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The map label for this gene is esxA [H]

Identifier: 218234149

GI number: 218234149

Start: 933525

End: 933821

Strand: Direct

Name: esxA [H]

Synonym: BCB4264_A0959

Alternate gene names: 218234149

Gene position: 933525-933821 (Clockwise)

Preceding gene: 218232905

Following gene: 218231674

Centisome position: 17.23

GC content: 36.03

Gene sequence:

>297_bases
ATGGCTGGACAAATTCGTATGTCACCAGAGGAGCTTAAATCGAAAGCGGCTCGATATGGACAAGGTGCAAATCAAATTGA
GGACATTTTAAGTCAACTACAAAACTTACAAAATGAATTAAGAGGAGAATGGGAAGGTCGTGCTTTTGAAGGTTTTGACC
AACAGTTCAATCAATTAAAGCCAAAGGTACAAAACTTTGCACAGCTATTACAAGAAATTAATATGCAGCTTAATAAAACT
GCAGAAGCTGTTGCTTCTCATGATGAAGAATTATCACGTAATTTCGGTTTGAAATAA

Upstream 100 bases:

>100_bases
AAAGATAAAACGTTTAAAAGTTCAAAATAATACATTATAATATTTTTAGTAAAATTAACCAATACTATTTTGCTCATTAT
GTATTAAAGGGGAAATGAAA

Downstream 100 bases:

>100_bases
AAATTGTCATACTCTATATAACAGGCATTTCAAATGAGCCATACAGCTTATAGTGTATGGCTCATTTGATTGCATGCCCA
ACTTAGCTGGACACACGTTT

Product: WXG domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 98; Mature: 97

Protein sequence:

>98_residues
MAGQIRMSPEELKSKAARYGQGANQIEDILSQLQNLQNELRGEWEGRAFEGFDQQFNQLKPKVQNFAQLLQEINMQLNKT
AEAVASHDEELSRNFGLK

Sequences:

>Translated_98_residues
MAGQIRMSPEELKSKAARYGQGANQIEDILSQLQNLQNELRGEWEGRAFEGFDQQFNQLKPKVQNFAQLLQEINMQLNKT
AEAVASHDEELSRNFGLK
>Mature_97_residues
AGQIRMSPEELKSKAARYGQGANQIEDILSQLQNLQNELRGEWEGRAFEGFDQQFNQLKPKVQNFAQLLQEINMQLNKTA
EAVASHDEELSRNFGLK

Specific function: Virulence factor that is important for the establishment of infection in the host [H]

COG id: COG4842

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ESAT-6 (esx) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010310 [H]

Pfam domain/function: PF06013 WXG100 [H]

EC number: NA

Molecular weight: Translated: 11194; Mature: 11062

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGQIRMSPEELKSKAARYGQGANQIEDILSQLQNLQNELRGEWEGRAFEGFDQQFNQLK
CCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
PKVQNFAQLLQEINMQLNKTAEAVASHDEELSRNFGLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AGQIRMSPEELKSKAARYGQGANQIEDILSQLQNLQNELRGEWEGRAFEGFDQQFNQLK
CCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
PKVQNFAQLLQEINMQLNKTAEAVASHDEELSRNFGLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA