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The map label for this gene is yurR [H]

Identifier: 218234169

GI number: 218234169

Start: 2635891

End: 2637006

Strand: Reverse

Name: yurR [H]

Synonym: BCB4264_A2732

Alternate gene names: 218234169

Gene position: 2637006-2635891 (Counterclockwise)

Preceding gene: 218234902

Following gene: 218233387

Centisome position: 48.66

GC content: 39.16

Gene sequence:

>1116_bases
ATGAAATCGTATATTGTAGTTGGATCTGGAATTTTAGGAGCGTCTACTGCTTATCATCTTGCTAAGACAGGTGCGAATGT
TACTATCGTGGATCGCCAACAATTAGGGCAAGCAACTGATGCAGGAGCAGGAATTGTATGTCCATGGTTATCACAGCGTC
GTAATAAAGCATGGTATAAAATTGTTAAAGGCGGTGCACGTTACTATTCTTCGTTAATTCAGCAATTAGAAGAAGACGGT
GAAACTGACACAGGATATAATCGTGTAGGTGCAATTAGTTTACATACTGACGAGAAAAAGTTAGATCAAATGGAAGAGCG
AGCTTATAAACGACGTGAAGATGCCCCGGAGATTGGTGAAATCACTCGCTTATCAGCTGAAGAAACAAAAAAATTATTCC
CAGCATTATCAGACGAATATAGTTCTGTTCATATTAGTGGTGCTGCACGAGTAAATGGGAGATTATTACGCAATGCATTA
ATAAGTGCTGCGAAAAAACATGGTGCAACTTTCATAAAAGGCGATGCTATATTAGTCCGTGAAGGAAATCATATTACGGG
AGTTACAGTAAACGATGAAACAATTTTAGCAGAAAAGGTTATTGTAACTGCAGGCGCATGGGCGAATGAAATCTTGAAAC
CATTAGGAATTAATTTCTTAGTTACATTCCAAAAAGGACAAATTGTTCATCTGCAAATCGAGAATACAGCAACAGAAAAT
ATGCCAGTTGTTATGCCACCGAACGATCAATATATTTTAACGTTTGACAATGGGCATGTCGTAATTGGTGCAACACATGA
GAATGATACTGGTTTTGATCATCGTGTAACAGCAGGTGGTTTACATGAAGTATTCCATAAGGCATTAACAGTTGCGCCTG
GCTTAGAAAATGCTACAATGCTTGAAACGAGAGTTGGATTCAGACCATTTACACCAGGATTCTTACCTGTTATCGGACCG
CTACCTAACTTTGAAGGAATTCTCGTTGCGAATGGATTAGGGGCTTCGGGTTTAACAGCTGGTCCATATCTAGGAGCGGA
ACTTGCTAAACTAGCGCTCGGAAAAACGATTGAATTAGATTTAAATGATTATGATGTTGCTGGCGCAATTGAATAA

Upstream 100 bases:

>100_bases
CAATTAATTGTGATGAGTACATTGAAAAAAGCATTCCTTCCATTATACTAAGGAATGTTCTTATATTTATATAATTAGCA
AAAGAGAAAAGGTGTTTGAA

Downstream 100 bases:

>100_bases
TATAGGGTACTGCTAACATTTAGGAAAAACCATGCTAAACAAATTCGACAAGAAATAATCAGTTTTTCCTCTGTTAAGAG
TAAGCCTGTTTATGAAAAAT

Product: oxidoreductase, DadA family

Products: 2-oxo acid; NH3; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MKSYIVVGSGILGASTAYHLAKTGANVTIVDRQQLGQATDAGAGIVCPWLSQRRNKAWYKIVKGGARYYSSLIQQLEEDG
ETDTGYNRVGAISLHTDEKKLDQMEERAYKRREDAPEIGEITRLSAEETKKLFPALSDEYSSVHISGAARVNGRLLRNAL
ISAAKKHGATFIKGDAILVREGNHITGVTVNDETILAEKVIVTAGAWANEILKPLGINFLVTFQKGQIVHLQIENTATEN
MPVVMPPNDQYILTFDNGHVVIGATHENDTGFDHRVTAGGLHEVFHKALTVAPGLENATMLETRVGFRPFTPGFLPVIGP
LPNFEGILVANGLGASGLTAGPYLGAELAKLALGKTIELDLNDYDVAGAIE

Sequences:

>Translated_371_residues
MKSYIVVGSGILGASTAYHLAKTGANVTIVDRQQLGQATDAGAGIVCPWLSQRRNKAWYKIVKGGARYYSSLIQQLEEDG
ETDTGYNRVGAISLHTDEKKLDQMEERAYKRREDAPEIGEITRLSAEETKKLFPALSDEYSSVHISGAARVNGRLLRNAL
ISAAKKHGATFIKGDAILVREGNHITGVTVNDETILAEKVIVTAGAWANEILKPLGINFLVTFQKGQIVHLQIENTATEN
MPVVMPPNDQYILTFDNGHVVIGATHENDTGFDHRVTAGGLHEVFHKALTVAPGLENATMLETRVGFRPFTPGFLPVIGP
LPNFEGILVANGLGASGLTAGPYLGAELAKLALGKTIELDLNDYDVAGAIE
>Mature_371_residues
MKSYIVVGSGILGASTAYHLAKTGANVTIVDRQQLGQATDAGAGIVCPWLSQRRNKAWYKIVKGGARYYSSLIQQLEEDG
ETDTGYNRVGAISLHTDEKKLDQMEERAYKRREDAPEIGEITRLSAEETKKLFPALSDEYSSVHISGAARVNGRLLRNAL
ISAAKKHGATFIKGDAILVREGNHITGVTVNDETILAEKVIVTAGAWANEILKPLGINFLVTFQKGQIVHLQIENTATEN
MPVVMPPNDQYILTFDNGHVVIGATHENDTGFDHRVTAGGLHEVFHKALTVAPGLENATMLETRVGFRPFTPGFLPVIGP
LPNFEGILVANGLGASGLTAGPYLGAELAKLALGKTIELDLNDYDVAGAIE

Specific function: Oxidative Deamination Of D-Amino Acids. [C]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Inner Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DadA oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=390, Percent_Identity=26.6666666666667, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI21361378, Length=390, Percent_Identity=26.6666666666667, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI24797151, Length=392, Percent_Identity=23.2142857142857, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71994045, Length=389, Percent_Identity=22.879177377892, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI20130091, Length=384, Percent_Identity=26.5625, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: 1.4.99.1

Molecular weight: Translated: 39968; Mature: 39968

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSYIVVGSGILGASTAYHLAKTGANVTIVDRQQLGQATDAGAGIVCPWLSQRRNKAWYK
CCCEEEEECCCCCCHHHHHHHHCCCCEEEEEHHHCCCCCCCCCCEECCCHHHHCCHHHHH
IVKGGARYYSSLIQQLEEDGETDTGYNRVGAISLHTDEKKLDQMEERAYKRREDAPEIGE
HHHCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHCCCCCHHH
ITRLSAEETKKLFPALSDEYSSVHISGAARVNGRLLRNALISAAKKHGATFIKGDAILVR
HHCCCHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEECCEEEEE
EGNHITGVTVNDETILAEKVIVTAGAWANEILKPLGINFLVTFQKGQIVHLQIENTATEN
CCCEEEEEEECCCEEEEEEEEEECCCCHHHHHHHCCCEEEEEEECCCEEEEEECCCCCCC
MPVVMPPNDQYILTFDNGHVVIGATHENDTGFDHRVTAGGLHEVFHKALTVAPGLENATM
CCEEECCCCCEEEEECCCEEEEEEECCCCCCCCCEECCCHHHHHHHHHHHCCCCCCCCEE
LETRVGFRPFTPGFLPVIGPLPNFEGILVANGLGASGLTAGPYLGAELAKLALGKTIELD
EEHCCCCCCCCCCCCHHCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCEEEEE
LNDYDVAGAIE
CCCCCCCCCCC
>Mature Secondary Structure
MKSYIVVGSGILGASTAYHLAKTGANVTIVDRQQLGQATDAGAGIVCPWLSQRRNKAWYK
CCCEEEEECCCCCCHHHHHHHHCCCCEEEEEHHHCCCCCCCCCCEECCCHHHHCCHHHHH
IVKGGARYYSSLIQQLEEDGETDTGYNRVGAISLHTDEKKLDQMEERAYKRREDAPEIGE
HHHCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHCCCCCHHH
ITRLSAEETKKLFPALSDEYSSVHISGAARVNGRLLRNALISAAKKHGATFIKGDAILVR
HHCCCHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEECCEEEEE
EGNHITGVTVNDETILAEKVIVTAGAWANEILKPLGINFLVTFQKGQIVHLQIENTATEN
CCCEEEEEEECCCEEEEEEEEEECCCCHHHHHHHCCCEEEEEEECCCEEEEEECCCCCCC
MPVVMPPNDQYILTFDNGHVVIGATHENDTGFDHRVTAGGLHEVFHKALTVAPGLENATM
CCEEECCCCCEEEEECCCEEEEEEECCCCCCCCCEECCCHHHHHHHHHHHCCCCCCCCEE
LETRVGFRPFTPGFLPVIGPLPNFEGILVANGLGASGLTAGPYLGAELAKLALGKTIELD
EEHCCCCCCCCCCCCHHCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCEEEEE
LNDYDVAGAIE
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Iron [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 40 {D-proline}} 0.13 {K3Fe(CN)6}} 11 {D-methionine}} 6 {D-phenylalanine}} 12 {D-alpha-aminobutyrate}} 14 {D-glutamine}} 0.63 {dichloroindophenol}} 0.01 {dichloroindophenol}} 0.15 {cytochrome} 19 {D-serine}} 29 {D-alanine}} 6.4

Substrates: D-amino acid; H2O; acceptor

Specific reaction: a D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor

General reaction: Oxidative deamination; Redox reaction [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]