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The map label for this gene is qorA [H]

Identifier: 218234115

GI number: 218234115

Start: 2023573

End: 2024559

Strand: Reverse

Name: qorA [H]

Synonym: BCB4264_A2123

Alternate gene names: 218234115

Gene position: 2024559-2023573 (Counterclockwise)

Preceding gene: 218233939

Following gene: 218235503

Centisome position: 37.36

GC content: 38.91

Gene sequence:

>987_bases
ATGAAAGCTATCGTTGTAACGTCGTTCGGTGGTCCTGAAGTGATGAAATATACAGATTTTGATATACCGGCTATTTCAGA
AGATCAAGTTTTAATTCGCGTAGTTGCTACTAGTGTAAATTTCGCTGATATTAAATCACGTTATGGTAAAAAAGGAAATA
AAGCACTACCTTTTATTCCAGGTATAGATGCCACTGGTATTGTAGAACGTGTCGGTTCTCATGTGAAAAATATTCACCCT
GGACAACGTGTCATTGCTTTTCCTCAAAATGGATCTTACGCAGAATACGTTGTTGCAAATGAAAATCTTACTTTCGTATT
ACCCCATGAAGTTGACTTTCACACTGCAGCCGCTTGTCCGATCGTATCTTTTACAAGCTATAATTTACTCGCAAATGTTG
CAAGGATTCAAAAAGGTGAATCTGTACTCATTCATGCAGCTGCTGGCGGGATTGGTACTACCGCAATTCAATTTGCAAAA
CTATTAGGGGCTAGAACAGTTATCGGTACTATCGGAAGTGAAACGAAAAGAAAAATCGCTTTAGATTCTGGAGCTGATTA
TGTTATTTGTCATCAAACTGAAGATTTTGTAGAGAAAGTCAATGAGCTGACAAACGGAGAAGGAGTGAATATTATTTTGG
ACTCTATTTCTGGAACTGTTTCTGAAAGAAGTTTAAACTGCCTTGCTTTTTACGGTCGCCTCGTTCATTTCGGTAATGCT
AGCGGTGAAATTGGTAACTTTCAAACGAAAGATTTACATGCAAGTTGCCGCTCTATACTCGGTTTTAGCTTTGGAACCAC
ACGAAAAAAGCGTCCTGAACTGCTCCAAGAAACTGCAAATGAAGTTTTCCGTTATTTGCGTGACGGACGTTTACAAATTA
AGGCTACGAAATCTTTTCCACTTCAAGATGCAGGGAAAGCACATGAATGGGTCGAAAGTAGAAAAAGTACAGGGAAAGTA
ATACCAACTGTTCAGTCCTCTTCCTGA

Upstream 100 bases:

>100_bases
CATAAGCTTCACTTATAACCACACATAACTATTATATAATTTTCCAATTTCTGATAAAGATTTAAAATAATTTATATAGT
CAAATTTAGGAGGACATATA

Downstream 100 bases:

>100_bases
AATGAATACTGGAAACAGAGGTGGCATTCATGGGATCACGAATTATGCATGTTATTATCGCTAACGGTATTGCTGAGAAA
CTATCTATTCACGATAAGAC

Product: oxidoreductase, zinc-binding dehydrogenase family

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MKAIVVTSFGGPEVMKYTDFDIPAISEDQVLIRVVATSVNFADIKSRYGKKGNKALPFIPGIDATGIVERVGSHVKNIHP
GQRVIAFPQNGSYAEYVVANENLTFVLPHEVDFHTAAACPIVSFTSYNLLANVARIQKGESVLIHAAAGGIGTTAIQFAK
LLGARTVIGTIGSETKRKIALDSGADYVICHQTEDFVEKVNELTNGEGVNIILDSISGTVSERSLNCLAFYGRLVHFGNA
SGEIGNFQTKDLHASCRSILGFSFGTTRKKRPELLQETANEVFRYLRDGRLQIKATKSFPLQDAGKAHEWVESRKSTGKV
IPTVQSSS

Sequences:

>Translated_328_residues
MKAIVVTSFGGPEVMKYTDFDIPAISEDQVLIRVVATSVNFADIKSRYGKKGNKALPFIPGIDATGIVERVGSHVKNIHP
GQRVIAFPQNGSYAEYVVANENLTFVLPHEVDFHTAAACPIVSFTSYNLLANVARIQKGESVLIHAAAGGIGTTAIQFAK
LLGARTVIGTIGSETKRKIALDSGADYVICHQTEDFVEKVNELTNGEGVNIILDSISGTVSERSLNCLAFYGRLVHFGNA
SGEIGNFQTKDLHASCRSILGFSFGTTRKKRPELLQETANEVFRYLRDGRLQIKATKSFPLQDAGKAHEWVESRKSTGKV
IPTVQSSS
>Mature_328_residues
MKAIVVTSFGGPEVMKYTDFDIPAISEDQVLIRVVATSVNFADIKSRYGKKGNKALPFIPGIDATGIVERVGSHVKNIHP
GQRVIAFPQNGSYAEYVVANENLTFVLPHEVDFHTAAACPIVSFTSYNLLANVARIQKGESVLIHAAAGGIGTTAIQFAK
LLGARTVIGTIGSETKRKIALDSGADYVICHQTEDFVEKVNELTNGEGVNIILDSISGTVSERSLNCLAFYGRLVHFGNA
SGEIGNFQTKDLHASCRSILGFSFGTTRKKRPELLQETANEVFRYLRDGRLQIKATKSFPLQDAGKAHEWVESRKSTGKV
IPTVQSSS

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=325, Percent_Identity=33.5384615384615, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI13236495, Length=325, Percent_Identity=33.5384615384615, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI22538446, Length=328, Percent_Identity=31.0975609756098, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI22538444, Length=328, Percent_Identity=31.0975609756098, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI194239676, Length=325, Percent_Identity=31.0769230769231, Blast_Score=141, Evalue=9e-34,
Organism=Homo sapiens, GI18379349, Length=340, Percent_Identity=27.0588235294118, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI24308257, Length=346, Percent_Identity=26.878612716763, Blast_Score=131, Evalue=8e-31,
Organism=Homo sapiens, GI67078404, Length=323, Percent_Identity=26.625386996904, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI197927207, Length=193, Percent_Identity=30.0518134715026, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI67078406, Length=289, Percent_Identity=27.3356401384083, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI47519420, Length=245, Percent_Identity=30.2040816326531, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI41872631, Length=230, Percent_Identity=30.4347826086957, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI28557745, Length=226, Percent_Identity=28.7610619469027, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1790485, Length=325, Percent_Identity=36.9230769230769, Blast_Score=184, Evalue=7e-48,
Organism=Escherichia coli, GI226510941, Length=329, Percent_Identity=22.7963525835866, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17507255, Length=316, Percent_Identity=31.9620253164557, Blast_Score=136, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71987554, Length=370, Percent_Identity=25.9459459459459, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17536829, Length=289, Percent_Identity=26.9896193771626, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI212642053, Length=312, Percent_Identity=26.6025641025641, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6319520, Length=327, Percent_Identity=32.7217125382263, Blast_Score=149, Evalue=6e-37,
Organism=Drosophila melanogaster, GI24581345, Length=304, Percent_Identity=28.9473684210526, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI221330659, Length=299, Percent_Identity=27.0903010033445, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI19920632, Length=299, Percent_Identity=27.0903010033445, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI45550423, Length=169, Percent_Identity=26.6272189349112, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 35546; Mature: 35546

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS01162 QOR_ZETA_CRYSTAL ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIVVTSFGGPEVMKYTDFDIPAISEDQVLIRVVATSVNFADIKSRYGKKGNKALPFIP
CCEEEEEECCCCCEEEEECCCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCCCCCCCC
GIDATGIVERVGSHVKNIHPGQRVIAFPQNGSYAEYVVANENLTFVLPHEVDFHTAAACP
CCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEECCCEEEEECCCCCCCCHHCCC
IVSFTSYNLLANVARIQKGESVLIHAAAGGIGTTAIQFAKLLGARTVIGTIGSETKRKIA
EEEEHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCHHHEECCCCCCCEEEE
LDSGADYVICHQTEDFVEKVNELTNGEGVNIILDSISGTVSERSLNCLAFYGRLVHFGNA
EECCCCEEEEECCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHEECCC
SGEIGNFQTKDLHASCRSILGFSFGTTRKKRPELLQETANEVFRYLRDGRLQIKATKSFP
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCC
LQDAGKAHEWVESRKSTGKVIPTVQSSS
CCCCCHHHHHHHHHHCCCCEEEEECCCC
>Mature Secondary Structure
MKAIVVTSFGGPEVMKYTDFDIPAISEDQVLIRVVATSVNFADIKSRYGKKGNKALPFIP
CCEEEEEECCCCCEEEEECCCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCCCCCCCC
GIDATGIVERVGSHVKNIHPGQRVIAFPQNGSYAEYVVANENLTFVLPHEVDFHTAAACP
CCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEECCCEEEEECCCCCCCCHHCCC
IVSFTSYNLLANVARIQKGESVLIHAAAGGIGTTAIQFAKLLGARTVIGTIGSETKRKIA
EEEEHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCHHHEECCCCCCCEEEE
LDSGADYVICHQTEDFVEKVNELTNGEGVNIILDSISGTVSERSLNCLAFYGRLVHFGNA
EECCCCEEEEECCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHEECCC
SGEIGNFQTKDLHASCRSILGFSFGTTRKKRPELLQETANEVFRYLRDGRLQIKATKSFP
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCC
LQDAGKAHEWVESRKSTGKVIPTVQSSS
CCCCCHHHHHHHHHHCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]