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The map label for this gene is ykoW [H]

Identifier: 218234545

GI number: 218234545

Start: 555314

End: 557383

Strand: Direct

Name: ykoW [H]

Synonym: BCB4264_A0585

Alternate gene names: 218234545

Gene position: 555314-557383 (Clockwise)

Preceding gene: 218234183

Following gene: 218233968

Centisome position: 10.25

GC content: 29.61

Gene sequence:

>2070_bases
ATGAAGGAAGAATATAGTCATCAAAATACCTTTTTAAGTATGATAGATATGGATTTAATTAGACAAGGATTATTACATGC
TATTCAAGATTTAGTATTCATATTGAAAGTTATTGATAATGAAACGTTTCAATATATGTATGTGAATAAAATAGGAATGG
ATTATGCTAGGTTAAGCGAAGAGTGCTATGGAAAAACTTTTGCAGAAGTATTACCAAAAGATATAGCGGGGATATTGCAA
AGGCAATATGCAAAAGTAGTGAGAGAAGCGAAAGCACACACCTTTTGTGATGTAGTCAATTTACCAAAAGGTGAGATACA
TTATGAATCTTCACTTAATCCTGTATGCGATGAAGAAGGAATATGTCAATTTGTTATTTGTATTACAAGAGATATTACAG
CTCAAATTGAGGAGAAGACAAAGATAGAGGAAAAACAAATGTTATTTAAGTCGTTACTGGAATATAATAATGACTCAATT
ATATCTATAGATTCTATAGGGAGAGTTACATATGCAAATCCGGCAACGTATGAAATATTTGGATACCGGTATGAGGAATT
AAATAATAAATTTATTTTTGAATTCATTAATAAAGAATATGAAAAAGATTTTCAAATTATATTTAAGGGATCGATGCAAG
GAAAAGCAAAACAAATTGTTTCAAAGAAATATGTTCATAAAGAAGGGTACGAGCTATATATTTCTTTGAGAACTATCCCG
ATTATTGTGAACGGTGAAATTGTTGGGATTTATATTGTTACGAGAGATGTTACAAGGCAAGTATTAAACGAAATGCGAAC
AGAATATTTAGCTTACTATGACCAGTTAACGGGATTAATGAATAGAATTTCATGTACAAATAAGTTAAATACTTTTTTAA
ATGAGAGTGTAAATTTTGCACTTGTATTTATAGATTTAGATGAGTTTCATCGTATTAATGATACATTTGGTCATAAAGAG
GGAGATAAAGTATTACAAAAAGTTACAGAATGTTTAAGCAATCTAAAAATAGAAGATATGCACTTATTTAGAGAACACGA
TGATCAATTTGTTATGTTGATAGAAAATATAACGAAAGAATATGTAGAGGAAGTTGCAAAAAGCATACTGAAAAATATTA
GTGAATATTTTGTAATCGAAGAAGAAGATGTATATTTAAGTGCATCAATTGGAATTGTAATGGCTCCAGCAGATGGAGAA
GATGAAAAAATACTATTTCAGAGGGTCGATGCTGCTTTAGAAAAAGCAAAAGAAAAAGGAAAAGGACATTATCATTTTTA
TTGTAGTGGATTAGACTGTGAGCGTGAACAAAGGTTTATAATAGAAAACCAGTTACATCGTGCTATAGAAAAAAATGAAT
TTTTCTTATATTATCAGCCACAAATTAATATTGAAACGAAAAAAATAGCTAGTATGGAAGCTTTAATAAGGTGGGAGAAT
AAGGAATTAGGATTTGTTTCTCCGAACCAATTTATTCCATTGGCGGAAAGAACAGGATTTATTATTAAGCTCGATGAATG
GGTAGTAAATCAAGTGTGTCAGCAACTGCGCGAATGGTTAAATAAAGGATATGAAGTGGTCCCAATTGCGGTTAATATTT
CAGCTAGACACTTTCGTTCTATTACATTAATAGAGATGATTACACGGGCTTTAAATAAGTACAATGTATCAGCTCATTTA
TTAGCGATAGAGGTTACAGAAGGAGCTCTTATACATAAAGATATATCAAAGAGAGTGTTACTACAATTAAAAGAACAAAA
TTTAAAGATTCATTTAGATGATTTTGGAACAGGCTATTCATCTTTAAGTTATTTAAAAACATATCCAATTGATACTTTAA
AAATTGATCGTTCTTTTATGGAAGGTATACATATAGATGAACGTGATACGAATATTACAGCTGCAATTATTCATTTAGCT
CATACTTTAGAATTGAATATAATTGCAGAAGGAGTAGAAAAAAAGGAGCAAATACAGTTTTTGAAAGAAAAGAATGTGAA
GCTTGTACAAGGTTATTATTATAGCCGACCACTATCCAAATATGATATGGAAAATATGTATTATAAATAA

Upstream 100 bases:

>100_bases
TAAAATAAAAATAATATATAATCATACATTTAAAAGAGAGGACATAATCATATAGAATGGGATATATGATTAAAAATAGA
TAAGACGGGTTGAGATAAAT

Downstream 100 bases:

>100_bases
AAAAATGATGTGCTAAAAGCACATCATTTTTTATGTGTACCTGGTTTGTCATTGTAACCGGATGTAAAAATAGCTGTAAG
AAATGTGAGTGATACACCTA

Product: sensory box/GGDEF family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 689; Mature: 689

Protein sequence:

>689_residues
MKEEYSHQNTFLSMIDMDLIRQGLLHAIQDLVFILKVIDNETFQYMYVNKIGMDYARLSEECYGKTFAEVLPKDIAGILQ
RQYAKVVREAKAHTFCDVVNLPKGEIHYESSLNPVCDEEGICQFVICITRDITAQIEEKTKIEEKQMLFKSLLEYNNDSI
ISIDSIGRVTYANPATYEIFGYRYEELNNKFIFEFINKEYEKDFQIIFKGSMQGKAKQIVSKKYVHKEGYELYISLRTIP
IIVNGEIVGIYIVTRDVTRQVLNEMRTEYLAYYDQLTGLMNRISCTNKLNTFLNESVNFALVFIDLDEFHRINDTFGHKE
GDKVLQKVTECLSNLKIEDMHLFREHDDQFVMLIENITKEYVEEVAKSILKNISEYFVIEEEDVYLSASIGIVMAPADGE
DEKILFQRVDAALEKAKEKGKGHYHFYCSGLDCEREQRFIIENQLHRAIEKNEFFLYYQPQINIETKKIASMEALIRWEN
KELGFVSPNQFIPLAERTGFIIKLDEWVVNQVCQQLREWLNKGYEVVPIAVNISARHFRSITLIEMITRALNKYNVSAHL
LAIEVTEGALIHKDISKRVLLQLKEQNLKIHLDDFGTGYSSLSYLKTYPIDTLKIDRSFMEGIHIDERDTNITAAIIHLA
HTLELNIIAEGVEKKEQIQFLKEKNVKLVQGYYYSRPLSKYDMENMYYK

Sequences:

>Translated_689_residues
MKEEYSHQNTFLSMIDMDLIRQGLLHAIQDLVFILKVIDNETFQYMYVNKIGMDYARLSEECYGKTFAEVLPKDIAGILQ
RQYAKVVREAKAHTFCDVVNLPKGEIHYESSLNPVCDEEGICQFVICITRDITAQIEEKTKIEEKQMLFKSLLEYNNDSI
ISIDSIGRVTYANPATYEIFGYRYEELNNKFIFEFINKEYEKDFQIIFKGSMQGKAKQIVSKKYVHKEGYELYISLRTIP
IIVNGEIVGIYIVTRDVTRQVLNEMRTEYLAYYDQLTGLMNRISCTNKLNTFLNESVNFALVFIDLDEFHRINDTFGHKE
GDKVLQKVTECLSNLKIEDMHLFREHDDQFVMLIENITKEYVEEVAKSILKNISEYFVIEEEDVYLSASIGIVMAPADGE
DEKILFQRVDAALEKAKEKGKGHYHFYCSGLDCEREQRFIIENQLHRAIEKNEFFLYYQPQINIETKKIASMEALIRWEN
KELGFVSPNQFIPLAERTGFIIKLDEWVVNQVCQQLREWLNKGYEVVPIAVNISARHFRSITLIEMITRALNKYNVSAHL
LAIEVTEGALIHKDISKRVLLQLKEQNLKIHLDDFGTGYSSLSYLKTYPIDTLKIDRSFMEGIHIDERDTNITAAIIHLA
HTLELNIIAEGVEKKEQIQFLKEKNVKLVQGYYYSRPLSKYDMENMYYK
>Mature_689_residues
MKEEYSHQNTFLSMIDMDLIRQGLLHAIQDLVFILKVIDNETFQYMYVNKIGMDYARLSEECYGKTFAEVLPKDIAGILQ
RQYAKVVREAKAHTFCDVVNLPKGEIHYESSLNPVCDEEGICQFVICITRDITAQIEEKTKIEEKQMLFKSLLEYNNDSI
ISIDSIGRVTYANPATYEIFGYRYEELNNKFIFEFINKEYEKDFQIIFKGSMQGKAKQIVSKKYVHKEGYELYISLRTIP
IIVNGEIVGIYIVTRDVTRQVLNEMRTEYLAYYDQLTGLMNRISCTNKLNTFLNESVNFALVFIDLDEFHRINDTFGHKE
GDKVLQKVTECLSNLKIEDMHLFREHDDQFVMLIENITKEYVEEVAKSILKNISEYFVIEEEDVYLSASIGIVMAPADGE
DEKILFQRVDAALEKAKEKGKGHYHFYCSGLDCEREQRFIIENQLHRAIEKNEFFLYYQPQINIETKKIASMEALIRWEN
KELGFVSPNQFIPLAERTGFIIKLDEWVVNQVCQQLREWLNKGYEVVPIAVNISARHFRSITLIEMITRALNKYNVSAHL
LAIEVTEGALIHKDISKRVLLQLKEQNLKIHLDDFGTGYSSLSYLKTYPIDTLKIDRSFMEGIHIDERDTNITAAIIHLA
HTLELNIIAEGVEKKEQIQFLKEKNVKLVQGYYYSRPLSKYDMENMYYK

Specific function: Probable signaling protein whose physiological role is not yet known [H]

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=437, Percent_Identity=32.7231121281465, Blast_Score=269, Evalue=6e-73,
Organism=Escherichia coli, GI87081921, Length=419, Percent_Identity=31.7422434367542, Blast_Score=240, Evalue=3e-64,
Organism=Escherichia coli, GI226510982, Length=321, Percent_Identity=31.1526479750779, Blast_Score=169, Evalue=5e-43,
Organism=Escherichia coli, GI1790496, Length=246, Percent_Identity=35.3658536585366, Blast_Score=167, Evalue=3e-42,
Organism=Escherichia coli, GI87081845, Length=243, Percent_Identity=37.8600823045267, Blast_Score=162, Evalue=6e-41,
Organism=Escherichia coli, GI87081743, Length=240, Percent_Identity=34.5833333333333, Blast_Score=155, Evalue=7e-39,
Organism=Escherichia coli, GI87081980, Length=250, Percent_Identity=35.2, Blast_Score=155, Evalue=1e-38,
Organism=Escherichia coli, GI1786507, Length=258, Percent_Identity=33.3333333333333, Blast_Score=145, Evalue=9e-36,
Organism=Escherichia coli, GI1788502, Length=240, Percent_Identity=30.8333333333333, Blast_Score=134, Evalue=3e-32,
Organism=Escherichia coli, GI1787055, Length=420, Percent_Identity=24.5238095238095, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1788849, Length=443, Percent_Identity=27.0880361173815, Blast_Score=116, Evalue=5e-27,
Organism=Escherichia coli, GI1788381, Length=406, Percent_Identity=26.6009852216749, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI87082096, Length=313, Percent_Identity=26.517571884984, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI87081881, Length=288, Percent_Identity=27.4305555555556, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI145693134, Length=173, Percent_Identity=31.2138728323699, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1789650, Length=426, Percent_Identity=21.1267605633803, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI87082007, Length=183, Percent_Identity=27.8688524590164, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1788956, Length=139, Percent_Identity=30.2158273381295, Blast_Score=66, Evalue=9e-12,
Organism=Escherichia coli, GI1788085, Length=159, Percent_Identity=27.6729559748428, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1787262, Length=206, Percent_Identity=26.2135922330097, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 80483; Mature: 80483

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS50112 PAS ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEEYSHQNTFLSMIDMDLIRQGLLHAIQDLVFILKVIDNETFQYMYVNKIGMDYARLSE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHCCCHHHHHH
ECYGKTFAEVLPKDIAGILQRQYAKVVREAKAHTFCDVVNLPKGEIHYESSLNPVCDEEG
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCC
ICQFVICITRDITAQIEEKTKIEEKQMLFKSLLEYNNDSIISIDSIGRVTYANPATYEIF
CEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEECCCCEEEEE
GYRYEELNNKFIFEFINKEYEKDFQIIFKGSMQGKAKQIVSKKYVHKEGYELYISLRTIP
CEEHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEEEEEE
IIVNGEIVGIYIVTRDVTRQVLNEMRTEYLAYYDQLTGLMNRISCTNKLNTFLNESVNFA
EEECCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
LVFIDLDEFHRINDTFGHKEGDKVLQKVTECLSNLKIEDMHLFREHDDQFVMLIENITKE
EEEEEHHHHHHCCHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEHHHHHHHHH
YVEEVAKSILKNISEYFVIEEEDVYLSASIGIVMAPADGEDEKILFQRVDAALEKAKEKG
HHHHHHHHHHHHHHHHEEEECCCEEEEEECCEEEECCCCCCHHHHHHHHHHHHHHHHHHC
KGHYHFYCSGLDCEREQRFIIENQLHRAIEKNEFFLYYQPQINIETKKIASMEALIRWEN
CCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHEECC
KELGFVSPNQFIPLAERTGFIIKLDEWVVNQVCQQLREWLNKGYEVVPIAVNISARHFRS
CCCCCCCCCCCEEHHHCCCEEEEEHHHHHHHHHHHHHHHHHCCCEEEEEEEEECHHHHHH
ITLIEMITRALNKYNVSAHLLAIEVTEGALIHKDISKRVLLQLKEQNLKIHLDDFGTGYS
HHHHHHHHHHHHHCCCEEEEEEEEECCCEEEHHHHHHHHHHHHHCCCCEEEEECCCCCCH
SLSYLKTYPIDTLKIDRSFMEGIHIDERDTNITAAIIHLAHTLELNIIAEGVEKKEQIQF
HHHHHHHCCCCCEEECHHHHCCCCCCCCCCCHHHHHHHHHHHHEEEEEHHCCCHHHHHHH
LKEKNVKLVQGYYYSRPLSKYDMENMYYK
HHHCCCEEEECCHHCCCCCHHCCHHCCCC
>Mature Secondary Structure
MKEEYSHQNTFLSMIDMDLIRQGLLHAIQDLVFILKVIDNETFQYMYVNKIGMDYARLSE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHCCCHHHHHH
ECYGKTFAEVLPKDIAGILQRQYAKVVREAKAHTFCDVVNLPKGEIHYESSLNPVCDEEG
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCC
ICQFVICITRDITAQIEEKTKIEEKQMLFKSLLEYNNDSIISIDSIGRVTYANPATYEIF
CEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEECCCCEEEEE
GYRYEELNNKFIFEFINKEYEKDFQIIFKGSMQGKAKQIVSKKYVHKEGYELYISLRTIP
CEEHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEEEEEE
IIVNGEIVGIYIVTRDVTRQVLNEMRTEYLAYYDQLTGLMNRISCTNKLNTFLNESVNFA
EEECCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
LVFIDLDEFHRINDTFGHKEGDKVLQKVTECLSNLKIEDMHLFREHDDQFVMLIENITKE
EEEEEHHHHHHCCHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEHHHHHHHHH
YVEEVAKSILKNISEYFVIEEEDVYLSASIGIVMAPADGEDEKILFQRVDAALEKAKEKG
HHHHHHHHHHHHHHHHEEEECCCEEEEEECCEEEECCCCCCHHHHHHHHHHHHHHHHHHC
KGHYHFYCSGLDCEREQRFIIENQLHRAIEKNEFFLYYQPQINIETKKIASMEALIRWEN
CCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHEECC
KELGFVSPNQFIPLAERTGFIIKLDEWVVNQVCQQLREWLNKGYEVVPIAVNISARHFRS
CCCCCCCCCCCEEHHHCCCEEEEEHHHHHHHHHHHHHHHHHCCCEEEEEEEEECHHHHHH
ITLIEMITRALNKYNVSAHLLAIEVTEGALIHKDISKRVLLQLKEQNLKIHLDDFGTGYS
HHHHHHHHHHHHHCCCEEEEEEEEECCCEEEHHHHHHHHHHHHHCCCCEEEEECCCCCCH
SLSYLKTYPIDTLKIDRSFMEGIHIDERDTNITAAIIHLAHTLELNIIAEGVEKKEQIQF
HHHHHHHCCCCCEEECHHHHCCCCCCCCCCCHHHHHHHHHHHHEEEEEHHCCCHHHHHHH
LKEKNVKLVQGYYYSRPLSKYDMENMYYK
HHHCCCEEEECCHHCCCCCHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 11728710 [H]