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The map label for this gene is mecA2 [H]

Identifier: 218233838

GI number: 218233838

Start: 1478439

End: 1479047

Strand: Direct

Name: mecA2 [H]

Synonym: BCB4264_A1545

Alternate gene names: 218233838

Gene position: 1478439-1479047 (Clockwise)

Preceding gene: 218234619

Following gene: 218233867

Centisome position: 27.28

GC content: 36.12

Gene sequence:

>609_bases
ATGAGGCTGGAACGATTAAATTACAATAAGATAAAAATTTTTCTAACATTTGATGATTTATCTGAACGAGGATTAACGAA
AGAAGATTTATGGAGAAATGCACCGAAAGTACAGCAATTATTTCGTGATATGATGCAAGAAGCAAATAAGGAATTAGGGT
TTGAAGCAGATGGTCCGATTGCAGTTGAAGTGTTTTCTCTACAAGCACAAGGGATGGTTGTAATTGTAACGAAAGAAAAT
CAAGAAATGGATACAGATGATGAGTTCCGTGACGAGTTTATTGAAATGCAAGTGACTCTAGATGAAAGTGAGCATATATT
ATATGAGTTTGCTACGCTAGATGACGTAATTAACCTGTCGAATCGCTTATATAACCTTGGTGTAACTGGCGGAAAGCTAT
ATACGTGGGATGAGCGCTTCTATCTTTGGGTGGAAGAAGAGGAACAAATTCAATTGTTAAAGGCGGATTTTATAGCTATT
TTAGCGGAATACGGTAATCCGTCTACAGCAACCATTTATCGCATCATGGAGTACGGTAAAGAATTAATGGATGTTAACGC
GATAGAACAAATACACAATTACTTTGTGAAAAAACAAAACCTCAGCTAA

Upstream 100 bases:

>100_bases
GATGGTTAAAAATGTCGGAATAGTTGTTCGAAAAGAACCATCTATTTTCTATTTCATATAATAAAAATTAGATGCATTGG
TTACGTAGGGAGGGTATGAG

Downstream 100 bases:

>100_bases
TACAACATAGCTGAGGTTTTGTTTTTATTTGGAGAAGGGAAGGGATGATTGTAAATACTCGAACATACTTTTTGAAAATA
AAATATGCAGTTTTATGGGA

Product: adaptor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MRLERLNYNKIKIFLTFDDLSERGLTKEDLWRNAPKVQQLFRDMMQEANKELGFEADGPIAVEVFSLQAQGMVVIVTKEN
QEMDTDDEFRDEFIEMQVTLDESEHILYEFATLDDVINLSNRLYNLGVTGGKLYTWDERFYLWVEEEEQIQLLKADFIAI
LAEYGNPSTATIYRIMEYGKELMDVNAIEQIHNYFVKKQNLS

Sequences:

>Translated_202_residues
MRLERLNYNKIKIFLTFDDLSERGLTKEDLWRNAPKVQQLFRDMMQEANKELGFEADGPIAVEVFSLQAQGMVVIVTKEN
QEMDTDDEFRDEFIEMQVTLDESEHILYEFATLDDVINLSNRLYNLGVTGGKLYTWDERFYLWVEEEEQIQLLKADFIAI
LAEYGNPSTATIYRIMEYGKELMDVNAIEQIHNYFVKKQNLS
>Mature_202_residues
MRLERLNYNKIKIFLTFDDLSERGLTKEDLWRNAPKVQQLFRDMMQEANKELGFEADGPIAVEVFSLQAQGMVVIVTKEN
QEMDTDDEFRDEFIEMQVTLDESEHILYEFATLDDVINLSNRLYNLGVTGGKLYTWDERFYLWVEEEEQIQLLKADFIAI
LAEYGNPSTATIYRIMEYGKELMDVNAIEQIHNYFVKKQNLS

Specific function: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When ove

COG id: COG4862

COG function: function code OTN; Negative regulator of genetic competence, sporulation and motility

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mecA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008681 [H]

Pfam domain/function: PF05389 MecA [H]

EC number: NA

Molecular weight: Translated: 23791; Mature: 23791

Theoretical pI: Translated: 4.15; Mature: 4.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLERLNYNKIKIFLTFDDLSERGLTKEDLWRNAPKVQQLFRDMMQEANKELGFEADGPI
CCCCCCCCCEEEEEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCE
AVEVFSLQAQGMVVIVTKENQEMDTDDEFRDEFIEMQVTLDESEHILYEFATLDDVINLS
EEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHEEEEEEECCCCEEEEHHHHHHHHHHHH
NRLYNLGVTGGKLYTWDERFYLWVEEEEQIQLLKADFIAILAEYGNPSTATIYRIMEYGK
HHEEEECCCCCEEEEECCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
ELMDVNAIEQIHNYFVKKQNLS
HHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRLERLNYNKIKIFLTFDDLSERGLTKEDLWRNAPKVQQLFRDMMQEANKELGFEADGPI
CCCCCCCCCEEEEEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCE
AVEVFSLQAQGMVVIVTKENQEMDTDDEFRDEFIEMQVTLDESEHILYEFATLDDVINLS
EEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHEEEEEEECCCCEEEEHHHHHHHHHHHH
NRLYNLGVTGGKLYTWDERFYLWVEEEEQIQLLKADFIAILAEYGNPSTATIYRIMEYGK
HHEEEECCCCCEEEEECCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
ELMDVNAIEQIHNYFVKKQNLS
HHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]