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The map label for this gene is mtnN [H]

Identifier: 218233297

GI number: 218233297

Start: 2765529

End: 2766242

Strand: Reverse

Name: mtnN [H]

Synonym: BCB4264_A2883

Alternate gene names: 218233297

Gene position: 2766242-2765529 (Counterclockwise)

Preceding gene: 218232542

Following gene: 218234423

Centisome position: 51.05

GC content: 34.31

Gene sequence:

>714_bases
ATGAACAGAATCGGCATTATCGGAGCAATGCAAATTGAAATAGATTTACTTTTAGAAAAGCTAGTAATACAAGAAGAACA
GACAATAGCGGGAATGCCATTTTATATTGGAGAATTCATGGGAACAGAAGTAATTATTGCACGTTCTGGTGTAGGGAAAG
TAAATGCAGCTGCATGTGCGCAAACATTAATTCATAAATTTAATGTAGACTCTATCATCAATACGGGCGTTGCTGGTGGA
TTACATCCAGATGTAAAAGTTGGTGATGTAGTTATTTCAACGAATGTTACCCATCATGATGTAAGTAAAAATCAAATGAA
AAAATTATTCCCGTTTCAAGAGGAGTTTATTGCAAGTAAGGAATTGATAGAGTTAGCACGTAAAGCATGTAACAGTAATA
GTTCAAATATTCAAGCTCACGAAGGAAGAATTGTAAGTGGTGAATGTTTTGTTGAAGATTCAAAGTTAAAGGCAAAATTA
ATAGATGAATACGCACCTCATTGTACAGAAATGGAAGGTGCAGCAATTGGACATGTTGCCTACATAAATGATATACCGTT
TCTTGTTATACGATGTATTTCTGACAGTGCAGATGATGAAGCTCAAGTTTCTTATGATGATTTCGCGAAAACTGCTGCGA
ATTATTGCTCAGAAATTATTATTGAGATGCTTAAAAATATATCTGGTAAAACTATAGTCCAAAAGGAGAGATAG

Upstream 100 bases:

>100_bases
AGCCGAAAAGATTAAAGAGACAACTTGTACTTCCGAAATTTTTATTGTCGGTTATGTCAGAGAGGATTAAAGGGATTAAT
TAATAAAGGGGACTACATAC

Downstream 100 bases:

>100_bases
GAATGTTACAAGCATTAATTTTTGATATGGACGGAACATTATTTCAAACAGATAAAATTTTAGAATTATCGTTGGATGAT
ACTTTTGATCACTTAAGATC

Product: bifunctional 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase/phosphatase

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MNRIGIIGAMQIEIDLLLEKLVIQEEQTIAGMPFYIGEFMGTEVIIARSGVGKVNAAACAQTLIHKFNVDSIINTGVAGG
LHPDVKVGDVVISTNVTHHDVSKNQMKKLFPFQEEFIASKELIELARKACNSNSSNIQAHEGRIVSGECFVEDSKLKAKL
IDEYAPHCTEMEGAAIGHVAYINDIPFLVIRCISDSADDEAQVSYDDFAKTAANYCSEIIIEMLKNISGKTIVQKER

Sequences:

>Translated_237_residues
MNRIGIIGAMQIEIDLLLEKLVIQEEQTIAGMPFYIGEFMGTEVIIARSGVGKVNAAACAQTLIHKFNVDSIINTGVAGG
LHPDVKVGDVVISTNVTHHDVSKNQMKKLFPFQEEFIASKELIELARKACNSNSSNIQAHEGRIVSGECFVEDSKLKAKL
IDEYAPHCTEMEGAAIGHVAYINDIPFLVIRCISDSADDEAQVSYDDFAKTAANYCSEIIIEMLKNISGKTIVQKER
>Mature_237_residues
MNRIGIIGAMQIEIDLLLEKLVIQEEQTIAGMPFYIGEFMGTEVIIARSGVGKVNAAACAQTLIHKFNVDSIINTGVAGG
LHPDVKVGDVVISTNVTHHDVSKNQMKKLFPFQEEFIASKELIELARKACNSNSSNIQAHEGRIVSGECFVEDSKLKAKL
IDEYAPHCTEMEGAAIGHVAYINDIPFLVIRCISDSADDEAQVSYDDFAKTAANYCSEIIIEMLKNISGKTIVQKER

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786354, Length=231, Percent_Identity=36.7965367965368, Blast_Score=123, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 25960; Mature: 25960

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRIGIIGAMQIEIDLLLEKLVIQEEQTIAGMPFYIGEFMGTEVIIARSGVGKVNAAACA
CCCEEEEEEEHHHHHHHHHHHHHHCCHHHCCCCHHHHHHCCCEEEEEECCCCCCHHHHHH
QTLIHKFNVDSIINTGVAGGLHPDVKVGDVVISTNVTHHDVSKNQMKKLFPFQEEFIASK
HHHHHHCCHHHHHHCCCCCCCCCCCEECCEEEECCCCHHCCCHHHHHHHCCHHHHHHHHH
ELIELARKACNSNSSNIQAHEGRIVSGECFVEDSKLKAKLIDEYAPHCTEMEGAAIGHVA
HHHHHHHHHHCCCCCCEEECCCEEECCEEEEECCHHHHHHHHHHCCCCCCCCCCCEEEEE
YINDIPFLVIRCISDSADDEAQVSYDDFAKTAANYCSEIIIEMLKNISGKTIVQKER
ECCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCC
>Mature Secondary Structure
MNRIGIIGAMQIEIDLLLEKLVIQEEQTIAGMPFYIGEFMGTEVIIARSGVGKVNAAACA
CCCEEEEEEEHHHHHHHHHHHHHHCCHHHCCCCHHHHHHCCCEEEEEECCCCCCHHHHHH
QTLIHKFNVDSIINTGVAGGLHPDVKVGDVVISTNVTHHDVSKNQMKKLFPFQEEFIASK
HHHHHHCCHHHHHHCCCCCCCCCCCEECCEEEECCCCHHCCCHHHHHHHCCHHHHHHHHH
ELIELARKACNSNSSNIQAHEGRIVSGECFVEDSKLKAKLIDEYAPHCTEMEGAAIGHVA
HHHHHHHHHHCCCCCCEEECCCEEECCEEEEECCHHHHHHHHHHCCCCCCCCCCCEEEEE
YINDIPFLVIRCISDSADDEAQVSYDDFAKTAANYCSEIIIEMLKNISGKTIVQKER
ECCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA