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The map label for this gene is phoP [H]

Identifier: 218235082

GI number: 218235082

Start: 2761554

End: 2762201

Strand: Reverse

Name: phoP [H]

Synonym: BCB4264_A2877

Alternate gene names: 218235082

Gene position: 2762201-2761554 (Counterclockwise)

Preceding gene: 218231240

Following gene: 218233652

Centisome position: 50.97

GC content: 31.33

Gene sequence:

>648_bases
ATGAAAGTTTTAATTGCAGATGACGAACAAGATATGTTAAGGATTTTAAAAGCTTATTTTGAAAAAGAAGGATTTGAAGT
TTTTTTAGCAAAAGACGGGGAGGAAGCACTTCAAATATTTTATGATGAAAAAATTGATTTAGCTATTTTGGATTGGATGA
TGCCAAAACATAGTGGTATTACTGTCTGTCAGGAAATAAAAAAGAATTCAAGCGTAAAAGTATTAATGCTTACGGCGAAA
AGTGAAAGTGAAGATGAATTAGCAGCGCTTCAAAGTGGGGCAGATGAGTACGTGAAAAAACCATTTCATCCAGGAGTACT
AATTACGCGAGCGAAAAAACTTATTCAGCATGATGATATTATTCAAGTACAAGATGTAAAGATAAATTTCGCTAAAAATA
AAGTATATAAAAATGATATAGAGTTAGAAATTACAAAAACAGAGCTCGAATTAATAAAATGCTTTTTAAATCATAAAGGA
ACAATTTTAACTCGTAAAAAATTGCTAGATATTGTCTGGGGATTTGACTATTTTGGAGAAGAGAGAACGGTTGATACACA
TGTAAGAAGGCTACGTAAAAAAATTGGAGAAAATATTATTAAGACGCATCGTGGGCTGGGTTATAGTTTGGAGGAACAAA
GTGAATAA

Upstream 100 bases:

>100_bases
TATCCCCTCAAAAGCTTTAAATATTTTTCTGTCACATTCATGTAACAAAGATGTTGTATGATACAATTGGTTTTTGTTTA
AAAGCAATGGAGGAAAAAAT

Downstream 100 bases:

>100_bases
ACTTGGGAAAAAGCTATTTCTCAGCATTTCTTTAACCGTTATTCTTATATTTACAATTTCTTTATTATTAATTAACTTTC
TCCTGCCGAAATATAATATT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MKVLIADDEQDMLRILKAYFEKEGFEVFLAKDGEEALQIFYDEKIDLAILDWMMPKHSGITVCQEIKKNSSVKVLMLTAK
SESEDELAALQSGADEYVKKPFHPGVLITRAKKLIQHDDIIQVQDVKINFAKNKVYKNDIELEITKTELELIKCFLNHKG
TILTRKKLLDIVWGFDYFGEERTVDTHVRRLRKKIGENIIKTHRGLGYSLEEQSE

Sequences:

>Translated_215_residues
MKVLIADDEQDMLRILKAYFEKEGFEVFLAKDGEEALQIFYDEKIDLAILDWMMPKHSGITVCQEIKKNSSVKVLMLTAK
SESEDELAALQSGADEYVKKPFHPGVLITRAKKLIQHDDIIQVQDVKINFAKNKVYKNDIELEITKTELELIKCFLNHKG
TILTRKKLLDIVWGFDYFGEERTVDTHVRRLRKKIGENIIKTHRGLGYSLEEQSE
>Mature_215_residues
MKVLIADDEQDMLRILKAYFEKEGFEVFLAKDGEEALQIFYDEKIDLAILDWMMPKHSGITVCQEIKKNSSVKVLMLTAK
SESEDELAALQSGADEYVKKPFHPGVLITRAKKLIQHDDIIQVQDVKINFAKNKVYKNDIELEITKTELELIKCFLNHKG
TILTRKKLLDIVWGFDYFGEERTVDTHVRRLRKKIGENIIKTHRGLGYSLEEQSE

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=220, Percent_Identity=33.1818181818182, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=28.4444444444444, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=31.5068493150685, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=33.9366515837104, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=31.0810810810811, Blast_Score=113, Evalue=8e-27,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=27.9816513761468, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1787229, Length=221, Percent_Identity=27.1493212669683, Blast_Score=110, Evalue=5e-26,
Organism=Escherichia coli, GI1788394, Length=222, Percent_Identity=28.3783783783784, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1790863, Length=225, Percent_Identity=29.7777777777778, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=31.1111111111111, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=27.1493212669683, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=29.0178571428571, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI145693140, Length=228, Percent_Identity=25.8771929824561, Blast_Score=87, Evalue=6e-19,
Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=26.4840182648402, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1788550, Length=102, Percent_Identity=37.2549019607843, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=34.1666666666667, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790437, Length=101, Percent_Identity=35.6435643564356, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24916; Mature: 24916

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLIADDEQDMLRILKAYFEKEGFEVFLAKDGEEALQIFYDEKIDLAILDWMMPKHSGI
CEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCEEEEHHHCCCCCCH
TVCQEIKKNSSVKVLMLTAKSESEDELAALQSGADEYVKKPFHPGVLITRAKKLIQHDDI
HHHHHHHCCCCEEEEEEEECCCCHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHCCCCC
IQVQDVKINFAKNKVYKNDIELEITKTELELIKCFLNHKGTILTRKKLLDIVWGFDYFGE
EEEEEEEEEEECCCEECCCCEEEEEHHHHHHHHHHHCCCCCEEHHHHHHHHHHCHHHCCC
ERTVDTHVRRLRKKIGENIIKTHRGLGYSLEEQSE
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKVLIADDEQDMLRILKAYFEKEGFEVFLAKDGEEALQIFYDEKIDLAILDWMMPKHSGI
CEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCEEEEHHHCCCCCCH
TVCQEIKKNSSVKVLMLTAKSESEDELAALQSGADEYVKKPFHPGVLITRAKKLIQHDDI
HHHHHHHCCCCEEEEEEEECCCCHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHCCCCC
IQVQDVKINFAKNKVYKNDIELEITKTELELIKCFLNHKGTILTRKKLLDIVWGFDYFGE
EEEEEEEEEEECCCEECCCCEEEEEHHHHHHHHHHHCCCCCEEHHHHHHHHHHCHHHCCC
ERTVDTHVRRLRKKIGENIIKTHRGLGYSLEEQSE
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]