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The map label for this gene is hepT [H]

Identifier: 218233341

GI number: 218233341

Start: 1498698

End: 1499660

Strand: Direct

Name: hepT [H]

Synonym: BCB4264_A1570

Alternate gene names: 218233341

Gene position: 1498698-1499660 (Clockwise)

Preceding gene: 218231176

Following gene: 218232884

Centisome position: 27.66

GC content: 35.62

Gene sequence:

>963_bases
ATGAAGTTACAACTTATGTACTCTTTTTTACGATCGGATATTAATGTGATAGAAAAAGAATTAAAAAAGACAGTCGCTTC
TGAACAGCCATTAGTAGAAGAGGCAGCATTACAGCTTATTGAAGCTGGTGGGAAACGAATTCGTCCTGTATTTGTGTTGC
TTGCAGGGAAATTTGGAGATTATAAGTTAGATGCGATTAAGCATGTTGCTGTTGCGTTAGAACTTATTCATATGGCTTCT
CTTGTTCACGATGATGTTATTGATGCTGCATTTTTACGACGCGGCAGTGCGACTGTGAATGCGAAATGGGGAGATCGTAT
TGCGATGTATACAGGGGACTATCTGTTCGCTAAGTCTCTTGAATGTATAACCAATATCGAAATTCCAGAGGCACATCAAG
CGTTATCACATACTATTTTAGAAGTCTGTAAAGGTGAAATTGAACAAATTAAAGATAAATACAATTATGACCAAAATTTA
AGAACGTATTTAAGAAGAATAAAGCGAAAAACAGCATTATTAATTGCCGCGAGTTGTCAATTGGGAGCGATTGCTGCTGG
TGCTAATCGTGATACGGTAAATCGTCTATTTTGGTATGGGTATTTTGTAGGAATGTCTTATCAAATTATTGATGACATTT
TAGACTTCGTTTCTACAGAAGAGAAACTTGGAAAACCTGCTGGTGGAGATTTACTACAAGGGAATATTACACTTCCTGCT
TTATATGCGATGGAAGATCCCGTACTTCGTCAGAAAATCACATCTGTACATGAAAATTCAACAGCAAGTGAAATGCAAGA
AATTATTGATGCTGTAAAAAATAGTACAGCAATTGATCAAGCATTTGCGTTTAGTGAACGTTATTTACATAAAGCTTTAG
AAATAATAAAACCACTCCCACGTGGAAAAGCAAAGTACGCATTACAAAATGTTGCAAAGTATATTGGAAAACGAAAATTT
TAA

Upstream 100 bases:

>100_bases
GTGCAAGTGAAACCATTTACTTTTGGGGTAGCAGCAATGCATTTAGGTATTAAACCAGAATCAAAATAGAAAAAAGAAGT
TTTAGGTTAAGGTGAACAAT

Downstream 100 bases:

>100_bases
GGTTTATTCTAAAAAATAAAATAATCTCTCTATTTCAAAACTATTGCACAATTGTGATAAGGGTGATAATATGTGTGTGG
GGATATACAATTACATACAT

Product: heptaprenyl diphosphate synthase component II

Products: NA

Alternate protein names: HEPPP synthase subunit 2; Spore germination protein C3 [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MKLQLMYSFLRSDINVIEKELKKTVASEQPLVEEAALQLIEAGGKRIRPVFVLLAGKFGDYKLDAIKHVAVALELIHMAS
LVHDDVIDAAFLRRGSATVNAKWGDRIAMYTGDYLFAKSLECITNIEIPEAHQALSHTILEVCKGEIEQIKDKYNYDQNL
RTYLRRIKRKTALLIAASCQLGAIAAGANRDTVNRLFWYGYFVGMSYQIIDDILDFVSTEEKLGKPAGGDLLQGNITLPA
LYAMEDPVLRQKITSVHENSTASEMQEIIDAVKNSTAIDQAFAFSERYLHKALEIIKPLPRGKAKYALQNVAKYIGKRKF

Sequences:

>Translated_320_residues
MKLQLMYSFLRSDINVIEKELKKTVASEQPLVEEAALQLIEAGGKRIRPVFVLLAGKFGDYKLDAIKHVAVALELIHMAS
LVHDDVIDAAFLRRGSATVNAKWGDRIAMYTGDYLFAKSLECITNIEIPEAHQALSHTILEVCKGEIEQIKDKYNYDQNL
RTYLRRIKRKTALLIAASCQLGAIAAGANRDTVNRLFWYGYFVGMSYQIIDDILDFVSTEEKLGKPAGGDLLQGNITLPA
LYAMEDPVLRQKITSVHENSTASEMQEIIDAVKNSTAIDQAFAFSERYLHKALEIIKPLPRGKAKYALQNVAKYIGKRKF
>Mature_320_residues
MKLQLMYSFLRSDINVIEKELKKTVASEQPLVEEAALQLIEAGGKRIRPVFVLLAGKFGDYKLDAIKHVAVALELIHMAS
LVHDDVIDAAFLRRGSATVNAKWGDRIAMYTGDYLFAKSLECITNIEIPEAHQALSHTILEVCKGEIEQIKDKYNYDQNL
RTYLRRIKRKTALLIAASCQLGAIAAGANRDTVNRLFWYGYFVGMSYQIIDDILDFVSTEEKLGKPAGGDLLQGNITLPA
LYAMEDPVLRQKITSVHENSTASEMQEIIDAVKNSTAIDQAFAFSERYLHKALEIIKPLPRGKAKYALQNVAKYIGKRKF

Specific function: Supplies heptaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7) [H]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=314, Percent_Identity=29.6178343949045, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI169808399, Length=324, Percent_Identity=22.2222222222222, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1789578, Length=321, Percent_Identity=28.9719626168224, Blast_Score=157, Evalue=7e-40,
Organism=Escherichia coli, GI1786623, Length=216, Percent_Identity=32.4074074074074, Blast_Score=92, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17505681, Length=314, Percent_Identity=32.1656050955414, Blast_Score=147, Evalue=7e-36,
Organism=Saccharomyces cerevisiae, GI6319475, Length=299, Percent_Identity=29.4314381270903, Blast_Score=135, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24651612, Length=302, Percent_Identity=29.8013245033113, Blast_Score=149, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014119
- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.30 [H]

Molecular weight: Translated: 35914; Mature: 35914

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLQLMYSFLRSDINVIEKELKKTVASEQPLVEEAALQLIEAGGKRIRPVFVLLAGKFGD
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHCHHEEEEECCCCC
YKLDAIKHVAVALELIHMASLVHDDVIDAAFLRRGSATVNAKWGDRIAMYTGDYLFAKSL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEEECCHHHHHHH
ECITNIEIPEAHQALSHTILEVCKGEIEQIKDKYNYDQNLRTYLRRIKRKTALLIAASCQ
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEECCC
LGAIAAGANRDTVNRLFWYGYFVGMSYQIIDDILDFVSTEEKLGKPAGGDLLQGNITLPA
CCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCEEECCCCCCH
LYAMEDPVLRQKITSVHENSTASEMQEIIDAVKNSTAIDQAFAFSERYLHKALEIIKPLP
HHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
RGKAKYALQNVAKYIGKRKF
CCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKLQLMYSFLRSDINVIEKELKKTVASEQPLVEEAALQLIEAGGKRIRPVFVLLAGKFGD
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHCHHEEEEECCCCC
YKLDAIKHVAVALELIHMASLVHDDVIDAAFLRRGSATVNAKWGDRIAMYTGDYLFAKSL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEEECCHHHHHHH
ECITNIEIPEAHQALSHTILEVCKGEIEQIKDKYNYDQNLRTYLRRIKRKTALLIAASCQ
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEECCC
LGAIAAGANRDTVNRLFWYGYFVGMSYQIIDDILDFVSTEEKLGKPAGGDLLQGNITLPA
CCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCEEECCCCCCH
LYAMEDPVLRQKITSVHENSTASEMQEIIDAVKNSTAIDQAFAFSERYLHKALEIIKPLP
HHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
RGKAKYALQNVAKYIGKRKF
CCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 2121900; 9720033 [H]