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The map label for this gene is ygbD [C]

Identifier: 218233991

GI number: 218233991

Start: 1266599

End: 1267933

Strand: Direct

Name: ygbD [C]

Synonym: BCB4264_A1307

Alternate gene names: 218233991

Gene position: 1266599-1267933 (Clockwise)

Preceding gene: 218233477

Following gene: 218234747

Centisome position: 23.37

GC content: 38.73

Gene sequence:

>1335_bases
GTGAACTATGTCATTATTGGCGGAGATGCAGCTGGTATGAGTGCAGCGATGCAAATTGTTAGAAACGATGAAAATGCAAA
TGTTGTAACTTTAGAAAAAGGTGAAATTTATTCATACGCTCAGTGTGGATTACCGTATGTCATTAGTGGTGCTATCGCTT
CAACTGAAAAGTTAATCGCGCGTAACGTAAAGACGTTTCGTGAGAAATATGGAATTGATGCGAAAGTGCGTCATGAAGTA
ACGAAAGTAGATACGGAAAAGAAAATGGTGTACGCAGAGCATACGAAGACGAAAGATGTCTTTGAATTTCCGTACGATCG
ATTATTAATTGCGACTGGAGTGCGTCCTGTTATGCCAGAATGGGAAGGACGGGAATTACAAGGCGTTCATCTTTTAAAAA
CAATTCCTGATGCTGAGCGCATATTAAAAACGCTAGAAACGAATAAAGTTGAAGATGTAACGATTATTGGCGGTGGTGCC
ATTGGACTTGAGATGGCAGAAACATTCGTCGAACTTGGTAAGAAAGTAAGAATGATTGAGCGAAATGATCATATCGGTAC
GATTTATGATGCAGATATGGCAGAGTACATACATAAAGAAGCAGATAAGCATCATATTGAAATTTTAACGAATGAAAATG
TAAAAGCATTTAAAGGAAATGAACGAGTAGAAGCAATCGAAACGGATAAAGGTACGTATAAAGCAGATCTTGTTTTAGTG
TCGGTTGGAGTGAAGCCAAATACTGATTTTCTTGAAGGGACAAATATACGTAAGAATCATAAAGGAGCAATCGAAGTAAA
TGCATATATGCAAACAAATGTGCAAGACGTATATGCAGCTGGTGATTGCGCAACACATTACCACGTTATAAAGGAAATTC
ATGATCATATCCCGCTCGGAACGACTGCCAATAAACAAGGGCGACTTGCTGGACTGAATATGCTTGATAAACGAAGAGCC
TTTAAAGGTACGTTAGGTACAGGTATTATTAAATTTATGGATTTGACGCTTGCAAGAACAGGATTAAATGAAAAAGAAGC
GAAAGGGCTACACATCCCGTATAAAACAGTCAAAGTAGATTCCACTAATATGGCGGGCTATTATCCAAATGCGAAACCAC
TTTACTTGAAATTACTATACCGTTCCGATACGAAACAATTATTAGGCGGGCAAGTAATTGGAGAAGAAGGCGTAGATAAA
CGGATTGATGTGATCGCGATGGCACTTTTCAATAAAATGAGCATTCATGATTTAGAAGATGTAGACTTAAGTTATGCACC
ACCATATAACAGCGTTTGGGATCCAATACAGCAAGCGGCAAGGAGAGCAGAATAG

Upstream 100 bases:

>100_bases
AATTTGAAGATGAAATTCTCTTTCTTTACAATGGAAGTAGGTGTTATTTCTATAAAATATGGAAAACGTAAAGAGTATGT
AAAAAAGAAGGAGTGGTAAA

Downstream 100 bases:

>100_bases
CACTTTTTAAGTGCTATTTTTTTCGTTAAAGGGGAATAAGCCTTTTTGCCGAATAAAAAAGGGGGAAATAATTACAAATA
GGGAAGAGGGATCATTAAAA

Product: pyridine nucleotide-disulfide oxidoreductase, class I

Products: NA

Alternate protein names: CoA-disulfide reductase; CoADR [H]

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MNYVIIGGDAAGMSAAMQIVRNDENANVVTLEKGEIYSYAQCGLPYVISGAIASTEKLIARNVKTFREKYGIDAKVRHEV
TKVDTEKKMVYAEHTKTKDVFEFPYDRLLIATGVRPVMPEWEGRELQGVHLLKTIPDAERILKTLETNKVEDVTIIGGGA
IGLEMAETFVELGKKVRMIERNDHIGTIYDADMAEYIHKEADKHHIEILTNENVKAFKGNERVEAIETDKGTYKADLVLV
SVGVKPNTDFLEGTNIRKNHKGAIEVNAYMQTNVQDVYAAGDCATHYHVIKEIHDHIPLGTTANKQGRLAGLNMLDKRRA
FKGTLGTGIIKFMDLTLARTGLNEKEAKGLHIPYKTVKVDSTNMAGYYPNAKPLYLKLLYRSDTKQLLGGQVIGEEGVDK
RIDVIAMALFNKMSIHDLEDVDLSYAPPYNSVWDPIQQAARRAE

Sequences:

>Translated_444_residues
MNYVIIGGDAAGMSAAMQIVRNDENANVVTLEKGEIYSYAQCGLPYVISGAIASTEKLIARNVKTFREKYGIDAKVRHEV
TKVDTEKKMVYAEHTKTKDVFEFPYDRLLIATGVRPVMPEWEGRELQGVHLLKTIPDAERILKTLETNKVEDVTIIGGGA
IGLEMAETFVELGKKVRMIERNDHIGTIYDADMAEYIHKEADKHHIEILTNENVKAFKGNERVEAIETDKGTYKADLVLV
SVGVKPNTDFLEGTNIRKNHKGAIEVNAYMQTNVQDVYAAGDCATHYHVIKEIHDHIPLGTTANKQGRLAGLNMLDKRRA
FKGTLGTGIIKFMDLTLARTGLNEKEAKGLHIPYKTVKVDSTNMAGYYPNAKPLYLKLLYRSDTKQLLGGQVIGEEGVDK
RIDVIAMALFNKMSIHDLEDVDLSYAPPYNSVWDPIQQAARRAE
>Mature_444_residues
MNYVIIGGDAAGMSAAMQIVRNDENANVVTLEKGEIYSYAQCGLPYVISGAIASTEKLIARNVKTFREKYGIDAKVRHEV
TKVDTEKKMVYAEHTKTKDVFEFPYDRLLIATGVRPVMPEWEGRELQGVHLLKTIPDAERILKTLETNKVEDVTIIGGGA
IGLEMAETFVELGKKVRMIERNDHIGTIYDADMAEYIHKEADKHHIEILTNENVKAFKGNERVEAIETDKGTYKADLVLV
SVGVKPNTDFLEGTNIRKNHKGAIEVNAYMQTNVQDVYAAGDCATHYHVIKEIHDHIPLGTTANKQGRLAGLNMLDKRRA
FKGTLGTGIIKFMDLTLARTGLNEKEAKGLHIPYKTVKVDSTNMAGYYPNAKPLYLKLLYRSDTKQLLGGQVIGEEGVDK
RIDVIAMALFNKMSIHDLEDVDLSYAPPYNSVWDPIQQAARRAE

Specific function: Unknown

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=325, Percent_Identity=28, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI226437568, Length=325, Percent_Identity=28, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI65787454, Length=325, Percent_Identity=28, Blast_Score=112, Evalue=7e-25,
Organism=Escherichia coli, GI1789065, Length=285, Percent_Identity=24.2105263157895, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786307, Length=437, Percent_Identity=24.2562929061785, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789765, Length=340, Percent_Identity=23.5294117647059, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082354, Length=300, Percent_Identity=25, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789915, Length=318, Percent_Identity=24.2138364779874, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17559934, Length=300, Percent_Identity=24.3333333333333, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24585130, Length=322, Percent_Identity=26.3975155279503, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24639257, Length=323, Percent_Identity=24.7678018575851, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281359715, Length=323, Percent_Identity=24.7678018575851, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281359713, Length=323, Percent_Identity=24.7678018575851, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24639250, Length=323, Percent_Identity=24.7678018575851, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI18543267, Length=323, Percent_Identity=24.7678018575851, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24639252, Length=323, Percent_Identity=24.7678018575851, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24581020, Length=361, Percent_Identity=24.3767313019391, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28573993, Length=361, Percent_Identity=24.3767313019391, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21358499, Length=215, Percent_Identity=32.093023255814, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017758
- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.8.1.14 [H]

Molecular weight: Translated: 49569; Mature: 49569

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYVIIGGDAAGMSAAMQIVRNDENANVVTLEKGEIYSYAQCGLPYVISGAIASTEKLIA
CCEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCEEEHHHCCCCEEEECHHHHHHHHHH
RNVKTFREKYGIDAKVRHEVTKVDTEKKMVYAEHTKTKDVFEFPYDRLLIATGVRPVMPE
HHHHHHHHHHCCCHHHHHHHHHCCCCHHEEEEECCCCCHHHHCCHHHEEEECCCCCCCCC
WEGRELQGVHLLKTIPDAERILKTLETNKVEDVTIIGGGAIGLEMAETFVELGKKVRMIE
CCCCCCCCEEHHHHCCCHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHEEEEE
RNDHIGTIYDADMAEYIHKEADKHHIEILTNENVKAFKGNERVEAIETDKGTYKADLVLV
CCCCEEEEECCHHHHHHHHCCCCEEEEEEECCCEEEECCCCCEEEEECCCCCEEEEEEEE
SVGVKPNTDFLEGTNIRKNHKGAIEVNAYMQTNVQDVYAAGDCATHYHVIKEIHDHIPLG
EECCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCHHHEECCCHHHHHHHHHHHHHCCCCC
TTANKQGRLAGLNMLDKRRAFKGTLGTGIIKFMDLTLARTGLNEKEAKGLHIPYKTVKVD
CCCCCCCCEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCEEEEEEC
STNMAGYYPNAKPLYLKLLYRSDTKQLLGGQVIGEEGVDKRIDVIAMALFNKMSIHDLED
CCCCCCCCCCCCCEEEEEEECCCHHHHHCCEEECCCCCCHHHHHHHHHHHCCCCCCCCCC
VDLSYAPPYNSVWDPIQQAARRAE
CCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNYVIIGGDAAGMSAAMQIVRNDENANVVTLEKGEIYSYAQCGLPYVISGAIASTEKLIA
CCEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCEEEHHHCCCCEEEECHHHHHHHHHH
RNVKTFREKYGIDAKVRHEVTKVDTEKKMVYAEHTKTKDVFEFPYDRLLIATGVRPVMPE
HHHHHHHHHHCCCHHHHHHHHHCCCCHHEEEEECCCCCHHHHCCHHHEEEECCCCCCCCC
WEGRELQGVHLLKTIPDAERILKTLETNKVEDVTIIGGGAIGLEMAETFVELGKKVRMIE
CCCCCCCCEEHHHHCCCHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHEEEEE
RNDHIGTIYDADMAEYIHKEADKHHIEILTNENVKAFKGNERVEAIETDKGTYKADLVLV
CCCCEEEEECCHHHHHHHHCCCCEEEEEEECCCEEEECCCCCEEEEECCCCCEEEEEEEE
SVGVKPNTDFLEGTNIRKNHKGAIEVNAYMQTNVQDVYAAGDCATHYHVIKEIHDHIPLG
EECCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCHHHEECCCHHHHHHHHHHHHHCCCCC
TTANKQGRLAGLNMLDKRRAFKGTLGTGIIKFMDLTLARTGLNEKEAKGLHIPYKTVKVD
CCCCCCCCEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCEEEEEEC
STNMAGYYPNAKPLYLKLLYRSDTKQLLGGQVIGEEGVDKRIDVIAMALFNKMSIHDLED
CCCCCCCCCCCCCEEEEEEECCCHHHHHCCEEECCCCCCHHHHHHHHHHHCCCCCCCCCC
VDLSYAPPYNSVWDPIQQAARRAE
CCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA