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The map label for this gene is lspA [H]

Identifier: 218234114

GI number: 218234114

Start: 3916430

End: 3916888

Strand: Reverse

Name: lspA [H]

Synonym: BCB4264_A3994

Alternate gene names: 218234114

Gene position: 3916888-3916430 (Counterclockwise)

Preceding gene: 218234706

Following gene: 218233909

Centisome position: 72.28

GC content: 32.46

Gene sequence:

>459_bases
ATGATATATTATGTAATAGCGTTATTCGTCATTGCTATCGATCAAATATCGAAGTGGTTAATTGTAAAGAACATGGAATT
GGGTACGAGTATTCCGATTATCGACAATGTATTATACATAACATCACATCGAAATAGAGGCGCTGCTTGGGGTATTTTAG
AAAATAAAATGTGGTTCTTCTACATTATTACAGTTGTTTTTGTAGTGTTTATTGTATTTTATATGAAAAAGTATGCGAAA
ACAGACAAGCTTCTAGGTATTTCGTTAGGCCTAATTTTGGGCGGGGCAATGGGTAACTTTATTGATCGTGTATTTAGACA
AGAAGTAGTGGATTTCATTCACGTGTATATTTTCTCGTACAACTATCCAGTATTCAATATAGCTGATTCAGCATTATGTA
TTGGTGTTGTATTAATTATTATTCAAACATTATTAGAAGGCAAGAAAGCGAAGGAGTAA

Upstream 100 bases:

>100_bases
CTTTTTTTAATTTATTTTATTCTTCTATAAAGGTTCATTGTGAAAAGGTAGCAGCTATGCTAAAATTTTGAGGTACACTG
TCTTTGTGGGGGAAATGAAA

Downstream 100 bases:

>100_bases
TTGAATGAGTGAAGTAGTACAAGTAACAGTTGCAGCAGAGCAAAAAAACGAGCGAATTGATAAATTCGTTACAGGGATAA
ATAACGAATGGTCACGTACG

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MIYYVIALFVIAIDQISKWLIVKNMELGTSIPIIDNVLYITSHRNRGAAWGILENKMWFFYIITVVFVVFIVFYMKKYAK
TDKLLGISLGLILGGAMGNFIDRVFRQEVVDFIHVYIFSYNYPVFNIADSALCIGVVLIIIQTLLEGKKAKE

Sequences:

>Translated_152_residues
MIYYVIALFVIAIDQISKWLIVKNMELGTSIPIIDNVLYITSHRNRGAAWGILENKMWFFYIITVVFVVFIVFYMKKYAK
TDKLLGISLGLILGGAMGNFIDRVFRQEVVDFIHVYIFSYNYPVFNIADSALCIGVVLIIIQTLLEGKKAKE
>Mature_152_residues
MIYYVIALFVIAIDQISKWLIVKNMELGTSIPIIDNVLYITSHRNRGAAWGILENKMWFFYIITVVFVVFIVFYMKKYAK
TDKLLGISLGLILGGAMGNFIDRVFRQEVVDFIHVYIFSYNYPVFNIADSALCIGVVLIIIQTLLEGKKAKE

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=147, Percent_Identity=36.0544217687075, Blast_Score=97, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 17442; Mature: 17442

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYYVIALFVIAIDQISKWLIVKNMELGTSIPIIDNVLYITSHRNRGAAWGILENKMWFF
CHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHEEEEECCCCCCCCCCHHHCCHHHH
YIITVVFVVFIVFYMKKYAKTDKLLGISLGLILGGAMGNFIDRVFRQEVVDFIHVYIFSY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NYPVFNIADSALCIGVVLIIIQTLLEGKKAKE
CCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MIYYVIALFVIAIDQISKWLIVKNMELGTSIPIIDNVLYITSHRNRGAAWGILENKMWFF
CHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHEEEEECCCCCCCCCCHHHCCHHHH
YIITVVFVVFIVFYMKKYAKTDKLLGISLGLILGGAMGNFIDRVFRQEVVDFIHVYIFSY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NYPVFNIADSALCIGVVLIIIQTLLEGKKAKE
CCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA