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The map label for this gene is rihA [H]

Identifier: 218234397

GI number: 218234397

Start: 2785235

End: 2786200

Strand: Reverse

Name: rihA [H]

Synonym: BCB4264_A2904

Alternate gene names: 218234397

Gene position: 2786200-2785235 (Counterclockwise)

Preceding gene: 218233570

Following gene: 218235855

Centisome position: 51.42

GC content: 35.4

Gene sequence:

>966_bases
GTGAGAATAGTTAATAAGAAAATTATCTTTTTTGGAGATTTTGGTATTGATGACGCCGTAGCGTTAATTTATGCAAATAA
AACATGTAAATTAGATATTCTAGGTATTGTTGCTGAGTACGGGAATGTATCACGAGATATCGTTACGGAAAATGTTTATT
TTTTAGAAAGGTACTATGCTACACAAGTGAAAATTATTGAAGGTGCGAGTAGACCGATGACAGCTGAAGAGCCTTTGTTT
TTCCCTGAAATCCACGGGGATCACGGTTTAGGTCCTATTATTCCACCTGAGATGAGAATTTGTAAACGAGAAAATTTTTG
TGAATTAATCAAATTAATCGAACCTTGTCCAGAAGATATTATAATTGTGGCGACAGGGAGACTAACGACGCTTGCTACGT
TATTTTTATTGTATCCAAATATAATGGATCGTATTTGTTCGTATTATATAATGGGCGGCGCTTTCCTATTTCCAGGTAAT
GTTACACCAGTATCTGAAGCGAATTTTTATGGTGATCCAATTGCAGCAAATATTGTTATGAAATATGCGAAAAACGCTAG
CATATACCCGTTAAATGTAACACAGGGCGCGCTTATTACGCCTGAAATGGCCAATATAATAGATAAACAAGGAACTGGAC
AGGCGAAACTCATTAAACCAATGATTGATTTTTATTATGAGAATTTCTATAAAAAAGAATATCCGGGTATTGGTGGAAGT
CCTATACACGATTTACTACCGTTTATCTCGTTTATAAATGACAGTATTTTCGAATATAAAAAATCGGCAGTGTGGATTAG
TACGACAAATGATGTGACTAGGGGCCAAAGTGTAGCAGACTTTAGAAAAATAGCTGAGCCAACAAGGTTTGATGATCGGC
CGATTCAAAGAATTGCTGTTGGTTTTAACTATGCAGCTTTTAAAGAAGAGTTTATGCGAACAATATTGAAGCCAGATTGT
TCTTAA

Upstream 100 bases:

>100_bases
AGATTGAAGTCGCCAATAAATAGGCGACTTTTTTAGTTTGCGCTGTTTCACCGCCTTGTCTTTTTCACATAATAATAATA
GTAGATTATGCTTAAGAGGG

Downstream 100 bases:

>100_bases
TGTGTGTAATAACAAGTCGGATAAATCGTTAGTTCAAAAAAAGGTTTAATCTGTGTGTATTATTCTCAAAAATCTTAAAG
TTGAACAACATGAATAACTT

Product: inosine-uridine preferring nucleoside hydrolase family protein

Products: D-ribose; purine

Alternate protein names: Cytidine/uridine-specific hydrolase [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MRIVNKKIIFFGDFGIDDAVALIYANKTCKLDILGIVAEYGNVSRDIVTENVYFLERYYATQVKIIEGASRPMTAEEPLF
FPEIHGDHGLGPIIPPEMRICKRENFCELIKLIEPCPEDIIIVATGRLTTLATLFLLYPNIMDRICSYYIMGGAFLFPGN
VTPVSEANFYGDPIAANIVMKYAKNASIYPLNVTQGALITPEMANIIDKQGTGQAKLIKPMIDFYYENFYKKEYPGIGGS
PIHDLLPFISFINDSIFEYKKSAVWISTTNDVTRGQSVADFRKIAEPTRFDDRPIQRIAVGFNYAAFKEEFMRTILKPDC
S

Sequences:

>Translated_321_residues
MRIVNKKIIFFGDFGIDDAVALIYANKTCKLDILGIVAEYGNVSRDIVTENVYFLERYYATQVKIIEGASRPMTAEEPLF
FPEIHGDHGLGPIIPPEMRICKRENFCELIKLIEPCPEDIIIVATGRLTTLATLFLLYPNIMDRICSYYIMGGAFLFPGN
VTPVSEANFYGDPIAANIVMKYAKNASIYPLNVTQGALITPEMANIIDKQGTGQAKLIKPMIDFYYENFYKKEYPGIGGS
PIHDLLPFISFINDSIFEYKKSAVWISTTNDVTRGQSVADFRKIAEPTRFDDRPIQRIAVGFNYAAFKEEFMRTILKPDC
S
>Mature_321_residues
MRIVNKKIIFFGDFGIDDAVALIYANKTCKLDILGIVAEYGNVSRDIVTENVYFLERYYATQVKIIEGASRPMTAEEPLF
FPEIHGDHGLGPIIPPEMRICKRENFCELIKLIEPCPEDIIIVATGRLTTLATLFLLYPNIMDRICSYYIMGGAFLFPGN
VTPVSEANFYGDPIAANIVMKYAKNASIYPLNVTQGALITPEMANIIDKQGTGQAKLIKPMIDFYYENFYKKEYPGIGGS
PIHDLLPFISFINDSIFEYKKSAVWISTTNDVTRGQSVADFRKIAEPTRFDDRPIQRIAVGFNYAAFKEEFMRTILKPDC
S

Specific function: Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively [H]

COG id: COG1957

COG function: function code F; Inosine-uridine nucleoside N-ribohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IUNH family. RihA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786871, Length=277, Percent_Identity=29.9638989169675, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1788486, Length=277, Percent_Identity=27.0758122743682, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786213, Length=271, Percent_Identity=26.9372693726937, Blast_Score=75, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6320608, Length=256, Percent_Identity=30.078125, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015910
- InterPro:   IPR023186
- InterPro:   IPR001910
- InterPro:   IPR022975 [H]

Pfam domain/function: PF01156 IU_nuc_hydro [H]

EC number: 3.2.2.1

Molecular weight: Translated: 36233; Mature: 36233

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVNKKIIFFGDFGIDDAVALIYANKTCKLDILGIVAEYGNVSRDIVTENVYFLERYYA
CCEECCEEEEEECCCCCCEEEEEEECCCCEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHH
TQVKIIEGASRPMTAEEPLFFPEIHGDHGLGPIIPPEMRICKRENFCELIKLIEPCPEDI
HEEEEEECCCCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHCCCCCCE
IIVATGRLTTLATLFLLYPNIMDRICSYYIMGGAFLFPGNVTPVSEANFYGDPIAANIVM
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCCHHHHHHH
KYAKNASIYPLNVTQGALITPEMANIIDKQGTGQAKLIKPMIDFYYENFYKKEYPGIGGS
HHHCCCCEEEEECCCCCEECCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
PIHDLLPFISFINDSIFEYKKSAVWISTTNDVTRGQSVADFRKIAEPTRFDDRPIQRIAV
CHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHH
GFNYAAFKEEFMRTILKPDCS
CCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRIVNKKIIFFGDFGIDDAVALIYANKTCKLDILGIVAEYGNVSRDIVTENVYFLERYYA
CCEECCEEEEEECCCCCCEEEEEEECCCCEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHH
TQVKIIEGASRPMTAEEPLFFPEIHGDHGLGPIIPPEMRICKRENFCELIKLIEPCPEDI
HEEEEEECCCCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHCCCCCCE
IIVATGRLTTLATLFLLYPNIMDRICSYYIMGGAFLFPGNVTPVSEANFYGDPIAANIVM
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCCHHHHHHH
KYAKNASIYPLNVTQGALITPEMANIIDKQGTGQAKLIKPMIDFYYENFYKKEYPGIGGS
HHHCCCCEEEEECCCCCEECCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
PIHDLLPFISFINDSIFEYKKSAVWISTTNDVTRGQSVADFRKIAEPTRFDDRPIQRIAV
CHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHH
GFNYAAFKEEFMRTILKPDCS
CCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-D-ribosylpurine; H2O

Specific reaction: an N-D-ribosylpurine + H2O = D-ribose + a purine

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA