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The map label for this gene is dppE [H]

Identifier: 218233978

GI number: 218233978

Start: 2746671

End: 2748293

Strand: Reverse

Name: dppE [H]

Synonym: BCB4264_A2861

Alternate gene names: 218233978

Gene position: 2748293-2746671 (Counterclockwise)

Preceding gene: 218231988

Following gene: 218235309

Centisome position: 50.72

GC content: 33.39

Gene sequence:

>1623_bases
ATGAAAAAAGTTATTCGTTACTCATTAGTTAGTACGCTATTAGTTTCTTCATTTTTAGTTGGTTGCGCAAAAGAAAAAAC
TGCAACAAAGCCGAAAGATGAGAAGAAAGTATTACAGTTACTAGAAACAGGTGAAATTCCGTCGTTAAATTCAGGGAAAG
TAACAGATGCAGTCTCGTTTAACGTTTTGAATAACGTAATGGAAGGACTATTCCGTCTATCGAAAAATGATGAAGTAATT
GAAGCCGGTGCACAAAAATATGAAGTGAGTAAAGATGGAAAAACATATACATTCCAATTGCGTGATGCGAAATGGTCTAA
CGGAGAGCCAGTAACCGCTCATGATTACGTATACGCTTGGAAGCAATTGATAAATCCAGATACTGCTTCTCAATATGCAT
ACATTGCGTACGATGTAAAAAATGCTGAGAAGATAAATAAAAAACAACTAGGTCTAGATGAATTAGGAGTAAAAGCCAAG
GATGATAAAACATTCGTCGTAGAGCTAGAACATCCTGTACCGTATTTTACGAAATTATTAATTTTACCATCCTTCTATCC
AATTAACGAAAAATATGCGAAAGAGCAAGGTGATAAATATGGATTAGAAGCAAATGAAGCGGTATATAATGGACCGTTTA
CATTATCAGAGTGGAAGCATGAAGCTAGCTTTACAATGAAGAAAAACGATAAGTATTGGGATAAAAAAGAAGTGAAGTTA
GATGAAGTAAACTATCAAATTGTAAAAGAAATTTCAACTGCGGTAAATTTATATGAAACAGATAAAGTTGATAGAGCTGT
TATTTCTACAGAATTCGTAGATAAATATAAAAATAATAAAGAGTTAAAACAATATACAGATCCAGTTATGTACTTCTTCC
GATTTAATGAAAATGTACCGATTCTTAAAAATAAAAATGCACGTCTTGCGCTAAGTACAGTTTTTGATAAGAAGGGACTC
GCAGATTCATTTTTAAATGATGGATCGGTTGCAGCAAACTATTACGTACCAAAAGGATTTTTAAAGGGGCCAGATAAAAA
AGATTTTAGAAGTACGGCAGGTGAGTTTAATAAAACTGATGTAAAAAAAGCGAAAGAATATTGGGAAAAGGCAAAGCAAG
AAACAGGTACAGATGAAGTGACGTTAGAACTATTAAATTATGACTTGGAAAACTTTAAAAAAGTTGGAGAGTACATTAAA
GAGCAGCTTGAGAAAAACTTACCAGGATTAAAAGTGAATGTGAAATTACAACCACATACGCAAAAATTAGCACTTGAGAA
GAAGAAAGAATATGAAATGTCGTTATCACGCTGGTTACCGGATTATCCAGATCCAATGACTTACTTAGAAGTATTCCTTT
CTGGAAGCAGTGTTAATAATACAGAATATGCAAACCCAGAATATGATGCGTTAATTAAGAAGATTAAAACAGAATTAGGT
AATGATGAAAAGGCTCGCTGGAAAGCAATGCAAGATGCTGAAAAAATGCTACTGGATGATGCAGTAATTGCACCGGTATT
CCAGCGTGGATTATCTTACTTACAAAAACCATATGTGAAAGATTTATATGTACATCAATTTGGTCCAGCTACAAGTTTAA
AATGGGCAGATGTACAAAAATAA

Upstream 100 bases:

>100_bases
AAAGGTCGGTAGAGATTATATCGCTAAATACACCAGGATATATAGAAGAATACGCTGGTGCTCGTCGTTACTTACCTTAA
AAATAGAAGGGGGTTTTTAA

Downstream 100 bases:

>100_bases
AAGAATGGAGAAACAGACTTCATGTATGTGATAGTCTGTTTTTCTTATTTAAAGTTAGAAAAATAGTTCATGGTATAATT
TATTAGTCTGTAAACAGTAT

Product: putative oligopeptide ABC transporter, oligopeptide-binding protein

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 540; Mature: 540

Protein sequence:

>540_residues
MKKVIRYSLVSTLLVSSFLVGCAKEKTATKPKDEKKVLQLLETGEIPSLNSGKVTDAVSFNVLNNVMEGLFRLSKNDEVI
EAGAQKYEVSKDGKTYTFQLRDAKWSNGEPVTAHDYVYAWKQLINPDTASQYAYIAYDVKNAEKINKKQLGLDELGVKAK
DDKTFVVELEHPVPYFTKLLILPSFYPINEKYAKEQGDKYGLEANEAVYNGPFTLSEWKHEASFTMKKNDKYWDKKEVKL
DEVNYQIVKEISTAVNLYETDKVDRAVISTEFVDKYKNNKELKQYTDPVMYFFRFNENVPILKNKNARLALSTVFDKKGL
ADSFLNDGSVAANYYVPKGFLKGPDKKDFRSTAGEFNKTDVKKAKEYWEKAKQETGTDEVTLELLNYDLENFKKVGEYIK
EQLEKNLPGLKVNVKLQPHTQKLALEKKKEYEMSLSRWLPDYPDPMTYLEVFLSGSSVNNTEYANPEYDALIKKIKTELG
NDEKARWKAMQDAEKMLLDDAVIAPVFQRGLSYLQKPYVKDLYVHQFGPATSLKWADVQK

Sequences:

>Translated_540_residues
MKKVIRYSLVSTLLVSSFLVGCAKEKTATKPKDEKKVLQLLETGEIPSLNSGKVTDAVSFNVLNNVMEGLFRLSKNDEVI
EAGAQKYEVSKDGKTYTFQLRDAKWSNGEPVTAHDYVYAWKQLINPDTASQYAYIAYDVKNAEKINKKQLGLDELGVKAK
DDKTFVVELEHPVPYFTKLLILPSFYPINEKYAKEQGDKYGLEANEAVYNGPFTLSEWKHEASFTMKKNDKYWDKKEVKL
DEVNYQIVKEISTAVNLYETDKVDRAVISTEFVDKYKNNKELKQYTDPVMYFFRFNENVPILKNKNARLALSTVFDKKGL
ADSFLNDGSVAANYYVPKGFLKGPDKKDFRSTAGEFNKTDVKKAKEYWEKAKQETGTDEVTLELLNYDLENFKKVGEYIK
EQLEKNLPGLKVNVKLQPHTQKLALEKKKEYEMSLSRWLPDYPDPMTYLEVFLSGSSVNNTEYANPEYDALIKKIKTELG
NDEKARWKAMQDAEKMLLDDAVIAPVFQRGLSYLQKPYVKDLYVHQFGPATSLKWADVQK
>Mature_540_residues
MKKVIRYSLVSTLLVSSFLVGCAKEKTATKPKDEKKVLQLLETGEIPSLNSGKVTDAVSFNVLNNVMEGLFRLSKNDEVI
EAGAQKYEVSKDGKTYTFQLRDAKWSNGEPVTAHDYVYAWKQLINPDTASQYAYIAYDVKNAEKINKKQLGLDELGVKAK
DDKTFVVELEHPVPYFTKLLILPSFYPINEKYAKEQGDKYGLEANEAVYNGPFTLSEWKHEASFTMKKNDKYWDKKEVKL
DEVNYQIVKEISTAVNLYETDKVDRAVISTEFVDKYKNNKELKQYTDPVMYFFRFNENVPILKNKNARLALSTVFDKKGL
ADSFLNDGSVAANYYVPKGFLKGPDKKDFRSTAGEFNKTDVKKAKEYWEKAKQETGTDEVTLELLNYDLENFKKVGEYIK
EQLEKNLPGLKVNVKLQPHTQKLALEKKKEYEMSLSRWLPDYPDPMTYLEVFLSGSSVNNTEYANPEYDALIKKIKTELG
NDEKARWKAMQDAEKMLLDDAVIAPVFQRGLSYLQKPYVKDLYVHQFGPATSLKWADVQK

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787495, Length=534, Percent_Identity=29.4007490636704, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI87081878, Length=535, Percent_Identity=29.5327102803738, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1789397, Length=514, Percent_Identity=28.0155642023346, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1787762, Length=439, Percent_Identity=23.0068337129841, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789966, Length=479, Percent_Identity=22.7557411273486, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2360 Molecules/Cell In: Stationary-Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 62024; Mature: 62024

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVIRYSLVSTLLVSSFLVGCAKEKTATKPKDEKKVLQLLETGEIPSLNSGKVTDAVSF
CCHHHHHHHHHHHHHHHHHHHHHCHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHH
NVLNNVMEGLFRLSKNDEVIEAGAQKYEVSKDGKTYTFQLRDAKWSNGEPVTAHDYVYAW
HHHHHHHHHHHHCCCCCHHHHHCCHHEEECCCCCEEEEEEECCCCCCCCCCCHHHHHHHH
KQLINPDTASQYAYIAYDVKNAEKINKKQLGLDELGVKAKDDKTFVVELEHPVPYFTKLL
HHHCCCCCCCCEEEEEEECCCHHHHHHHHCCHHHHCCCCCCCCEEEEEECCCCHHHHHHH
ILPSFYPINEKYAKEQGDKYGLEANEAVYNGPFTLSEWKHEASFTMKKNDKYWDKKEVKL
HHCCCCCCCHHHHHHCCCCCCCCCCCEEECCCCCHHHHCCCCCEEECCCCCCCCCCCCCH
DEVNYQIVKEISTAVNLYETDKVDRAVISTEFVDKYKNNKELKQYTDPVMYFFRFNENVP
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEEECCCCC
ILKNKNARLALSTVFDKKGLADSFLNDGSVAANYYVPKGFLKGPDKKDFRSTAGEFNKTD
EEECCCCEEEEEEHHHHCCCHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCCHHH
VKKAKEYWEKAKQETGTDEVTLELLNYDLENFKKVGEYIKEQLEKNLPGLKVNVKLQPHT
HHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCH
QKLALEKKKEYEMSLSRWLPDYPDPMTYLEVFLSGSSVNNTEYANPEYDALIKKIKTELG
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHC
NDEKARWKAMQDAEKMLLDDAVIAPVFQRGLSYLQKPYVKDLYVHQFGPATSLKWADVQK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKKVIRYSLVSTLLVSSFLVGCAKEKTATKPKDEKKVLQLLETGEIPSLNSGKVTDAVSF
CCHHHHHHHHHHHHHHHHHHHHHCHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHH
NVLNNVMEGLFRLSKNDEVIEAGAQKYEVSKDGKTYTFQLRDAKWSNGEPVTAHDYVYAW
HHHHHHHHHHHHCCCCCHHHHHCCHHEEECCCCCEEEEEEECCCCCCCCCCCHHHHHHHH
KQLINPDTASQYAYIAYDVKNAEKINKKQLGLDELGVKAKDDKTFVVELEHPVPYFTKLL
HHHCCCCCCCCEEEEEEECCCHHHHHHHHCCHHHHCCCCCCCCEEEEEECCCCHHHHHHH
ILPSFYPINEKYAKEQGDKYGLEANEAVYNGPFTLSEWKHEASFTMKKNDKYWDKKEVKL
HHCCCCCCCHHHHHHCCCCCCCCCCCEEECCCCCHHHHCCCCCEEECCCCCCCCCCCCCH
DEVNYQIVKEISTAVNLYETDKVDRAVISTEFVDKYKNNKELKQYTDPVMYFFRFNENVP
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEEECCCCC
ILKNKNARLALSTVFDKKGLADSFLNDGSVAANYYVPKGFLKGPDKKDFRSTAGEFNKTD
EEECCCCEEEEEEHHHHCCCHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCCHHH
VKKAKEYWEKAKQETGTDEVTLELLNYDLENFKKVGEYIKEQLEKNLPGLKVNVKLQPHT
HHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCH
QKLALEKKKEYEMSLSRWLPDYPDPMTYLEVFLSGSSVNNTEYANPEYDALIKKIKTELG
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHC
NDEKARWKAMQDAEKMLLDDAVIAPVFQRGLSYLQKPYVKDLYVHQFGPATSLKWADVQK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]