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The map label for this gene is ywcA [H]

Identifier: 218234094

GI number: 218234094

Start: 1595410

End: 1596960

Strand: Direct

Name: ywcA [H]

Synonym: BCB4264_A1672

Alternate gene names: 218234094

Gene position: 1595410-1596960 (Clockwise)

Preceding gene: 218233380

Following gene: 218232230

Centisome position: 29.44

GC content: 37.59

Gene sequence:

>1551_bases
TTGAATACTACTGCATTTGCACTATTTTTAATTATTGTTCTTGGTACGCTCGTCATAACCTATTTTGCATCGAAAAAAAC
GAAAAATGCGAGTGAATTTTATACGGCTGGAGGGGGATTAACTGGTTGGCAAAATGGTCTGGCCATTGCTGGAGATTACA
TGTCTGCTGCTTCATTTCTCGGTATAGCTGGAGCAATCGCATTAACTGGGTTTGATGGATTCTTTTATAGTATCGGTTTT
TTAGTTGCTTATCTAGTTGTACTATATCTTGTTGCAGAACCGCTTAGAAATTTAGGAAAGTACACTTTGGCGGATATGAT
TGCAGCACGCTTTGATGCGAAAAAAGTTCGCGGAGTTGCAGCTCTTAATACGATGACGATTTCTATTTTTTATATGATTG
CACAATTAGTTGGCGCGGGTGCACTTATTAAATTATTATTAGGGATTGAATATACGACATCTGTATTAATCGTTGGAACA
CTTATGACGGTGTATGTTATTTTTGGTGGTATGACAGCAACGAGCTGGGTACAAATTGTAAAGGCTGTATTACTTATGGC
TGGTACTTTTATTATTTCTGTTATCGTTTTCGCAAAATTCAACTTCAGTGTGACTGAAATGTTCGCTCAAATGAAAACAG
CTACACCTTTAAAAGATTCATTTTTAAATCCAGGTGTAAAGTATAAGGATGGTCTTGATACACTTTCTTTAAATTTAGGA
CTAGTACTTGGTACAGCTGGATTACCACATATACTTGTCCGCTTTTTTACAGTACGTGATGCAAAAACTGCACGACAATC
TGTCGTATATGCGACGTGGTTAATTGGTGCATTTTATATTATGACGATTTTCTTAGGATTTGGTGCGGCAGCGTTTGTAG
GAAATGAAGCTATTATTAAAGCGAACCCAGCTGGTAATATGGCGGCACCTTTATTAGCCAAAGCGTTAGGTGGAGACTTC
TTATTTGCTTTCGTATCAGCAATTGCTTTTGCAACGATTTTGGCTGTAGTGGCAGGTCTTGTATTAACAGCAGCATCAGC
ATTCGCTCATGATTTTTATAATGAAATCATTCGCAGAGGGAAATCAACAGAAAAAGAGCAAGTATCCATGGCTCGTTATG
CATCTATTGGAGTAGCGATACTATCTATCATACTTGCATTATTTGCCCAAACATTAAACGTAGCATTTTTAGTATCATTA
GCATTTGCAGTTGCAGCGAGTGCAAATCTACCAGTAATTTTATTTACAATATATTGGAAGCGTTTTAATACAACGGGTGC
TATTTCGGGTATGATTGTAGGTCTCGTATCAGCAATTGTTCTCGTAGCGTTGAGTCCGAATGTTTGGAACCCTGTAGCTG
GAAAAGCTATTTTTGTTGGGGAAGCGTTATTCCCATATACGACACCAGGAATTATTTCAATTCCACTCGGATTTCTTGCA
GCATATTTAGGAACGGTTTTATCTAGTAAGAAAGAAGATGAAGCGAAATTTGATGAAATTCTAGTGAAATCTAATACTGG
TCATGGCATTAGCGATGCGTCTTCACATTAA

Upstream 100 bases:

>100_bases
TGACATGGGCACTCTGTATGATTTATAGCAAAAAAGCAGAATCATTTGATGAAATCTCCCGAAAAATTCTGCAAGATATG
CAAAAAGGGAGGGGCTGAAC

Downstream 100 bases:

>100_bases
ATAAAAGAGGAGCTTTTCGATAGATAAGAAAAGCTCTTTTTTCTTTTGTCATTTTCTTGTAAATATTACTGATTTGTAAG
TAGGATTTGTCTTAATTTTG

Product: sodium/solute symporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MNTTAFALFLIIVLGTLVITYFASKKTKNASEFYTAGGGLTGWQNGLAIAGDYMSAASFLGIAGAIALTGFDGFFYSIGF
LVAYLVVLYLVAEPLRNLGKYTLADMIAARFDAKKVRGVAALNTMTISIFYMIAQLVGAGALIKLLLGIEYTTSVLIVGT
LMTVYVIFGGMTATSWVQIVKAVLLMAGTFIISVIVFAKFNFSVTEMFAQMKTATPLKDSFLNPGVKYKDGLDTLSLNLG
LVLGTAGLPHILVRFFTVRDAKTARQSVVYATWLIGAFYIMTIFLGFGAAAFVGNEAIIKANPAGNMAAPLLAKALGGDF
LFAFVSAIAFATILAVVAGLVLTAASAFAHDFYNEIIRRGKSTEKEQVSMARYASIGVAILSIILALFAQTLNVAFLVSL
AFAVAASANLPVILFTIYWKRFNTTGAISGMIVGLVSAIVLVALSPNVWNPVAGKAIFVGEALFPYTTPGIISIPLGFLA
AYLGTVLSSKKEDEAKFDEILVKSNTGHGISDASSH

Sequences:

>Translated_516_residues
MNTTAFALFLIIVLGTLVITYFASKKTKNASEFYTAGGGLTGWQNGLAIAGDYMSAASFLGIAGAIALTGFDGFFYSIGF
LVAYLVVLYLVAEPLRNLGKYTLADMIAARFDAKKVRGVAALNTMTISIFYMIAQLVGAGALIKLLLGIEYTTSVLIVGT
LMTVYVIFGGMTATSWVQIVKAVLLMAGTFIISVIVFAKFNFSVTEMFAQMKTATPLKDSFLNPGVKYKDGLDTLSLNLG
LVLGTAGLPHILVRFFTVRDAKTARQSVVYATWLIGAFYIMTIFLGFGAAAFVGNEAIIKANPAGNMAAPLLAKALGGDF
LFAFVSAIAFATILAVVAGLVLTAASAFAHDFYNEIIRRGKSTEKEQVSMARYASIGVAILSIILALFAQTLNVAFLVSL
AFAVAASANLPVILFTIYWKRFNTTGAISGMIVGLVSAIVLVALSPNVWNPVAGKAIFVGEALFPYTTPGIISIPLGFLA
AYLGTVLSSKKEDEAKFDEILVKSNTGHGISDASSH
>Mature_516_residues
MNTTAFALFLIIVLGTLVITYFASKKTKNASEFYTAGGGLTGWQNGLAIAGDYMSAASFLGIAGAIALTGFDGFFYSIGF
LVAYLVVLYLVAEPLRNLGKYTLADMIAARFDAKKVRGVAALNTMTISIFYMIAQLVGAGALIKLLLGIEYTTSVLIVGT
LMTVYVIFGGMTATSWVQIVKAVLLMAGTFIISVIVFAKFNFSVTEMFAQMKTATPLKDSFLNPGVKYKDGLDTLSLNLG
LVLGTAGLPHILVRFFTVRDAKTARQSVVYATWLIGAFYIMTIFLGFGAAAFVGNEAIIKANPAGNMAAPLLAKALGGDF
LFAFVSAIAFATILAVVAGLVLTAASAFAHDFYNEIIRRGKSTEKEQVSMARYASIGVAILSIILALFAQTLNVAFLVSL
AFAVAASANLPVILFTIYWKRFNTTGAISGMIVGLVSAIVLVALSPNVWNPVAGKAIFVGEALFPYTTPGIISIPLGFLA
AYLGTVLSSKKEDEAKFDEILVKSNTGHGISDASSH

Specific function: Unknown

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=454, Percent_Identity=25.3303964757709, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI14140236, Length=509, Percent_Identity=19.056974459725, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI1790503, Length=524, Percent_Identity=45.6106870229008, Blast_Score=454, Evalue=1e-129,
Organism=Escherichia coli, GI1787251, Length=461, Percent_Identity=26.8980477223427, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI87082237, Length=458, Percent_Identity=24.4541484716157, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24648033, Length=390, Percent_Identity=24.8717948717949, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21356865, Length=390, Percent_Identity=24.8717948717949, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 54651; Mature: 54651

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS00457 NA_SOLUT_SYMP_2 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHCCCCCHHHHHHHHHEECCCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHCCCCCHHHHHHHHHEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]