTCGNVAGQELQTTVYPFILRGISLLGIDSVQCPVDVRRDVWTLLAKEWGNKELL
CCCHHHHHHHHCCHHHHHHHHHHHHHCHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHH
SYTEECTLEELEKKFALILQGKLKGRTVVKI
HHHHHHHHHHHHHHHHHHEECCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alcohol; NAD+

Specific reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]