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The map label for this gene is recG [H]

Identifier: 218233045

GI number: 218233045

Start: 3874365

End: 3876413

Strand: Reverse

Name: recG [H]

Synonym: BCB4264_A3954

Alternate gene names: 218233045

Gene position: 3876413-3874365 (Counterclockwise)

Preceding gene: 218232350

Following gene: 218232392

Centisome position: 71.53

GC content: 39.97

Gene sequence:

>2049_bases
TTGAATGATGTTGTACAAGTTCCTGTTACGGATGTAAAGGGGATCGGAGGAGAAACATCTGAGTTACTACATGAGATGGG
TATTTATACAGTTTCTCATCTATTAGAACATTTTCCATACCGTTATGAAGATTATGCGATGAAAGATCTTGCTGAAGTAA
AGCATGATGAACGTGTAACGGTTGAAGGGAAGATTCATAGTGCTCCTTTGCTGCAATATTATGGTAAGAAGAAATCGCGT
TTAACAGTTCGTGTTCTCGTCGGTCGTTATTTAATTACGGCGGTATGTTTTAATAGGCCTTACTATAAGCAAAAATTAAA
GTTAGATGAAACGGTAACGATTACTGGTAAATGGGATCAACATCGTCAAACAATTGCTGTATCAGAACTTCATTTTGGGC
CGGTTGTACGTCAACAAGAAGTGGAACCTGTTTATTCAGTAAAGGGGAAACTTACAGTAAAACAGATGCGTCGTTTTATT
GCTCAAGCGTTAAAGGAATATGGAGATTCTATAGTCGAAGTGTTACCGGATGGTTTGTTAGGGCGATATAAATTATTACC
AAGATATGAAGCGCTTAGGGCATTGCATTTTCCGGTAGGACAGGAAGATTTGAAGCAAGCGCGTCGCCGTTTTGTATATG
AAGAATTTTTCTTATTTCAGCTGAAAATGCAAACGCTCCGGAAAATGGAGAGGGAAAATTCAAAAGGGACGAAGAAAGAG
ATTCCGTCAGTAGAATTACAAGAATTTATCGATGCACTGCCGTTTCCATTAACGGGTGCGCAGCGCCGAGTTGTAGATGA
AATTTTGAAAGATATGACATCTCCTTATCGGATGAACCGACTATTGCAAGGTGACGTTGGTTCTGGGAAAACAGTTGTTG
CTGCGATTGGCCTTTATGCATCGAAATTAGCCCATTATCAAGGTGCTTTAATGGTTCCTACAGAAATTTTAGCTGAGCAA
CATTATCAGTCGCTTGCTGAAACGTTTTCGCATTTTGGTATGAAGGTGGAACTGTTAACAAGTTCTGTTAAAGGGGCGAG
ACGTCGAGAAATTTTAGCGAAGTTAGAACAAGGAGAAATAGATATTCTTGTTGGAACGCATGCCTTAATTCAAGATGAAG
TTATATTTCATAGGTTGGGTCTCGTTATTACAGATGAACAGCATCGATTTGGTGTAGCGCAGCGCCGAGTTTTACGGGAG
AAAGGTGAAAGTCCAGATGTATTATTTATGACAGCGACACCAATTCCGCGTACGCTTGCAATTACTGCATTTGGAGAGAT
GGATGTTTCGATAATCGATGAGATGCCAGCAGGTAGAAAGGTGATTGAAACATACTGGGCAAAACATGATATGTTAGATC
GCGTTCTCGGTTTCGTTGAAAAGGAGATAAAAAAAGGAAGACAGGCATACGTTATTTGTCCTTTAATTGAAGAATCTGAG
AAACTTGATGTGCAAAATGCTATCGACTTACATAGTATGCTGACGCATCATTACCAAGGGAAATGCCAAGTTGGATTGAT
GCATGGGAGATTATCGTCTCAGGAAAAAGAAGAGATAATGGGACAGTTTAGTGAAAATAAAGTACAAATTCTTGTATCGA
CAACAGTTGTTGAAGTAGGTGTGAACGTACCGAATGCGACTGTAATGGTTATTTATGATGCAGAACGTTTCGGTTTATCG
CAGCTTCATCAGCTTAGAGGGCGTGTCGGCCGTGGTAGTGAACAATCATATTGTTTATTAATAGCAGACCCTAAATCAGA
AACAGGGAAAGAAAGAATGCGCATAATGACTGAAACAAATGATGGATTTGTATTGTCAGAAAAAGATTTAGAATTACGAG
GTCCTGGAGATTTCTTTGGGAGTAAGCAAAGTGGCTTACCAGAATTTAAGGTTGCTGACATGGTACATGATTATCGAGCG
TTAGAAACAGCAAGGCAAGATGCGGCGATACTAGTAGATTCAGAAGCGTTTTGGCATAATGATCAGTATGCTGCCTTGCG
TACGTATCTTGATGGGACAGGTGTGTTCCAAGGAGAGAAGCTCGATTAA

Upstream 100 bases:

>100_bases
CTATGATAGAATATATAAGGTGAAAGAGAGCGATTACAGATGCTAATTGGTACTCAAATAAAATGCAATAAAGAAAATAA
TGTGACGGGGTGTGAGAATC

Downstream 100 bases:

>100_bases
AGGGAGTCAACAAAAGTTTTTGTTGCATTCTACTTTTAATGATTATATACTACTGTTAGTACCTAGTCATAAAAATGGAT
GGTGCGGTATGAAAAAAAGA

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 682; Mature: 682

Protein sequence:

>682_residues
MNDVVQVPVTDVKGIGGETSELLHEMGIYTVSHLLEHFPYRYEDYAMKDLAEVKHDERVTVEGKIHSAPLLQYYGKKKSR
LTVRVLVGRYLITAVCFNRPYYKQKLKLDETVTITGKWDQHRQTIAVSELHFGPVVRQQEVEPVYSVKGKLTVKQMRRFI
AQALKEYGDSIVEVLPDGLLGRYKLLPRYEALRALHFPVGQEDLKQARRRFVYEEFFLFQLKMQTLRKMERENSKGTKKE
IPSVELQEFIDALPFPLTGAQRRVVDEILKDMTSPYRMNRLLQGDVGSGKTVVAAIGLYASKLAHYQGALMVPTEILAEQ
HYQSLAETFSHFGMKVELLTSSVKGARRREILAKLEQGEIDILVGTHALIQDEVIFHRLGLVITDEQHRFGVAQRRVLRE
KGESPDVLFMTATPIPRTLAITAFGEMDVSIIDEMPAGRKVIETYWAKHDMLDRVLGFVEKEIKKGRQAYVICPLIEESE
KLDVQNAIDLHSMLTHHYQGKCQVGLMHGRLSSQEKEEIMGQFSENKVQILVSTTVVEVGVNVPNATVMVIYDAERFGLS
QLHQLRGRVGRGSEQSYCLLIADPKSETGKERMRIMTETNDGFVLSEKDLELRGPGDFFGSKQSGLPEFKVADMVHDYRA
LETARQDAAILVDSEAFWHNDQYAALRTYLDGTGVFQGEKLD

Sequences:

>Translated_682_residues
MNDVVQVPVTDVKGIGGETSELLHEMGIYTVSHLLEHFPYRYEDYAMKDLAEVKHDERVTVEGKIHSAPLLQYYGKKKSR
LTVRVLVGRYLITAVCFNRPYYKQKLKLDETVTITGKWDQHRQTIAVSELHFGPVVRQQEVEPVYSVKGKLTVKQMRRFI
AQALKEYGDSIVEVLPDGLLGRYKLLPRYEALRALHFPVGQEDLKQARRRFVYEEFFLFQLKMQTLRKMERENSKGTKKE
IPSVELQEFIDALPFPLTGAQRRVVDEILKDMTSPYRMNRLLQGDVGSGKTVVAAIGLYASKLAHYQGALMVPTEILAEQ
HYQSLAETFSHFGMKVELLTSSVKGARRREILAKLEQGEIDILVGTHALIQDEVIFHRLGLVITDEQHRFGVAQRRVLRE
KGESPDVLFMTATPIPRTLAITAFGEMDVSIIDEMPAGRKVIETYWAKHDMLDRVLGFVEKEIKKGRQAYVICPLIEESE
KLDVQNAIDLHSMLTHHYQGKCQVGLMHGRLSSQEKEEIMGQFSENKVQILVSTTVVEVGVNVPNATVMVIYDAERFGLS
QLHQLRGRVGRGSEQSYCLLIADPKSETGKERMRIMTETNDGFVLSEKDLELRGPGDFFGSKQSGLPEFKVADMVHDYRA
LETARQDAAILVDSEAFWHNDQYAALRTYLDGTGVFQGEKLD
>Mature_682_residues
MNDVVQVPVTDVKGIGGETSELLHEMGIYTVSHLLEHFPYRYEDYAMKDLAEVKHDERVTVEGKIHSAPLLQYYGKKKSR
LTVRVLVGRYLITAVCFNRPYYKQKLKLDETVTITGKWDQHRQTIAVSELHFGPVVRQQEVEPVYSVKGKLTVKQMRRFI
AQALKEYGDSIVEVLPDGLLGRYKLLPRYEALRALHFPVGQEDLKQARRRFVYEEFFLFQLKMQTLRKMERENSKGTKKE
IPSVELQEFIDALPFPLTGAQRRVVDEILKDMTSPYRMNRLLQGDVGSGKTVVAAIGLYASKLAHYQGALMVPTEILAEQ
HYQSLAETFSHFGMKVELLTSSVKGARRREILAKLEQGEIDILVGTHALIQDEVIFHRLGLVITDEQHRFGVAQRRVLRE
KGESPDVLFMTATPIPRTLAITAFGEMDVSIIDEMPAGRKVIETYWAKHDMLDRVLGFVEKEIKKGRQAYVICPLIEESE
KLDVQNAIDLHSMLTHHYQGKCQVGLMHGRLSSQEKEEIMGQFSENKVQILVSTTVVEVGVNVPNATVMVIYDAERFGLS
QLHQLRGRVGRGSEQSYCLLIADPKSETGKERMRIMTETNDGFVLSEKDLELRGPGDFFGSKQSGLPEFKVADMVHDYRA
LETARQDAAILVDSEAFWHNDQYAALRTYLDGTGVFQGEKLD

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=660, Percent_Identity=39.2424242424242, Blast_Score=399, Evalue=1e-112,
Organism=Escherichia coli, GI1787357, Length=385, Percent_Identity=37.6623376623377, Blast_Score=267, Evalue=2e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 77597; Mature: 77597

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDVVQVPVTDVKGIGGETSELLHEMGIYTVSHLLEHFPYRYEDYAMKDLAEVKHDERVT
CCCEEECCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEE
VEGKIHSAPLLQYYGKKKSRLTVRVLVGRYLITAVCFNRPYYKQKLKLDETVTITGKWDQ
EECCCCCCHHHHHHCCCCCCEEHHHHHHHHHHHHHHHCCCHHHHHCCCCCEEEEECCCCC
HRQTIAVSELHFGPVVRQQEVEPVYSVKGKLTVKQMRRFIAQALKEYGDSIVEVLPDGLL
CCCEEEEEHCCCCCCCCHHCCCHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCHH
GRYKLLPRYEALRALHFPVGQEDLKQARRRFVYEEFFLFQLKMQTLRKMERENSKGTKKE
HHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHC
IPSVELQEFIDALPFPLTGAQRRVVDEILKDMTSPYRMNRLLQGDVGSGKTVVAAIGLYA
CCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHH
SKLAHYQGALMVPTEILAEQHYQSLAETFSHFGMKVELLTSSVKGARRREILAKLEQGEI
HHHHHHCCCEECHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHCHHHHHHHHHHHCCCCE
DILVGTHALIQDEVIFHRLGLVITDEQHRFGVAQRRVLREKGESPDVLFMTATPIPRTLA
EEEECCHHHHHHHHHHHHHCEEEECCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEE
ITAFGEMDVSIIDEMPAGRKVIETYWAKHDMLDRVLGFVEKEIKKGRQAYVICPLIEESE
EEEECCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCC
KLDVQNAIDLHSMLTHHYQGKCQVGLMHGRLSSQEKEEIMGQFSENKVQILVSTTVVEVG
CCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEEEEEEEEEEC
VNVPNATVMVIYDAERFGLSQLHQLRGRVGRGSEQSYCLLIADPKSETGKERMRIMTETN
CCCCCCEEEEEECCHHCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHEEEEEECC
DGFVLSEKDLELRGPGDFFGSKQSGLPEFKVADMVHDYRALETARQDAAILVDSEAFWHN
CCEEEECCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECHHHCCC
DQYAALRTYLDGTGVFQGEKLD
CCHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNDVVQVPVTDVKGIGGETSELLHEMGIYTVSHLLEHFPYRYEDYAMKDLAEVKHDERVT
CCCEEECCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEE
VEGKIHSAPLLQYYGKKKSRLTVRVLVGRYLITAVCFNRPYYKQKLKLDETVTITGKWDQ
EECCCCCCHHHHHHCCCCCCEEHHHHHHHHHHHHHHHCCCHHHHHCCCCCEEEEECCCCC
HRQTIAVSELHFGPVVRQQEVEPVYSVKGKLTVKQMRRFIAQALKEYGDSIVEVLPDGLL
CCCEEEEEHCCCCCCCCHHCCCHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCHH
GRYKLLPRYEALRALHFPVGQEDLKQARRRFVYEEFFLFQLKMQTLRKMERENSKGTKKE
HHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHC
IPSVELQEFIDALPFPLTGAQRRVVDEILKDMTSPYRMNRLLQGDVGSGKTVVAAIGLYA
CCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHH
SKLAHYQGALMVPTEILAEQHYQSLAETFSHFGMKVELLTSSVKGARRREILAKLEQGEI
HHHHHHCCCEECHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHCHHHHHHHHHHHCCCCE
DILVGTHALIQDEVIFHRLGLVITDEQHRFGVAQRRVLREKGESPDVLFMTATPIPRTLA
EEEECCHHHHHHHHHHHHHCEEEECCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEE
ITAFGEMDVSIIDEMPAGRKVIETYWAKHDMLDRVLGFVEKEIKKGRQAYVICPLIEESE
EEEECCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCC
KLDVQNAIDLHSMLTHHYQGKCQVGLMHGRLSSQEKEEIMGQFSENKVQILVSTTVVEVG
CCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEEEEEEEEEEC
VNVPNATVMVIYDAERFGLSQLHQLRGRVGRGSEQSYCLLIADPKSETGKERMRIMTETN
CCCCCCEEEEEECCHHCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHEEEEEECC
DGFVLSEKDLELRGPGDFFGSKQSGLPEFKVADMVHDYRALETARQDAAILVDSEAFWHN
CCEEEECCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECHHHCCC
DQYAALRTYLDGTGVFQGEKLD
CCHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]