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The map label for this gene is ndhF [H]

Identifier: 218234779

GI number: 218234779

Start: 3060727

End: 3062259

Strand: Reverse

Name: ndhF [H]

Synonym: BCB4264_A3176

Alternate gene names: 218234779

Gene position: 3062259-3060727 (Counterclockwise)

Preceding gene: 218233886

Following gene: 218232373

Centisome position: 56.51

GC content: 35.75

Gene sequence:

>1533_bases
ATGTTAATTTCGCTGAGTTCATCAACACTGTTAACTTTATTTTTTATGGCGCTTAGTGCTTCTTGGCTAAGTGGATTATT
ATTTTTAAATGCAAGGATACCTTTACGTTTTGTTCATATCCATATTGGTATCGCTGCTTTACCTTCATTGGTTTCTTTAC
TCGCACTTGTTAATAACAATGGAGATAGAGTTGTGGGGCCTTGGCATCTAGATACTTTAGCTTGGTTAATGGCTTTCTTT
GTTCTTACAATTGGTTTAATCATTCAGCGTTTCTCTGTACGTTATTTAATGGGAGATCGCTCATATCGAAAATACTTTGC
ACTTTTTACATGTACTACAGGTGTATCTTCGGTTGCATGGTTAAGTGATGATCTTCGCTTAATGCTCATTTGTTGGGGAG
CAACGCTTATAGGATTGGTTCTACTTATAGGGCTAAATAAAGGGTGGAAAGTAGTTAGTGAAGCAACTAAAATCTCTGGC
TACCTATTTACAATAAGTTGGATTGCCTTACTATCAGCTATCATTTGGCTGTTTCAAATAACTGGACAGTGGCAGTTAAC
ATCAGTTTTAACGAATGAAAATGTAGTGCTACATGGAACATTGGAGAGAACAGGAATTAACTTATTAATTATATTAGCGG
TGATGATTCCAGCAGCACAATGGCCTTTTCAAAGATGGTTAATTGAGTCTGCTGTTGCTCCAACTCCTGTTTCTGCTATT
ATGCATGCGGGTTTAGTAAATGCTGGCGGTATCATGTTAACTAGATTTTCACCTCTTTTTCATGATGATATTGCACAAAT
CATTTTACTAATTTTCTCTAGTATTTCTATCTTAATAGGTACAGGAATTAGTTTAGTCCAAGTTGATTATAAACGTCAGC
TAGTAGGTTCAACTATTGCACAAATGGGATTTATGCTTATTCAATGTGCATTAGGCGCCTATTTAGCAGCTATTATTCAT
TTAATTTTACATGGTTTGTTTAAAGCTACACTATTTTTACAAGCTGGTTCTTCCGTGCAACGTTTTGGGGTAGTGAATCA
GTCTAATGAAAAGATGTCCAATTTATGGATTATAGTTGGGCGTGTTTTAGGATTATTTATAGCAATTACTTTCTGGTTTA
TGACTTCTGGAGAGGGGTATCAACTAGTTAGTGCGTTAATCTTAGGCTGGTCACTATACTTTTCATGGAAACAGCTTGTT
GTTTTTGGAGAGGGAAGAATGGGACGAATTGCTGGCGTAATTGTTTTGATTGGATTTTCTCTCATTTACTTTACCGTTCA
TAATTCTCTTTATAAATGGTTGCATACTGATATTTATCAAAGTGTTCAACCTTCAGCTCCAGCCGTTATCTTTGTTATAT
GTATTTTACTATTTAGTAGTGTTATTAGTACTTTCGTTACTCGTCATCAATCTTCTACTTTATTCGCTGTACTTTATCTT
TGGTTAGTTCGAGTAGGTGAGGCGAGACGAAAGTCAGTAGAAAGTCACCCAAGCTATCTGAAACATTATGTATCAAAGGG
AGGTAATTCGTGA

Upstream 100 bases:

>100_bases
ACGATGTACTAAAAGAGTGAATGAAAATTGAAATTAAAAAAACTATCGTAATGAAAAGAAATTTTTATAGGCTATTTTCG
CTTAGAAGGGAGTATTTAAC

Downstream 100 bases:

>100_bases
TGAGCATACCGTCAATATTAAAGAAAGATACAAACATTGATATGCAAGAAAATAATATAAATGATTTAGTTGCATCTGCT
AGCCGAGTTATTGCGCCACT

Product: NADH dehydrogenase subunit 5

Products: NA

Alternate protein names: NADH dehydrogenase subunit 5 [H]

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MLISLSSSTLLTLFFMALSASWLSGLLFLNARIPLRFVHIHIGIAALPSLVSLLALVNNNGDRVVGPWHLDTLAWLMAFF
VLTIGLIIQRFSVRYLMGDRSYRKYFALFTCTTGVSSVAWLSDDLRLMLICWGATLIGLVLLIGLNKGWKVVSEATKISG
YLFTISWIALLSAIIWLFQITGQWQLTSVLTNENVVLHGTLERTGINLLIILAVMIPAAQWPFQRWLIESAVAPTPVSAI
MHAGLVNAGGIMLTRFSPLFHDDIAQIILLIFSSISILIGTGISLVQVDYKRQLVGSTIAQMGFMLIQCALGAYLAAIIH
LILHGLFKATLFLQAGSSVQRFGVVNQSNEKMSNLWIIVGRVLGLFIAITFWFMTSGEGYQLVSALILGWSLYFSWKQLV
VFGEGRMGRIAGVIVLIGFSLIYFTVHNSLYKWLHTDIYQSVQPSAPAVIFVICILLFSSVISTFVTRHQSSTLFAVLYL
WLVRVGEARRKSVESHPSYLKHYVSKGGNS

Sequences:

>Translated_510_residues
MLISLSSSTLLTLFFMALSASWLSGLLFLNARIPLRFVHIHIGIAALPSLVSLLALVNNNGDRVVGPWHLDTLAWLMAFF
VLTIGLIIQRFSVRYLMGDRSYRKYFALFTCTTGVSSVAWLSDDLRLMLICWGATLIGLVLLIGLNKGWKVVSEATKISG
YLFTISWIALLSAIIWLFQITGQWQLTSVLTNENVVLHGTLERTGINLLIILAVMIPAAQWPFQRWLIESAVAPTPVSAI
MHAGLVNAGGIMLTRFSPLFHDDIAQIILLIFSSISILIGTGISLVQVDYKRQLVGSTIAQMGFMLIQCALGAYLAAIIH
LILHGLFKATLFLQAGSSVQRFGVVNQSNEKMSNLWIIVGRVLGLFIAITFWFMTSGEGYQLVSALILGWSLYFSWKQLV
VFGEGRMGRIAGVIVLIGFSLIYFTVHNSLYKWLHTDIYQSVQPSAPAVIFVICILLFSSVISTFVTRHQSSTLFAVLYL
WLVRVGEARRKSVESHPSYLKHYVSKGGNS
>Mature_510_residues
MLISLSSSTLLTLFFMALSASWLSGLLFLNARIPLRFVHIHIGIAALPSLVSLLALVNNNGDRVVGPWHLDTLAWLMAFF
VLTIGLIIQRFSVRYLMGDRSYRKYFALFTCTTGVSSVAWLSDDLRLMLICWGATLIGLVLLIGLNKGWKVVSEATKISG
YLFTISWIALLSAIIWLFQITGQWQLTSVLTNENVVLHGTLERTGINLLIILAVMIPAAQWPFQRWLIESAVAPTPVSAI
MHAGLVNAGGIMLTRFSPLFHDDIAQIILLIFSSISILIGTGISLVQVDYKRQLVGSTIAQMGFMLIQCALGAYLAAIIH
LILHGLFKATLFLQAGSSVQRFGVVNQSNEKMSNLWIIVGRVLGLFIAITFWFMTSGEGYQLVSALILGWSLYFSWKQLV
VFGEGRMGRIAGVIVLIGFSLIYFTVHNSLYKWLHTDIYQSVQPSAPAVIFVICILLFSSVISTFVTRHQSSTLFAVLYL
WLVRVGEARRKSVESHPSYLKHYVSKGGNS

Specific function: Ndh-1 Shuttles Electrons From NADH, Via Fmn And Iron- Sulfur (Fe-S) Centers, To Quinones In The Respiratory Chain. The Immediate Electron Acceptor For The Enzyme In This Species Is Believed To Be Ubiquinone. Couples The Redox Reaction To Proton Translocat

COG id: COG1009

COG function: function code CP; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 5 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=136, Percent_Identity=33.0882352941176, Blast_Score=73, Evalue=7e-13,
Organism=Escherichia coli, GI1788614, Length=280, Percent_Identity=30, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788613, Length=253, Percent_Identity=27.6679841897233, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788831, Length=134, Percent_Identity=31.3432835820896, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1788829, Length=304, Percent_Identity=27.9605263157895, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR001516 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF00662 Oxidored_q1_N [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 56570; Mature: 56570

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLISLSSSTLLTLFFMALSASWLSGLLFLNARIPLRFVHIHIGIAALPSLVSLLALVNNN
CEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCC
GDRVVGPWHLDTLAWLMAFFVLTIGLIIQRFSVRYLMGDRSYRKYFALFTCTTGVSSVAW
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHEEECCCCHHHHH
LSDDLRLMLICWGATLIGLVLLIGLNKGWKVVSEATKISGYLFTISWIALLSAIIWLFQI
HCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGQWQLTSVLTNENVVLHGTLERTGINLLIILAVMIPAAQWPFQRWLIESAVAPTPVSAI
CCCEEEEEEECCCCEEEEECHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHH
MHAGLVNAGGIMLTRFSPLFHDDIAQIILLIFSSISILIGTGISLVQVDYKRQLVGSTIA
HHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHH
QMGFMLIQCALGAYLAAIIHLILHGLFKATLFLQAGSSVQRFGVVNQSNEKMSNLWIIVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHH
RVLGLFIAITFWFMTSGEGYQLVSALILGWSLYFSWKQLVVFGEGRMGRIAGVIVLIGFS
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHH
LIYFTVHNSLYKWLHTDIYQSVQPSAPAVIFVICILLFSSVISTFVTRHQSSTLFAVLYL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
WLVRVGEARRKSVESHPSYLKHYVSKGGNS
HHHHHCHHHHHHHHCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MLISLSSSTLLTLFFMALSASWLSGLLFLNARIPLRFVHIHIGIAALPSLVSLLALVNNN
CEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCC
GDRVVGPWHLDTLAWLMAFFVLTIGLIIQRFSVRYLMGDRSYRKYFALFTCTTGVSSVAW
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHEEECCCCHHHHH
LSDDLRLMLICWGATLIGLVLLIGLNKGWKVVSEATKISGYLFTISWIALLSAIIWLFQI
HCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGQWQLTSVLTNENVVLHGTLERTGINLLIILAVMIPAAQWPFQRWLIESAVAPTPVSAI
CCCEEEEEEECCCCEEEEECHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHH
MHAGLVNAGGIMLTRFSPLFHDDIAQIILLIFSSISILIGTGISLVQVDYKRQLVGSTIA
HHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHH
QMGFMLIQCALGAYLAAIIHLILHGLFKATLFLQAGSSVQRFGVVNQSNEKMSNLWIIVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHH
RVLGLFIAITFWFMTSGEGYQLVSALILGWSLYFSWKQLVVFGEGRMGRIAGVIVLIGFS
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHH
LIYFTVHNSLYKWLHTDIYQSVQPSAPAVIFVICILLFSSVISTFVTRHQSSTLFAVLYL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
WLVRVGEARRKSVESHPSYLKHYVSKGGNS
HHHHHCHHHHHHHHCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]