Click here to switch to the map view.

The map label for this gene is aroA [H]

Identifier: 218234153

GI number: 218234153

Start: 2827978

End: 2829267

Strand: Reverse

Name: aroA [H]

Synonym: BCB4264_A2956

Alternate gene names: 218234153

Gene position: 2829267-2827978 (Counterclockwise)

Preceding gene: 218233603

Following gene: 218235397

Centisome position: 52.21

GC content: 38.37

Gene sequence:

>1290_bases
GTGAAAGAAAGAACAATACAACCTGTTAATAACGGATTGAATGGCAATATTACAATCCCAGGTGATAAATCCATTTCACA
CCGTGCTGTTATGTTCGGTTCTATTGCAGAAGGGAAAACAACAATTAAAGGTTTCTTGCCCGGTGCAGACTGTTTAAGTA
CGATTTCATGTTTTAAAGAAATGGGAGTAGAAATTACGCAAAACGGTGATGAGGTTACTGTAGTTGGTAAAGGATTAGAA
GGTTTACAAGAACCAAAAGCTGTATTAGATGTTGGTAATTCTGGTACAACAATCCGATTAATGTCAGGTATATTAGCTAA
CACACCATTTTTCTCTTGCGTACAAGGTGATGAATCTATCGCAAAAAGACCGATGAAGCGTGTAACAAACCCATTAAAAC
AAATGGGCGCAAACATAGACGGCCGAGAAGAAGGAACATTTACACCGTTAACAATACGTGGCGGAGATTTAAAAGCAATT
GAATATATTTCTCCTGTTGCAAGTGCACAAGTAAAGTCAGCTATTTTACTTGCAGGTCTTCGTGCAGAAGGTGTAACAGC
TGTTACAGAACCACATATTTCACGCGACCATACGGAAAGAATGCTCGAAGCATTTGGTGTTAAAGTAACTCGCGAAGGGA
AAACAGTGAAGCTGTCAGGTGGACAAAAATTAACAGCAACAGACATTCAAGTGCCCGGTGACGTATCATCAGCAGCATTT
TTCTTAGTAGCAGGTGCAATCATCCCAAATAGTAAACTAGTATTACAAAATGTAGGAATGAATCCAACCCGTACAGGTAT
TATTGATGTTTTAGAAAAAATGGGTGCTACGTTCACTGTAGACCTAATTAACGAAGGGGCATCAGAACCAGCTGCAAATA
TTACAATCGAAACATCTTCATTAAAAGGAATTGAAATTGGCGGAGATATTATCCCTAGATTAATCGATGAGATTCCTGTA
ATCGCATTAGCGGCAACGCAAGCAGAAGGAATTACAGTAATTAAAGATGCACACGAATTAAAAGTAAAAGAAACAAACCG
TATTGATACAGTAGTTGCTGAGTTAACGAAACTAGGAGCTCGAATAGAAGCAACTGATGACGGTATGATCATTTACGGAA
AATCAGCTCTAAAAGGCAATACAGTAAATAGTTATGGTGATCACCGTATCGGAATGATGCTTGCAATTGCTGGCTGCCTA
GCAGAAGGAAAAACAATTATTGAAGATGCAGAAGCAGTAGGTGTATCATATCCTACATTCTTTGACGAACTTCAAAAGTT
AGCTAAATAA

Upstream 100 bases:

>100_bases
TTAGCTTCCAAAGGGAAGAAGATCGTATGAAAGCAAAACTAGCGCTTGGAGAAGAAGAATACCAAACTTATGAAACAATT
TAAATGAGAAGGTGAAAAAC

Downstream 100 bases:

>100_bases
AAAGGGTGGAAAGCAGATACGTGATGTATCTGCTTTTTTGTTAAAACGTCCTTGTAATTTCACTTACCGAACTATAATAG
TGAGAATTATGATACAATTC

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MKERTIQPVNNGLNGNITIPGDKSISHRAVMFGSIAEGKTTIKGFLPGADCLSTISCFKEMGVEITQNGDEVTVVGKGLE
GLQEPKAVLDVGNSGTTIRLMSGILANTPFFSCVQGDESIAKRPMKRVTNPLKQMGANIDGREEGTFTPLTIRGGDLKAI
EYISPVASAQVKSAILLAGLRAEGVTAVTEPHISRDHTERMLEAFGVKVTREGKTVKLSGGQKLTATDIQVPGDVSSAAF
FLVAGAIIPNSKLVLQNVGMNPTRTGIIDVLEKMGATFTVDLINEGASEPAANITIETSSLKGIEIGGDIIPRLIDEIPV
IALAATQAEGITVIKDAHELKVKETNRIDTVVAELTKLGARIEATDDGMIIYGKSALKGNTVNSYGDHRIGMMLAIAGCL
AEGKTIIEDAEAVGVSYPTFFDELQKLAK

Sequences:

>Translated_429_residues
MKERTIQPVNNGLNGNITIPGDKSISHRAVMFGSIAEGKTTIKGFLPGADCLSTISCFKEMGVEITQNGDEVTVVGKGLE
GLQEPKAVLDVGNSGTTIRLMSGILANTPFFSCVQGDESIAKRPMKRVTNPLKQMGANIDGREEGTFTPLTIRGGDLKAI
EYISPVASAQVKSAILLAGLRAEGVTAVTEPHISRDHTERMLEAFGVKVTREGKTVKLSGGQKLTATDIQVPGDVSSAAF
FLVAGAIIPNSKLVLQNVGMNPTRTGIIDVLEKMGATFTVDLINEGASEPAANITIETSSLKGIEIGGDIIPRLIDEIPV
IALAATQAEGITVIKDAHELKVKETNRIDTVVAELTKLGARIEATDDGMIIYGKSALKGNTVNSYGDHRIGMMLAIAGCL
AEGKTIIEDAEAVGVSYPTFFDELQKLAK
>Mature_429_residues
MKERTIQPVNNGLNGNITIPGDKSISHRAVMFGSIAEGKTTIKGFLPGADCLSTISCFKEMGVEITQNGDEVTVVGKGLE
GLQEPKAVLDVGNSGTTIRLMSGILANTPFFSCVQGDESIAKRPMKRVTNPLKQMGANIDGREEGTFTPLTIRGGDLKAI
EYISPVASAQVKSAILLAGLRAEGVTAVTEPHISRDHTERMLEAFGVKVTREGKTVKLSGGQKLTATDIQVPGDVSSAAF
FLVAGAIIPNSKLVLQNVGMNPTRTGIIDVLEKMGATFTVDLINEGASEPAANITIETSSLKGIEIGGDIIPRLIDEIPV
IALAATQAEGITVIKDAHELKVKETNRIDTVVAELTKLGARIEATDDGMIIYGKSALKGNTVNSYGDHRIGMMLAIAGCL
AEGKTIIEDAEAVGVSYPTFFDELQKLAK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=443, Percent_Identity=28.2167042889391, Blast_Score=147, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6320332, Length=457, Percent_Identity=25.164113785558, Blast_Score=102, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 45316; Mature: 45316

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKERTIQPVNNGLNGNITIPGDKSISHRAVMFGSIAEGKTTIKGFLPGADCLSTISCFKE
CCCCCCCHHCCCCCCCEECCCCCCCCCEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHH
MGVEITQNGDEVTVVGKGLEGLQEPKAVLDVGNSGTTIRLMSGILANTPFFSCVQGDESI
CCCEEECCCCEEEEEECCCCCHHCCHHHEECCCCCCEEHHHHHHHHCCCCCEEECCCHHH
AKRPMKRVTNPLKQMGANIDGREEGTFTPLTIRGGDLKAIEYISPVASAQVKSAILLAGL
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCEEHHHHHHHHHHHHHHHHHHHCCC
RAEGVTAVTEPHISRDHTERMLEAFGVKVTREGKTVKLSGGQKLTATDIQVPGDVSSAAF
CCCCCEEECCCCCCHHHHHHHHHHHCCEEECCCCEEEECCCCEEEEEEEECCCCCHHHHH
FLVAGAIIPNSKLVLQNVGMNPTRTGIIDVLEKMGATFTVDLINEGASEPAANITIETSS
HHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEEHHCCCCCCCCEEEEEECC
LKGIEIGGDIIPRLIDEIPVIALAATQAEGITVIKDAHELKVKETNRIDTVVAELTKLGA
CCCEEECHHHHHHHHHHCCEEEEEECCCCCEEEEECCHHEEECCCCHHHHHHHHHHHHCC
RIEATDDGMIIYGKSALKGNTVNSYGDHRIGMMLAIAGCLAEGKTIIEDAEAVGVSYPTF
EEEECCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHH
FDELQKLAK
HHHHHHHCC
>Mature Secondary Structure
MKERTIQPVNNGLNGNITIPGDKSISHRAVMFGSIAEGKTTIKGFLPGADCLSTISCFKE
CCCCCCCHHCCCCCCCEECCCCCCCCCEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHH
MGVEITQNGDEVTVVGKGLEGLQEPKAVLDVGNSGTTIRLMSGILANTPFFSCVQGDESI
CCCEEECCCCEEEEEECCCCCHHCCHHHEECCCCCCEEHHHHHHHHCCCCCEEECCCHHH
AKRPMKRVTNPLKQMGANIDGREEGTFTPLTIRGGDLKAIEYISPVASAQVKSAILLAGL
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCEEHHHHHHHHHHHHHHHHHHHCCC
RAEGVTAVTEPHISRDHTERMLEAFGVKVTREGKTVKLSGGQKLTATDIQVPGDVSSAAF
CCCCCEEECCCCCCHHHHHHHHHHHCCEEECCCCEEEECCCCEEEEEEEECCCCCHHHHH
FLVAGAIIPNSKLVLQNVGMNPTRTGIIDVLEKMGATFTVDLINEGASEPAANITIETSS
HHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEEHHCCCCCCCCEEEEEECC
LKGIEIGGDIIPRLIDEIPVIALAATQAEGITVIKDAHELKVKETNRIDTVVAELTKLGA
CCCEEECHHHHHHHHHHCCEEEEEECCCCCEEEEECCHHEEECCCCHHHHHHHHHHHHCC
RIEATDDGMIIYGKSALKGNTVNSYGDHRIGMMLAIAGCLAEGKTIIEDAEAVGVSYPTF
EEEECCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHH
FDELQKLAK
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA