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The map label for this gene is ycaK [C]

Identifier: 218234693

GI number: 218234693

Start: 3192075

End: 3192650

Strand: Reverse

Name: ycaK [C]

Synonym: BCB4264_A3310

Alternate gene names: 218234693

Gene position: 3192650-3192075 (Counterclockwise)

Preceding gene: 218233823

Following gene: 218235030

Centisome position: 58.92

GC content: 36.81

Gene sequence:

>576_bases
GTGAACGTACTAATTATATATGCCCATCCTAACCCTTCAAGTTTTAACGCGGCAATTTTCAATCATGTGCAAAAAGGACT
ACAGGAAACAAATCATTCAGTTACCGTACTTGATTTATACAAAGAACAATTTGATCCAGTCCTCGTATTTAATGAAGAGA
AGAAAAGACGCGATTTAGTAAATGAAGAGGAAACAGCTCGGTATAGAACGTTAGTAGAAGAAGCAGATACACTTTTATTC
ATCTATCCAATATGGTGGTGGGGGATGCCAGCAATTTTAAAAGGTTTTATTGATCGTATTTTCGTAGCTGGATTTGCTTA
TAAATATGAAGGGGCTCTGCCGAAAGGATTATTGCAAGGGAAAAAAGCGTGGGTTATTAATACGTTAGACTCGCCTCTAT
GGTACGTCGCATTGTTATATCGATCAGTAGATTGGATTATAATGAAGAGAGGTGTTTTACGTTTTTGTGGCATTCGCGAT
ATAAAACGGTCAGTGTTTCAATCTGTGAAAACGAGTAAAGTATCAAAGCGTGAGAAATGGTTATTACAAATAGAAGAAAA
GGCTCGTGCATTATGA

Upstream 100 bases:

>100_bases
TATTATTAAATCGATTGTTGCAAAGTTCGAAAAACGTACAAATTGTAGAGAAGTTATTAAAGAAGGGGAAACTTTAACGT
ATAGAGGGAGTTGTTTTGTA

Downstream 100 bases:

>100_bases
ATGAAGTCGATCGTATTATAAACTGTGTTCAGTATGATGGCGAACTTTTTCGGAAGTATGTTACATGTTTACTTCAATTG
AAAAAATGTAGCGAAACATT

Product: NAD(P)H dehydrogenase, quinone family

Products: NAD+; NADP+; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MNVLIIYAHPNPSSFNAAIFNHVQKGLQETNHSVTVLDLYKEQFDPVLVFNEEKKRRDLVNEEETARYRTLVEEADTLLF
IYPIWWWGMPAILKGFIDRIFVAGFAYKYEGALPKGLLQGKKAWVINTLDSPLWYVALLYRSVDWIIMKRGVLRFCGIRD
IKRSVFQSVKTSKVSKREKWLLQIEEKARAL

Sequences:

>Translated_191_residues
MNVLIIYAHPNPSSFNAAIFNHVQKGLQETNHSVTVLDLYKEQFDPVLVFNEEKKRRDLVNEEETARYRTLVEEADTLLF
IYPIWWWGMPAILKGFIDRIFVAGFAYKYEGALPKGLLQGKKAWVINTLDSPLWYVALLYRSVDWIIMKRGVLRFCGIRD
IKRSVFQSVKTSKVSKREKWLLQIEEKARAL
>Mature_191_residues
MNVLIIYAHPNPSSFNAAIFNHVQKGLQETNHSVTVLDLYKEQFDPVLVFNEEKKRRDLVNEEETARYRTLVEEADTLLF
IYPIWWWGMPAILKGFIDRIFVAGFAYKYEGALPKGLLQGKKAWVINTLDSPLWYVALLYRSVDWIIMKRGVLRFCGIRD
IKRSVFQSVKTSKVSKREKWLLQIEEKARAL

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD(P)H dehydrogenase (quinone) family [H]

Homologues:

Organism=Homo sapiens, GI156564357, Length=181, Percent_Identity=34.2541436464088, Blast_Score=88, Evalue=5e-18,
Organism=Homo sapiens, GI4505415, Length=214, Percent_Identity=27.5700934579439, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1787129, Length=114, Percent_Identity=35.0877192982456, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: 1.6.99.2

Molecular weight: Translated: 22368; Mature: 22368

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLIIYAHPNPSSFNAAIFNHVQKGLQETNHSVTVLDLYKEQFDPVLVFNEEKKRRDLV
CCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEHHHHCCCEEEECCCHHHHHCC
NEEETARYRTLVEEADTLLFIYPIWWWGMPAILKGFIDRIFVAGFAYKYEGALPKGLLQG
CCHHHHHHHHHHHHCCCEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCC
KKAWVINTLDSPLWYVALLYRSVDWIIMKRGVLRFCGIRDIKRSVFQSVKTSKVSKREKW
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
LLQIEEKARAL
HHHHHHHHCCC
>Mature Secondary Structure
MNVLIIYAHPNPSSFNAAIFNHVQKGLQETNHSVTVLDLYKEQFDPVLVFNEEKKRRDLV
CCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEHHHHCCCEEEECCCHHHHHCC
NEEETARYRTLVEEADTLLFIYPIWWWGMPAILKGFIDRIFVAGFAYKYEGALPKGLLQG
CCHHHHHHHHHHHHCCCEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCC
KKAWVINTLDSPLWYVALLYRSVDWIIMKRGVLRFCGIRDIKRSVFQSVKTSKVSKREKW
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
LLQIEEKARAL
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; NADPH; H+; acceptor

Specific reaction: NAD(P)H + H+ + acceptor = NAD(P)+ + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]