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The map label for this gene is phnW [H]

Identifier: 218234728

GI number: 218234728

Start: 1335098

End: 1336195

Strand: Direct

Name: phnW [H]

Synonym: BCB4264_A1378

Alternate gene names: 218234728

Gene position: 1335098-1336195 (Clockwise)

Preceding gene: 218233697

Following gene: 218234104

Centisome position: 24.64

GC content: 35.88

Gene sequence:

>1098_bases
ATGAATGAAAATCACTACTTATTATTAACACCAGGACCATTAACGACAACAAAATCAGTAAAAGAAGTTATGCTATACGA
TTGGTGTACGTGGGATGATGAATATAATACGATGGTGCAAGAAGTAAGAGCTAAACTTGTATCGTTAGCGACGAAGGAAG
AAGAGAAATATACAACAGTGTTAATGCAAGGAAGCGGTACGTTTTCAGTTGAAGCAGTAATTGGTTCTGTTATTCCGGCA
AATGGGAAGCTTCTCGTTTGTACAAATGGTGCGTACGGTAAGCGAATTGTGCAAATGGCAGAGATGTTACAGATTGATGT
AGTGATCAGTCAAACAGAAGAGTGGGAACCTACTAATATTGTAGAAGTAGAAAAGTTATTGCAAGAAGATAAAGAGATTA
CGCATATTGCAGTTGTTCATTGTGAAACAACGACAGGAATTATAAATCCAATTGTAGATGTATGTAAATTAGGACAACAG
TATGGAAAGGTTACAATTGTTGATGCGATGAGTAGTTTCGGCGGGATTGAAATAGACATTGCTGATTTACAAATTGATTT
TTTAATTAGTAGTGCAAATAAGTGTATTCAAGGGGTTCCTGGATTCGGATTTGTAATCGCAAAACGTGATGAATTATTGA
AGTGTAAAGGGCAAGGACGCTCTTTATCTCTTGATTTATATGATCAGTGGGAAACGATGGAAAAACAAAATGGGAAATGG
CGTTTTACTTCGCCTACACATGTTGTACATGCTTTTTATCAAGCGCTACTTGAGCTAGAAAAAGAAGGTGGAGTAAGAGC
GCGTTACAATCGATATTACAACAATCAAAAACTACTAGTGAATAGAATGGGAGAAATCGGATTTAAGCCACTAGTAGATA
AGAAATATCAATCTCCTATTATTACATCTTTCATTTATCCAAAAGAGGGGTTTGAGTTTCAACAGTTATATAACGAATTA
AAGCGTTATGGATTTGTTATTTACCCTGGGAAAATTTCGAAAGTAGATACGTTCCGCATTGGAAATATCGGTGATGTACA
TGAAGAAGATATTAATCGCTTAGTTGATTGTATGGCTAAAGGAGCTGTTATTGGGTGA

Upstream 100 bases:

>100_bases
TGGGGCTCATTTTACGATTGAAACGATGCAGGAGCTCGAAAACGTAATGGAACATATCGAGAAACAAGAACTTATTATTT
CATAAAAGGGGCACGGGATC

Downstream 100 bases:

>100_bases
AAGTATTTTGCTTAGGTGGAGCAGGTAAAATTTGTCGTGAAGCTATTTTGGATTTAGTTCAATTTTCATCTTTTGAGACG
ATTACTGTAGCCGATTTTAA

Product: 2-aminoethylphosphonate--pyruvate transaminase

Products: NA

Alternate protein names: 2-aminoethylphosphonate aminotransferase; AEP transaminase; AEPT [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MNENHYLLLTPGPLTTTKSVKEVMLYDWCTWDDEYNTMVQEVRAKLVSLATKEEEKYTTVLMQGSGTFSVEAVIGSVIPA
NGKLLVCTNGAYGKRIVQMAEMLQIDVVISQTEEWEPTNIVEVEKLLQEDKEITHIAVVHCETTTGIINPIVDVCKLGQQ
YGKVTIVDAMSSFGGIEIDIADLQIDFLISSANKCIQGVPGFGFVIAKRDELLKCKGQGRSLSLDLYDQWETMEKQNGKW
RFTSPTHVVHAFYQALLELEKEGGVRARYNRYYNNQKLLVNRMGEIGFKPLVDKKYQSPIITSFIYPKEGFEFQQLYNEL
KRYGFVIYPGKISKVDTFRIGNIGDVHEEDINRLVDCMAKGAVIG

Sequences:

>Translated_365_residues
MNENHYLLLTPGPLTTTKSVKEVMLYDWCTWDDEYNTMVQEVRAKLVSLATKEEEKYTTVLMQGSGTFSVEAVIGSVIPA
NGKLLVCTNGAYGKRIVQMAEMLQIDVVISQTEEWEPTNIVEVEKLLQEDKEITHIAVVHCETTTGIINPIVDVCKLGQQ
YGKVTIVDAMSSFGGIEIDIADLQIDFLISSANKCIQGVPGFGFVIAKRDELLKCKGQGRSLSLDLYDQWETMEKQNGKW
RFTSPTHVVHAFYQALLELEKEGGVRARYNRYYNNQKLLVNRMGEIGFKPLVDKKYQSPIITSFIYPKEGFEFQQLYNEL
KRYGFVIYPGKISKVDTFRIGNIGDVHEEDINRLVDCMAKGAVIG
>Mature_365_residues
MNENHYLLLTPGPLTTTKSVKEVMLYDWCTWDDEYNTMVQEVRAKLVSLATKEEEKYTTVLMQGSGTFSVEAVIGSVIPA
NGKLLVCTNGAYGKRIVQMAEMLQIDVVISQTEEWEPTNIVEVEKLLQEDKEITHIAVVHCETTTGIINPIVDVCKLGQQ
YGKVTIVDAMSSFGGIEIDIADLQIDFLISSANKCIQGVPGFGFVIAKRDELLKCKGQGRSLSLDLYDQWETMEKQNGKW
RFTSPTHVVHAFYQALLELEKEGGVRARYNRYYNNQKLLVNRMGEIGFKPLVDKKYQSPIITSFIYPKEGFEFQQLYNEL
KRYGFVIYPGKISKVDTFRIGNIGDVHEEDINRLVDCMAKGAVIG

Specific function: Involved in phosphonate degradation [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=310, Percent_Identity=22.9032258064516, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17536281, Length=362, Percent_Identity=22.3756906077348, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017688
- InterPro:   IPR000192
- InterPro:   IPR012703
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.37 [H]

Molecular weight: Translated: 41269; Mature: 41269

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNENHYLLLTPGPLTTTKSVKEVMLYDWCTWDDEYNTMVQEVRAKLVSLATKEEEKYTTV
CCCCCEEEEECCCCCCHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEE
LMQGSGTFSVEAVIGSVIPANGKLLVCTNGAYGKRIVQMAEMLQIDVVISQTEEWEPTNI
EEECCCCEEHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHEEEEEECCCCCCCCCH
VEVEKLLQEDKEITHIAVVHCETTTGIINPIVDVCKLGQQYGKVTIVDAMSSFGGIEIDI
HHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCEEEEE
ADLQIDFLISSANKCIQGVPGFGFVIAKRDELLKCKGQGRSLSLDLYDQWETMEKQNGKW
EEEEEEEEHHHHHHHHHCCCCCEEEEECCCCCEEECCCCCEEEEEHHHHHHHHHHCCCCE
RFTSPTHVVHAFYQALLELEKEGGVRARYNRYYNNQKLLVNRMGEIGFKPLVDKKYQSPI
EECCHHHHHHHHHHHHHHHHHCCCCEEEHHHHCCCCHHEEHHHHCCCCCCCCCCCCCCCC
ITSFIYPKEGFEFQQLYNELKRYGFVIYPGKISKVDTFRIGNIGDVHEEDINRLVDCMAK
CEEEECCCCCCCHHHHHHHHHHCEEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHC
GAVIG
CCCCC
>Mature Secondary Structure
MNENHYLLLTPGPLTTTKSVKEVMLYDWCTWDDEYNTMVQEVRAKLVSLATKEEEKYTTV
CCCCCEEEEECCCCCCHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEE
LMQGSGTFSVEAVIGSVIPANGKLLVCTNGAYGKRIVQMAEMLQIDVVISQTEEWEPTNI
EEECCCCEEHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHEEEEEECCCCCCCCCH
VEVEKLLQEDKEITHIAVVHCETTTGIINPIVDVCKLGQQYGKVTIVDAMSSFGGIEIDI
HHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCEEEEE
ADLQIDFLISSANKCIQGVPGFGFVIAKRDELLKCKGQGRSLSLDLYDQWETMEKQNGKW
EEEEEEEEHHHHHHHHHCCCCCEEEEECCCCCEEECCCCCEEEEEHHHHHHHHHHCCCCE
RFTSPTHVVHAFYQALLELEKEGGVRARYNRYYNNQKLLVNRMGEIGFKPLVDKKYQSPI
EECCHHHHHHHHHHHHHHHHHCCCCEEEHHHHCCCCHHEEHHHHCCCCCCCCCCCCCCCC
ITSFIYPKEGFEFQQLYNELKRYGFVIYPGKISKVDTFRIGNIGDVHEEDINRLVDCMAK
CEEEECCCCCCCHHHHHHHHHHCEEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHC
GAVIG
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA