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The map label for this gene is resA [H]

Identifier: 218234648

GI number: 218234648

Start: 1462698

End: 1463219

Strand: Direct

Name: resA [H]

Synonym: BCB4264_A1528

Alternate gene names: 218234648

Gene position: 1462698-1463219 (Clockwise)

Preceding gene: 218232708

Following gene: 218233704

Centisome position: 26.99

GC content: 32.76

Gene sequence:

>522_bases
ATGAAGAAAAATCGTTTATTATTTCGCGTTATTATTCTACTCATTTTATGTGGTGCTGTAGGATTTACCCTTTATCAAGG
ATTCTTTGCTAATAAAGAGAAAATGCAAATCGGAAAAGAAGCACCTAACTTTATTGTGACGGATTTAGAAGGAAAGAAAA
TTGAACTAAAAGATTTAAAGGGAAAAGGTGTATTTTTAAACTTTTGGGGCACGTGGTGTAAACCTTGTGAAAAAGAAATG
CCTTATATGAATGAATTATATCCAAAGTATAAAGAAAAAGGCGTTGAAATCATAGCGTTAGATGCAGATGAAACGGATAT
TGCAGTAAAGAACTTTGTGAACCAATATGGTTTGAAATTCCCAGTTGCCATTGATAAAGGACAAAAGATTATAGGAACAT
ATGGAGTAGGTCCTTTACCGACAAGCTTTTTGATTGATAAAGATGGAAAAGTAGTGGAGCAAATTATAGGGGAACAAACG
AAAGAACAGTTAGAAGGGTATTTAAAGAAAATTACTCCGTAA

Upstream 100 bases:

>100_bases
GAGTTAAAAATTCACCAGTGGAGTGCTCTGCTGGTGATTTATTCAATACAACATTTACAGAAGATAATACATAACATTTA
CCGAGGAGAGGAGAGGTAAT

Downstream 100 bases:

>100_bases
TAAAGAAAGCCTTTACATAAGGGGTGCGTGTTTATAGTGCCTCTGGTTTAAAAATTCTGAGTATTGCGGTAACTTGAGGT
TAGAATATACAATAGTACAT

Product: thiol-disulfide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MKKNRLLFRVIILLILCGAVGFTLYQGFFANKEKMQIGKEAPNFIVTDLEGKKIELKDLKGKGVFLNFWGTWCKPCEKEM
PYMNELYPKYKEKGVEIIALDADETDIAVKNFVNQYGLKFPVAIDKGQKIIGTYGVGPLPTSFLIDKDGKVVEQIIGEQT
KEQLEGYLKKITP

Sequences:

>Translated_173_residues
MKKNRLLFRVIILLILCGAVGFTLYQGFFANKEKMQIGKEAPNFIVTDLEGKKIELKDLKGKGVFLNFWGTWCKPCEKEM
PYMNELYPKYKEKGVEIIALDADETDIAVKNFVNQYGLKFPVAIDKGQKIIGTYGVGPLPTSFLIDKDGKVVEQIIGEQT
KEQLEGYLKKITP
>Mature_173_residues
MKKNRLLFRVIILLILCGAVGFTLYQGFFANKEKMQIGKEAPNFIVTDLEGKKIELKDLKGKGVFLNFWGTWCKPCEKEM
PYMNELYPKYKEKGVEIIALDADETDIAVKNFVNQYGLKFPVAIDKGQKIIGTYGVGPLPTSFLIDKDGKVVEQIIGEQT
KEQLEGYLKKITP

Specific function: Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalent

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane (By similarity) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=179, Percent_Identity=26.8156424581006, Blast_Score=64, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: NA

Molecular weight: Translated: 19616; Mature: 19616

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNRLLFRVIILLILCGAVGFTLYQGFFANKEKMQIGKEAPNFIVTDLEGKKIELKDLK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCEEEECCCCCEEEEEECC
GKGVFLNFWGTWCKPCEKEMPYMNELYPKYKEKGVEIIALDADETDIAVKNFVNQYGLKF
CCEEEEECCCCCCCCHHHCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCC
PVAIDKGQKIIGTYGVGPLPTSFLIDKDGKVVEQIIGEQTKEQLEGYLKKITP
CEEECCCCEEEEECCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKNRLLFRVIILLILCGAVGFTLYQGFFANKEKMQIGKEAPNFIVTDLEGKKIELKDLK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCEEEECCCCCEEEEEECC
GKGVFLNFWGTWCKPCEKEMPYMNELYPKYKEKGVEIIALDADETDIAVKNFVNQYGLKF
CCEEEEECCCCCCCCHHHCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCC
PVAIDKGQKIIGTYGVGPLPTSFLIDKDGKVVEQIIGEQTKEQLEGYLKKITP
CEEECCCCEEEEECCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA