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The map label for this gene is kipR [H]

Identifier: 218234495

GI number: 218234495

Start: 2961424

End: 2962176

Strand: Reverse

Name: kipR [H]

Synonym: BCB4264_A3089

Alternate gene names: 218234495

Gene position: 2962176-2961424 (Counterclockwise)

Preceding gene: 218233635

Following gene: 218235467

Centisome position: 54.66

GC content: 37.85

Gene sequence:

>753_bases
ATGAGTATAAATAAAACGGCAGTTAAGACAATGGATATTTTAGAGTTGTTTTATGAGCATGAAGAGCTAAGTTTAACTGA
GATGGTTCAGCTTACAAATATGCCGAAAACATCTGTTTATCGTTTAATTGGTTCGTTGGAAGAGATGGAGTTTTTACAAA
AAAACGAAAAGGGGAAATATCGTTTAGGGGTCGTATTTTTACGGTTCGGTCAACTTGTTTCACACCGATTATCAGTAAGA
AATATAGCAATTCCTTATATGAAAGAACTTAGTGATAGTTTAGGACAGGCAGTTAATTTAATAATTCAGGATGGAAATGA
CGCAATTTATGTTGAAAAAATGGAAGGTGTTCAGCCTGTACGCGTGTATACGGCGGTTGGAAGAAGAGCACCGCTTTATG
CTGGCGCATGTCCAAGAATTTTACTATCGTATTTCTCTGAGGAAGAGAAACGGAGATACATAGAGGAAGTGGATTTAAAA
CAGTTTGCAGATGGAACAATCGTGGATAAGAAACAATTGTTAGAAGTGTTGCAAATGGCAAAAAAGGAAGGCTACACCAT
TAGTTATTCTGAGTTAGAAAATCATACAGCCGCGATAGCAGCACCCATTTTCGCGAGCGATGGAACGGTTGTAGCAGGCA
TTAGTATTTCGGGATTAGCAATTGAGTACAACGAAAGTAACATTTCATATTTTATTGCGAAGGTGAAAGAAACAGCGCAT
CGCATTTCGAAAGAACTCGGCTTTTTGGCATAG

Upstream 100 bases:

>100_bases
CTATTGATTGAATTGAAAGAATATTTTATAATTTTAAATTATATGTTTGTTTCGAAAAACGGAATTTAAGTTCCGTAATT
CGGAACGAAAGGGAGATAGA

Downstream 100 bases:

>100_bases
AAAGAGGGAGTAGGATGAGATTTTCTGCGTTAGGGGATCAAGCAATTATTGTTACATTTGGTGAAGAAATTAAGAGGGAT
ATATATGAGAAAGTACAGCG

Product: transcriptional regulator, IclR family

Products: NA

Alternate protein names: Kip operon repressor protein [H]

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MSINKTAVKTMDILELFYEHEELSLTEMVQLTNMPKTSVYRLIGSLEEMEFLQKNEKGKYRLGVVFLRFGQLVSHRLSVR
NIAIPYMKELSDSLGQAVNLIIQDGNDAIYVEKMEGVQPVRVYTAVGRRAPLYAGACPRILLSYFSEEEKRRYIEEVDLK
QFADGTIVDKKQLLEVLQMAKKEGYTISYSELENHTAAIAAPIFASDGTVVAGISISGLAIEYNESNISYFIAKVKETAH
RISKELGFLA

Sequences:

>Translated_250_residues
MSINKTAVKTMDILELFYEHEELSLTEMVQLTNMPKTSVYRLIGSLEEMEFLQKNEKGKYRLGVVFLRFGQLVSHRLSVR
NIAIPYMKELSDSLGQAVNLIIQDGNDAIYVEKMEGVQPVRVYTAVGRRAPLYAGACPRILLSYFSEEEKRRYIEEVDLK
QFADGTIVDKKQLLEVLQMAKKEGYTISYSELENHTAAIAAPIFASDGTVVAGISISGLAIEYNESNISYFIAKVKETAH
RISKELGFLA
>Mature_249_residues
SINKTAVKTMDILELFYEHEELSLTEMVQLTNMPKTSVYRLIGSLEEMEFLQKNEKGKYRLGVVFLRFGQLVSHRLSVRN
IAIPYMKELSDSLGQAVNLIIQDGNDAIYVEKMEGVQPVRVYTAVGRRAPLYAGACPRILLSYFSEEEKRRYIEEVDLKQ
FADGTIVDKKQLLEVLQMAKKEGYTISYSELENHTAAIAAPIFASDGTVVAGISISGLAIEYNESNISYFIAKVKETAHR
ISKELGFLA

Specific function: Transcriptional repressor of the kip gene-containing operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786468, Length=252, Percent_Identity=28.1746031746032, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1788131, Length=244, Percent_Identity=28.6885245901639, Blast_Score=123, Evalue=9e-30,
Organism=Escherichia coli, GI1786715, Length=219, Percent_Identity=32.4200913242009, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1788581, Length=244, Percent_Identity=26.2295081967213, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790752, Length=226, Percent_Identity=27.8761061946903, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1789999, Length=230, Percent_Identity=26.0869565217391, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87082359, Length=247, Percent_Identity=23.8866396761134, Blast_Score=85, Evalue=5e-18,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28176; Mature: 28045

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSINKTAVKTMDILELFYEHEELSLTEMVQLTNMPKTSVYRLIGSLEEMEFLQKNEKGKY
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCE
RLGVVFLRFGQLVSHRLSVRNIAIPYMKELSDSLGQAVNLIIQDGNDAIYVEKMEGVQPV
EHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHEEEEEECCCCEEEEEECCCCCHH
RVYTAVGRRAPLYAGACPRILLSYFSEEEKRRYIEEVDLKQFADGTIVDKKQLLEVLQMA
HHHHHHCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHHHH
KKEGYTISYSELENHTAAIAAPIFASDGTVVAGISISGLAIEYNESNISYFIAKVKETAH
HHCCCEEEHHHHHCCHHHHEECEEECCCCEEEEEEEEEEEEEECCCCHHHHHHHHHHHHH
RISKELGFLA
HHHHHHCCCC
>Mature Secondary Structure 
SINKTAVKTMDILELFYEHEELSLTEMVQLTNMPKTSVYRLIGSLEEMEFLQKNEKGKY
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCE
RLGVVFLRFGQLVSHRLSVRNIAIPYMKELSDSLGQAVNLIIQDGNDAIYVEKMEGVQPV
EHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHEEEEEECCCCEEEEEECCCCCHH
RVYTAVGRRAPLYAGACPRILLSYFSEEEKRRYIEEVDLKQFADGTIVDKKQLLEVLQMA
HHHHHHCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHHHH
KKEGYTISYSELENHTAAIAAPIFASDGTVVAGISISGLAIEYNESNISYFIAKVKETAH
HHCCCEEEHHHHHCCHHHHEECEEECCCCEEEEEEEEEEEEEECCCCHHHHHHHHHHHHH
RISKELGFLA
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]